|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Osteopontin as potential biomarker and therapeutic target in gastric and liver cancers显示文摘Gastric cancer and liver cancer are among the most common malignancies and the leading causes of death worldwide,due to late detection and high recurrence rates.Today,these cancers have a heavy socioeconomic burden,for which a full understanding of their pathophysiological features is warranted to search for promising biomarkers and therapeutic targets.Osteopontin (OPN) is overexpressed in most patients with gastric and liver cancers.Over the past decade,emerging evidence has revealed a correlation of OPN level and clinicopathological features and prognosis in gastric and liver cancers,indicating its potential as an independent prognostic indicator in such patients.Functional studies have verified the potential of OPN knockdown as a therapeutic approach in vitro and in vivo .Furthermore,OPN mediates multifaceted roles in the interaction between cancer cells and the tumor microenvironment,in which many details need further exploration.OPN signaling results in various functions,including prevention of apoptosis,modulation of angiogenesis,malfunction of tumor-associated macrophages,degradation of extracellular matrix,activation of phosphoinositide 3-kinase-Akt and nuclear factor-κB pathways,which lead to tumor formation and progression,particularly in gastric and liver cancers.This editorial aims to review recent findings on alteration in OPN expression and its clinicopathological associations with tumor progression,its potential as a therapeutic target,and putative mechanisms in gastric and liver cancers.Better understanding of the implications of OPN in tumorigenesis might facilitate development of therapeutic regimens to benefit patients with these deadly malignancies. | Dong-Xing Cao Zhi-Jie Li Xiao-Ou Jiang Yick Liang Lum Ester Khin Nikki P Lee Guo-Hao Wu John M Luk | 2012 | World Journal of Gastroenterology2012，18，30： | 29 |
| 2 | 甘草次酸靶向肝星状细胞治疗肝纤维化的体内研究显示文摘目的观察以6-磷酸甘露糖修饰的白蛋白(M6P26-HSA)作为特异性载体,将甘草次酸(GA) 靶向释放到肝星状细胞治疗肝纤维化的效果。方法用125I记由M6P26-HSA和GA在体外合成新的偶合物GA-HSA-M6P26,观察其在体内的器官分布情况,用双重免疫组织化学的方法观察星状细胞对GA- HSA-M6P26的选择性摄取;选用Sirius红染色观察GA-HSA-M6P26对肝纤维化时胶原沉积的影响,用定量聚合酶链反应检测GA-HSA-M6P26对Ⅰ型前胶原mRNA表达的影响。结果静脉注射后10min,GA-HSA- M6P26选择性地分布于肝脏,摄取高峰可达(5 5.093±5.404)%。双重免疫组织化学染色证实GA-HSA- M6P26主要被星状细胞选择性摄取,GA-HSA-M6P26治疗后肝脏胶原沉积明显减少,Ⅰ型前胶原和α-平滑肌肌动蛋白mRNA表达明显降低。结论GA-HSA-M6P26可以选择性地分布于肝脏星状细胞,有显著的抗肝纤维化作用。 | 张其胜 John M Luk 张健 田庚元 | 2005 | 中华肝脏病杂志2005，13，9： | 22 |
| 3 | Role of LPS/CD14/TLR4-mediated inflammation in necrotizing enterocolitis:Pathogenesis and therapeutic implications显示文摘AIM:To establish the roles of lipopolysaccharide (LPS)/CD14/toll-like receptor 4 (TLR4)-mediated inflammation in a rat model of human necrotizing enterocolitis (NEC).METHODS: Six pairs of intestinal samples from human NEC were collected before and after recovery for histological and molecular analysis of inflammatory cytokines and signaling components. In the rat NEC model, we isolated 10-cm jejunum segments and divided them into six groups (n=6) for sham operation, treatment with LPS, bowel distension, combined bowel distension and LPS stimulation, and two therapeutic groups. The potential eff icacy of a recombinant CD18 peptide and a monoclonal CD14 antibody was evaluated in the latter two groups. The serum and tissue levels of several inflammatory mediators were quantified by real-time polymerase chain reaction, ELISA and immunoblotting.RESULTS: Human acute phase NEC tissues displayed significant increases (P<0.05) in levels of TLR4, CD14, myeloid differentiation protein (MD)-2, tumor necrosis factor (TNF)-α and nuclear factor-κB