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| 1 | Study of the mechanisms of acupuncture and moxibustion treatmentfor ulcerative colitis ratsinview of the gene expression of cytokines显示文摘AIM To observe the effect of acupuncture and moxibustion on the expression of IL 1β and IL 6 mRNA in ulcerative colitis rats. METHODS The SD rat ulcerative colitis model was created by immunological method associated with local stimulation. Colonic mucosa was prepared from human fresh surgical colonic specimens, homogenized by adding appropriate amount of normal saline and centrifuged at 3000*!r/*!min . The supernatant was collected for measurement of protein conentration and then mixed with Freund adjuvant. This antigen fluid was first injected into the plantae of the model group rats, and then into their plantae, dorsa, inguina and abdominal cavities (no Freund adjuvant for the last injection) again on the 10th, 17th, 24th and 31st day. When a certain titer of serum anti colonic antibody was reached, 2% formalin and antigen fluid (no Freund adjuvant) were administered separately by enema. The ulcerative colitis rat model was thus set up. The animals were randomly divided into four groups: model control group (MC, n =8), electro acupuncture group (EA, n =8), herbs partition moxibustion group (HPM 8), normal control group (NC, n =8). HPM: Moxa cones made of refined mugwort floss were placed on the medicinal pad (medicinal pad dispensing: Radix Aconiti praeparata, cortex Cinnamomi, etc ) for Qihai (RN 6) and Tianshu (ST 25, bilateral) and ignited. Two moxa cones were used for each acupoint once a day and 14 times in all. EA: Tianshu (bilateral) and Qihai were stimulated by the intermittent pulse with 2Hz frequency, 4mA intensity for 20 minutes once a day and 14 times in all. After treatment, rats of all four groups were killed simultaneously. The spleen was separated and the distal colon was dissected. Total tissue RNA was isolated by the guanidinium thiocyanate phenol chloroform extraction method. RT PCR technique was used to study the expression of IL 1β and IL 6 mRNA. RESULTS IL 1β and IL 6 mRNAs were not detected in the spleen and colonic mucosa of the NC rats, whereas they were significantly expressed in that of the MC rats. IL 1β and IL 6 mRNAs were markedly lower in the EA and HPM rats than that in MC rats. There was no significant difference between the levels of IL 1β and IL 6 mRNAs in the EA and HPM rats. The expressions of IL 1β and IL 6 mRNAs were nearly the same in the spleen and colon of all groups. CONCLUSION Acupuncture and moxibustion greatly inhibited the expression of IL 1β and IL 6 mRNA in the experimental ulcerative colitis rats. | Wu HG Zhou LB Pan YY Huang C Chen HP Shi Z Hua XG | 1999 | World Journal of Gastroenterology1999，5，6： | 45 |
| 2 | Economic burden of Parkinson's disease in a developing country: A retrospective cost analysis in Shanghai, China显示文摘 | Wang G Cheng Q Zheng R Tan YY Sun XK Zhou HY Ye XL Wang Y Wang Z Sun BM Chen SD | 2006 | 中国生物学文摘2006，20，8： | 10 |
| 3 | Synthesis and Characterization of Nanocrystalline Ni-Ti and Ni-Cr Powders by Mechanical Alloying显示文摘Nanocrystalline powders in the Ni-Ti and Ni-Cr systems were prepared by mechanical alloying (MA) of elemental crystalline powders in an inert atmosphere. The microstructure of the mechanically alloyed powders were characterized by XRD and TEM. The ball-milling process results in a drastic decrease of the crystallite size to the nanometer scale. X-ray diffraction analysis reveals that in the Ni-Cr system, no diffraction peaks from NiCr compound were observed even after 20 h of ball milling; while the lattice parameter of Ni increased with the milling time. In the Ni-Ti system, amorphous alloy was formed. Crystalline intermetallic compounds were obtained by post heat treatment of the amorphous alloy.The crystallization temperature of the amorphous NiTi alloy was obtained be DSC measurement. | Chen, SQ Zhou, YC Li, YY He, SH | 1997 | Journal of Materials Science & Technology1997，13，2： | 2 |
