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| 1 | Bottom water temperature measurements in the South China Sea,eastern Indian Ocean and western Pacific Ocean显示文摘文章报道了一批新的海底底水温度(BWT)数据,其中南海(SCS)158个站位、东印度洋(EIO)30个站位及西太平洋(WPO)37个站位。基于这批新的BWT数据,获得南海和西太平洋海域底水温度与水深经验关系,可为地球物理和物理海洋提供准确、可靠的海底温度边界。这将有助于海底油气资源调查与评估。同时,这批实测数据表明:1)水深超过3500m的海域,其底水温度在南海约为2.47℃,比东印度洋(~1.34℃)和西太平洋(~1.60℃)稍微偏高。这与大洋传送带模式所预测的情况比较吻合。该模式认为:低温高盐的海水,从北大西洋格陵兰岛和冰岛附近海域下沉到深层,然后向南流动,再与南极洲周围海域的低温高盐海水一同向北进入印度洋和太平洋。而南海是一个相对比较封闭的热带边缘海,其内部海水与印度洋和菲律宾海交换有限,导致海水温度整体高于印度洋和太平洋。2)台西南盆地水深在2700~3000m的部分站位,其底水温高达约3.00℃,明显高于其周边同水深海域底水温度(平均值约为2.33℃)。这可能是台西南盆地海底水热活动导致的结果。3)在东印度洋和西太平洋水深超过4800m海域,底水温度随着水压增大稍有升高,其升高率分别为10.6mK·MPa^(-1)和12.0mK·MPa^(-1)。这与理论估算的深层底水绝热压力温度梯度范围较为吻合。这也意味着东印度洋和西太平洋深层底水,主要由绝热自压作用导致其温度随着深度的增大而升高。 | YANG Xiaoqiu SHI Xiaobin ZHAO Junfeng YU Chuanhai GAO Hongfang CHEN Aihua LU Yuanzheng CEN Xianrong LIN Weiren ZENG Xin XU Hehua REN Ziqiang ZHOU Shengqi XU Ziying SUN Jinlong KAMIYA Nana LIN Jian | 2018 | 热带海洋学报2018，37，5： | 8 |
| 2 | Reduction in Intrahepatic cccDNA and Integration of HBV in Chronic Hepatitis B Patients with a Functional Cure显示文摘Background and Aims:Functional cure(FC)is characterized by the clearance of the hepatitis B surface antigen from the serum of patients with chronic hepatitis B(CHB).However,the level of intrahepatic covalently closed circular DNA(cccDNA)and hepatitis B virus(HBV)integration remains unclear.We conducted this study to determine them and reveal their value in the treatment of CHB.Methods:There were two sessions to elucidate the changes in intrahepatic cccDNA and HBV integration after antiviral therapy.In the first session,116 patients were enrolled and divided into FC,non-functional cure(NFC),and CHB groups,including 48 patients with functionally cured CHB,27 with CHB without functional cure after antiviral treatment,and 41 with treatment-naïve CHB.Patients were tested for both intrahepatic cccDNA and other viral markers.All patients in the FC group were followed up for at least 24 weeks to observe relapse.In the second session,another ten patients were included for in-depth whole-genome sequencing to analyze HBV integration.Results:Thirteen patients in the FC group were negative for intrahepatic cccDNA.Intrahepatic cccDNA was much higher in the CHB group compared with the FC group.Seven patients had HBsAg seroreversion,including two with virological relapse.Integration of HBV was detected in one(33.3%)functionally cured patients and in seven(100%)with CHB.28.0%of the HBV breakpoints were assigned in the 1,500 nt to 1,900 nt range of the HBV genome.Conclusions:After achieving an FC,the rate of intrahepatic cccDNA and HBV integration was significantly reduced in patients with CHB.For those patients who cleared intrahepatic cccDNA,the chances of developing virological relapse were even lower. | Weiqiang Gan Na Gao Lin Gu Zhishuo Mo Xiuqing Pang Ziying Lei Zhiliang Gao | 2023 | Journal of Clinical and Translational Hepatology2023，11，2： | 2 |
| 3 | Preparation of titanium dioxide-double-walled carbon nanotubes and its application in flexible dye-sensitized solar cells显示文摘有 20 wt.% 的 DWCNTs/TiO2 的钛 dioxide-double-walled 碳 nanotubes (TiO2-DWCNTs ) 被一个常规大音阶的第五音胶化方法准备。在 TiO2 photoanode 做 TiO2-DWCNTs,一节灵活敏化染料的太阳能电池(DSSC ) 被制作。样品被扫描电子显微镜学描绘, X 光检查衍射(XRD ) , Fourier 变换红外线的光谱学(FTIR ) 吸收,紫外可见的光谱学(UVvis ) 吸收系列,电气化学的阻抗光谱学(EIS ) 技术和光电的测量。它被发现那补充说 TiO2-DWCNTs 的某个数量能高效地减少费用运输的抵抗,改善染料吸附。在一个最佳的条件下面,灵活 DSSC 与 0.50 wt.% TiO2-DWCNTs 包含了完成 3.89% 的 light-to-electric 精力变换效率在下面一 simulate 100mWparency 的太阳的轻照耀吗?? | Cunxi CHENG Jihuai WU Yaoming XIAO Yuan CHEN Haijun YU Ziying TANG Jianming LIN Miaoliang HUANG | 2012 | Frontiers of Optoelectronics2012，5，2： | 1 |
| 4 | Studies on microRNAs that are correlated with the cancer stem cells in chronic myeloid leukemia显示文摘 | Xishan Zhu Ziying Lin Jing Du Xu Zhou Lawei Yang Gang Liu | 2014 | 2014 (1-2)2014，，1： | 1 |