when compared to those after recovery. The histological and inflammatory picture of human NEC was reproduced in rats that were treated with combined bowel distension and LPS, but not in the sham-operated and other control rats. Serum levels of interleukin-6 and TNF-α were also elevated. The NEC pathology was attenuated by treating the NEC rats with a monoclonal CD14 antibody or an LPS-neutralizing peptide.CONCLUSION:LPS and distension are required to produce the histological and inflammatory features of NEC. A potential treatment option is blocking LPS activation and leukocyte infi ltration. | Kwong L Chan Kwong F Wong John M Luk | 2009 | World Journal of Gastroenterology2009，15，38： | 17 |
| 4 | 超顺磁性氧化铁标记大鼠骨髓基质细胞经门静脉移植MRI活体示踪的研究显示文摘目的观察1.5T场强MRI联合动物专用线圈是否可以活体示踪经门静脉移植的纳米级超顺磁性氧化铁颗粒标记的骨髓基质细胞(bonemarrowstromalcellsBMSCs),为介入性门静脉骨髓基质细胞移植治疗终末期肝脏疾病的研究提供进一步的依据。方法供体大鼠5只,梯度密度离心分离BMSCs,纳米级超顺磁性氧化铁颗粒和脂质体转染BMSCs,体外经普鲁士蓝染色和HE染色确定细胞标记率。受体大鼠15只,分为5组,分别为对照组和纳米级超顺磁性氧化铁颗粒标记的骨髓基质细胞经门静脉移植入正常大鼠肝脏后2h、3d、7d及2周组。1.5T场强MRI联合动物专用线圈行T1W、T2W和T2序列扫描,观察肝脏信号改变情况,与对照组比较,并且与组织切片对照。结果纳米级超顺磁性氧化铁颗粒和脂质体转染BMSCs,细胞标记率>95%。经门静脉移植入正常大鼠肝脏后,T2序列扫描显示经标记的BMSCs在肝内显示弥漫性的结节性低信号影,移植后2h到2周均可见到细胞在受体肝脏内存在,组织学切片显示信号缺失部位与铁颗粒标记细胞相一致。结论纳米级超顺磁性铁氧体颗粒标记的大鼠BMSCs经门静脉移植后可以通过1.5T场强行MRI活体示踪,为临床干细胞移植的应用提供可行的示踪方法。 | 王平 王建华 颜志平 胡美玉 徐鹏举 周梅玲 严福华 FAN Sheung-tat LUK John-m | 2006 | 中华放射学杂志2006，40，2： | 16 |
| 5 | 血液透析病人生存质量质性研究显示文摘[目的]探讨血液透析病人的生存质量及其影响因素。[方法]采用质性研究中现象学研究法,对15例血液透析病人进行半结构式深入访谈,并运用Colaizzi分析法对资料进行分析。[结果]5个层面8个主题被提炼,生理层面:生理不适的困扰;精神、心理层面:焦虑(等待肾源及对未来的不确定感),抑郁、失落、沮丧(各种消极的情绪影响生存质量);经济层面:沉重的经济负担降低了生存质量;社会层面:无法履行社会职能,家庭支持是面对困难的力量;病人需求层面:完善的社会支持系统及医疗保健制度,相关健康教育知识的普及。[结论]开展以病人为中心的护患交流,提供个性化的护理措施,促进病人生理、心理、社会功能方面的适应,提高病人的生存质量。 | 喻惠丹 Weety Suet-Ching Luk 李斯俭 | 2008 | 护理研究(中旬版)2008，22，8： | 14 |
| 6 | Dickkopfs and Wnt/β-catenin signalling in liver cancer显示文摘Liver cancer is the fifth and seventh most common cause of cancer in men and women,respectively.Wnt/β-catenin signalling has emerged as a critical player in both the development of normal liver as well as an oncogenic driver in hepatocellular carcinoma(HCC).Based on the current understanding,this article summarizes the possible mechanisms for the aberrant activation of this pathway with specific focus on HCC.Furthermore,we will discuss the role of dickkopfs(DKKs)in regulating Wnt/β-catenin signalling,which is poorly understood and understudied.DKKs are a family of secreted proteins that comprise at least four members,namely DKK1-DKK4,which act as inhibitors of Wnt/β-catenin signalling.Nevertheless,not all members antagonize Wnt/β-catenin signalling.Their functional significance in hepatocarcinogenesis remains to be further characterized for which these studies should provide new insights into the regulatory role of DKKs in Wnt/β-catenin signalling in hepatic carcinogenesis.Because of the important oncogenic roles,there are an increasing number of therapeutic molecules targetingβ-catenin and the Wnt/β-catenin pathway for potential therapy of HCC. | Sarwat Fatima Nikki P Lee John M Luk | 2011 | World Journal of Clinical Oncology2011，2，8： | 11 |
| 7 | Hazard-evaluation-oriented Moving Horizon Parallel Steering Control for Driver-Automation Collaboration During Automated Driving显示文摘Prompted by emerging developments in connected and automated vehicles, parallel steering control, one aspect of parallel driving, has become highly important for intelligent vehicles for easing the burden and ensuring the safety of human drivers. This paper presents a parallel steering control framework for an intelligent vehicle using moving horizon optimization.The framework considers lateral stability, collision avoidance and actuator saturation and describes them as