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| 1 | Isolation of the mucilages from Hibiscus rosasinensis linn.and Okra(Abelmoschus esculentus linn.) and studies of the binding effects of the mucilages显示文摘Objective:To isolate and evaluate comparatively the binding efficacy of the mucilages obtained from the plants of Hibiscus rosasinensis and Okra(Abelmoschus esculentus).Methods:Extraction of mucilages from the leaves of Hibiscus and pods of Okra(Ladies finger) was carried out by a cold maceration process.The extracted mucilages were subjected to various physicochemical properties for its suitability as an excipient in the formulation of tablet dosage form.Different concentrations(10,8,5,2 and 1%w/v) of binder solutions of Hibiscus and Okra were used for the formulation of tablets and the formulated tablets were evaluated by studying the standard parameters like diameter,thickness,weight variation,hardness,friability,disintegration and in vitro dissolution.Stability studies of the formulated tablets were conducted for four weeks. Results:The formulated tablets prepared using the mucilages of both Hibiscus and Okra had good appearance.The in vitro drug release profile of the tablets prepared using Okra mucilage had an optimum of 90%at a mucilage concentration of 1%w/v concentration mucilage itself within 4 h.Conclusions:According to the observations,the lower concentration levels of Okra can be used as an alternative binder to starch.The higher concentration levels of Okra mucilage show a slow and sustained release,and can be considered as an alternative natural excipient in the modified drug delivery systems.At the same time,the above natural excipient of Hibiscus mucilage could be used as a platform for prolonged release if its binder concentrations are increased. | Ameena K Dilip C Saraswathi R Krishnan PN Sankar C Simi SP | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，7： | 8 |
| 2 | Transcranial direct current stimulation in psychiatric disorders显示文摘The interest in non-invasive brain stimulation techniques is increasing in recent years. Among these techniques, transcranial direct current stimulation(t DCS) has been the subject of great interest among researchers because of its easiness to use, low cost, benign profile of side effects and encouraging results of research in the field. This interest has generated several studies and randomized clinical trials, particularly in psychiatry. In this review, we provide a summary of the development of the technique and its mechanism of action as well as a review of the methodological aspects of randomized clinical trials in psychiatry, including studies in affective disorders, schizophrenia, obsessive compulsive disorder, child psychiatry and substance use disorder. Finally,we provide an overview of t DCS use in cognitive enhancement as well as a discussion regarding its clinical use and regulatory and ethical issues. Although many promising results regarding t DCS efficacy were described, the total number of studies is still low, highlighting the need of further studies aiming to replicate these findings in larger samples as to provide a definite picture regarding t DCS efficacy in psychiatry. | Gabriel Tortella Roberta Casati Luana V M Aparicio Antonio Mantovani Natasha Senco Giordano D’Urso Jerome Brunelin Fabiana Guarienti Priscila Mara Lorencini Selingardi Débora Muszkat Bernardo de Sampaio Pereira Junior Leandro Valiengo Adriano H Moffa Marcel Simis Lucas Borrione André R Brunoni | 2015 | World Journal of Psychiatry2015，5，1： | 6 |
| 3 | The impact of performance-based compensation on misreporting显示文摘 | Natasha Burns Simi Kedia | 2005 | Journal of Financial Economics2005，，1： | 4 |
| 4 | Streptomyces sp. RP1A-12 mediated control of peanut stem rot caused by Sclerotium rolfsii显示文摘Sclerotium rolfsii Sacc. is a destructive soilborne fungal pathogen with a wide host range that includes peanuts. Biological control offers an interesting alternative to fungicides for sustainable management of soilborne diseases. The current investigation is aimed at evaluating one potential biocontrol agent Streptomyces sp. RP1 A-12 for growth promotion and the management of peanut stem rot disease caused by S. rolfsii under field conditions. Preliminary studies conducted under in vitro and the greenhouse conditions showed promising results against the stem rot pathogen. Further in vitro and pot experiments conducted to assess Streptomyces sp. RP1 A-12 for its growth promoting abilities using whole organisms have shown an increase in seed germination, root and shoot length. Other parameters like nodule number and plant biomass were also significantly increased over control