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1ACCF/SCAI/SVMB/SIR/ASITN 2007年颈动脉支架置入术临床专家共识文件——美国心脏病学会基金会特别工作组关于临床专家共识文件的报告(ACCF/SCAI/SVMB/SIR/ASITN颈动脉支架置入术临床专家共识文件委员会):与美国介入与治疗神经放射学学会、心血管造影和介入治疗学会、血管医学和生物学学会、介入放射学学会联合发布显示文摘序言 本文件在美国心血管造影和介入治疗学会(Society for Cardiovascular Angiography and Interventions,SCAI)、血管医学和生物学学会(Society for Vascular Medicine and Biology,SVMB)、介入放射学学会(Society of Interventional Radiology,SIR)、美国介入与治疗神经放射学学会(American Society of Interventional & Therapeutic Neuroradiology,ASITN)共同倡导下,Bates ER Babb JD Casey DE Jr Cates CU Duckwiler GR Feldman TE Gray WA Ouriel K Peterson ED Rosenfield K Rundback JH Safian RD Sloan MA White CJ 刘慧慧(译) 吴延华(译) 靳勇(译) 曹勇军(译) 刘春风(译) 2007国际脑血管病杂志2007,15,5:52
2患者肠道微生物群失调与肠上皮屏障功能障碍显示文摘最近的证据表明,在动物模型中,肠道病理学和微生物组与高血压之间存在联系。然而,这种关联在人类中是否存在尚不清楚。因此,该研究的目的是检验高血压患者具有明显特异的肠道微生物组以及肠上皮屏障功能标记物和微生物组组成可以预测收缩压变化的假设。研究者通过鸟枪法宏基因组学分析粪便样本显示微生物分类和功能变化,结果显示高血压患者和对照受试者之间丁酸盐产生存在差异。Kim S Goel R Kumar A Qi Y Lobaton G Hosaka K Mohammed M Handberg EM Richards EM Pepine CJ Raizada MK 刘青 叶鹏 2018中华高血压杂志2018,26,9:45
3GA_3、2,4-D、B和蔗糖对梨花粉生活力及花粉生长速度的影响(英文)显示文摘以5个亚洲梨品种为试材,通过离体培养研究了花穗中花的着生部位,不同浓度的GA3、2,4-D和蔗糖对花粉生活力、花粉管生长速度的影响。结果表明,不同品种的花粉生活力差异明显,黄花花粉萌发快;新世纪花粉生活力强,花粉管生长迅速。花的着生位置及花器官的发育程度对花粉生活力有明显影响,边花的生活力比中心花强。不同浓度的B、2,4-D、GA3对花粉萌发及花粉管生长均有不同程度的影响,高浓度的GA3、2,4-D抑制花粉管的生长,但浓度较高的蔗糖能促进花粉粒的萌发和生长,且两者呈正相关(R2=0.983)。谢深喜 罗先实 吴月嫦 Lovatt CJ 2004果树学报2004,21,4:23
4Current status of laparoscopic and robotic ventral mesh rectopexy for external and internal rectal prolapse显示文摘External and internal rectal prolapse with their affiliated rectocele and enterocele, are associated with debilitating symptoms such as obstructed defecation, pelvic pain and faecal incontinence. Since perineal procedures are associated with a higher recurrence rate, an abdominal approach is commonly preferred. Despite the description of greater than three hundred different procedures, thus far no clear superiority of one surgical technique has been demonstrated. Ventral mesh rectopexy(VMR) is a relatively new and promising technique to correct rectal prolapse. In contrast to the abdominal procedures of past decades, VMR avoids posterolateral rectal mobilisation and thereby minimizes the risk of postoperative constipation. Because of a perceived acceptable recurrence rate, good functional results and low mesh-related morbidity in the short to medium term, VMR has been popularized in the past decade. Laparoscopic or robotic-assisted VMR is now being progressively performed internationally and several articles and guidelines propose the procedure as the treatment of choice for rectal prolapse. In this article, an outline of the current status of laparoscopic and robotic ventral mesh rectopexy for the treatment of internal and external rectal prolapse is presented.Jan J van Iersel Tim JC Paulides Paul M Verheijen John W Lumley Ivo AMJ Broeders Esther CJ Consten 2016World Journal of Gastroenterology2016,22,21:20
