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| 1 | Materials Experiment on Tiangong-2 Space Laboratory显示文摘During the China's Tiangong-2(TG-2) flight mission, the experiments of 18 kinds of material samples were conducted in space by using a Multiple Materials Processing Furnace(MMPF) mounted in the orbital module of the TG-2 space laboratory. After the experiments of 12 kinds of samples of the first and second batches were completed successfully, astronauts packed and brought them back to the ground by ShenzhouII spacecraft. By studying processing and formation on semiconductor and optoelectronics materials, metal alloys and metastable materials, functional single-crystal, micro-and nano-composite materials encapsulated in sample ampoules both in space and on Earth, we expect to explore some physical and chemical processes and mechanism of the materials formation that are normally obscured and therefore are difficult to study quantitatively on the ground due to the gravity-induced convection, to obtain the processing and synthesis technology for preparing high quality materials, and lead to the improvement and development of materials processing techniques on Earth, and also develop the experiment device and comprehensive ability for materials experiment in microgravity environment. This report briefly introduces the main points of each research work and preliminary comparative analysis results of 12 samples carried out by scientists undertaking research task. | LI Xiangyang LU Ye MENG Xiangjian WANG Jianlu WANG Reng CHEN Lidong HUA Zile LI Xiaoya SHI Jianlin LIU Jinfeng XU Guisheng WEI Bingbo XIE Wenjun YIN Zhigang ZHANG Xingwang JIANG Hongxiang LI Hong LUO Xinghong ZHANG Haifeng ZHAO Jiuzhou WANG Binbin PAN Mingxiang | 2018 | 空间科学学报2018，38，5： | 4 |
| 2 | Research on Pathways of How Digital Transformation Affects the Business Performance of MEEC Enterprises in Chengdu显示文摘This paper aims to examine the impact of digital transformations on the business performance of the meetings,expositions,events,and conventions(MEEC)industry in Chengdu by conducting an empirical analysis of 68 MEEC enterprises in the city.The study employed the fuzzy-set qualitative comparative analysis(fsQCA)method to explore the pathways and factors involved.Drawing on the theory of synergetics,nine condition variables were carefully selected from four dimensions:digital technologies,digital strategy,digital infrastructure,and digital innovation.The findings revealed that digital transformations were an intricate systematic process,whereby a single factor alone did not serve as a necessary condition for MEEC enterprises to achieve high business performance.The analysis identified five distinct pathways that would lead to high performance,which can be categorized into three distinct models:the“organization-human resources”dominated model,the“human resources-infrastructure”driven model,and the multi-factor coordination model.The analysis also identified two pathways that would result in low performance,categorized as the“basic condition absent”model.Notably,there was substantial heterogeneity observed in the configurational pathways in terms of the magnitude of the impact of digital transformation on business performance across MEEC enterprises of different sizes.This paper suggests that the government should assume the role of a platform,providing policy and financial support to MEEC enterprises to help guide them through the process of digital transformation and that MEEC enterprises themselves should seize the opportunities arising from digital transformation to strengthen their digital infrastructure construction,human resources development,and innovation in brand building.This study presents empirical evidence that contributes to the understanding of the transformation process of MEEC enterprises within the digital economy era,as well as valuable insights into understanding the channels and internal conditions involved in digital transformations. | Zhu Yurong Luo Ziling | 2024 | Contemporary Social Sciences2024，9，1： | 0 |
| 3 | Chaperone-mediated Autophagy Regulates Cell Growth by Targeting SMAD3 in Glioma显示文摘Previous studies suggest that the reduction of SMAD3(mothers against decapentaplegic homolog 3)has a great impact on tumor development,but its exact pathological function remains unclear.In this study,we found that the protein level of SMAD3 was greatly reduced in human-grade IV glioblastoma tissues,in which LAMP2A(lysosome-associated membrane protein type 2A)was significantly up-regulated.LAMP2A is a key ratelimiting protein of chaperone-mediated autophagy(CMA),a lysosome pathway of protein degradation that is activated in glioma.We carefully analyzed the amino-acid sequence of SMAD3 and found that it contained a pentapeptide motif biochemically related to KFERQ,which has been proposed to be a targeting sequence for CMA.In vitro,we confirmed that SMAD3 was degraded in either serum-free or KFERQ motif deleted condition,which was regulated by LAMP2A and interacted with