constraints, which can blend the operation of a human driver and a parallel steering controller effectively. Moreover, the road hazard and the steering operation error are employed to evaluate the operational hazardous of an intelligent vehicle. Under the hazard evaluation,the intelligent vehicle will be mainly operated by the human driver when the vehicle operates in a safe and stable manner.The automated steering driving objective will play an active role and regulate the steering operations of the intelligent vehicle based on the hazard evaluation. To verify the effectiveness of the proposed hazard-evaluation-oriented moving horizon parallel steering control approach, various validations are conducted, and the results are compared with a parallel steering scheme that does not consider automated driving situations. The results illustrate that the proposed parallel steering controller achieves acceptable performance under both conventional conditions and hazardous conditions. | Hongyan Guo Linhuan Song Jun Liu Fei-Yue Wang Dongpu Cao Hong Chen Chen Lv Partick Chi-Kwong Luk | 2018 | IEEE/CAA Journal of Automatica Sinica2018，5，6： | 8 |
| 8 | Classification and management of the tandem ossification of the posterior longitudinal ligament and flaval ligament显示文摘目的将为以后的纵的系带(OPLL ) 和 flaval 系带(OFL ) 的双人脚踏车骨化的处理提供适当指南。数据来源关于 OPLL 出版了文章, OFL 用 Medline 和 Embase 被选择电子数据库。学习选择到 2006 年 12 月的从 1980 年 1 月的英语文学搜索被进行。因为许多报导案例在 OFL 研究被合并,为搜索的关键词是 OFL 或 OFL 和 OPLL。第一步揭示了双人脚踏车 OPLL 和 OFL (双人脚踏车骨化) 的 13 份报告被选择的 93 研究。所有学习的结果是案例系列或案例报告并且倡导为双人脚踏车骨化的主要治疗应该是起作用的。外科的临床的结果在大多数报告被评估,主要使用 JOA 得分。性是有预示的价值的唯一的因素。女人的一个更高的比例在失败组被发现。一二 -- 双人脚踏车骨化的阶段分类被开发联系诊断到结果。有针的系带的怀疑的骨化的所有病人应该经历整个脊骨屏蔽的平淡的 MRI 的结论。有外科的治疗的分类的关联需要进一步的研究验证它的实用性。 | GUO Jiong-jiong YANG Hui-lin Kenneth M.C. Cheung TANG Tian-si Keith D.K. Luk | 2009 | Chinese Medical Journal2009，，2： | 8 |
| 9 | Full-space Cloud of Random Points with a Scrambling Metasurface显示文摘With the rapid progress in computer science,including artificial intelligence,big data and cloud computing,full-space spot generation can be pivotal to many practical applications,such as facial recognition,motion detection,augmented reality,etc.These opportunities may be achieved by using diffractive optical elements(DOEs)or light detection and ranging(LIDAR).However,DOEs suffer from intrinsic limitations,such as demanding depth-controlled fabrication techniques,large thicknesses(more than the wavelength),Lambertian operation only in half space,etc.LIDAR nevertheless relies on complex and bulky scanning systems,which hinders the miniaturization of the spot generator.Here,inspired by a Lambertian scatterer,we report a Hermitian-conjugate metasurface scrambling the incident light to a cloud of random points in full space with compressed information density,functioning in both transmission and reflection spaces.Over 4044 random spots are experimentally observed in the entire space,covering angles at nearly 90°.Our scrambling metasurface is made of amorphous silicon with a uniform subwavelength height,a nearly continuous phase coverage,a lightweight,flexible design,and low-heat dissipation.Thus,it may be mass produced by and integrated into existing semiconductor foundry designs.Our work opens important directions for emerging 3D recognition sensors,such as motion sensing,facial recognition,and other applications. | Zile Li Qi Dai Muhammad Q.Mehmood Guangwei Hu Boris Luk’yanchuk Jin Tao Chenglong Hao Inki Kim Heonyeong Jeong Guoxing Zheng Shaohua Yu Andrea Alù Junsuk Rho Cheng-Wei Qiu | 2018 | Light(Science & Applications)2018，7，1： | 6 |
