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826篇 您的检索式:期刊名="PHARMACOLOGICAL RESEARCH"
    题名 作者 年代 出处 被引量
1Involvement of JAK/STAT signaling in the pathogenesis of inflammatory bowel disease显示文摘Mehmet Coskun Mohammad Salem Jannie Pedersen Ole Haagen Nielsen 2013Pharmacological Research2013,,:3
2Proton pump inhibitors in GORD显示文摘Vincenzo Savarino Francesco Di Mario Carmelo Scarpignato 2008Pharmacological Research2008,,3:3
3The immune system and cardiac repair显示文摘Nikolaos G. Frangogiannis 2008Pharmacological Research2008,,2:3
4Asymmetric dimethylarginine (ADMA) as a prospective marker of cardiovascular disease and mortality—An update on patient populations with a wide range of cardiovascular risk显示文摘Rainer H. B?ger Renke Maas Friedrich Schulze Edzard Schwedhelm 2009Pharmacological Research2009,,6:2
5Chitosan oligosaccharide as potential therapy of inflammatory bowel disease: Therapeutic efficacy and possible mechanisms of action显示文摘Mohammad Yousef Rath Pichyangkura Sunhapas Soodvilai Varanuj Chatsudthipong Chatchai Muanprasat 2012Pharmacological Research2012,,1:2
6Ageing and gut microbes: Perspectives for health maintenance and longevity显示文摘Elena Biagi Marco Candela Silvia Turroni Paolo Garagnani Claudio Franceschi Patrizia Brigidi 2012Pharmacological Research2012,,:2
7Carotenoids and human health显示文摘A.V. Rao L.G. Rao 2007Pharmacological Research2007,,3:2
8Clinical research progress of oral administration of traditional Chinese medicine in the treatment of dry eyes显示文摘Dry eye is a common and frequently occurring ophthalmology disease with complex etiology and easy recurrence.Oral administration of traditional Chinese medicine has the characteristicsof high curative effect and little toxic and side effect in the treatment of dry eye.This paper collates the domestic reported clinical studies on the oral administration of traditional Chinese medicine in the treatment of dry eye,which are discussed from four aspects:special prescription for specific disease,addition and subtraction of main prescription,treatment based on syndrome differentiation and proprietary Chinese medicine.The curative effect and advantages of traditional Chinese medicine in the treatment of dry eye are demonstrated,providing a reference for the treatment of dry eye in the future.Jin-Xiang Mao Yi-Hua Fan Hao Lin Li Liu Jia-Yu Huang Xu Wang Xin-Ju Li 2021TMR Pharmacology Research2021,1,3:2
9The effect of Modified Wen-Dan decoction on hippocampal astrocytes in depression model rats显示文摘Background:This study aimed to observe the effect of Modified Wen-Dan decoction on hippocampal astrocytes in depression model rats.Methods:A total of 48 rats were randomly divided into a control group,a model group,a Modified Wen-Dan decoction group(referred toas the traditional Chinese medicine group),and a fluoxetine control group(referred to as the Western medicine group).The control group was provided with a free diet and without any stimulation,while the remaining three groups were solitarily housed incombination with chronic unpredictable mild stress stimuli to replicate the depression rat model.The rats were subjected to the open-field and sucrose preference experiments for behavioral observation,and q-PCR was used to detect the mRNA of specific markers of hippocampal astrocytes,glial fibrillary acidic protein,and S100 calcium-binding proteinβ(S100β)in each group.Immunohistochemistry was used to observe the protein expression of glial fibrillary acidic protein and S100βin thehippocampus of rats of each group.Results:The behavioral results showed that,compared with the control group,the rats in the model group showed a decrease in the score of the open-field experiment and in the rate of sucrose preference(P<0.05).The score of the open-field experiment and the rate of sucrose preference was increased in the Chinese and Western medicine groups(P<0.05),compared to that of the model group.No significant difference was found between the Chinese and Western medicine groups(P>0.05).The q-PCR results showed that the mRNA and protein expression levels of GFAP and S100βwere downregulated in the model group compared to that of the control group(P<0.05).Compared with the model group,the mRNA expression levels of glial fibrillary acidic proteinand S100βwere upregulated in the traditional Chinese medicine group as well as in the Western medicine group(P<0.05).No significant difference between the Chinese and Western medicine groups was found.Conclusion:The mechanism of the antidepressant effect of Modified Wen-Dan decoction may be related to the improvement of hippocampal astrocyte dysfunction in rats.Li-Ping Zhang Shen-jun Wang Ting Xue Lei Xu Yun-Sha Zhang Ying Chen Jun Yang Rui-Wen Song Xue-Yan Wang 2021TMR Pharmacology Research2021,1,3:2
10Hepatoprotective effects of 18beta-glycyrrhetinic acid on carbon tetrachloride-induced liver injury: inhibition of cytochrome P450 2E1 expression 显示文摘Jeong HG 2002Pharmacological Research2002,46,3:1
11The chemistry and biotransformation of tea constitu- ents 显示文摘Sang S M Joshua D L Ho C T 2011Pharmacological Research2011,64,:1
12Explanations of dose-dependent decline of diphenylhydantoin plasa levels by fitting to the intergrated form of the Michaelis-Menten equation显示文摘Gerber N Wagner J G 1972Research Communications in Chemical Pathology and Pharmacology1972,3,3:1
13Photodynamic activity of the haematoporphyrin derivative with rutin and arginine substituents HpD- Rut2- Arg2 against staphylococcus aureus and pseudomonas aeruginosa 显示文摘SZPAKOWSKA M LASOCKI K GRZYBOWSKI J 2001Pharmacological Research2001,44,3:1
14ISOLATED CARDIAC CELLS FOR ELECTROPHARMACOLOGICAL STUDIES显示文摘ELISABETTA CERBAI LAURA SARTIANI PETRA DE PAOLI ALESSANDRO MUGELLI 2000Pharmacological Research2000,,1:1
15Role of Moringa oleifera leaf extract in the regulation of thyroid hormone status in adult male and female rats显示文摘Tahiliani P Kar A 2000Pharmacological Research2000,41,3:1
16Urinary pharmacolduetics of betalains following comumption of red beet juice in healthy humans 显示文摘Thomas Frank Florian Conrad Slintzing Reinhold Carle 2005Pharmacological Research2005,52,:1
17P-glycoprotein inhibitors and their screening: a perspective from bioavailability enhancement显示文摘Manthena V.S Varma Yasvanth Ashokraj Chinmoy S Dey Ramesh Panchagnula 2003Pharmacological Research2003,,4:1
18Angiotensin II type 2 receptor-dependent increase in nitric oxide synthase activity in the endothelium of db/db mice is mediated via a MEK pathway 显示文摘TAGUCHI K MATSUMOTO T KAMATA K 2012Pharmacological Research2012,66,1:1
19Diabetic pe- ripheral neuropathy: Current perspective and tuture direc- tions显示文摘Randhir Singh Lalit Kishore Navpreet Kaur 2013Pharmacological Research2013,,:1
20The binding of BrnK IT2 on mammal and insect sodium channels by surface plasmon reso- nance assay 显示文摘Chai Z F Bai Z T Liu T 2006Pharmacological Research2006,54,2:1
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