5Leber's hereditary optic neuropathy is associated with the mitochondrial ND4 G11696A mutation in five Chinese families显示文摘Zhou XT Wei QP Yang L Tong Y Zhao FX Lu CJ Qian YP Sun YH Lu F Qu J Guan MX 2006中国生物学文摘2006,20,4:18
6Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial显示文摘Martijn HGM van der Pas Eva Haglind Miguel A Cuesta Alois Fürst Antonio M Lacy Wim CJ Hop Hendrik Jaap Bonjer 2013Lancet Oncology2013,,:17
72型糖尿病患者个体化血糖控制目标和药物治疗显示文摘'有效管理糖尿病全球合作组织'(下称'糖尿病全球合作组织')成立的宗旨是为临床提供实用指南以改善糖尿病患者的预后,制定并修改相关策略以改善T2DM患者血糖控制情况。糖尿病全球合作组织提倡对糖尿病患者实行个体化治疗方案,明确需要特殊考虑T2DM患者亚组人群。这篇文章基于此前发表的文献,扩大了实用指南的范围,包括有并发症的新诊断T2DM患者和妊娠期糖尿病(GDM)患者。良好血糖控制是T2DM管理的基石,在预防或延缓糖尿病并发症的发生、发展过程中发挥重要作用。个体化治疗目标和安全及时的血糖达标治疗方案至关重要。另外,还需制定更全面的护理计划以降低心血管风险和改善患者预后。张晓梅 纪立农 Bailey CJ Aschner P Stefano Del Prato LaSalle J JI Li-nong Matthaei S 2014中国糖尿病杂志2014,22,10:16
8Effects of Ginkgo biloba extract on cell proliferation and cytotoxicity in human hepatocellular carcinoma cells显示文摘AIM: To study the effect of Ginkgo biloba extract (EGb 761)containing 22-27% flavonoids (ginkgo-flavone glycosides) and 5-7% terpenoids (ginkgolides and bilobalides) on cell proliferation and cytotoxicity in human hepatocellular carcinoma (HCC) cells. METHODS: Human HCC cell lines (HepG2 and Hep3B) were incubated with various concentrations (0-1 000 mg/L) of EGb 761 solution. After 24 h incubation, cell proliferation andcytotoxicity were determined by 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) assay and lactate dehydrogenase (LDH) release, respectively. After 48 h incubation, the expression of proliferating cell nuclear antigen (PCNA) and p53 protein was measured by Western blotting. RESULTS: The results showed that EGb 761 (50-1 000 mg/L)significantly suppressed cell proliferation and increased LDH release (P<0.05) in HepG2 and Hep3B cells compared with the control group. The cell proliferation of HepG2 and Hep3B cells treated with EGb 761 (1 000 mg/L) was 45% and 39% of the control group (P<0.05), respectively. LDH release of HepG2 cells without and with EGb 761 (1 000 mg/L) treatment was 6.7% and 37.7%, respectively, and that of Hep3B cells without and with EGb 761 (1 000 rag/L) treatment was 7.2% and 40.3%, respectively. The expression of PCNA and p53 protein in HepG2 cells treated with EGb 761 (1 000 mg/L) was 85% and 174% of the control group, respectively. CONCLUSION: Ginkgo bilobaextract significantly can suppress proliferation and increase cytotoxicity in HepG2 and Hep3B cells. Additionally, Ginkgo biloba extract can decrease PCNA and increase p53 expression in HepG2 cells.Jane CJ Chao 2004World Journal of Gastroenterology2004,10,1:16
9最经济的灌水法──地下滴灌显示文摘最经济的灌水法──地下滴灌C.J.Phene(MaximizingWater—UseEfficiencywithSubsurfaceDripIrrigation《IrrigationJournal》NO.3,1993【英】)美国西部地区70年代遭受能...Phene,CJ 张爱莉 1995灌溉排水1995,14,1:13
