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| 1 | 以大剂量或低剂量二磷酸氯喹作为新型冠状病毒肺炎住院患者辅助治疗的临床疗效显示文摘至今尚没有推荐用于新型冠状病毒肺炎(COVID-19)的特异性抗病毒药物。细胞研究表明,高浓度二磷酸氯喹(CQ)可发挥抗病毒作用。该研究评估了2种CQ剂量在重症COVID-19患者中的安全性和有效性,为平行、双盲、随机的Ⅱb期临床试验,收录81例COVID-19成年患者。试验基地为巴西亚马逊马瑙斯市的三级医疗机构。试验时间为2020年3月23日至4月5日。 | 胡骢(编译) Borba MGS Val FFA Sampaio VS | 2020 | 中华医学杂志2020，100，41： | 20 |
| 2 | 长期食用含糖和人工甜味剂的饮料与美国成年人死亡风险的关系显示文摘摄入含糖饮料(sugar-sweetened beverages,SSB)或含人工甜味剂饮料(artificially sweetened beverages,ASB)是否与死亡风险相关,这关乎公共卫生利益。研究者分析了卫生专业人员随访研究(1986-2014年)中男性37 716人和护士健康研究(1980-2014年)中女性80 647人(基线无慢性病)的SSB和ASB的消费与总死亡率和病因特异性死亡率之间的关系。应用Cox比例风险回归估计风险比和95%CI。结果显示,在随访3415564人年期间,研究者记录了36436例死亡,其中心血管病死亡7896例,癌症死亡12380例。 | 刘青(译) 叶鹏(摘、审校) Malik VS Li Y Pan A De Koning L Schernhammer E Willett WC Hu FB | 2019 | 中华高血压杂志2019，27，5： | 9 |
| 3 | Surgical considerations for ‘intrinsic' brainstem gliomas: proposal of a modification in classification显示文摘 | Mehta VS Chandra PS Singh PK Garg A Rath GK | 2009 | 中国神经肿瘤杂志2009，7，3： | 9 |
| 4 | 脑弓形体病18例临床与病理学研究显示文摘研究纽约地区18例脑弓形体病尸检材料,弓形体病仅见于脑部者9例。神经系统表现:(1)弥漫性脑病(14例);(2)局部性异常(12例);(3)脑膜刺激征(3例)。脑部病变为坏死伴炎症者12例。诊断以发现囊型民政弓形体和速殖子为依据。脑CT扫描,血清弓形体抗体体测定和病理学检查有助于诊断。 | Venk.,VS 刘德纯 | 1994 | 中华神经精神科杂志1994，27，5： | 8 |
| 5 | Investigation of tuberculosis clusters in Dehradun city of India显示文摘Objective:To investigate the presence of statistically significant geographical clusters of tuberculosis(TB) using Geographical Information System and spatial scan statistics in Dehradun, India.Methods:The spatial scan statistic implemented with a software program,SaTScan v6.1, was used to test the presence of statistically significant spatial clusters of TB and to identify their approximate locations(P<0.05 for primary clusters and P<0.1 for secondary clusters). Geographical Information System was used for geographical analysis.Results:Significant high rate spatial clusters were identified in seven wards of the Dehradun Municipal area. Conclusions:There is sufficient evidence about the existence of statistically significant TB clusters in seven wards of Dehradun,India.The purely spatial scan statistics methodology used in this study has a potential use in surveillance of TB for detecting the true clusters of the disease. | Neeraj Tiwari Vineeta Kandpal Ajoy Tewari K.Ram Mohan Rao Tolia VS | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，6： | 3 |
| 6 | 胰高血糖素基因克隆、表达及鉴定显示文摘目的 研制基因工程胰高血糖素,用于治疗因注射胰岛素或口服抗糖尿病药物而引起的严重低血 糖反应。方法 依据人胰高血糖素氨基酸组成序列,采用大肠杆菌出现频率高的氨基酸密码子,体外合成胰高血 糖素基因序列,克隆于pGEX-1N质粒,转化人BL21(DE3)菌中,对阳性克隆转化质粒进行DNA测序。用IPTG诱导 转化的胰高血糖素工程菌,产生谷胱苷肽转移酶的融合蛋白,经谷胱苷肽Sepharose4B亲和层析后,由 Factor Xa酶 进行柱上切割,最后用RP-HPLC得到纯化产物。产品用质谱法测相对分子质量,并对N末端15个氨基酸测序。 结果DNA测序显示克隆基因序列正确,产品相对分子质量为3486J末端15个氨基酸序列与理论值相同,产率为 1.9mg/L。结论 获得以可溶性融合蛋白方式表达的胰高血糖素基因工程菌,适于快速生产天然序列重组胰高血 糖素。 | 母敬郁 张桂荣 王峤 尚庆义 杨翰仪 Joni Lukwanize Wettai Ananthanarayanan VS | 2001 | 中国生物制品学杂志2001，14，2： | 2 |