HSC70(heat shock cognate 71 kDa protein).Using isolated lysosomes,amino-acid residues 75 and 128 of SMAD3 were found to be of importance for this process,which affected the CMA pathway in which SMAD3 was involved.Similarly,down-regulating SMAD3 or up-regulating LAMP2A in cultured glioma cells enhanced their proliferation and invasion.Taken together,these results suggest that excessive activation of CMA regulates glioma cell growth by promoting the degradation of SMAD3.Therefore,targeting the SMAD3-LAMP2Amediated CMA-lysosome pathway may be a promising approach in anti-cancer therapy. | Hanqun Liu Yuxuan Yong Xingjian Li Panghai Ye Kai Tao Guoyou Peng Mingshu Mo Wenyuan Guo Xiang Chen Yangfu Luo Yuwan Lin Jiewen Qiu Ziling Zhang Liuyan Ding Miaomiao Zhou Xinling Yang Lin Lu Qian Yang Pingyi Xu | 2022 | Neuroscience Bulletin2022，38，6： | 0 |
| 4 | Impact of Geographical Environment on British Landscape Garden Design显示文摘The study attempts to analyze the regional cultural characteristics of Britain under the unique geographical environment by taking the development process and characteristics of British landscape garden as the research object.British culture is an important carrier of British landscape garden culture,and the impact of the unique culture of“the empire on which the sun never sets”on formation and development,formal characteristics,temperament and connotation of landscape garden is discussed. | LUO Fuyuan LAI Ziling | 2020 | Journal of Landscape Research2020，12，5： | 0 |
| 5 | A self-powered ultraviolet photodetector with van der Waals Schottky junction based on TiO_(2) nanorod arrays/Au-modulated V2CTx MXene显示文摘A self-powered ultraviolet photodetector(UV PD)with van der Waals(vdW)Schottky junction based on TiO_(2) nanorod arrays/Au-modulated V2 CTx MXene is reported.The Schottky junction enables the device to operate in self-powered mode.The dangling bond-free surface of V2 CTx MXene reduces the charge recombination at the junction interface.Meanwhile,V2 CTx MXene,with the work function(WF)increasing to 5.35 eV,forms a hole transport layer by contacting with Au electrode,which facilitates the carrier extraction.The electron lifetime in the device has prolonged to 8.95μs.As a result,the responsivity and detectivity of the PD have achieved 28 mA/W and 1.2×10^(11) cm Hz1/2/W(340 nm,65 mW/cm2,0 V),respectively.In addition,the presence of the Au electrode prevents the vanadium from coming into contact with oxygen and oxidizing,preserving the properties of the V2 CTx films.After 180 days of exposure to the atmosphere,the device performance remained at a particularly high level,indicating enhanced durability.This work points out an effective approach to modulate the properties of V2 CTx to obtain the high performance and stability of the UV PD. | Guangcan Luo Ziling Zhang Yabing Wang Qun Deng Shengtao Pan Tengfei Wang Qinghong Li Kaixiang Liu Pengfei Kong Jing Zhang Shengyun Luo Hong Lin | 2023 | Journal of Materials Science & Technology2023，，25： | 0 |
| 6 | Decellularized Extracellular Matrix Containing Electrospun Fibers for Nerve Regeneration:A Comparison Between Core–Shell Structured and Preblended Composites显示文摘Advanced biomaterial-based strategies for treatment of peripheral nerve injury require precise control over both topological and biological cues for facilitating rapid and directed nerve regeneration.As a highly bioactive and tissue-specifc natural material,decellularized extracellular matrix(dECM)derived from peripheral nerves(decellularized nerve matrix,DNM)has drawn increasing attention in the feld of regenerative medicine,due to its outstanding capabilities in facilitating neurite outgrowth and remyelination.To induce and maintain sufcient topological guidance,electrospinning was conducted for fabrication of axially aligned nanofbers consisting of DNM and poly(ε-caprolactone)(PCL).Core–shell structured fbers were prepared by coaxial electrospinning using DNM as the shell and PCL as the core.Compared to the aligned electrospun fbers using preblended DNM/PCL,the core–shell structured fbers exhibited lower tensile strength,faster degradation,but considerable toughness for nerve guidance conduit preparation and relatively intact fbrous structure after long-term degradation.More importantly,the full DNM surface coverage of the aligned core–shell fbers efectively promoted axonal extension and Schwann cells migration.The DNM contents further triggered neurite bundling and myelin formation toward nerve fber maturation and functionalization.Herein,we not only pursue a multi-functional scafold design for nerve regeneration,a detailed comparison between core–shell structured and preblended electrospinning of DNM/PCL composites was also provided as an applicable paradigm for advanced tissue-engineered strategies using dECM-based biomaterials. | Rongli Deng Ziling Luo Zilong Rao Zudong Lin Shihao Chen Jing Zhou Qingtang Zhu Xiaolin Liu Ying Bai Daping Quan | 2022 | Advanced Fiber Materials2022，4，3： | 0 |
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