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1Celiac disease: Alternatives to a gluten free diet显示文摘Celiac disease is a chronic inflammatory disorder of the small intestine caused by the ingestion of gluten or related rye and barley proteins. At present, the only available treatment is a strict gluten-exclusion diet. However, recent understanding of the molecular basis for this disorder has improved and enabled the identif ication of targets for new therapies. This article aims to critically summarize these recent studies.Fabiana Zingone Pietro Capone Carolina Ciacci 2010World Journal of Gastrointestinal Pharmacology and Therapeutics2010,1,1:3
2Human leukocyte antigen DQ2/8 prevalence in non-celiac patients with gastrointestinal diseases显示文摘AIM: To investigate the prevalence of human leukocyte antigen (HLA) DQ2/8 alleles in Southern Italians with liver and gastrointestinal (GI) diseases outside of celiac disease. METHODS: HLA DQ2/8 status was assessed in 443 patients from three ambulatory gastroenterology clinics in Southern Italy (University of Federico Ⅱ, Naples, Loreto Crispi Hospital, Ruggi D'Aragona Hospital, Salerno). Patients were grouped based on disease status [pre-post transplant liver disease, esophageal/gastric organic and functional diseases, irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD)] and DQ2/8 alleles, which correspond to a celiac disease genetic risk gradient. Subject allele frequencies were compared to healthy Italian controls. RESULTS: One hundred and ninety-six out of four hundred and forty-three (44.2%) subjects, median age 56 years and 42.6% female, were DQ2/8 positive. When stratifying by disease we found that 86/188 (45.7%) patients with liver disease were HLA DQ2/8 positive, 39/73 (53.4%) with functional upper GI diseases and 19/41 (46.3%) with organic upper GI diseases were positive. Furthermore, 38/105 (36.2%) patients with IBS and 14/36 (38.9%) with IBD were HLA DQ2/8 positive (P = 0.21). Compared to healthy controls those with functional upper GI diseases disorders had a 1.8 times higher odds of DQ2/8 positivity. Those with liver disease had 1.3 times the odds, albeit not statistically significant, ofDQ2/8 positivity. Both those with IBS and IBD had a lower odds of DQ2/8 positivity compared to healthy controls. CONCLUSION: The proportion of individuals HLA DQ2/8 positive is higher in those with liver/upper functional GI disease and lower in IBS/IBD as compared to general population estimates.Daniel DiGiacomo Antonella Santonicola Fabiana Zingone Edoardo Troncone Maria Cristina Caria Patrizia Borgheresi Gianpaolo Parrilli Carolina Ciacci 2013World Journal of Gastroenterology2013,19,16:2
3The diversity of harmful algal blooms:a challenge for science and management显示文摘ZINGONE A ENEVOLDSEN H 2002Ocean & Coastal Management2002,43,89:1
4Early and late outcomes of cardiac surgery in octogenarians 显示文摘Zingone B Gatti G Rauber E 2009Ann Thorac Surg2009,87,1:1
5CD69-triggered ERK activation and function are negatively regulated by CD94/NKG2-A inhibitory显示文摘Zingon A Palmieri G Morrone S 2000Eur J Immunol2000,30,2:1
6CD69-triggered ERK activation and function are negatively regulated by CD94/NKG2-A inhibitory receptor显示文摘Zingon A Palmieri G Morrone S 2000Eur J Immunol2000,30,2:1
7Deletion polymorphism in the gene for angioten- sin converting enzyme is associated with elevated fasting blood glucose levels 显示文摘Zingone A 1994Hum Genet1994,94,20:1
8Metalloproteinases-2, -9 and TIMP-1 expression in stable and unstable coronary plaques undergoing PCI显示文摘Nicola Fiotti Nicola Altamura Claudio Orlando Lisa Simi Bernhard Reimers Pietro Pascotto Bartolo Zingone Andrea Pascotto Mario Serio Gianfranco Guarnieri Carlo Giansante 2007International Journal of Cardiology2007,,3:1
9Dissolution rates of different drugs from solid dispersions with Eudragit RS 显示文摘Filippis PD Zingone G Gibellini M 1995Eur J Pharm Sci1995,3,:1
10Early and late outcomes of cardiac surgery in octogenarians显示文摘Zingone B Gatti G Rauber E 0,,01:1
11Deflections of beams with varying rectangular cross section显示文摘ROMANO F ZINGONE G 1992Journal of Engineering Mechanics1992,118,10:1
12Early and late outcomes of cardiac surgery in octogenarians 显示文摘Zingone B Gatti G Rauber E 2009Ann Thorac Surg2009,87,1:1
13Early and late outcomes of cardiac surgery in octogenarians显示文摘Zingone B Gatti G Rauber E 2009Ann Thorac Surg2009,87,1:1
14Early and late outcomes of cardiac surgery in octogenarians显示文摘Zingone B Gatti G Rauber E 2009Ann Thorac Surg2009,87,1:1
15Comparing team-based and mixed active-learning methods in an ambulatory care elective course 显示文摘Zingone MM Franks AS Guirguis AB et 81 2010Am J Pharm Educ2010,74,9:1
16The diversity of harmful algal blooms:a challenge for science and management显示文摘Zingone A Enevoldsen H O 0,,:1
17CD69-triggered ERK activation and function are negatively regulated by CD94/NKG2-A inhibitory显示文摘Zingon A Palmieri G Morrone S 2000Eur J Immunol2000,30,2:1
18Early and late outcomes of cardiac surgery in octogenarians显示文摘Zingone B Gatti G Rauber E 2009Ann Thorac Surg2009,87,1:1
19Behavior of fiber reinforced concrete-filled tubular columns in compression 显示文摘Campione G Mendola L L Sanpaolesi L Scibilia N Zingone G 2002Materials and Structures2002,35,:1
20Impaired coronary flow reserve with aortic stenosis despite aortic valve replacement显示文摘Zingone B 0,,:1
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