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| 1 | Disinfection byproduct precursor removal by enhanced coagulation and their distribution in chemical fractions显示文摘Raw water from the Songhua River was treated by four types of coagulants, ferric chloride(FeCl3), aluminum sulfate(Al2(SO4)3),polyaluminum chloride(PACl) and composite polyaluminum(HPAC), in order to remove dissolved organic matter(DOM). Considering the disinfection byproduct(DBP) precursor treatability, DOM was divided into five chemical fractions based on resin adsorption.Trihalomethane formation potential(THMFP) and haloacetic acid formation potential(HAAFP) were measured for each fraction. The results showed that hydrophobic acids(HoA), hydrophilic matter(HiM) and hydrophobic neutral(HoN) were the dominant fractions.Although both HoN and HoA were the main THM precursors, the contribution for THMFP changed after coagulation. Additionally,HoA and HiM were the main HAA precursors, while the contribution of HoN to HAAFP significantly increased after coagulation.HoM was more easily removed than HiM, no matter which coagulant was used, especially under enhanced coagulation conditions.DOC removal was highest for enhanced coagulation using FeCl3 while DBPFP was lowest using PACl. This could indicate that not all DOC fractions contained the precursors of DBPs. Reduction of THMFP and HAAFP by PACl under enhanced coagulation could reach51% and 59% respectively. | Yanmei Zhao Feng Xiao Dongsheng Wang Mingquan Yan Zhe Bi | 2013 | Journal of Environmental Sciences2013，25，11： | 7 |
| 2 | Multivariate predictive model for asymptomatic spontaneous bacterial peritonitis in patients with liver cirrhosis显示文摘BACKGROUNDSpontaneous bacterial peritonitis (SBP) is a detrimental infection of the asciticfluid in liver cirrhosis patients, with high mortality and morbidity. Earlydiagnosis and timely antibiotic administration have successfully decreased themortality rate to 20%-25%. However, many patients cannot be diagnosed in theearly stages due to the absence of classical SBP symptoms. Early diagnosis ofasymptomatic SBP remains a great challenge in the clinic.AIMTo establish a multivariate predictive model for early diagnosis of asymptomaticSBP using positive microbial cultures from liver cirrhosis patients with ascites.METHODSA total of 98 asymptomatic SBP patients and 98 ascites liver cirrhosis patients withnegative microbial cultures were included in the case and control groups,respectively. Multiple linear stepwise regression analysis was performed toidentify potential indicators for asymptomatic SBP diagnosis. The diagnosticperformance of the model was estimated using the receiver operatingcharacteristic curve.RESULTSPatients in the case group were more likely to have advanced disease stages,cirrhosis related-complications, worsened hematology and ascites, and higher mortality. Based on multivariate analysis, the predictive model was as follows: y (P) = 0.018 + 0.312 × MELD (model of end-stage liver disease) + 0.263 × PMN(ascites polymorphonuclear) + 0.184 × N (blood neutrophil percentage) + 0.233 ×HCC (hepatocellular carcinoma) + 0.189 × renal dysfunction. The area under thecurve value of the established model was 0.872, revealing its high diagnosticpotential. The diagnostic sensitivity was 73.5% (72/98), the specificity was 86.7%(85/98), and the diagnostic efficacy was 80.1%.CONCLUSIONOur predictive model is based on the MELD score, polymorphonuclear cells,blood N, hepatocellular carcinoma, and renal dysfunction. This model mayimprove the early diagnosis of asymptomatic SBP. | Bo Tu Yue-Ning Zhang Jing-Feng Bi Zhe Xu Peng Zhao Lei Shi Xin Zhang Guang Yang En-Qiang Qin | 2020 | World Journal of Gastroenterology2020，26，29： | 5 |