| 7 | MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3显示文摘 | Joglekar MV Parekh VS Mehta s | | 0，，2： | 2 |
| 8 | Relationship between effective radiation dose and outcome of radioiodine therapy for thyroid cancer显示文摘 | Maxon HR Ⅲ Thomas SR Hertzberg VS | 1983 | N Engl J Med1983，309，： | 2 |
| 9 | Artifact reduction in true-FISP imaging of the coronary arteries by adjusting imaging frequency显示文摘 | Deshpande VS Shea SM Li D | 2003 | Magn Reson Med2003，49，5： | 2 |
| 10 | Neonatal pain response to beel stick vs venepuncture for routine blood sampling显示文摘 | Shah VS Taddio A Bennett S | 1997 | Arch Dis Child Fetal Neonatal Ed1997，77，： | 2 |
| 11 | Surgical use of breast ultrasound显示文摘 | Rubio IT Henry-Tillman R Klimberg VS | 2003 | Surg Clin North Am2003，83，： | 1 |
| 12 | Incidence and duration of recurrence of respiratory tuberculosis in adults 显示文摘 | Gavrilenko VS Tavolzhanskii VP Oksachenko OO Miller VA Kozlova MK Spevak Ⅳ | 1993 | Probl Tuberk1993，，2： | 1 |
| 13 | Fibrovascu lar ingrowth at sclerotomy sites in vitreetomized diabetic eyes with recurrent vitreous hemorrhage: ultrasound biomicroscopy findings 显示文摘 | Hershberger VS Augsburger J J Hutchins RK | 2004 | Ophthalmology2004，111，6： | 1 |
| 14 | The therapeutic use of botulinum toxin in cervical a Ad maxillofacial conditions:an evidence-based review显示文摘 | Ihde SK Konstantinovic VS | 2007 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod2007，104，2： | 1 |
| 15 | Early Amplatzer occluder closure of a postinfarct ventricular septal defect as a bridge to surgical procedure显示文摘 | Costache VS Chavanon O Bouvaist H | 2007 | Interact Cardiovasc Thorac Surg2007，，4： | 1 |
| 16 | Osteoclast function and its control显示文摘 | Pazianas M Shakar VS | 1993 | Exp Physiol1993，78，6： | 1 |
| 17 | Primate embryonic stem cells显示文摘 | Marshall VS | 1998 | Curr Top Dev Biol1998，38，： | 1 |
| 18 | A study of platelet aggregation, thromboxane A2 and prostacyclin in central aortic and coronary sinus blood in ischemic heart disease显示文摘 | Bhargava B Chandra N | 1994 | Indian Heart J1994，46，4： | 1 |
| 19 | 2-Chloroadenine and 2-chloroadenosine显示文摘 | Welliky VS | 1958 | J Org Chem1958，23，1： | 1 |
| 20 | Comparative evaluation of safety and efficacy of cefmetazole and cefoxitin in lower respiratory tract infections显示文摘 | Kenyon VS Halkias KD | 1989 | J Antimicrob Chemother1989，23，： | 1 |
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