|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 第 7 肺癌症 TNM 分类和阶段系统: 变化和含意的评论显示文摘 Lung cancer is the most common cause of death from cancer in males,accounting for more than 1.4 million deaths in 2008.It is a growing concern in China,Asia and Africa as well.Accurate staging of the disease is an important part of the management as it provides estimation of patient’s prognosis and identifies treatment sterategies.It also helps to build a database for future staging projects.A major revision of lung cancer staging has been announced with effect from January 2010.The new classification is based on a larger surgical and non-surgical cohort of patients,and thus more accurate in terms of outcome prediction compared to the previous classification.There are several original papers regarding this new classification which give comprehensive description of the methodology,the changes in the staging and the statistical analysis.This overview is a simplified description of the changes in the new classification and their potential impact on patients’ treatment and prognosis. | Saeed Mirsadraee Dilip Oswal Yalda Alizadeh Andrea Caulo Edwin JR van Beek | 2012 | World Journal of Radiology2012，4，4： | 15 |
| 2 | Hepatitis B and C virus-induced hepatitis: Apoptosis, autophagy, and unfolded protein response显示文摘AIM: To investigate the co-incidence of apoptosis, autophagy, and unfolded protein response(UPR) in hepatitis B(HBV) and C(HCV) infected hepatocytes.METHODS: We performed immunofluorescence confocal microscopy on 10 liver biopsies from HBV and HCV patients and tissue microarrays of HBV positive liver samples. We used specific antibodies for LC3β, cleaved caspase-3, BIP(GRP78), and XBP1 to detect autophagy, apoptosis and UPR, respectively. AntiHCV NS3 and anti-HBs antibodies were also used to confirm infection. We performed triple blind counting of events to determine the co-incidence of autophagy(LC3β punctuate), apoptosis(cleaved caspase-3), and unfolded protein response(GRP78) with HBV and HCV infection in hepatocytes. All statistical analyses were performed using SPSS software for Windows(Version 16 SPSS Inc, Chicago, IL, United States). P-values < 0.05 were considered statistically significant. Statistical analyses were performed with Mann-Whitney test to compare incidence rates for autophagy, apoptosis, and UPR in HBV- and HCV-infected cells and adjacent noninfected cells.RESULTS: Our results showed that infection of hepatocytes with either HBV and HCV induces significant increase(P < 0.001) in apoptosis(cleavage of caspase-3), autophagy(LC3β punctate), and UPR(increase in GRP78 expression) in the HCV- and HBVinfected cells, as compared to non-infected cells of the same biopsy sections. Our tissue microarray immunohistochemical expression analysis of LC3β in HBV^(Neg) and HBV^(Pos) revealed that majority of HBVinfected hepatocytes display strong positive stainingfor LC3β. Interestingly, although XBP splicing in HBVinfected cells was significantly higher(P < 0.05), our analyses show a slight increase of XBP splicing was in HCV-infected cells(P > 0.05). Furthermore, our evaluation of patients with HBV and HCV infection based on stage and grade of the liver diseases revealed no correlation between these pathological findings and induction of apoptosis, autophagy, and UPR.CONCLUSION: The results of this study indicate that HCV and HBV infection activates apoptosis, autophagy and UPR, but slightly differently by each virus. Further studies are warranted to elucidate the interconnections between these pathways in relation to pathology of HCV and HBV in the liver tissue. | Behzad Yeganeh Adel Rezaei Moghadam Javad Alizadeh Emilia Wiechec Seyed Moayed Alavian Mohammad Hashemi Bita Geramizadeh Afshin Samali Kamran Bagheri Lankarani Martin Post Payam Peymani Kevin M Coombs Saeid Ghavami | 2015 | World Journal of Gastroenterology2015，21，47： | 13 |