| 3 | Elective neck dissection or "watchful waiting": optimal management strategy for early stage NO tongue carcinoma using decision analysis techniques显示文摘背景尽管舌头癌症是头和颈的普通疾病,在选任的颈解剖并且“警惕等待”之间的颈治疗的选择与早舞台为病人仍然保持争论没有口头的舌头 carcinoma.Methods 根据头和颈癌症的当前的状态,一个决定分析模型被创造为早舌头 cancer.Expected 价值( EV )比较二治疗策略根据遇见了定义 criteria.Sensitivity | SONG Tao BI Nan GUI Lai PENG Zhe | 2008 | Chinese Medical Journal2008，，17： | 5 |
| 4 | (±)-Zanthonitidine A,a Pair of Enantiomeric Furoquinoline Alkaloids from Zanthoxylum nitidum with Antibacterial Activity显示文摘A pair of new enantiomeric furoquinoline alkaloids,(±)-zanthonitidine A(1),together with nine known ones(2-10)were isolated from the radix of Zanthoxylum nitidum.Their chemical structures were elucidated based on the extensive spectroscopic analysis.The racemic mixture of 1 was separated by chiral column chromatography,and the absolute configurations of (+)-1 and(-)-1 were determined by the comparison of experimental and calculated electronic circular dichroism spectra.Antibacterial activities of compounds 1-9 were evaluated,and compounds(+)-1,(-)-1,3,7 and 8 showed antibacterial activities against Bacillus subtilis,Enterococcus faecalis or Staphylococcus aureus. | Li-Na Zhao Xi-Xi Guo Shuai Liu Li Feng Qi-Rui Bi Zhe Wang Ning-Hua Tan | 2018 | Natural Products and Bioprospecting2018，8，5： | 3 |
| 5 | microRNA-218 promotes gemcitabine sensitivity in human pancreatic cancer cells by regulating HMGB1 expression显示文摘Objective: The purpose of this study was to examine the effect of gemcitabine(GEM) on micro RNA-218(mi R-218) expression in human pancreatic cancer cells.Methods: Quantitative reverse transcription polymerase chain reaction(q RT-PCR) was performed to examine the differences in mi R-218 expression between the GEM-sensitive Bx PC-3 pancreatic cancer cells and GEM-resistant PANC-1 cells. The effect of GEM on the expression of mi R-218 in PANC-1 cells was also investigated. PANC-1 cells were transfected either with HMGB1 si RNA to knock down the expression of HMGB1 or with the recombinant HMGB1 expression vector(pc DNA3.1-HMGB1) to overexpress HMGB1. The effect of ectopic expression of HMGB1 on the apoptosis of mi R-218-transfected and GEMtreated PANC-1 cells was examined by flow cytometric analysis.Results: The mi R-218 expression level was lower in GEM-resistant PANC-1 cells compared to GEMsensitive Bx PC-3 cells(P<0.05). The percentage of apoptotic PANC-1 cells was significantly increased in the mi R-218 mimic + GEM group compared to the mimic ctrl + GEM group and the normal control group(P<0.01). The HMGB1 expression level was markedly decreased in PANC-1 cells transfected with HMGB1 si RNA but was significantly increased in PANC-1 cells transfected with the recombinant HMGB1 expression vector, pc DNA3.1-HMGB1(P<0.01). The proportion of apoptotic PANC-1 cells was significantly lower in the mi R-218 mimic + GEM + pc DNA3.1-HMGB1 group compared to the mi R-218 mimic + GEM + HMGB1 si RNA group(P<0.01).Conclusions: The expression level of mi R-218 was downregulated in the GEM-resistant cell line. mi R-218 promoted the sensitivity of PANC-1 cells to GEM, which was achieved mainly through regulating the expression of HMGB1 in PANC-1 cells. | Zhe Liu Ruixia Du Jin Long Kejian Guo Chunlin Ge Shulong Bi Yuanhong Xu | 2015 | Chinese Journal of Cancer Research2015，27，3： | 2 |