10孕前血压及其到妊娠早期的变化:先兆子痫和妊娠期高血压的早期危险因素显示文摘先兆子痫和妊娠期高血压是常见的妊娠并发症,与母婴发病率显著相关。尽管对怀孕期间的危险因素进行了广泛的研究,但大多数患妊娠期高血压疾病的妇女并不被认为是高风险的,预防措施仍不清楚。研究者评估了妊娠前的血压及其到妊娠早期的变化,将其作为妊娠高血压疾病发展新的危险标志。刘青(译) 刘莉(摘/审校) Nobles CJ Mendola P Mumford SL Silver RM Kim K Andriessen VC Connell M Sjaarda L Perkins NJ Schisterman EF 2020中华高血压杂志2020,28,12:12
11Effect of oral epidermal growth factor on mucosal healing in rats with duodenal ulcer显示文摘AIM: To investigate the effect of epidermal growth factor (EGF) on mucosal healing in rats with duodenal ulcer.METHODS: Male Sprague-Dawley rats were randomly divided into sham operation without EGF, sham operation with EGF, duodenal ulcer without EGF, or duodenal ulcer with EGF groups. Additionally, normal rats without operation served as the control group. Duodenal ulcer was induced in rats by 300 mL/L acetic acid. Rats with EGF were orally administered at a dose of 60 μg/kg/day in drinking water on the next day of operation (day 1). Healing of duodenal ulcer was detected by haematoxylin and eosin staining. Cell growth of damaged mucosa was determined by the contents of nucleic acids and proteins. The level of EGF in duodenal mucosa was measured by ELISA.RESULTS: The pathological results showed that duodenal ulcer rats with EGF improved mucosal healing compared with those without EGF after day 5. Duodenal ulcer rats with EGF significantly increased duodenal DNA content compared with those without EGF on day 15 (6.44±0.54mg/g VS 1.45±0.52 mg/g mucosa, P<0.05). Duodenal RNA and protein contents did not differ between duodenal ulcer rats with and without EGF during the experimental period.Sham operation and duodenal ulcer rats with EGF significantly increased duodenal mucosal EGF content compared with those without EGF on day 5 (76.0±13.7 ng/g VS 35.7±12.9ng/g mucosa in sham operation rats, and 68.3±10.9 ng/gVS 28.3±9.2 ng/g mucosa in duodenal ulcer rats, P<0.05).CONCLUSION: Oral EGF can promote mucosal healing of the rats with duodenal ulcer by stimulating mucosal proliferation accompanied by an increase in mucosal EGF content.Jane CJ Chao Kuo-Yu Liu Sheng-Hsuan Chen Chia-Lang Fang Chih-Wei Tsan 2003World Journal of Gastroenterology2003,9,10:9
12RTOG 0211:a phase 1/2 study of radiation therapy with concurrent gefitinib for newly diagnosed glioblastoma patients显示文摘PURPOSE: To determine the safety and efficacy of gefitinib,an epidermal growth factor receptor(EGFR) tyrosine kinase inhibitor,in combination with radiation for newly diagnosed glioblastoma(GBM) patients.METHODS AND MATERIALS: Between March 21,2002,and May 3,2004,Radiation Therapy Oncology Group(RTOG) 0211 enrolled 31 and 147GBM patients in the phase 1 and 2 arms,respectively.Treatment consisted of daily oral gefinitnib started at the time of conventional cranial radiation therapy(RT) and continued post RT for 18 months or until progression.Tissue microarrays from 68 cases were analyzed for EGFR expression.RESULTS: The maximum tolerated dose(MTD) of gefitinib was determined to be 500 mg in patients on non-enzyme-inducing anticonvulsant