| 3 | Computational fluid dynamics(CFD) simulation of effect of baffles on separation in mixer settler显示文摘The main ideas in the development of the solvent extraction mixer settler focused on achieving clean phase separation,minimizing the loss of the reagents and decreasing the surface area of the settlers.The role of baffles in a mechanically agitated vessel is to ensure even distribution,reduce settler turbulence,promote the stability of power drawn by the impeller and to prevent swirling and vortexing of liquid,thus,greatly improving the mixing of liquid.The insertion of the appropriate number of baffles clearly improves the extent of liquid mixing.However,excessive baffling would interrupt liquid mixing and lengthen the mixing time.Computational fluid dynamics(CFD) provides a tool for determining detailed information on fluid flow(hydrodynamics) which is necessary for modeling subprocesses in mixer settler.A total of 54 final CFD runs were carried out representing different combinations of variables like number of baffles,density and impeller speed.CFD data shows that amount of separation increases with increasing baffles number and decreasing impeller speed. | Mohsen Ostad Shabani Ali Mazahery Mehdi Alizadeh Ali Asghar Tofigh Mohammad Reza Rahimipour Mansour Razavi Alireza Kolahi | 2012 | International Journal of Mining Science and Technology2012，22，5： | 12 |
| 4 | Predictive value and main determinants of abnormal features of intraoperative cholangiography during cholecystectomy显示文摘BACKGROUND:The major issue with intraoperative cholangiography (IOC) is whether its diagnostic accuracy for common bile duct (CBD) stones matches that of other diagnostic procedures,and thus,whether it will become a routine diagnostic procedure.The current study aimed to address the main determinants of CBD stone diagnosis in IOC among an Iranian population.METHODS:In a retrospective review database-based study conducted in Taleghani Hospital in Tehran between 2006 and 2008,baseline data and perioperative information of 2060 patients (male to female ratio 542:1518,mean age 53.7 years) who were candidates for cholecystectomy and underwent concomitant IOC for confirming CBD stones were reviewed.The predictive power of this procedure for diagnosis of abnormal biliary ducts with the focus on biliary stones was determined.RESULTS:Overall mortality and morbidity following cholecystectomy in the study population were 0.6% and 2.6%,respectively.Both early mortality and morbidity due to cholecystectomy were higher in male than female.The prevalence of CBD stones in IOC was 3.4% (5.2% in male and 2.8% in female,P=0.008).Among those without gallstones,8.7% had CBD stones and only 3.1% had concomitant gallstones and CBD stones.The main predictors of stone appearance as an abnormal feature of IOC during cholecystectomy were:advanced age (OR=1.022,P=0.001),male gender (OR=1.498,P=0.050),history of abdominal surgery (OR=1.543,P=0.040) and preoperative endoscopic retrograde cholangiopancreatography (OR=5.400,P<0.001).CONCLUSIONS:IOC is a safe and accurate method for the assessment of bile duct anatomy and stones.Therefore,the routine use of IOC within cholecystectomy seems reasonable and is recommended. | Shahram Yousefpour Azary Heshmat Kalbasi Ali Setayesh Mirhadi Mousavi Asad Hashemi Mahsa Khodadoostan Mohammad Reza Zali Amir Houshang Mohammad Alizadeh | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 11 |
