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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Actual evapotranspiration and dual crop coefficients for dry-seeded rice and hybrid maize grown with overhead sprinkler irrigation显示文摘 | Alberto M C R Quilty J R Buresh R J | 2014 | Agricultural Water Management2014，136，： | 1 |
| 3 | Importance of staging of breast cancer and role of contrast ultrasound显示文摘 | Giorgio R Alberto M Roberta C | 2001 | Eur Radio2001，11，3： | 1 |
| 4 | Effect of gallic acid and catechin on lactobacillus hilgardii 5w growth and metabolism of organic compounds显示文摘 | ALBERTO M R FARIAS M E MANCA M C | 2001 | Journal of Agriculture and Food Chemistry2001，49，9： | 1 |
| 5 | Intracerebral VEGF injection highly upregulates AQP4 mRNA and protein in the perivascular space and glia limitans externa 显示文摘 | Inmaculada R Alberto M Josefina C | 2008 | Neurochemistry International2008，52，45： | 1 |
| 6 | Antioxidant capacities,carotenoids and polyphenols evaluation of fresh and refrigerated peach and nectarine cultivars from Italy显示文摘 | Claudio D V Giulia G Luigi M Annunziata C Alberto R | | 0，，： | 1 |
| 7 | Comparisons of energy balance and evapotranspiration between flooded and aerobic rice fields in the Philippines显示文摘 | Alberto M C R Wassmann R Hirano T | 2011 | Agric Water Manage2011，98，9： | 1 |
| 8 | A small fraction of dermatan sulfate with significantly increased anticoagulant activity was selected by interaction with the first complement protein显示文摘 | CALABRESE G C ALBERTO M F TUBIO R | 2004 | Thromb Res2004，113，： | 1 |
| 9 | CO2/heat fluxes in rice fields: Comparative assessment of flooded and non-flooded fields in the Philippines 显示文摘 | ALBERTO M C R WASSMANN R HIRANO T et el | 2009 | Agricultural and Forest Meteorology2009，149，： | 1 |
| 10 | A comparative survey of two analytical methods for identification and quantification ofhiogenie amines显示文摘 | Alberto M R Arena M E Manea De Nadra M C | 2002 | Food Control2002，13，2： | 1 |
| 11 | Antibacterial effect of phenolic compounds from different wines 显示文摘 | Rodrlguez Vaquero M Alberto M R Mancade Nadra M C | 2007 | Food Control2007，18，： | 1 |
| 12 | Influence of bioparticle size on the degradation of partially soluble wastewater in an anaerobic sequencing batch biofilm reactor (ASBBR) with mechanical stirring显示文摘 | Samantha C P Suzana M R Jose Alberto D R | 2005 | Bioresource Technology2005，96，6： | 1 |
| 13 | The influence of increasing carbon dioxide and temperature on competitive interactions between a C-3 crop, rice (Oryza sativa) and a C-4 weed (Echinochloa glabrescens)显示文摘 | Alberto A M P Ziska L H Cervancia C R | 1996 | Australian Journal of Plant Physiology1996，23，6： | 1 |
| 14 | A comparative survey of two analytical methods for identification and quantification of biogenic amines 显示文摘 | Alberto M R Arena M E Manca de Nadra M C | 2002 | Food contral2002，13，： | 1 |
| 15 | Radiation filed modeling in photoreactors-I, homogeneous media 显示文摘 | Orlando M A Roberto L R Alberto E C | 1986 | Chemical Engineering Science1986，41，3： | 1 |
| 16 | The influence of increasing carbon dioxide and temperature on competitive interactions between a C3 crop, rice (oryza sativa) and a C4 weed (echinochloa glabrescens) 显示文摘 | ALBERTO A M P ZISKA L H CERVANCIA C R | 1996 | Aust J Plant Physiol1996，23，： | 1 |
| 17 | Inhibition of cyclooxygenase activity by standardized hydroalcoholic extracts of four Asteraceae species from the Argentine Puna显示文摘 | Alberto M R Zampini I C Isla M I | 2009 | Braz J Med Biol Res2009，42，9： | 1 |
| 18 | Chemical kinetics of biomass pyrolysis显示文摘 | ELISEO R ALBERTO C TIZIANO F ALESSIO F GABRIELE M SAURO P SAMUELE S | 2008 | Energy Fuels2008，22，6： | 1 |
| 19 | A comparative survey of two analytical methods for identification and quantification of biogenic amines 显示文摘 | Alberto M R Arena M E Manca de Nadra M C | 2002 | Food Control2002，13，2： | 1 |
| 20 | Atomistic simulations on mullite Al2(Al2+2XSi2-2X)O10-X in a variable range of composition显示文摘 | DANIELE M SILVIA R ALBERTO C | 2008 | J Eur Ceram Soc2008，28，2： | 1 |
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