| 5 | Association between the nasopharyngeal microbiome and metabolome in patients with COVID-19显示文摘SARS-CoV-2,the causative agent for COVID-19,infect human mainly via respiratory tract,which is heavily inhabited by local microbiota.However,the interaction between SARS-CoV-2 and nasopharyngeal microbiota,and the association with metabolome has not been well characterized.Here,metabolomic analysis of blood,urine,and nasopharyngeal swabs from a group of COVID-19 and non-COVID-19 patients,and metagenomic analysis of pharyngeal samples were used to identify the key features of COVID-19.Results showed lactic acid,L-proline,and chlorogenic acid methyl ester(CME)were significantly reduced in the sera of COVID-19 patients compared with non-COVID-19 ones.Nasopharyngeal commensal bacteria including Gemella morbillorum,Gemella haemolysans and Leptotrichia hofstadii were notably depleted in the pharynges of COVID-19 patients,while Prevotella histicola,Streptococcus sanguinis,and Veillonella dispar were relatively increased.The abundance of G.haemolysans and L.hofstadii were significantly positively associated with serum CME,which might be an anti-SARS-CoV-2 bacterial metabolite.This study provides important information to explore the linkage between nasopharyngeal microbiota and disease susceptibility.The findings were based on a very limited number of patients enrolled in this study;a larger size of cohort will be appreciated for further investigation. | Jing Liu Sheng Liu Zhao Zhang Xuejun Lee Wenxuan Wu Zhanlian Huang Ziying Lei Wenxiong Xu Dabiao Chen Xing Wu Yang Guo Liang Peng Bingliang Lin Yutian Chong Xiangyu Mou Mang Shi Ping Lan Tao Chen Wenjing Zhao Zhiliang Gao | 2021 | Synthetic and Systems Biotechnology2021，6，3： | 0 |
| 6 | Flexible triboelectric nanogenerator toward ultrahigh-frequency vibration sensing显示文摘Flexible high-frequency vibration sensors are highly desirable in various real-world applications such as structural health monitoring,environmental monitoring,and the internet of things.However,developing a facile and effective method to fabricate vibration sensors simultaneously featuring high vibration frequency response-ability and flexibility remains a grand challenge.Herein,we report a flexible ultrahigh-frequency triboelectric vibration sensor(UTVS)prepared by a layer-particle-layer structure.Owing to the flexibility of the materials(i.e.,polyethylene terephthalate membrane)and the ultrahigh-frequency vibration response-ability of internal microparticles,the flexible UTVS exhibits an enhanced working frequency range of 3–170 kHz,which is much broader than previously reported triboelectric vibration sensors.Moreover,the UTVS can work not only in a flat state but also in a bent state due to its flexibility and the unique layer-particle-layer structural design.The UTVS shows nanometer-level vibration response-ability,omnidirectional response,stability in the temperature range of 10–70°C,good frequency resolution of 0.01 kHz,and excellent performance in burst vibration detection(e.g.,pencil lead break events and impact events from falling steel balls).With a collection of compelling features,the device is successfully demonstrated in vibration monitoring of curved structures(e.g.,real-time water pipeline leak monitoring).Such a flexible ultrahigh-frequency triboelectric vibration sensor holds great potential in a wide range of practical applications,such as communication,health care,and infrastructure monitoring. | Zhiwei Lin Chenchen Sun Gaoqiang Zhang Endong Fan Zhihao Zhou Ziying Shen Jun Yang Mingyang Liu Yushu Xia Shaobo Si Jin Yang | 2022 | Nano Research2022，15，8： | 0 |