treatments indicating that the test bioagent possesses growth promoting abilities along with disease suppression capabilities. Subsequently field studies were carried out for two consecutive rainy seasons. The bioagent was applied as whole organism and partially purified crude metabolites. Results indicate the bioagent reduced stem rot disease incidence by 64–67% and 22–49% respectively in two field trials conducted with notable increase in yield. Partially purified Streptomyces sp. RP1 A-12 metabolites exhibited an even greater effect in reducing the incidence and severity of stem rot compared to the pathogen inoculated control. | Simi Jacob Ramgopal Rao Sajjalaguddam Hari Kishan Sudini | 2018 | Journal of Integrative Agriculture2018，17，4： | 4 |
| 5 | Colonoscopy and the role of music therapy: How to go about an ideal protocol?显示文摘TO THE EDITOR We read with great interest the two articles in the December 2006 issue of your esteemed journal on the utility of music therapy in the performance of colonoscopy[1,2]. The role of non-pharmacological or cognitive behavioral | R Harikumar Simi Kumar | 2007 | World Journal of Gastroenterology2007，13，23： | 3 |
| 6 | Institutional ownership and monitoring: Evidence from financial misreporting显示文摘 | Natasha Burns Simi Kedia Marc Lipson | 2010 | Journal of Corporate Finance2010，，4： | 2 |
| 7 | Peltzman effect and resurgence of COVID-19 in India显示文摘With a daily rise of over 400000 cases,the deadly COVID-19 wave has gripped India with grim milestones.India’s test positivity rate(TPR)was 16%with 1356133 tests[1,2](Figure 1).The number is still steeply climbing and has burdened the already overwhelmed health system.A frightening situation of lack of availability of hospital beds and critical care units has been witnessed in several states in recent days. | Simi Thankappan Sherin Nedumpillil | 2021 | Asian Pacific Journal of Tropical Medicine2021，14，5： | 1 |
| 8 | Influence of phytoplankton pigment composition on remote sensing of cyanobacterial biomass 显示文摘 | Simis S G H Ruiz-Verdu A Dominguez-Gomez J A | 2007 | Remote Sensing of Environment2007，106，： | 1 |
| 9 | Peritumoral brain edema in benign meningiomas: correlation with clinical, radiologic, and surgical factors and possible role on recurrence 显示文摘 | Simis A Pires de Agniar PH Leite CC | 2008 | Surg Neurol2008，70，5： | 1 |
| 10 | Radiofrequency ablation for Barrett's esophagus high-volume center initial results显示文摘 | Simi A Skrobi O Micev M | 2012 | Acta Chir Ingosl2012，59，1： | 1 |
| 11 | Hydrophobic grafted and cross-linked starch nanoparticles for drug delivery显示文摘 | C K Simi T Emilia Abraham | 2007 | Bioprocess and Biosystems Engi- neering2007，30，： | 1 |
| 12 | Multi-type childhood abuse, strategies of coping, and psychological adaptations in young adults 显示文摘 | SESAR K SIMIe N BARISIe M | 2010 | Croatian Med J2010，51，5： | 1 |
| 13 | Signless Laplaeians of finite graphs显示文摘 | Cvetkovie D Rowlinson P Simie S K | 2007 | Linear Algebra Appl2007，432，： | 1 |
| 14 | European risk factors' model to predict hospitalization of pre- mature infants bom 33- 35 weeks' gestational age with res- piratory syncytial virus: validation with Italian data显示文摘 | Simies E A F Carbonell - Estrany X Fullarton J R | 2011 | Jour- nal of Maternal - Fetal and Neonatal Medicine2011，24，1： | 1 |
| 15 | Varia- tional problems with fractional derivatives: invariance conditions and noether's theorem 显示文摘 | ATANACKOVI (~ T M KONJIK S SIMI (~ S | 2009 | Nonlinear Analy- sis: Theory Methods & Applications2009，71，56： | 1 |
| 16 | Clinical implementation of noninvasive prenatal testing among maternal fetal medicine specialists显示文摘 | Haymon L Simi E Moyer K | 2014 | Prenat Diagn2014，34，5： | 1 |
| 17 | Effect of amount and types of dietary fat on intestinal bacterial 7 alpha-dehydroxylase and phosphate-dylinositol-specific phos pholipase C and colonic mucosal diacylglycerol kinase and PKC activities during stages of colon tumor promotion显示文摘 | Reddy BS Simi B Patel N | 1996 | Cancer Res1996，56，10： | 1 |
| 18 | Peritumoral brain edema in benign meningiomas: correlation with clinical, radiologic, and surgical factors and possible role on recurrence显示文摘 | Simis A Pires de Aguiar PH Leite CC | 2008 | Surg Neurol2008，70，： | 1 |
| 19 | Diagnosis and treatment of haemorrhoids in the elderly: results from 291 patients显示文摘 | L. Navarra R. Pietroletti G. Maggi S. Leardi M. Simi | 1999 | Techniques in Coloproctology1999，，3： | 1 |
| 20 | Autostereoscopie three-dimensional viewer evaluation through comparison with conventional interfaces in laparoseopie surgery 显示文摘 | Silvestri M Simi M Cavallotti C | 2011 | Surg Innov2011，18，3： | 1 |
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