| 10 | Comparing the removal of polycyclic aromatic hydrocarbons in soil after different bioremediation approaches in relation to the extracellular enzyme activities显示文摘A 120-day experiment was conducted to compare the removal of polycyclic aromatic hydrocarbons(PAHs) from agricultural soil after natural attenuation(NA), phytoremediation(P), mycoremediation(M), and plant-assisted mycoremediation(PAM) approaches in relation to the extracellular enzyme activities in soil. The NA treatment removed the total soil PAH content negligibly. The P treatment using maize(Zea mays) enhanced only the removal of low and medium molecular PAHs. The Pleurotus ostreatus cultivated on 30–50 mm wood chip substrate used in M treatment was the most successful in the removal of majority PAHs. Therefore,significantly(p < 0.05) highest total PAH removal by 541.4 μg/kg dw(dry weight)(36%) from all tested M treatments was observed. When using the same fungal substrate together with maize in PAM treatment, the total PAH removal was not statistically different from the previous M treatment. However, the maize-assisted mycoremediation treatment significantly boosted fungal biomass, microbial and manganese peroxidase activity in soil which strongly correlated with the removal of total PAHs. The higher PAH removal in that PAM treatment could be reflected in the following post-harvest time. Our suggested M and PAM approaches could be promising in situ bioremediation strategies for PAH-contaminated soils. | Zdeněk Ko?ná? Tereza ?ástková Lucie Wiesnerová Luká? Praus Ivan Jablonsky Martin Koudela Pavel Tlusto? | 2019 | Journal of Environmental Sciences2019，31，2： | 6 |
| 11 | Cryopreservation for delayed circulating tumor cell isolation is a valid strategy for prognostic association of circulating tumor cells in gastroesophageal cancer显示文摘AIM To demonstrate the feasibility of cryopreservation of peripheral blood mononuclear cells(PBMCs) for prognostic circulating tumor cell(CTC) detection in gastroesophageal cancer.METHODS Using 7.5 m L blood samples collected in EDTA tubes from patients with gastroesopheagal adenocarcinoma, CTCs were isolated by epithelial cell adhesion molecule based immunomagnetic capture using the Iso Flux platform. Paired specimens taken during the same blood draw(n = 15) were used to compare number of CTCs isolated from fresh and cryopreserved PBMCs. Blood samples were processed within 24 h to recover the PBMC fraction, with PBMCs used for fresh analysis immediately processed for CTC isolation. Cryopreservation of PBMCs lasted from 2 wk to 25.2 mo(median 14.6 mo). CTCs isolated from pre-treatment cryopreserved PBMCs(n = 43) were examined for associations with clinicopathological variables and survival outcomes.RESULTS While there was a significant trend to a decrease in CTC numbers associated with cryopreserved specimens(mean number of CTCs 34.4 vs 51.5, P = 0.04), this was predominately in samples with a total CTC count of > 50, with low CTC count samples less affected(P = 0.06). There was no significant association between the duration of cryopreservation and number of CTCs. In cryopreserved PBMCs from patient samples prior to treatment, a high CTC count(> 17) was associated with poorer overall survival(OS)(n = 43, HR = 4.4, 95%CI: 1.7-11.7, P = 0.0013). In multivariate analysis, after controlling for sex, age, stage, ECOG performance status, and primary tumor location, a high CTC count remained significantly associated with a poorer OS(HR = 3.7, 95%CI: 1.2-12.4, P = 0.03). CONCLUSION PBMC cryopreservation for delayed CTC isolation is a valid strategy to assist with sample collection, transporting and processing. | Daniel Brungs David Lynch Alison WS Luk Elahe Minaei Marie Ranson Morteza Aghmesheh Kara L Vine Martin Carolan Mouhannad Jaber Paul de Souza Therese M Becker | 2018 | World Journal of Gastroenterology2018，24，7： | 5 |
