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| 1 | Epidemiology of varicocele显示文摘精索静脉曲张是在繁殖的药实践的一个普通问题。精索静脉曲张与主要不孕在 15% 健康的人被识别。精索静脉曲张的准确 pathophysiology 很好没被理解,特别关于它男不孕上的效果。我们进行了在一般人口并且在与不孕介绍的人评估精索静脉曲张的传染病学的研究的系统的评论。在这篇文章,我们识别了一些能影响精索静脉曲张的流行病学的方面的因素。我们也认识到精索静脉曲张传染病学仍然保持不完全地理解,并且有需要让设计得好的、大规模研究充分定义这个条件的流行病学的方面。 | Bader Alsaikhan Khalid Alrabeeah Guila Delouya Armand Zini | 2016 | Asian Journal of Andrology2016,18,2: | 44 |
| 2 | A systematic review and meta-analysis to determine the effect of sperm DNA damage on in vitro fertilization and intracytoplasmic sperm injection outcome显示文摘精子 DNA 损坏在不肥沃的人之中是流行的并且被知道影响自然复制。然而,帮助繁殖结果上的精子 DNA 损坏的影响仍然保持争论。这里,我们在精子 DNA 损坏上进行了研究的元分析(由 SCSA, TUNEL, SCD,或彗星试金估计了) 并且在从 MEDLINE, EMBASE,和 PUBMED 数据库的 IVF 或 ICSI 处理以后的临床的怀孕寻找这分析。我们识别了 41 篇文章(与 56 研究的一个总数) 包括 16, IVF 学习, 24 ICSI 研究,并且 16 混合了(IVF + ICSI ) 学习。这些研究测量了 DNA 损坏(由四试金之一:23 SCSA, 18 TUNEL, 8 SCD,和 7 彗星) 并且包括了 8068 个处理周期(3734 IVF, 2282 ICSI,和 2052 混合 IVF + ICSI ) 的一个总数。联合或 1.68 (95% CI:1.49-1.89;P <0.0001 ) 显示那精子 DNA 损坏影响临床的怀孕追随者 IVF 或 ICSI 处理。另外,联合或 IVF 的估计(16 估计,或 = 1.65;95% CI:1.34-2.04;P <0.0001 ) , ICSI (24 估计,或 = 1.31;95% CI:1.08-1.59;P = 0.0068 ) ,并且混合 IVF + ICSI 学习(16 估计,或 = 2.37;95% CI:1.89-2.97;P <0.0001 ) 也是统计上重要的。在建议精子 DNA 损坏在临床的怀孕追随者 IVF 或 ICSI 处理上有否定效果的存在文学有足够的证据。 | Luke Simon Armand Zini Alina Dyachenko Antonio Ciampi Douglas T Carrell | 2017 | Asian Journal of Andrology2017,19,1: | 38 |
| 3 | 抗氧化剂可以治疗男性不育吗?显示文摘不育男性精液中活性氧(ROS)的浓度高于正常男性。精液中ROS水平的升高会导致精于功能障碍,精子DNA损伤,降低男性的生殖能力。这一现象启发临床医生通过补充抗氧化剂来治疗男性不育。本综述旨在探讨抗氧化剂治疗男性不育的基本原理,并通过数据分析评价饮食及体外抗氧化剂的补充对精子功能和DNA损伤的修复效果。迄今为止,多数临床研究表明饮食中补充抗氧化剂有益于精子功能及DNA完整性方面的改善。但是,膳食抗氧化剂的作用机制以及最佳膳食补充方案尚未建立。此外,多数临床研究的样本较少,而且很少有人评价怀孕率。多数研究表明体外抗氧化补充剂在保护精予免受外源氧化剂的损伤方面是有效的,然而,这些抗氧化剂在保护精子免受内源性活性氧、轻微的精子处理及冷冻保存的损伤方面尚无定论。 | Armand Zini Naif AI-Hathal | 2011 | Asian Journal of Andrology2011,13,3: | 6 |
| 4 | Use of testicular sperm in couples with SCSA-defined high sperm DNA fragmentation and failed intracytoplasmic sperm injection using ejaculated sperm显示文摘Sperm DNA fragmentation(SDF)has been linked with male infertility,and previous studies suggest that SDF can have negative influence on pregnancy outcomes with assisted reproduction.We performed a retrospective review of consecutive couples with a high SDF level that had intracytoplasmic sperm injection(ICSI)using testicular sperm(T-ICSI).We compared the T-ICSI outcomes to that of two control groups:87 couples with failed first ICSI cycle and who had a second ICSI cycle using ejaculated sperm(Ej-ICSI),and 48 consecutive couples with high sperm chromatin structure assay(SCSA)-defined SDF(>15%)that underwent an ICSI cycle using ejaculated sperm after one or more failed ICSI cycles(Ej-ICSI-high SDF).The mean number of oocytes that were retrieved and the total number of embryos were not different among the three groups.The mean number of transferred embryos in the T-ICSI group was higher than the Ej-ICSI group but not significantly different than the Ej-ICSI-high SDF group(1.4,1.2,and 1.3,respectively,P<0.05).Clinical pregnancy rate in the T-ICSI group was not significantly different than the Ej-ICSI and Ej-ICSI-high SDF groups(48.6%,48.2%,and 38.7%,respectively,P>0.05).No significant difference was found in live birth rate when comparing T-ICSI to Ej-ICSI and Ej-ICSI-high SDF groups.The results suggest that pregnancy outcomes and live birth rates with T-ICSI are not significantly superior to Ej-ICSI in patients with an elevated SCSA-defined sperm DNA fragmentation and prior ICSI failure(s). | Mohannad Alharbi Fadl Hamouche Simon Phillips Jacques Isaac Kadoch Armand Zini | 2020 | Asian Journal of Andrology2020,22,4: | 4 |