| 7 | Recommendation about the perioperative prevention of infection to healthcare workers and the anesthesia management of children with SARS-CoV-2 infection显示文摘Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has spread widely and persistently over 100 countries.New challenges have occurred in the perioperative management of airway and anesthesia in children diagnosed with SARS-CoV-2 infection.According to current publications and to our own experiences in anesthesia management for cases with SARS-CoV-2 suspected,we reviewed concerns about the perioperative prevention of SARS-CoV-2 to medical staff and the anesthesia strategy to the patient. | Jinjin Huang Yaoqin Hu Jiangmei Wang Dongpi Wang Zhirui Zhu Zhiyong Hu Ziying Jin Hongfei Lin Wenfang Huang Weiqing Shen Yilei Jiang Miaofeng Hu Jingzhen Wu Yaojun Suo Qiang Shu | 2020 | World Journal of Pediatric Surgery2020，3，1： | 0 |
| 8 | 8-Oxoguanine DNA glycosylase protects cells from senescence via the p53-p21 pathway显示文摘Cellular senescence is an important factor leading to pulmonary fibrosis.Deficiency of 8-oxoguanine DNA glyco-sylase(OGG1)in mice leads to alleviation of bleomycin(BLM)-induced mouse pulmonary fibrosis,and inhibition of the OGG1 enzyme reduces the epithelial mesenchymal transition(EMT)in lung cells.In the present study,we find decreased expression of OGG1 in aged mice and BLM-induced cell senescence.In addition,a decrease in OGG1 expression results in cell senescence,such as increases in the percentage of SA-β-gal-positive cells,and in the p21 and p-H2AX protein levels in response to BLM in lung cells.Furthermore,OGG1 promotes cell transformation in A549 cells in the presence of BLM.We also find that OGG1 siRNA impedes cell cycle progression and inhibits the levels of telomerase reverse transcriptase(TERT)and LaminB1 in BLM-treated lung cells.The increase in OGG1 expression results in the opposite phenomenon.The mRNA levels of senescence-associated secretory phenotype(SASP)components,including IL-1α,IL-1β,IL-6,IL-8,CXCL1/CXCL2,and MMP-3,in the absence of OGG1 are obviously increased in A549 cells treated with BLM.Interestingly,we demonstrate that OGG1 binds to p53 to inhibit the activation of p53 and that silencing of p53 reverses the inhibition of OGG1 on senescence in lung cells.Ad-ditionally,the augmented cell senescence is shown in vivo in OGG1-deficient mice.Overall,we provide direct evidence in vivo and in vitro that OGG1 plays an important role in protecting tissue cells against aging associated withthep53pathway. | Shenglan Gao Lujun Chen Ziying Lin Zhiliang Xu Yahong Wang Huayu Ling Zijun Wu Yu Yin Weimin Yao Keng Wu Gang Liu | 2024 | Acta Biochimica et Biophysica Sinica2024，56，2： | 0 |
| 9 | Unraveling the Fundamental Mechanism of Interface Conductive Network Influence on the Fast‑Charging Performance of SiO‑Based Anode for Lithium‑Ion Batteries显示文摘Progress in the fast charging of high-capacity silicon monoxide(SiO)-based anode is currently hindered by insufficient conductivity and notable volume expansion.The construction of an interface conductive network effectively addresses the aforementioned problems;however,the impact of its quality on lithium-ion transfer and structure durability is yet to be explored.Herein,the influence of an interface conductive network on ionic transport and mechanical stability under fast charging is explored for the first time.2D modeling simulation and Cryo-transmission electron microscopy precisely reveal the mitigation of interface polarization owing to a higher fraction of conductive inorganic species formation in bilayer solid electrolyte interphase is mainly responsible for a linear decrease in ionic diffusion energy barrier.Furthermore,atomic force microscopy and Raman shift exhibit substantial stress dissipation generated by a complete conductive network,which is critical to the linear reduction of electrode residual stress.This study provides insights into the rational design of optimized interface SiO-based anodes with reinforced fast-charging performance. | Ruirui Zhang Zhexi Xiao Zhenkang Lin Xinghao Yan Ziying He Hairong Jiang Zhou Yang Xilai Jia Fei Wei | 2024 | Nano-Micro Letters2024，16，3： | 0 |
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