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| 1 | Risk factors of intrahepatic cholangiocarcinoma in patients with hepatolithiasis:a case-control study显示文摘BACKGROUND:Why 3.3% to 10% of all patients with hepatolithiasis develop intrahepatic cholangiocarcinoma (ICC) remains unknown.We carried out a hospital-based case-control study to identify risk factors for the development of ICC in patients with hepatolithiasis in China.METHODS:Eighty-seven patients with pathologically diagnosed hepatolithiasis associated with ICC and 228 with hepatolithiasis alone matched by sex,age (±2 years),hospital admittance and place of residence were interviewed during the period of 2000-2008.Odds ratios (OR) and 95% confidence intervals (CI) were calculated for each risk factor.RESULTS:Among the patients with hepatolithiasis associated with ICC,the mean age was 57.7 years and 61.0% were female Univariate analysis showed that the significant risk factors for ICC development in hepatolithiasis were smoking,family history of cancer,appendectomy during childhood (under age 20),and duration of symptoms >10 years.In multivariate stepwise logistic regression analysis,smoking (OR=1.931,95% CI:1.000-3.731),family history of cancer (OR=5.175,95% CI:1.216-22.022),and duration of symptoms >10 years (OR=2.348 95% CI:1.394-3.952) were independent factors.CONCLUSION:Smoking,family history of cancer and duration of symptoms >10 years may be risk factors for ICC in patients with hepatolithiasis. | Zhen-Yu Liu,Yan-Ming Zhou,Le-Hua Shi and Zheng-Feng YinAuthor Affiliations:Molecular Oncology Laboratory and Department of Comprehensive Treatment I,Eastern Hepatobiliary Surgery Hospital,Second Military Medical University,Shanghai 200438,China Department of Hepato-Biliary-Pancreato-Vascular Surgery,First Affiliated Hospital,Xiamen University,Xiamen 361003,China | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，6： | 21 |
| 2 | Metal-organic framework-derived porous shuttle-like vanadium oxides for sodium-ion battery application显示文摘有分层的结构的钒氧化物为锂离子电池和钠离子电池(亲族) 正在答应候选人。自我模板途径,从金属器官的框架(MOF ) 包含转变进多孔的金属氧化物,是完成理想的电气化学的性能的一个新奇、有效的方法。在这研究,多孔的像梭的钒氧化物(即, V 2 O 5, V 2 O 3/C) 被与一个特定的锻烧过程把 MIL-88B (V) 用作先锋成功地准备。作为 proof-of-concept 应用, asprepared 多孔的像梭的 V 2 O 3/C 为亲族被用作阳极材料。多孔的像梭的 V 2 与金属性的行为有固有的分层的结构的 O 3/C, ,展出优秀电气化学的性质。417, 247, 202, 176, 164,和 149 mAhants 的显著的率能力,仅仅 CC 一?? | Yangsheng Cai Guozhao Fang Jiang Zhou Sainan Liu Zhigao Luo Anqiang Pan Guozhong Cao I Shuquan Liang | 2018 | Nano Research2018，11，1： | 12 |
| 3 | Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction显示文摘 | Xiao-E Jia Ke Ma Tao Xu Lei Gao Shuang Wu Cong Fu Wenjuan Zhang Zhizhang Wang Kaiyu Liu Mei Dong Changbin Jing Chunguang Ren Zhiwei Dong Yi Chen Yi Jin Qiuhua Huang Xing Chang Min Deng Li Li Lingfei Luo Jun Zhu Yongjun Dang Hung-Chun Chang Leonard I Zon Yi Zhou Saijuan Chen Weijun Pan | 2015 | Cell Research2015，25，8： | 8 |