| 12 | Effect of aerobic and anaerobic exercises on glycemic control in type 1 diabetic youths显示文摘AIM:To evaluate the long-term effect of aerobic and/or anaerobic exercise on glycemic control in youths with type 1 diabetes.METHODS:Literature review was performed in spring and summer 2014 using Pub Med/MEDLINE,Google Scholar,Scopus,and Science Direct with the following terms:aerobic,anaerobic,high-intensity,resistance,exercise/training,combined with glycemic/metabolic control,glycated haemoglobin A1c(Hb A1c) and type 1diabetes.Only peer-reviewed articles in English were included published in the last 15 years.It was selected from 1999 to 2014.Glycemic control was measured with Hb A1 c.Studies with an intervention lasting at least 12 wk were included if the Hb A1 c was measured before and after the intervention.RESULTS:A total of nine articles were found,and they were published between the years of 2002-2011.The sample size was 401 diabetic youths(166 males and 235 females) with an age range of 10-19 years except one study,in which the age range was 13-30 years.Study participants were from Australia,Tunisia,Lithuania,Taiwan,Turkey,Brazilia,Belgium,Egypt and France.Four studies were aerobic-based,four were combined aerobic and anaerobic programs,and one compared aerobic exercise to anaerobic one.Available studies had insufficient evidence that any type of exercise or combined training would clearly improve the glycemic control in type 1 diabetic youth.Only three(two aerobic-based and one combined) studies could provide a significant positive change in glycemic control.CONCLUSION:The regular physical exercise has several other valuable physiological and health benefits that justify the inclusion of exercise in pediatric diabetes treatment and care. | Andrea Lukács László Barkai | 2015 | World Journal of Diabetes2015，6，3： | 5 |
| 13 | A meta-analysis of soluble suppression of tumorigenicity 2 (sST2) and clinical outcomes in pulmonary hypertension显示文摘 | King Sum Luk Christina Ip Meng-Qi GONG Sunny Hei WONG William KK Wu Mei DONG Guang-Ping LI Ka Pang Chan Yi-Mei DU Tong LIU Martin CS Wong David Shu Cheong Hui Gary Tse | 2017 | Journal of Geriatric Cardiology2017，14，12： | 5 |
| 14 | Progression from impaired fasting glucose to type 2 diabetes mellitus among C hinese subjects with and without hypertension in a primary care setting 在中国初级保健机构中合并以及不合并高血压的受试者从空腹血糖受损进展到2型糖尿病的调查显示文摘 | Sau Nga Fu Wan Luk Carlos King Ho Wong Kwok Leung Cheung | 2014 | Journal of Diabetes2014，，5： | 5 |
| 15 | Hepatic tight junctions:From viral entry to cancer metastasis显示文摘The tight junction (TJ) is a critical cellular component for maintenance of tissue integrity, cellular interactions and cell-cell communications, and physiologically functions as the 'great wall' against external agents and the surrounding hostile environment. During the host-pathogen evolution, viruses somehow found the key to unlock the gate for their entry into cells and to exploit and exhaust the host cells. In the liver, an array of TJ molecules is localized along the bile canaliculi forming the blood-biliary barrier, where they play pivotal roles in paracellular permeability, bile secretion, and cell polarity. In pathology, certain hepatic TJ molecules mediate virus entry causing hepatitis infection; deregulation and functional abnormality of the TJ have also been implicated in triggering liver cancer development and metastasis. All these findings shed new insights on the understanding of hepatic TJs in the development of liver disease and provide new clues for potential intervention. | Nikki P Lee John M Luk | 2010 | World Journal of Gastroenterology2010，16，3： | 4 |