| 4 | A Model for Liquid-Diffusion Catalytically Grown Fibrous Carbon Material显示文摘A mechanism for the catalytically growth of vapor grown fibrous carbon (VGFC) preparing from the floating catalyst method has been proposed, in which liquid diffusion-determined diffusionof carbon atoms through catalyst particles is described mathematically, and the physical andchemical properties of the catalyst particIes during the growth process are taken into account.From the model the growth rate and grown length of VGFC are calculated theoretically whichcoincides with the experimental datal and the necessity of reducing gas such as hydrogen inpreparing VGFC is explained as to reduce Fe3C, which acts as intermediate catalyst shown bythe model. Fe3C formed on the surface of γ-Fe will stop the growth of carbon fiber if they cannot be reduced at once. Additionally, the growth temperature and diameter of VGFC are alsodiscussed in the paper. | Zhang, WG Cheng, HM Su, G Fan, YY Li, F Shen, ZH Zhou, BL | 1999 | Journal of Materials Science & Technology1999，15，1： | 2 |
| 5 | Patterns of lateral pelvic lymph node metastases and mierometastases for patients with lower rectal cancer 显示文摘 | Wang C Zhou ZG Yu YY | 2007 | Eur J Surg Oncol2007，33，4： | 1 |
| 6 | Annealing hardening in detwinning deformation of Mg-3AHZn alloy显示文摘 | YC Xin XJ Zhou HW Chen JF Nie H Zhang YY Zhang Qg Liu | 2014 | Materials Science and Engineering:A2014，594，： | 1 |
| 7 | Ginsenoside-Bd from panax notoginseng blocks Ca2+ influx through receptor-and store-operated Ca^2+ channels in vascular smooth muscle cells显示文摘 | Guan YY Zhou JG ZHANG Z | 2006 | gut J Pharmacol2006，548，： | 1 |
| 8 | AML1-ETO and C-KIT mutation/overexpression in t ( 8 ; 21 ) leukemia: implication in stepwise leukemogenesis and response to Gleevec 显示文摘 | Wang YY Zhou GB Yin T | 2005 | Proe Natl Acad SciU S A2005，102，4： | 1 |
| 9 | Molecular mechanism of haman essential Hypertension: a mutation in the proximal promoter of the angiotensinogen gene from hyperrtensive patients increases its transcription in human hepatoma cells 显示文摘 | Zhou J Kumar A | 1996 | Circulation1996，94，： | 1 |
| 10 | Antioxidant properties of polymeric proanthocyanidins from fruit stones and pericarps of Litchi chinensis Soma显示文摘 | Zhou HC Lin YM Li YY | 2011 | Food Res Int2011，44，2： | 1 |
| 11 | The technique for measurement path becontrolled based on surface reverse and ultrasonic easurement显示文摘 | l Wang YY Zhou XJ Cheng YD | 2002 | Proceedings of The 4th World Congress on Intelligent Control and Automation2002，，14： | 1 |
| 12 | Laparoscopic Versus Open Incisional and Ventral Hernia Repair: A Systematic Review and Meta-analysis 显示文摘 | Zhang YY Zhou HY Chai YS | 2014 | World J Surg2014，38，9： | 1 |
| 13 | AML1 -ETO and C - K/T mutation/overexpression in t ( 8 ; 21 ) leukemia: Implication in stepwise leukemogenesis and response to Gleevec显示文摘 | Wang YY Zhou GB Yin T | 2005 | Proc Nail Acad Sci USA2005，102，4： | 1 |
| 14 | Helicobacter pylori associated with a high prevalence ofduodenal ulcer disease and a low prevalence of gastric cancer in a developing nation显示文摘 | Hu PJ Li YY Zhou MH | 1995 | Gut1995，36，： | 1 |
| 15 | Performance of HbA ( 1 c) for de- tecting newly diagnosed diabetes and pre - diabetes in Chinese commu- nities living in Beijing 显示文摘 | Zhou XH Ji LN Luo YY | 2009 | Diabet Med2009，26，12： | 1 |
| 16 | Interleukin-17A expression in patients with chronic thinosinusitis and its relationship with clinical features显示文摘 | Hu XD Bao YY Zhou SH | 2013 | J Int Med Res2013，41，3： | 1 |
| 17 | The Schistosomajaponicum ge- nome reveals features of host-parasite interplay 显示文摘 | Zhou Y Zheng H Chen YY | 2009 | Nature2009，460，7253： | 1 |
| 18 | Correlation between stinging, TEWL and capacitance 显示文摘 | Wu YY Wang XM Zhou YT | 2003 | Skin Res Technol2003，9，： | 1 |
| 19 | Expression and significance of beta- catenin,Glut-1 and PTEN in proliferative endometrium,endometrial intraepithelial neoplasia and endometrioid adenocarcinoma 显示文摘 | Xiong Y Xiong YY Zhou YF | 2010 | Eur J Gynaecol Oncol2010，31，2： | 1 |
| 20 | The Schistosoma japonicum genome reveals features of host-parasite interplay显示文摘 | Zhou Y Zheng HJ Chen YY | 2009 | Nature2009，460，7253： | 1 |
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