| 4 | Organic carbon isotope and molecular fossil records of vegetation evolution in central Loess Plateau since 450 kyr显示文摘Significant uncertainties remain regarding the temporal evolution of natural vegetation during the Quaternary, and drivers of past vegetation change, on the Chinese Loess Plateau(CLP). This study presents analyses of total organic carbon isotopic composition(TOC) and n-alkane ratios(C31/C27) from the Lingtai loess-palaeosol sequence on the central CLP over the last 450 kyr. The results demonstrate that the vegetation in this region comprised a mix of C_3 and C_4 plants of herb and woody growth-form. C_3 plants dominated for most of the last 450 kyr, but this did not lead to extensive forest. C_3 woody plants were more abundant in MIS9(S3 period) and MIS5(S1 period) during warm and humid climate conditions. Herbs increased in the region since 130 kyr, possibly as a result of increased aridity. On the orbital timescales, there was a reduction of C_3 herbal plants in MIS11(S4) than in MIS12(L5), and in Holocene than in the last glacial period. Our isotope and n-alkane proxy records are in agreement with Artemisia pollen changes in the region, which is/was the dominant species in this area and varying due to different heat and water conditions between glacial and interglacial periods. Though the climate in MIS1(S0) was similar to that in MIS11(S4), a significant increase in woody plants during the Holocene suggests the impact of human activities and ecological effects of changes in fire activity. | ZHOU Bin WALI Guzalnur Francien PETERSE Michael I BIRD | 2016 | Science China Earth Sciences2016，59，6： | 7 |
| 5 | STELLADELIN D,A NEW CYCLIC UNDECAPEPTIDE FROM STELLARIA DELAVAYI显示文摘STELLADELIND,ANEWCYCLICUNDECAPEPTIDEFROMSTELLARIADELAVAYI￥YuRuiZHAO;JunZHOU;XianKaiWANG;XiaoLinHUANG;HouMingWU;ChangXiangCHEN... | Yu Rui ZHAO Jun ZHOU Xian Kai WANG Xiao Lin HUANG Hou Ming WU Chang Xiang CHENG (Depepartment of Medicinal Chemistry of Natural Products,School ofPharmacy, West China University of Medical Sciences,Chengdu, 610041)(Laboratory of Phytochemistry,Kunming I | 1996 | Chinese Chemical Letters1996，7，3： | 4 |
| 6 | Structural insights into SUN-KASH complexes across the nuclear envelope显示文摘nucleoskeleton 和细胞骨架(LINC ) 的连接器建筑群由阳光和 KASH 包含域的蛋白质组成并且衔接原子信封的内部、外部的膜。LINC 建筑群在原子放,房间极化和细胞的僵硬起关键作用。以前,我们报导了人的 SUN2 的 homotrimeric 结构。我们现在决定了人的 SUN2-KASH 建筑群的水晶结构。在复杂结构, SUN 领域 homotrimer 绑在三独立 “ hook”相似 KASH 肽。在建筑群的 SUN 领域的全面符合构造非常处于它的 apo 状态类似于 SUN 领域。一个主要 conformational 变化包含 KASH 固定的阳光领域的 AA'-loop,它重排形成微型 β与 KASH 肽交往的表。KASH 领域的磅主题在 SUN 领域的 homotrimeric 接口上紧适合进一个恐水病的衣袋,我们它称为双性人衣袋。而且, SUN 领域 homotrimer 三明治的二邻近的 protomers 由结合的恐水病的相互作用和氢的 KASH 领域。这些有约束力的地点的变化在 vitro 破坏或减少在 SUN 和 KASH 域之间的协会。另外, transfection 野类型,然而并非变异, SUN2 在 Ovcar-3 房间支持房间移植。这些结果提供 LINC 建筑群的一个结构的模型,它为另外的学习是必要的物理、功能在细胞质和核质之间联合。 | Wenjia Wang Zhubing Shi Shi Jiao Cuicui Chen Huizhen Wang Guoguang Liu Qiang Wang Yun Zhao Mark I Greene Zhaocai Zhou | 2012 | Cell Research2012，22，10： | 3 |