| 6 | Anti-diabetic effects of linarin from Chrysanthemi Indici Flos via AMPK activation显示文摘Objective:The purpose of this study is to investigate the anti-diabetic effects of linarin,a flavonoid extracted from Chrysanthemi Indici Flos(CIF),and its potential mechanisms.Methods:The effects of linarin on cell viability and glucose consumption in Hep G2 cells were measured.Meanwhile,monosodium glutamate(MSG) mouse model was constructed to monitor the changes of insulin tolerance,glucose tolerance,triglyceride and cholesterol.The protein expression levels of pAMPK,p-ACC,PEPCK and p-GS were detected by Western blot.Results:Linarin could increase the relative glucose consumption of Hep G2 cells,improve insulin tolerance and glucose tolerance,and decrease the levels of triglyceride and cholesterol of MSG mice.Simultaneously,the expression levels of p-AMPK and p-ACC in Hep G2 cells and the liver tissue of MSG mice were increased,while the expression levels of PEPCK and p-GS were decreased after treatment with linarin.Conclusion:Insulin resistance could be ameliorated by linarin in type 2 diabetes,and its mechanism may be related to AMPK signaling pathway. | Zhenji Wang Zhe Bai Jinghua Yan Tengteng Liu Yingmei Li Jiahui Xu Xiaoqian Meng Yuefeng Bi | 2022 | Chinese Herbal Medicines2022，14，1： | 2 |
| 7 | ANALYSIS OF FREEMIUM BUSINESS MODEL CONSIDERING NETWORK EXTERNALITIES AND CONSUMER UNCERTAINTY显示文摘公司逐渐地在联机软件市场使用的一个新兴的企业模型将两个都为为顾客的一种服务或一个产品提供一个免费基本版本和一个付的高级版本。如此的一个背景经常被称为 freemium 模型。免费版本的存在能关于商业软件的评估减少顾客无常并且使用网络效果改进公司利润。然而, freemium 模型可以也让 cannibalization 完成哪个罐头伤害了利润。因此,公司需要为免费版本和最佳的价格决定最佳的内容让高级版本最大化它的利润。在这份报纸,首先,我们获得 freemium 模型和他们的性质的最佳的决定。第二,我们把 freemium 模型与产品满意的所有需要以利润,顾客福利,和社会福利被收的传统的 charge-for-everything 模型作比较。结果证明当顾客显著地低估软件的值,软件的真值足够高时, freemium 模型能产生更高的利润,更高级的顾客福利,和更高社会的福利。否则, freemium 模型不能交付需要的结果。 | Wuhua Chen Zhongsheng Hua Zhe George Zhang Wenjie Bi | 2018 | Journal of Systems Science and Systems Engineering2018，27，1： | 2 |
| 8 | An Aptamer-based Colorimetric Sensor for Streptomycin and Its Application in Food Inspection显示文摘 | LIU Zhongcheng ZHANG Yanfen XIE Yao SUN Ying BI Kewei CUI Zhe ZHAO Lijian FAN Wufang | 2017 | Chemical Research in Chinese Universities2017，33，5： | 2 |
| 9 | Unusual polymeri- zation activities of bulky aluminum alkyl complexes 显示文摘 | Bi Xiangdong Wang Dekun Wu Zhe | 2001 | Journal of Molecular Catalysis : A : Chemical2001，179，： | 1 |
| 10 | Formation of AI from aqueous polyaluminum chloride under high tem- perature : Role of Alt3 aggregates 显示文摘 | Ye Changqing Bi Zhe Wang Dongsheng | 2013 | Colloids and Surfaces A : Physicochem Eng Aspects2013，436，123： | 1 |
| 11 | Simultaneous decolorization of azo dye and bioelectricity generation using a microfiltration membrane air-cathode single-chamber microbial fuel cell 显示文摘 | Sun Jian Hu Yongyou Bi Zhe | 2009 | Biore- source Technology2009，100，13： | 1 |
| 12 | Further treatment of decolorization liquid of azo dye coupled with increased power productionusing microbial fuel cell equipped with an aerobic biocathode显示文摘 | JJAN Sun ZHE Bi BIN Hou | 2011 | Water Research2011，45，1： | 1 |
| 13 | The Solar Upper Transition Region Imager(SUTRI)Onboard the SATech-01 Satellite显示文摘The Solar Upper Transition Region Imager(SUTRI)onboard the Space Advanced Technology demonstration satellite(SATech-01),which was launched to a Sun-synchronous orbit at a height of~500 km in 2022 July,aims to test the on-orbit performance of our newly developed Sc/Si multi-layer reflecting mirror and the 2k×2k EUV CMOS imaging camera and to take full-disk solar images at the Ne VII 46.5 nm spectral line with a filter width of~3 nm.SUTRI employs a Ritchey-Chrétien optical system with an aperture of 18 cm.The on-orbit observations show that SUTRI images have a field of view of~416×416 and a moderate spatial resolution of~8″without an image stabilization system.The normal cadence of SUTRI images is 30 s and the solar observation time is about16 hr each day because the earth eclipse time accounts for about 1/3 of SATech-01's orbit period.Approximately15 GB data is acquired each day and made available online after processing.SUTRI images are valuable as the Ne VII 46.5 nm line is formed at a temperature regime of~0.5 MK in the solar atmosphere,which has rarely been sampled by existing solar