| 5 | Turbine blade temperature calculation and life estimation-a sensitivity analysis显示文摘The overall operating cost of the modern gas turbines is greatly influenced by thedurability of hot section components operating at high temperatures.In turbine operatingconditions,some defects may occur which can decrease hot section life.In the present paper,methods used for calculating blade temperature and life are demonstrated and validated.Usingthese methods,a set of sensitivity analyses on the parameters affecting temperature and life ofa high pressure,high temperature turbine first stage blade is carried out.Investigateduncertainties are:(1)blade coating thickness,(2)coolant inlet pressure and temperature(asa result of secondary air system),and(3)gas turbine load variation.Results show thatincreasing thermal bamier coating thickness by 3 times,leads to rise in the blade life by 9times.In addition,considering inlet cooling temperature and pressure,deviation in temperaturehas greater effect on blade life.One of the interesting points that can be realized from theresults is that 300 hours operation at 70%load can be equal to one hour operation atbase load. | Majid Rezazadeh Reyhani Mohammad Alizadeh Alireza Fathi Hiwa Khaledid | 2013 | Propulsion and Power Research2013，2，2： | 9 |
| 6 | Intra-familial prevalence of hepatitis B virologic markers in HBsAg positive family members in Nahavand, Iran显示文摘AIM: To determine the prevalence of hepatitis B in Nahavand and evaluate the HBsAg positive prevalence in families with a member who was confirmed to have HBV infection.METHODS: This study was performed in two phases. In the first phase, 1 824 subjects in Nahavand city were selected. The interviewers visited the houses of chosen families to fill the questionnaire and take the blood samples.All subjects signed an informed consent before interviews and blood sampling. The samples were evaluated for HBV virologic markers. In the second phase, 115 HBsAg-positive cases were enrolled and evaluated for HBV virologic markers.RESULTS: The prevalence of positive HBsAg in Nahavand was 2.3%. The most frequent relatives of index cases were sons and daughters (32.2% and 23.5% respectively).Twelve (11%) of all family members were HBsAg positive.Fifty (56.2%) were isolated HBsAb positive and only one person (2.5%) was isolated HBcAb positive. The higher rates of HBsAg marker were detected in the brothers (1-25%) and fathers (1-12.5%). The infection rate in husbands and wives of index cases was 10%. Only two (16.7%) of all HBsAg-positive participants reported previous HBV vaccination.CONCLUSION: The prevalence of intra-familial HBV infection is lower in Nahavand of Iran compared to other studies.More attention should be paid to HBV vaccination and risk-lowering activities. | Amir Houshang Mohammad Alizadeh Mitra Ranjbar Shahin Ansari Seyed Moayed Alavian Hamid Mohaghegh Shalmani Leila Hekmat Mohammad Reza Zali | 2005 | World Journal of Gastroenterology2005，11，31： | 8 |
| 7 | 超细晶Al5083合金和碳化硼增强Al5083基复合材料的室温和高温干滑动摩擦磨损行为显示文摘讨论机械球磨Al5083合金和Al5083−5wt.%B4C复合材料在室温和200°C下的摩擦行为和磨损机制。结果表明,由于常温下的氧化磨损,形成可保护试样表面的机械混合层。在室温和80 N载荷下,Al5083和Al5083−5wt.%B4C球磨样品有磨损迹象,但体积磨损量有限,磨损率分别为5.8×10−7和4.4×10−7mm3/(m·N)。在200°C和80 N载荷下,球磨Al5083样品磨损严重,磨损率达10.8×10−7 mm3/(m·N);Al5083−5wt.%B4C样品的磨损较轻,局部出现三体磨损,磨损率为5.3×10−7 mm3/(m·N)。位错钉扎和Hall−Petch理论等强化机制、高硬度和载荷传递效应是决定Al5083−5wt.%B4C复合材料磨损行为的关键因素。另一方面,球磨Al5083样品在200°C下磨损率较高可能与其局部晶粒长大和硬度下降有关。 | Matin SAESSI Ali ALIZADEH Alireza ABDOLLAHI | 2021 | Transactions of Nonferrous Metals Society of China2021，31，1： | 7 |
| 8 | 微泡钻井液流变性显示文摘鉴于微泡钻井液在衰竭油气藏钻井中的成功应用,通过实验测试和数据分析研究了微泡钻井液的流变性及稳定性。配制了一种典型的微泡钻井液,在不同温度下对其黏度进行测试,分别采用幂律模型、宾汉塑性模型和Herschel-Bulkley模型对测试数据进行了拟合,发现Herschel-Bulkley模型更能准确描述不同温度下微泡形成前后钻井液的流变性。根据Herschel-Bulkley模型拟合结果,温度升高会提高微泡钻井液的剪切稀释程度,微泡形成后钻井液的静切力和井眼净化能力提高,且在高温下微泡钻井液性能不会明显减弱。低剪切速率下微泡钻井液具有较高的黏度,可以保证良好的孔隙堵塞效果。微泡尺寸增长速率及静态析出实验中液体析出速率可作为评价微泡稳定性的指标:微泡尺寸随时间增加增长缓慢且寿命较长,静态析出实验中液体析出速率低,说明微泡钻井液具有良好的稳定性。 | KHAMEHCHI Ehsan TABIBZADEH Shahin ALIZADEH Ali | 2016 | 石油勘探与开发2016，43，6： | 7 |
| 9 | 不同气蚀次数球阀空化的数值研究(英文)显示文摘空化是控制阀中的一种破坏性现象。为了延缓空化,采用一种多孔圆柱板,称为trim。在此之前,我们曾研究过孔板直径和不同类型的trim的影响。本文采用4种不同工况(无trim,1,2和3 trims)对球阀进行数值分析,分析了trim的数量对气蚀强度、形成区域和空化起始点的影响。结果表明,与不加trim的阀门相比,增加一个或两个trim可以降低气蚀的强度,延缓空化的发生。然而,在使用两到三个trims的情况下,空化的强度和起始点没有明显的差异。由于trim生产成本高,流量系数严重下降,将trim数量增加到3个以上在经济和技术上都是不合理的。 | Hamidreza YAGHOUBI Seyed Amir Hossein MADANI Mansour ALIZADEH | 2018 | Journal of Central South University2018，25，11： | 6 |