| 16 | 黄土丘陵区洞穴侵蚀产流产沙规律初步研究显示文摘通过对黄土丘陵沟壑区羊道沟试验区 6个洞穴系统连续两年共11场暴雨产流产沙资料的分析,认为黄土丘陵沟壑区洞穴侵蚀的重点是梯田、缓坡地和植被覆盖较好的地方。同时初步揭示了该区洞穴侵蚀的产流产沙规律。 | 朱同新 蔡强国 高平 魏中平 Luk S H Tayor Helen | 1992 | 水土保持学报1992，6，1： | 4 |
| 17 | 基于混合式两阶段的动态部分重构FPGA软硬件划分算法显示文摘动态部分重构的特性大大提高了硬件设计的灵活性,但传统的软硬件划分算法不再适用于针对这类硬件的系统设计。部分研究考虑了动态部分重构的特性,并建立了混合整数线性规划(MILP)模型进行求解。但是由于MILP自身的限制,求解时间特别长,只能处理规模较小的问题。为了能够处理规模较大的问题,并且缩短求解时间,该文对MILP方法进行了详细的分析,并且通过启发式算法确定部分关键任务的状态,从而减小MILP的规模,加快求解速度。实验结果表明:与传统的数学规划方法相比,在求解质量不变的情况下,该算法可以得到最高约200倍的速度提升。 | 马昱春 张超 Luk Wayne | 2016 | 清华大学学报(自然科学版)2016，56，3： | 4 |
| 18 | Effects of Organic Matter-Rich Amendments on Selenium Mobility in Soils显示文摘Soil organic matter (SOM) plays an important role in the Se dynamics in soil. The potential effects of vermicompost and digestate as important sources of SOM on selenium (Se) mobility were assessed in this study. Three soils differing in their physicochemical parameters, fluvisol, chernozem, and luvisol, were chosen, and three types of vermicomposts based on various bio-waste materials as digestate (vermicompost 1), kitchen waste with woodchips (vermicompost 2), and garden bio-waste (vermicompost 3) were used due to their high organic matter content. Additionally, digestate samples alone were applied. To evaluate the potential effect of vermicompost application on sorption characteristics of soils, batch sorption experiments were performed. The results showed a predominant effect on Se species in the soils, where selenite sorbed more intensively compared to selenate, regardless of the soil and ameliorative material applied. In the control, the soil sorption ability of selenite tended to decrease in the order: fluvisol > luvisol > chernozem. However, these differences were not significant. Moreover, the effects of the ameliorative materials depended on both soil and amendment used. In fluvisol, all the amendment applications resulted in a decrease in distribution coefficient ( K d values) of Se, whereas in chernozem, this effect was observed only for the digestate-based vermicompost 1. Increasing K d levels were reported in luvisol treated with digestate;the application of garden bio-waste-based vermicompost 3 tended to decrease the K d values. Further studies are required on long-term effects of these amendments on Se mobility in soils and the role of individual organic matter fractions in this context. | Petra SMAZíKOVá Luká? PRAUS Jirina SZáKOVá Jana TREMLOVá Ale? HANC Pavel TLUSTOS | 2019 | Pedosphere2019，29，6： | 3 |
| 19 | 血浆蛋白质组模式预测鼠不同时期肝纤维化显示文摘蛋白质组模式在肿瘤性疾病的诊断方面应用已经较多,显示了良好的应用前景,但关于蛋白质组模式在肝纤维化时的改变较少有文献报道。为寻找一种新的、理想的诊断肝纤维化的方法,我们制备了不同时期肝纤维化鼠模型,用蛋白芯片技术检测鼠血浆标本,根据血浆蛋白模式建立不同时期肝纤维化判别函数,并用鼠肝纤维化模型验证该判别函数的准确性。 | 张其胜 John M Luk | 2006 | 中华肝脏病杂志2006，14，9： | 3 |
| 20 | Effect of Osmotic Stress in Early Stages of Ontogenesis on Root Respiration, Growth, Sugar Content,and Cell Injury in Maize Seedlings Differing in Drought Sensitivity显示文摘有到干旱的不同敏感的玉米(Zea mays L.) 的栽培变种为 24 h 暴露于 0.3 mol/L 山梨糖醇(-1.4 MPa 水潜力) 。显著地浇缺乏的暴露减少了射击(coleoptile 和胚轴) 和根的生长。射击生长多于根的生长被禁止。渗透的应力提高了可溶的糖的累积。电解质漏,一个房间损害索引,稍微在 0.3 mol/L 山梨糖醇以后被增加。呼吸当面被测量并且 2,6-dichlorophenol indophenol 的缺席。2, 6-Dichlorophenol indophenol 没影响呼吸率,因为统计上相等的结果在两个条件下面被观察。全部的呼吸(vt ) 在 osmoticum 处理以后减少了。在在分析的栽培变种之中的 vt 没有重要差别。在 vt 的减少被衰落在细胞色素的活动和能力引起(vcyt, Vcyt ) 并且其他的小径(valt, Valt ) 呼吸。高剩余呼吸(vres ) 被观察,直到 27% 全部的不受禁令约束的呼吸。使用清楚地显示了那联合的 uncoupler 的结果在渗透的应力的 24 h 以后被维持。呼吸率的恢复与非强调的控制率的是可比较的。根据这些观察,没有可能的 mitochondrial 损坏被期望。水缺乏没导致其他的 oxidase 的刺激,因此我们假设其他的小径的刺激不与干旱压力抵抗有关;更确切地说,其他的小径的功能是在对变化环境的回答平衡碳新陈代谢和电子运输。 | Lukás, Kolarovic Miroslava Luxová Peter Valentovic | 2006 | Journal of Integrative Plant Biology2006，48，7： | 3 |
您所在的机构暂未开通此部分的功能，请联系管理员