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| 1 | 氧化应激与疾病显示文摘饲料对动物的作用之一就是通过各组分的氧化提供代谢能,为在细胞线粒体中有效产生能量,每种动物均需要氧气。但氧是一种诱变气体,具有毒性,细胞的过量氧化,会导致系列非传染性病或恶化传染性病。因动物已建立了各种抗氧化体系,且饲料也是重要的抗氧化剂来源,故动物可生活在氧气环境中。因此在饲料与宿主之间还需调控氧化应激。 | Clifford AAdams 武书庚(编译) 齐广海(审校) 李海涛(审校) | 2009 | 饲料与畜牧(新饲料)2009,,3: | 3 |
| 2 | Efficacy and safety of self-expandable metal stents for biliary decompression in patients receiving neoadjuvant therapy for pancreatic cancer: a prospective study显示文摘 | A. Aziz Aadam Douglas B. Evans Abdul Khan Young Oh Kulwinder Dua | 2012 | Gastrointestinal Endoscopy2012,,1: | 2 |
| 3 | Serum-circulating His-tRNA synthetase inhibits organ-targeted immune responses显示文摘His-tRNA synthetase (HARS) is targeted by autoantibodies in chronic and acute inflammatory anti-Jo-1-positive antisynthetase syndrome. The extensive activation and migration of immune cells into lung and muscle are associated with interstitial lung disease, myositis, and morbidity. It is unknown whether the sequestration of HARS is an epiphenomenon or plays a causal role in the disease. Here, we show that HARS circulates in healthy individuals, but it is largely undetectable in the serum of anti-Jo-1-positive antisynthetase syndrome patients. In cultured primary human skeletal muscle myoblasts (HSkMC), HARS is released in increasing amounts during their differentiation into myotubes. We further show that HARS regulates immune cell engagement and inhibits CD4+ and CD8+ T-cell activation. In mouse and rodent models of acute inflammatory diseases, HARS administration downregulates immune activation. In contrast, neutralization of extracellular HARS by high-titer antibody responses during tissue injury increases susceptibility to immune attack, similar to what is seen in humans with anti-Jo-1-positive disease. Collectively, these data suggest that extracellular HARS is homeostatic in normal subjects, and its sequestration contributes to the morbidity of the anti-Jo-1-positive antisynthetase syndrome. | Ryan AAdams Cátia Fernandes-Cerqueira Antonella Notarnicola Elisabeth Mertsching Zhiwen Xu Wing-Sze Lo Kathleen Ogilvie Kyle PChiang Jeanette Ampudia Sanna Rosengren Andrea Cubitt David JKing John DMendlein Xiang-Lei Yang Leslie ANangle Ingrid ELundberg Per-Johan Jakobsson Paul Schimmel | 2021 | Cellular & Molecular Immunology2021,18,6: | 2 |
| 4 | Diffuse ax- onal injury Inon - missile head injury 显示文摘 | Aadam JH Graham DI Gennare TA | 1991 | J Neurol Neurosurg Psychaitr1991,54,: | 1 |
| 5 | Manufacture of adhesive joints and bulk specimens with high - temperature adhesives 显示文摘 | R D AADAMS M GIBBS | 2004 | Intematlonal Journal of Adhesion and Adhesives2004,24,1: | 1 |
| 6 | Gas pulsation reduction in a multicylinder compressor suction manifold using valve-to-valve mass flow rate phase shift显示文摘 | PARK J I BILAL N AADAMS D E | | 0,,04: | 1 |
| 7 | Selfrated health and employment status in chronic haemodialysis patients显示文摘 | Molsted S Aadam M Schou I | 2004 | Scandinavian Journal of Urology Nephrology2004,38,2: | 1 |
| 8 | Manufacture of Adhesive Joints and Bulks Specimens with High-Temperature Adhesives显示文摘 | AADAMS R D GIBBS M | 2004 | International Journal of Adhesion and Adhesives2004,24,1: | 1 |
| 9 | Gas Pulsation Re- ductions in a Multicylinder Compressor Suction Manifold Using Valve-to-valve Mass Flow Rate Phase Shifts显示文摘 | Park J I Bilal N Aadams D E | 2007 | Journal of Vibration and Acous- tics2007,129,4: | 1 |
| 10 | Dioxiranes: a new class of powe oxidants显示文摘 | AAdam W Curci R Edwards J O | 1989 | Account of Chemical Research1989,,22: | 1 |
| 11 | W-Sb-Au mineralization at Woxi deposit in western Hunan, China 显示文摘 | Peng Bo Piestrzynski Aadam | 1999 | Mineralogia Polonica1999,30,1: | 1 |
| 12 | Characterizing bubble interaction effects in synchronous-double-pulse laser ablation for enhanced nanoparticle synthesis显示文摘To further advance nanomaterial applications and reduce waste production during synthesis,greener and sustainable production methods are necessary.Pulsed laser ablation in liquid(PLAL)is a green technique that enables the synthesis of nanoparticles.This study uses synchronous-double-pulse PLAL to understand bubble interaction effects on the nanoparticle size.By adjusting the lateral separation of the pulses relative to the maximum bubble size,an inter-pulse separation is identified where the nanoparticle size is fourfold.The cavitation bubble pair interaction is recorded using a unique coaxial diffuse shadowgraphy system.This system allows us to record the bubble pair interaction from the top and side,enabling the identification of the bubble’s morphology,lifetime,volumetric,and displacement velocity.It is found that the collision and collapse of the bubbles generated at a certain inter-pulse separation results in a larger nanoparticle size.These results mark a significant advancement by controlling the abundance of larger nanoparticles in PLAL,where previous efforts were primarily focused on reducing the average nanoparticle size.The experimentally observed trends are confirmed by numerical simulations with high spatial and temporal resolution.This study serves as a starting point to bridge the gap between upscaled multi-bubble practices and fundamental knowledge concerning the determinants that define the final nanoparticle size. | FARBOD RIAHI ALEXANDER BUßMANN CARLOS DONATE-BUENDIA STEFAN ADAMI NICOLAUS AADAMS STEPHAN BARCIKOWSKI BILAL GOKCE | 2023 | Photonics Research2023,11,12: | 0 |