| 10 | Estimation of meteorological drought indices based on AgMERRA precipitation data and station-observed precipitation data显示文摘Meteorological drought is a natural hazard that can occur under all climatic regimes. Monitoring the drought is a vital and important part of predicting and analyzing drought impacts. Because no single index can represent all facets of meteorological drought, we took a multi-index approach for drought monitoring in this study. We assessed the ability of eight precipitation-based drought indices(SPI(Standardized Precipitation Index), PNI(Percent of Normal Index), DI(Deciles index), EDI(Effective drought index), CZI(China-Z index), MCZI(Modified CZI), RAI(Rainfall Anomaly Index), and ZSI(Z-score Index)) calculated from the station-observed precipitation data and the Ag MERRA gridded precipitation data to assess historical drought events during the period 1987–2010 for the Kashafrood Basin of Iran. We also presented the Degree of Dryness Index(DDI) for comparing the intensities of different drought categories in each year of the study period(1987–2010). In general, the correlations among drought indices calculated from the Ag MERRA precipitation data were higher than those derived from the station-observed precipitation data. All indices indicated the most severe droughts for the study period occurred in 2001 and 2008. Regardless of data input source, SPI, PNI, and DI were highly inter-correlated(R^2=0.99). Furthermore, the higher correlations(R^2=0.99) were also found between CZI and MCZI, and between ZSI and RAI. All indices were able to track drought intensity, but EDI and RAI showed higher DDI values compared with the other indices. Based on the strong correlation among drought indices derived from the Ag MERRA precipitation data and from the station-observed precipitation data, we suggest that the Ag MERRA precipitation data can be accepted to fill the gaps existed in the station-observed precipitation data in future studies in Iran. In addition, if tested by station-observed precipitation data, the Ag MERRA precipitation data may be used for the data-lacking areas. | Nasrin SALEHNIA Amin ALIZADEH Hossein SANAEINEJAD Mohammad BANNAYAN Azar ZARRIN Gerrit HOOGENBOOM | 2017 | Journal of Arid Land2017，9，6： | 6 |
| 11 | Tacrolimus and mycophenolate mofetil as second-line treatment in autoimmune hepatitis:Is the evidence of sufficient quality to develop recommendations?显示文摘BACKGROUND The standard management of autoimmune hepatitis(AIH)is based on corticosteroids,alone or in combination with azathioprine.Second-line treatments are needed for patients who have refractory disease.However,high-quality data on the alternative management of AIH are scarce.AIM To evaluate the efficacy and safety of tacrolimus and mycophenolate mofetil(MMF)and the quality of evidence by using the Grading of Recommendations Assessment,Development and Evaluation approach(GRADE).METHODS A systematic review and meta-analysis of the available data were performed.We calculated pooled event rates for three outcome measures:Biochemical remission,adverse events,and mortality,with their corresponding 95%confidence intervals(CI).RESULTS The pooled biochemical remission rate was 68.9%(95%CI:60.4-76.2)for tacrolimus,and 59.6%(95%CI:54.8-64.2)for MMF,and rates of adverse events were 25.5%(95%CI:12.4-45.3)for tacrolimus and 24.1%(95%CI:15.4-35.7)for MMF.The pooled mortality rate was estimated at 11.5%(95%CI:7.1-18.1)for tacrolimus and 9.01%(95%CI:6.2-12.8)for MMF.Pooled biochemical remission rates for tacrolimus and MMF in patients with intolerance to standard therapy were 56.6%(CI:43.4-56.6)vs 73.5%(CI:58.1-84.7),and among non-responders were 59.1%(CI:48.7-68.8)vs 40.8%(CI:32.3-50.0),respectively.Moreover,the overall quality assessments using GRADE proved to be very low for all our outcomes in both treatment groups.CONCLUSION Tacrolimus and MMF are in practice considered effective for patients with AIH who are non-responders or intolerant to first-line treatment,but we found no high-quality evidence to support this statement. | Mohammadreza Abdollahi Neda Khalilian Ekrami Morteza Ghojazadeh H Marike Boezen Mohammadhossein Somi Behrooz Z Alizadeh | 2020 | World Journal of Gastroenterology2020，26，38： | 5 |