| 7 | Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors显示文摘 | Li M Lee KF Lu Y Clarke I Shih D Eberhart C Collins VP Van Meter T Picard D Zhou L Boutros PC Modena P Liang ML Scherer SW Bouffet E Rutka JT Pomeroy SL Lau CC Taylor MD Gajjar A Dirks PB Hawkins CE Huang A. | 2009 | 中国神经肿瘤杂志2009，7，4： | 3 |
| 8 | A NEW CYCLOPEPTIDE FROM ARENARIA JUNCEA显示文摘A NEW CYCLOPEPTIDE FROM ARENARIA JUNCEAANEWCYCLOPEPTIDEFROMARENARIAJUNCEAYuRuiZHAO;JunZHOU;XianKaiWANG;XiaoLinHUANG;HouMingWU... | Yu Rui ZHAO Jun ZHOU Xian Kai WANG Xiao Lin HUANG Hou Ming WU Tong Fang ZHAO(Department of Medicinal Chemistry of Natural Products, School of Pharmacy, West China University of Medical Sciences. Chengdu, 610041)(Laboratory of Phytochemistry, Kunming I | 1994 | Chinese Chemical Letters1994，5，9： | 2 |
| 9 | TWO NEW OLEANOLIC ACID SAPONINS FROM ASTER YUNNANENSIS显示文摘TWONEWOLEANOLICACIDSAPONINSFROMASTERYUNNANENSIS￥YuSHAO;BingNanZHOU;LongZeLINandGeoffreyA.Cofdell(ShanghaiinstituteofMatstheMe... | Yu SHAO Bing Nan ZHOU Long Ze LIN and Geoffrey A. Cofdell (Shanghai institute of Matsthe Medica, Academic Sinica, Shanghai 2O0031 Program for Collaborative research in the Pharmaceutical Sciences, Coilege of pharmacy,Unlversity of lllinois at Chicago, I | 1994 | Chinese Chemical Letters1994，5，10： | 2 |
| 10 | On the validity of ESO type methods in topology optimization显示文摘 | Zhou M Rozvany G I N | 2001 | Structural and Multidisciplinary Optimization2001，21，： | 1 |
| 11 | Evaluation of induction of CYP3A mRNA using the HepG2 cell line and reverse transcription-PCR显示文摘 | Sumida A Yamamoto I Zhou Q | 1999 | Biol Pharm Bull1999，22，1： | 1 |
| 12 | Role of AT1 receptors and NAD(P)H oxidase in diabetes-aggravated ischemic brain injury显示文摘 | Kusaka I Kusaka G Zhou C | 2004 | Physiol Heart Circ Physiol2004，286，6： | 1 |
| 13 | Cryoanalgesia Electrophysiology at different temperatures显示文摘 | Zhou I Shao Z Ou S | 2003 | Cryobiology2003，46，1： | 1 |
| 14 | 查看详情显示文摘 | Wang D. P Belharouak I Zhou G. W Amine K | | 0，，08： | 1 |
| 15 | The COC Algorithm,part I:Cross-section Optimization Sizing显示文摘 | Rozvany G I N Zhou M | 1991 | Computer Methods in Applied Mechanics and Engineering1991，89，： | 1 |
| 16 | The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL- 17^+ T helper cells 显示文摘 | Ivanov I I McKenzie B S Zhou L | 2006 | Cell2006，126，： | 1 |
| 17 | Preparation and rate capability of Li4Ti5O12 hollow - sphere anode material 显示文摘 | Jiang C H Zhou Y Honma I | 2007 | Journal of Power Sources2007，166，2： | 1 |
| 18 | Non-linear, non- invasive method for seizure anticipation in focal epilepsy 显示文摘 | Li Dingzhou Zhou Weiping Drury I | 2003 | Mathematical Biosciences2003，186，1： | 1 |
| 19 | The COC algorithm,part2:topological,geometrical & generalized shape optimization显示文摘 | ZHOU M ROZVANG G I N | 1991 | Comp Mech Appl Eng1991，89，： | 1 |
| 20 | The COC algorithm, part II: topological, geometry and generalized shape optimization 显示文摘 | ZHOU M ROZVANY G I N | 1991 | Computer Methods in Applied Meehanies and Engineering1991，89，13： | 1 |
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