drugs(non-EIAEDs).All patients in the phase 2 component were treated at a gefitinib dose of 500 mg;patients receiving EIADSs could be escalated to 750 mg.The most common side effects of gefitinib in combination with radiation were dermatologic and gastrointestinal.Median survival was 11.5 months for patients treated per protocol.There was no overall survival benefit for patients treated with gefitinib + RT when compared with a historical cohort of patients treated with RT alone,matched by RTOG recursive partitioning analysis(RPA) class distribution.Younger age was significantly associated with better outcome.Per protocol stratification,EGFR expression was not found to be of prognostic value for gefitinib + RT-treated patients.CONCLUSIONS: The addition of gefitinib to RT is well tolerated.Median survival of RTOG 0211 patients treated with RT with concurrent and adjuvant gefitinib was similar to that in a historical control cohort treated with radiation alone.Chakravarti A Wang M Robins HI Lautenschlaeger T Curran WJ Brachman DG Schultz CJ Choucair A Dolled-Filhart M Christiansen J Gustavson M Molinaro A Mischel P Dicker AP Bredel M Mehta M 2013中国神经肿瘤杂志2013,11,1:8
13Fructus Broussonetae extract improves cognitive function and endoplasmic reticulum stress in Alzheimer's disease models显示文摘This study investigated the effects and possible targets of Fructus Broussonetiae extract,a traditional Chinese medicinal herb,on a model of Alzheimer's disease induced by beta-amyloid peptide 25-35 and D-galactose.The results revealed that intragastric administration of Fructus Broussonetiae significantly increased the expression of immunoglobulin-binding protein,a key factor in the endoplasmic reticulum stress-signaling pathway in rat hippocampus.In contrast,the treatment significantly decreased expression levels of PKR-like endoplasmic reticulum kinase and C/EBP homologous protein,and substantially improved learning,memory and spatial recognition dysfunction in rats.This evidence indicates that Fructus Broussonetiae extract improves spatial learning and memory abilities in rats by affecting the regulation of hippocampal endoplasmic reticulum stress and activation of the apoptosis pathway.Yinghong Li Li Hu Zhengzhi Wu Zhiling Yu Meiqun Cao Kehuan Sun Yu Jin Anmin Wu Andrew CJ Huang 2011Neural Regeneration Research2011,6,30:7
14罹患高血压的非洲裔美国人和美国白人的肠道微生物群及血清代谢物差异显示文摘非洲裔美国人高血压患病率、严重程度和高血压治疗抵抗均高于美国白人。肠道微生物菌群及其代谢产物的不同可能是造成这种现象的原因。为此,Walejko等收集研究人群的粪便和血液样本分别用于肠道微生物群的全基因组测序(whole genome sequencing,WGS)和血清整体非靶向代谢组学研究,对上述假设进行了验证。Walejko JM Kim S Goel R Handberg EM Richards EM Pepine CJ Raizada MK 刘青 叶鹏 2018中华高血压杂志2018,26,9:7
15脉冲染料激光联合外用咪喹莫特与单纯激光治疗鲜红斑痣的初步对比研究显示文摘研究目的评估脉冲染料激光(pulsed dye laser PDL)联合外用咪喹莫特治疗与单纯激光治疗鲜红斑痣的疗效。研究设计对20名亚裔鲜红斑痣受试者的结果进行评估。鲜红斑痣皮损内设置三个治疗测试区:A区用PDL+外用咪喹莫特治疗;B区单纯PDL治疗;C区单纯外用咪喹莫特软膏治疗。治疗后1、3、6和12个月进行随访,利用皮肤光谱检测仪测量血红蛋白指数。苑凯华 Chang CJ Hsiao YC Mihm MC 2011中国激光医学杂志2011,20,1:6