| 12 | 累积叠轧焊多层铜基复合材料的强度预测显示文摘评价用累积叠轧焊(ARB)制备纳米结构Cu/Al/Ag多层复合材料的可行性,分析该复合材料的拉伸性能和电导率。利用强化机制和从X射线衍射获取的结构参数建立理论模型预测复合材料的抗拉强度。结果表明,随着ARB的进行,实验和计算得到的抗拉强度均有所提高,在第5个ARB循环时达到最大值,分别为450 MPa和510 MPa。在初始ARB循环后,电导率略有下降;随着ARB循环次数的继续增加,电导率的下降幅度增大。总之,用ARB制备这类多层纳米复合材料具有优势,所建立的模型可准确预测材料的抗拉强度。 | P.SEIFOLLAHZADEH Morteza ALIZADEH M.R.ABBASI | 2021 | Transactions of Nonferrous Metals Society of China2021，31，6： | 5 |
| 13 | Prevalence of hepatitis C virus infection and its related risk factors in drug abuser prisoners in Hamedan-Iran显示文摘AIM: Recent studies in Iran has shown that prevalence of hepatitis C virus (HCV) infection among Iranian prisoners is high, in spite of low HCV seroprevalence in general population.METHODS: This study was carried out in the central prison of Hamedan - Iran, in year 2002. Inmates were interviewed using a standard questionnaire including demographic,imprisonment history and HCV-related risk behaviors items. Thereafter, the sera drawn from the participants were tested for anti-HIV and anti-HCV antibodies.RESULTS: A total number of 427 drug abuser inmates participated in our study. Three hundred and ninety-seven (93%) were men and 30 (7%) were women. Total number of Ⅳ drug abusers (IDA) and non-Ⅳ drug abusers (NIDA)was 149 (34.9%) and 278 (65.1%), respectively. The overall rate of antibody positivity among inmates was 0.9% for HIV and 30% for HCV. Of all IDAs, 31.5% and of NIDAs, 29.1% had serological evidence of HCV infection.CONCLUSION: The seroprevalence of HCV infection among drug abuser prisoners in comparison with the general population in Iran, is very high (30% vs in italics 0.2%).Our results indicate the importance of policies to prevent transmission of HCV infection during and following incarceration. | Amir Houshang Mohammad Alizadeh Seyed Moayed Alavian Khalil Jafari Nastaran Yazdi | 2005 | World Journal of Gastroenterology2005，11，26： | 5 |
| 14 | Hot Extrusion Process Effect on Mechanical Behavior of Stir Cast Al Based Composites Reinforced with Mechanically Milled B_4C Nanoparticles显示文摘In this study, aluminum alloy (Al-2 wt% Cu) matrix composites reinforced with 1, 2 and 4 wt% boron carbide nanoparticles fabricated through mechanical milling with average size of 100 nm were fabricated via stir casting method at 850℃. Cast ingots of the matrix alloy and the composites were extruded at 500℃ at an extrusion ratio of 10:1 to investigate the effects of hot extrusion on the mechanical properties of the composites. The microstructures of the as-cast and the extruded composites were investigated by scanning electron microscopy (SEM). Density measurement, hardness and tensile tests were carried out to identify the mechanical properties of the composites. The extruded samples revealed a more uniform distribution of B4C nanoparticles. Also, the extruded samples had strength and ductility values superior to those of the as-cast counterparts. In the as-cast and the extruded samples, with increasing amount of B4C nanoparticles, yield strength and tensile strength increased but elongation to fracture decreased. | A. Alizadeh E. Taheri-Nassaj M. Hajizamani | 2011 | Journal of Materials Science & Technology2011，27，12： | 5 |
| 15 | AN IMPRINTED POLYMER FOR REMOVAL OF Cd^(2+) FROM WATER SAMPLES:OPTIMIZATION OF ADSORPTION AND RECOVERY STEPS BY EXPERIMENTAL DESIGN显示文摘新印离子的聚合物(IIP ) 被 4-vinylpyridine (单体) 的 copolymerization 综合, ethyleneglycoldimethacrylate (cross-linker ) 和 2,2-azobis-isobutyronitrile (开始者) 面对 Cd2+ 和 quinaldic 酸(complexing 代理人) 。IIP 和空白的聚合物的吸附能力分别地是 45.0 和 6.2 mg g1,这被发现。为不同二进制混合的印的聚合物的相对选择系数也是计算的。比作非印的聚合物(捏) , IIP 为 Cd (II ) 有更高的选择。IIP 被使用一个简单的批抽取过程从水样品为镉抽取用作吸着剂。从 IIP 的 Cd2+ 抽取和它的恢复上的不同参数的效果被使用试验性的设计方法论评估并且优化。优化吸附 / 解吸附作用过程被申请从真实的水样品的镉移动。获得的恢复证明这 IIP 能从水样品被用于踪迹镉离子的移动。 | Taher Alizadeh | 2011 | Chinese Journal of Polymer Science2011，29，6： | 4 |
