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| 1 | 冠心病患者的房室瓣环运动异常显示文摘目的:评价冠心病患者左房室瓣环运动的改变。方法:用M型超声心动图记录177例胸痛患者(冠心病组123例,对照组54例)的左房室瓣环运动曲线,测量:①房室瓣环平面纵向移动的总振幅(AVPDt)、舒张早期上移幅度(AVPDe)和心房收缩期上移幅度(AVPDa);②AVP-Da/AVPDt及AVPDa/AVPDe的比值;③从心电图Q波至左室长轴开始缩短以及Q波至长轴缩至最短时的时距;④收缩期缩短速率(Shortrate)及舒张早期伸长速率(Lengthrate)。结果:与对照组相比,冠心病组AVPDt、AVPDe、Lengthrate及室间隔侧的Shortrate均显著降低(P<0.01)。校正年龄和性别因素后,冠心病组室间隔侧的AVPDt及Shortrate仍显著降低(P<0.05)。结论:用超声心动图测定房室瓣环运动能检出冠心病患者休息时即可存在的左室功能异常。 | 施仲伟 P.Aylward A.Russell R.Minson | 1998 | 中国医学影像技术1998，14，6： | 3 |
| 2 | Patient-derived orthotopic xenograft models for cancer of unknown primary precisely distinguish chemotherapy,and tumor-targeting S.typhimurium A1-R is superior to first-line chemotherapy显示文摘Cancer of unknown primary(CUP)is a recalcitrant disease with poor prognosis because it lacks standard first-line therapy.CUP consists of diverse malignancy groups,making personalized precision therapy essential.The present study aimed to identify an effective therapy for a CUP patient using a patient-derived orthotopic xenograft(PDOX)model.This paper reports the usefulness of the PDOX model to precisely identify effective and ineffective chemotherapy and to compare the efficacy of S.typhimurium A1-R with first-line chemotherapy using the CUP PDOX model.The present study is the first to use a CUP PDOX model,which was able to precisely distinguish the chemotherapeutic course.We found that a carboplatinum(CAR)-based regimen was effective for this CUP patient.We also demonstrated that S.typhimurium A1-R was more effective against the CUP tumor than first-line chemotherapy.Our results indicate that S.typhimurium A1-R has clinical potential for CUP,a resistant disease that requires effective therapy. | Kentaro Miyake Tasuku Kiyuna Masuyo Miyake Kei Kawaguchi Sang Nam Yoon Zhiying Zhang Kentaro Igarashi Sahar Razmjooei Sintawat Wangsiricharoen Takashi Murakami Yunfeng Li Scott D.Nelson Tara A.Russell Arun S.Singh Yukihiko Hiroshima Masashi Momiyama Ryusei Matsuyama Takashi Chishima Shree Ram Singh Itaru Endo Fritz C.Eilber Robert M.Hoffman | 2018 | Signal Transduction and Targeted Therapy2018，3，1： | 2 |
| 3 | American Cancer Society Guidelines for Breast Screening with MRI as an Adjunct to Mammography显示文摘 | DebbieSaslow CarlaBoetes WylieBurke StevenHarms Martin O.Leach Constance D.Lehman ElizabethMorris EttaPisano MitchellSchnall StephenSener Robert A.Smith EllenWarner MartinYaffe Kimberly S.Andrews Christy A.Russell | 2009 | CA: A Cancer Journal for Clinicians2009，，： | 1 |
| 4 | Determination of lead in vinegar by ICP-MS and GFAAS: evaluation of different sample preparation procedures显示文摘 | Kuria Ndung’u Sharon Hibdon A.Russell Flegal | 2004 | Talanta2004，，1： | 1 |
| 5 | Approach-Avoidance and Affiliation as Functions of the Emotion-Eliciting Quality of an Environment显示文摘 | James A.Russell Albert Mehrabian | | 0，，03： | 1 |
| 6 | 生物圈中的铅:最近的趋势显示文摘对某些含铅产品(如汽油添加剂、油漆、焊料)的规定降低了铅在环境中的释放。这反映在城市和偏远地区悬浮微粒和微粒沉降物中铅浓度的降低。最近美国和欧洲几个国家平均血铅(PbB)水平的减少也很明显。然而,和估计的人类自然PbB水平(0.016μg/dL或 0.8n mol/L)相比,这些下降是很小的。由于全球范围内环境接触源的增加(如粮食、水、土壤、尘埃),进一步的减少将更难达到。此外,尽管在铅使用和排放方式上有地区性变化,过去10年的趋势表明,国内(美国)、国际铅的消耗没有下降。为了进一步减少全球性的铅毒害,制定对国际上铅的使用和排放的控制计划是必要的。 | Donald R.Smith A.Russell Flegal 段霞瑜 | 1995 | 人类环境杂志1995，24，1： | 1 |
| 7 | Application of laser energy deposition to improve performance for high speed intakes显示文摘Research interest has been growing in recent years in supersonic transport,particularly supersonic propulsion systems.A key component of a commonly studied propulsion system,ramjets,is the air intake.For supersonic propulsion systems a major factor in the overall efficiency is the intake pressure recovery.This refers to the ratio of the average total pressure after the intake to that of the freestream.One phenomenon that can have a large effect on this performance index is flow separation at the inlet.The aim of this work is to examine how pulsed laser energy deposition can be used to improve pressure recovery performance by reducing flow separation at the inlet.This research examines the effects of pulsed laser energy deposition upstream of an intake with an axisymmetric centrebody in a Mach 1.92 indraft wind tunnel.Laser frequency was varied between 1 and 60 kHz with an energy per pulse of 5.6 mJ.Schlieren photography was used to examine the fundamental fluid dynamics while total and static pressure downstream of the intake diffuser were measured to examine the resulting effect on the performance.Schlieren imaging shows that the interaction between the laser generated thermal bubble and the leading edge shock produced by the centrebody results in a significant reduction in separation along the intake cone.Analysis of the schlieren results and the pressure results in tandem illustrate that the average separation location along the length of the centrebody directly correlates to the pressure recovery observed in the intake.At the optimal laser frequency,found for this Mach number to be 10 kHz,the pressure recovery is found to increase by up to 4.7%.When the laser power added to the system is considered,this results in an overall increase in propulsive power of 2.47%. | A.Russell M.Myokan H.Bottini A.Sasoh H.Zare-Behtash K.Kontis | 2020 | Propulsion and Power Research2020，9，1： | 0 |
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