161980—1997年撒哈拉沙漠的面积变化显示文摘我们应用卫星数据和地面降雨测量资料研究了1980-1997年撒哈拉沙漠面积的变化。结合卫星和地面数据,绘制出了撒哈拉-萨赫勒地区每年的200mm年降雨量界线图。尽管撒哈拉沙漠面积发生了非常大的年际变化,但是1980-1997年没有明显的系统性面积增加或减少趋势。撒哈拉沙漠面积从1984年的998000km^2变化为1994年的8600000km^2,1980-1997年间的平均面积是9150000km^2。Tuck.,CJ 李香莲 1999AMBIO-人类环境杂志1999,28,7:6
17Protective effects of Ginkgo biloba extract on the ethanol-induced gastric ulcer in rats显示文摘AIM: To evaluate the preventive effect of Ginkgo bilobaextract (GbE) on ethanol-induced gastric mucosal injuries in rats.METHODS: Female Wistar albino rats were used for the studies. We randomly divided the rats for each study into five subgroups: normal control, experimental control, and three experimental groups. The gastric ulcers were induced by instilling 1 mL 50% ethanol into the stomach. We gaveGbE 8.75, 17.5, 26.25 mg/kg intravenously to the experimental groups respectively 30 min prior to the ulcerative challenge. We removed the stomachs 45 min later. The gastric ulcers,gastric mucus and the content of non-protein sulfhydryl groups (NP-SH), malondialdehyde (MDA), c-Jun kinase (JNK) activity in gastric mucosa were evaluated. The amount of gastric juice and its acidity were also measured. RESULTS: The findings of our study are as follows: (1)GbE pretreatment was found to provide a dose-dependent protection against the ethanol-induced gastric ulcers in rats; (2) the GbE pretreatment afforded a dose-dependent inhibition of ethanol-induced depletion of stomach wall mucus, NP-SH oontents and increase in the lipid peroxidation (increase MDA) in gastric tissue; (3) gastric ulcer induced by ethanolproduced an increase in JNK activity in gastric mucosawhich also significantly inhibited by pretreatment with GbE;and (4) GbE alone had no inhibitory effect on gastric secretionin pylorus-ligated rats.CONCLUSION: The finding of this study showed that GbE significantly inhibited the ethanol-induced gastric lesions in rats. We suggest that the preventive effect of GbE may be mediated through: (1) inhibition of lipid peroxidation;(2) preservation of gastric mucus and NP-SH; and (3)blockade of cell apoptosis.Sheng-Hsuan Chen Yu-Chih Liang Jane CJ Chao Li-Hsueh Tsai Chun-Chao Chang Chia-Chi Wang Shiann Pan 2005World Journal of Gastroenterology2005,11,24:6
182005—2007年儿科分离的流感嗜血杆菌、肺炎链球菌(包括血清型19A)和卡他莫拉菌对常用抗菌药物的敏感性显示文摘Harrison CJ Woods C Stout G 周颖杰 王明贵 2010中国感染与化疗杂志2010,10,1:5
19中国咖啡锈菌(Hemileia vastatrix)生理小种研究显示文摘对我国云南、海南和广东咖啡植区收集到的58个咖啡锈菌菌株标本进行生理小种鉴定,鉴定出小种有7个。各咖啡植区除共同出现Ⅱ号生理小种外,云南咖啡植区还出现Ⅰ,XV,XXIII和XXIV号生理小种;海南则出现VI和XXII号小种;广东咖啡栽培地区未发现有新的生理小种。各咖啡植区新生成的生理小种种类有明显不同。陈振佳 Rodr.,CJ 1998菌物系统1998,17,1:5
20早发性先兆子痫,迟发性先兆子痫和妊娠高血压后的心血管疾病危险因素显示文摘研究表明,有妊娠高血压病史的妇女心血管疾病(cardiovasculardisease,CVD)终生风险增加。这种风险与妊娠相关高血压疾病的严重程度及发病孕周有关。然而,cVD危险因素的差异是否在产后心血管筛查时就已经存在尚不清楚。研究人员将妊娠期高血压疾病患者分为3个亚组,分析CVD危险因素的产后差异。刘莉 叶鹏 Veerbeek JH Hermes W Breimer AY van Rijn BB Koenen SV Mol BW Franx A de Groot CJ Koster MP 2015中华高血压杂志2015,23,2:5
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