| 16 | Thermodynamic study and methanothermal temperature-programmed reaction synthesis of molybdenum carbide显示文摘Nanostructured molybdenum carbide(Mo_2C) was successfully prepared from molybdenum trioxide(MoO _3) using methanothermal temperature-programmed reaction. Thermodynamic analysis indicated that in presence of methane, the formation of Mo_2 C from MoO _3 occurs through the path of MoO _3 → MoO _2 → Mo_2 C. The carburized MoO _3 was characterized using X-ray diffraction(XRD), CHNS/O analysis, Brunauer–Emmett–Teller(BET) analysis, and field-emission scanning electron microscopy(FESEM). At final carburization temperatures of 700 and 800°C and at methane contents ranging from 5vol% to 20vol%, Mo_2 C was the only solid product observed in the XRD patterns. The results indicated that the effect of methane content on the formation of the carbide phase is substantial compared with the effect of carburization time. Elemental analysis showed that at a final temperature of 700°C, the carbon content of carburized MoO _3 is very close to the theoretical carbon mass percentage in Mo_2 C. At higher carburization temperatures, excess carbon was deposited onto the surface of Mo_2 C. High-surface-area Mo_2 C was obtained at extremely low heating rates; this high-surface-area material is a potential electrocatalyst. | Parham Roohi Reza Alizadeh Esmaeil Fatehifar | 2016 | International Journal of Minerals,Metallurgy and Materials2016，23，3： | 4 |
| 17 | A controllable hydrothermal method to prepare La(OH)_3 nanorods using new precursors显示文摘Using the hydrothermal method, lanthanum hydroxide nanorods were synthesized by the reaction of La Cl3·7H2O, ethylenediamine, and hydrazine. According to SEM results, ethylenediamine and hydrazine with p H management could control the particle growth and played an important role in formation of lanthanum hydroxide nanorods. The morphology and microstructure of the obtained products were characterized by X-ray diffraction(XRD) spectra, energy-dispersive X-ray spectroscopy(EDX), Fourier transformed infrared(FTIR) spectrum, transmission electron microscopy(TEM), and scanning electron microscopy(SEM). Furthermore, the effects of the molar ratio of the precursors as well as the reaction temperature and time on the morphology and particle size of the products were investigated. | Mehdi Mousavi-Kamazani Sakineh Alizadeh Fateme Ansari Masoud Salavati-Niasari | 2015 | Journal of Rare Earths2015，33，4： | 4 |
| 18 | A multiscale spatio-temporal framework to regionalize annual precipitation using k-means and self-organizing map technique显示文摘Determination of homogenous precipitation-based regions is a very important task in effective management of water resources. The present study tried to propose an effective precipitation-based regionalization methodology by conjugating both temporal pre-processing and spatial clustering approaches in a way to take advantage of multiscale properties of precipitation time series. Annual precipitation data of 51 years(1960-2010) for 31 rain gauges(RGs) were collected and used in proposed clustering approaches. Discreet wavelet transform(DWT) was used to capture the time-frequency attributes of the time series and multiscale regionalization was performed by using k-means and Self Organizing Maps(SOM) clustering techniques. Daubechies function(db) was selected as mother wavelet to decompose the precipitation time series. Also, proper boundary extensions and decomposition level were applied. Different combinations of the approximation(A) and detail(D) coefficients were used to determine the input dataset as