| 5 | Sperm nuclear histone H2B: correlation with sperm DNA denaturation and DNA stainability显示文摘瞄准:检验在精子 DNA 损坏和精子之间的关系原子嘘染色的(H2B ) 。方法:我们从 14 连续 asthenoteratozoospermic 评估了精子样品不肥沃的人和六连续肥沃的控制。精子原子嘘染色的(H2B ) 和精子染色质正直(由精子染色质结构试金估计了并且表示了使用(i) DNA 破碎索引的百分比[% DFI ] 并且(i i ) 高 DNA 污点能力[% HDS )]) 被评估。结果:Histone H2B 免疫细胞化学表明了二个原子染色模式:(i) 焦点的有小斑点的染色;并且(i i ) 扩散染色。不肥沃的人有展出弥漫的 H2B 染色比的精子的一个更高吝啬的百分比做了肥沃的人(7.7% ± 4.6%vs .1.6% ± 1.2% ,分别地 P <
0.01 ) 。我们观察了在精子的比例之间的重要关系与弥漫原子嘘一染色和两精子 % DFI (r= 0.63, P <
0.01 ) 并且精子 % HDS (r= 0.63, P <
0.01 ) 。结论:数据证明不肥沃的人有精子的一个更高的比例与弥漫嘘一 H2B 与做肥沃的人并且建议精子 DNA 损坏力量比,至少部分地,由于反常地高嘘一个 H2B 层次。 | Armand Zini Xiaoyang Zhang Maria San Gabriel | 2008 | Asian Journal of Andrology2008,10,6: | 3 |
| 6 | The new 6^(th) edition of the WHO Laboratory Manualfor the Examination and Processing of HumanSemen: is it a step toward better standard operatingprocedure?显示文摘Semen analysis(SA)remains the cornerstone of male infertility evaluation and should ideally be performed by an accredited andrology laboratory or in vitro fertilization(IVF)clinics based on the standards defined by the World Health Organization(WHO)for the Examination and Processing of Human Semen and in accordance with the International Organization for Standardization’s Basic Semen Examination on Specification and Test Methods. | Eric Chung Mohamed Arafa Florence Boitrelle Hussein Kandil Ralf Henkel Ramadan Saleh Rupin Shah Paraskevi Vogiatzi Armand Zini Ashok Agarwal | 2022 | Asian Journal of Andrology2022,24,2: | 2 |
| 7 | Effects of resveratrol on the rat brain respiratory chain显示文摘 | Morin C Bertelli A | 1999 | Drugs Exp Clin Res1999,25,: | 1 |
| 8 | Immunohistichemical localization of endothelial nitric oxide synthase in human testis,epididymis,and vas deferens suggests a possible role for nitric oxide in spermatogenesis,sperm maturation,and programmed cell death 显示文摘 | Zini A O'Bryan M K Magid M S etal | 1996 | Bio Reprod1996,55,: | 1 |
| 9 | Nitric oxide synthase activi ty in human seminal plasma 显示文摘 | Zini A O'Bryan M K Schlegel P N | 2001 | Urology2001,58,1: | 1 |
| 10 | Dynamic analysis of a multi-shaft helical gear transmission by finite elements: model and experiment 显示文摘 | Kubur M Kahraman A Zini D M | 2004 | Transactions of the ASME2004,126,: | 1 |
| 11 | Petrous bonc cholesteatoma显示文摘 | Sanna M Zini C Gamoletti R | 1993 | Skull Base Surg1993,3,4: | 1 |
| 12 | Sperm DNA damage is associated with an increased risk of pregnancy loss after IVF and ICSI:systematic review and meta-analysis显示文摘 | Zini A Boman JM Belzile E | 2008 | Hum Reprod2008,23,12: | 1 |
| 13 | Effect of microsurgical varieoeeleetomy on human sperm chromatin and DNA integri- ty: a prospective trial显示文摘 | Zini A Azhar R Baazeem A | 2011 | Int J Androl2011,34,1: | 1 |
| 14 | Diagnostic performance of 64-MDCT and 1.5-T MRI with highresolution sequences in the T staging of gastric cancer: a comparative analysis with histopathology显示文摘 | M. Anzidei A. Napoli F. Zaccagna P. Paolo C. Zini B. Cavallo Marincola D. Geiger C. Catalano R. Passariello | 2009 | La radiologia medica2009,,7: | 1 |
| 15 | Rilevazione della flora microbica dimostie vini显示文摘 | CAVAZZA A GRANDO M S ZINI C | 1992 | Vignevini1992,9,: | 1 |
| 16 | Prevalence of abnormal sperm DNA denaturation in fertile and infertile men显示文摘 | Zini A Fischer MA Sharir S | 2002 | Urology2002,60,6: | 1 |
| 17 | Low levels of nitric oxide promote human sperm capacitation in vitro 显示文摘 | Zini A De Lamirande E | 1995 | J Androl1995,16,5: | 1 |
| 18 | Anti-sperm antibodies are not associated with pregnancy rates after IVF and ICSI:systematic review and meta-analysis显示文摘 | Zini A Fahmy N Belzile E Garcia A | 2011 | Hum Reprod2011,26,6: | 1 |
| 19 | Effects of resveratrol on the rat brain respiratory chain 显示文摘 | Zini R | 1999 | Drugs Exp Clin Res1999,25,23: | 1 |
| 20 | Biological variability of sperm DNA denaturation in infertile men显示文摘 | Zini A Kamal K Phan D et a l | 2001 | Urology2001,58,2: | 1 |