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| 1 | 原位肝移植术后感染及其预防显示文摘原位肝移植(OLT)作为治疗器官终末期功能障碍的手段已被全世界广泛采用。随着联合免疫抑制剂的运用,特别是自从使用环孢霉素A后,排斥反应的发生率大大降低,严重感染的发病率和死亡率却因此而提高到了显著位置。严重感染的最危险时期是OLT术后早期阶段,此外,除了脾窦产生的巨噬细胞以外,主要以肝脏的Kupffer细胞为代表的网状内皮细胞功能常仍受到限制。本组病例。 | Th.Bein H.Forst A.Winkelmann M.Haller J.Briegel K.Unertl J.Groh E.Pratschke G.Ruckdeschel 魏来 | 1998 | 德国医学1998，15，1： | 5 |
| 2 | Single capillary oximetry and tissue ultrastructural sensing by dual-band dual-scan inverse spectroscopic optical coherence tomography显示文摘Measuring capillary oxygenation and the surrounding ultrastructure can allow one to monitor a microvascular niche and better understand crucial biological mechanisms.However,capillary oximetry and pericapillary ultrastructure are challenging to measure in vivo.Here we demonstrate a novel optical imaging system,dual-band dual-scan inverse spectroscopic optical coherence tomography(D2-ISOCT),that,for the first time,can simultaneously obtain the following metrics in vivo using endogenous contrast:(1)capillary-level oxygen saturation and arteriolar-level blood flow rates,oxygen delivery rates,and oxygen metabolic rates;(2)spatial characteristics of tissue structures at length scales down to 30 nm;and(3)morphological images up to 2mm in depth.To illustrate the capabilities of D2-ISOCT,we monitored alterations to capillaries and the surrounding pericapillary tissue(tissue between the capillaries)in the healing response of a mouse ear wound model.The obtained microvascular and ultrastructural metrics corroborated well with each other,showing the promise of D2-ISOCT for becoming a powerful new non-invasive imaging tool. | Rongrong Liu James A.Winkelmann Graham Spicer Yunxiao Zhu Aya Eid Guillermo A.Ameer Vadim Backman Ji Yi | 2018 | Light(Science & Applications)2018，7，1： | 4 |
| 3 | Scanning electron microscope as a flexible tool for investigating the properties of UV-emitting nitride semiconductor thin films显示文摘In this paper we describe the scanning electron microscopy techniques of electron backscatter diffraction, electron channeling contrast imaging, wavelength dispersive X-ray spectroscopy, and cathodoluminescence hyperspectral imaging. We present our recent results on the use of these non-destructive techniques to obtain information on the topography, crystal misorientation, defect distributions, composition, doping, and light emission from a range of UV-emitting nitride semiconductor structures. We aim to illustrate the developing capability of each of these techniques for understanding the properties of UV-emitting nitride semiconductors, and the benefits were appropriate, in combining the techniques. | C.Trager-Cowan A.Alasmari W.Avis J.Bruckbauer P.R.Edwards B.Hourahine S.Kraeusel G.Kusch R.Johnston G.Naresh-Kumar R.W.Martin M.Nouf-Allehiani E.Pascal L.Spasevski D.Thomson S.Vespucci P.J.Parbrook M.D.Smith J.Enslin F.Mehnke M.Kneissl C.Kuhn T.Wernicke S.Hagedorn A.Knauer V.Kueller S.Walde M.Weyers P.-M.Coulon P.A.Shields Y.Zhang L.Jiu Y.Gong R.M.Smith T.Wang A.Winkelmann | 2019 | Photonics Research2019，7，11： | 0 |
| 4 | Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging显示文摘Optical coherence tomography angiography relies on motion for contrast and requires at least two data acquisitions per pointwise scanning location.We present a method termed spectral contrast optical coherence tomography angiography using visible light that relies on the spectral signatures of blood for angiography from a single scan using endogenous contrast.We demonstrate the molecular sensitivity of this method,which enables lymphatic vessel,blood,and tissue discrimination. | James A.Winkelmann Aya Eid Graham Spicer Luay M.Almassalha The-Quyen Nguyen Vadim Backman | 2019 | Light(Science & Applications)2019，8，1： | 0 |
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