a basis of spatial clustering. The proposed model's efficiency in spatial clustering stage was verified using three different indexes namely, Silhouette Coefficient(SC), Dunn index and Davis Bouldin index(DB). Results approved superior performance of k-means technique in comparison to SOM. It was also deduced that DWT-based regionalization methodology showed improvements in comparison to historical-based models. Cross mutual information was used to investigate the RGs of cluster 3's homogeneousness in DWT-k-means approach. Results of non-linear correlation approach verified homogeneity of cluster 3. Verifications based on mean annual precipitation values of rain gauges in each cluster also approved the capability of multiscale approach in precipitation regionalization. | Kiyoumars ROUSHANGAR Farhad ALIZADEH | 2018 | Journal of Mountain Science2018，15，7： | 4 |
| 19 | Bioactive Materials:A Comprehensive Review on Interactions with Biological Microenvironment Based on the Immune Response显示文摘Application of“bioactive materials”,as a modified version of biomaterials,can optimize the response of the biological system due to their surface reactivity and formation of strong interactions with the adjacent tissue upon implantation.However,choosing an appropriate bioactive material that suits to the application and provides the desired mechanical,physical,chemical and biological functionality,as well as understanding the aspects of biological reaction to the biomaterial,in particular immune response,it plays a key role in successful integration of the implant.In this review,we will discuss different bioactive materials including bioactive ceramics,polymers and composites and their applications in drug delivery and scaffold preparation in order to provide an adequate introduction to the recent studies.Considering the necessity of regulation of implant fate for higher biocompatibility,the comprehensive overview to the immune response will be reviewed with the focus on representing the cell-biomaterial interactions and more importantly,the inflammatory responses.Ultimately,we will also discuss about different approaches namely as immunomodulation to elicit the desired physiochemical properties and mimicking native cellular response using bioactive compounds,functionalizing the implant surface with active molecules and alteration of the surface morphology.With better understanding of bioactive materials and their interactions with body,more novel biomaterials representing desired properties can be designed. | Shirin Nour Nafiseh Baheiraei Rana Imam Navid Rabiee Mohammad Khodaei Akram Alizadeh Seyed Mohammad Moazzeni | 2019 | Journal of Bionic Engineering2019，16，4： | 4 |
| 20 | Distinct element modelling of fracture plan control in continuum and jointed rock mass in presplitting method of surface mining显示文摘Controlled blasting techniques are used to control overbreak and to aid in the stability of the remaining rock formation. Presplitting is one of the most common methods which is used in many open pit mining and surface blast design. The purpose of presplitting is to form a fracture plane across which the radial cracks from the production blast cannot travel. The purpose of this study is to investigate of effect of presplitting on the generation of a smooth wall in continuum and jointed rock mass. The 2D distinct element code was used to simulate the presplitting in a rock slope. The blast load history as a function of time was applied to the inner wall of each blasthole. Important parameters that were considered in the analysis were stress tensor and fracturing pattern. The blast loading magnitude and blasthole spacing and jointing pattern were found to be very significant in the final results. | Sharafisafa Mansour Aliabadian Zeinab Alizadeh Rezvan Mortazavi Ali | 2014 | International Journal of Mining Science and Technology2014，24，6： | 4 |
您所在的机构暂未开通此部分的功能，请联系管理员