imagers.SUTRI observations will establish connections between structures in the lower solar atmosphere and corona,and advance our understanding of various types of solar activity such as flares,filament eruptions,coronal jets and coronal mass ejections. | Xianyong Bai Hui Tian Yuanyong Deng Zhanshan Wang Jianfeng Yang Xiaofeng Zhang Yonghe Zhang Runze Qi Nange Wang Yang Gao Jun Yu Chunling He Zhengxiang Shen Lun Shen Song Guo Zhenyong Hou Kaifan Ji Xingzi Bi Wei Duan Xiao Yang Jiaben Lin Ziyao Hu Qian Song Zihao Yang Yajie Chen Weidong Qiao Wei Ge Fu Li Lei Jin Jiawei He Xiaobo Chen Xiaocheng Zhu Junwang He Qi Shi Liu Liu Jinsong Li Dongxiao Xu Rui Liu Taijie Li Zhenggong Feng Yamin Wang Chengcheng Fan Shuo Liu Sifan Guo Zheng Sun Yuchuan Wu Haiyu Li Qi Yang Yuyang Ye Weichen Gu Jiali Wu Zhe Zhang Yue Yu Zeyi Ye Pengfeng Sheng Yifan Wang Wenbin Li Qiushi Huang Zhong Zhang | 2023 | Research in Astronomy and Astrophysics2023，23，6： | 1 |
| 14 | Simultaneous decolori-zation of azo dye and bioelectricity generation using a microfil-tration membrane air-cathode single-chamber microbial fuelcell显示文摘 | SUN Jian HU Yongyou BI Zhe | 2009 | Bioresource Technology2009，100，13： | 1 |
| 15 | Quantitative proteomic analysis of host responses triggered by Mycobacterium tuberculosis infection in human macrophage cells显示文摘 | Hua Li Sha Wei Yuan Fang Min Li Xia Li Zhe Li Jibin Zhang Guofeng Zhu Chuanyou Li Lijun Bi Guimin Zhang Dianbing Wang Xian-En Zhang | 2017 | Acta Biochimica et Biophysica Sinica2017，49，9： | 1 |
| 16 | Surface-adsorbed ions on TiO2 nanosheets for selective photocatalytic CO2 reduction显示文摘 | Xiaogang Li Wentuan Bi Zhe Wang Wenguang Zhu Wangsheng Chu Changzheng Wu Yi Xie | 2018 | Nano Research2018，11，6： | 1 |
| 17 | Antioxidation and active constituents analysis of flower residue of Rosa damascena显示文摘Objective:To make full usage of resource and turn waste into treasure,the chemical constituents and bioactivity were firstly investigated on Damask rose(Rosa damascena)flower residue(DRFR).Methods:DPPH and ABTS experiments were applied to assess the antioxidant activity of DRFR.Then,column chromatography was used to purify compounds from an antioxidation extract(DRFR-A),and the chemical structure was identified using NMR.The total phenolic acid content was measured by FolinCiocalteu colorimetric method,and the content of gallic acid of the indicator ingredient was detected by HPLC.Results:DRFR-A was found to show a high activity both on DPPH(IC5o:2.760μg/mL)and ABTS(ICso:2.258μg/mL)compared to positive control Vc,Ten compounds were isolated and identified as quercetin(1),kaempferol(2),gallic acid(3),protocatechuic acid(4),pyrogallic acid(5),2-phenylethyl 3,4,5-trihydroxybenzoate(6),methyl gallate(7),p-hydroxybenzoic acid(8),p-hydroxyphenethyl alcohol(9)and astragalin(10)from DRFR-A.Among them,pyrogallic acid,2-phenylethyl-3,4,5-trihydroxybenzoate,p-hydroxybenzoic acid and p-hydroxyphenethyl alcohol are obtained from the plant for the first time.The content of total phenolic acids and gallic acid,main ingredient in DRFR-A was determined as 63.73%and 24.67%,respectively.Conclusion:This study provides a reliable data and lays the foundation for the development and utilization of rose residue,and hence for the full utilization of rose resources. | Wen-ya Liu Lin-yu Chen Ying-ying Huang Ling Fu Le-yuan Song Yun-yu Wang Zhe Bai Fang-feng Meng Yue-feng Bi | 2020 | Chinese Herbal Medicines2020，12，3： | 1 |
| 18 | Improved performance of air-cathode single-chamber microbial fuel cell for wastewater reatment using microfihration membranes and multiple sludge inoculation 显示文摘 | Sun Jian Hu Yongyou Bi Zhe | 2008 | Journal of Power Sources2008，187，2： | 1 |
| 19 | Effect of photoperiod on development and reproduction of Megacopta cribraria(Hemiptera:Plataspidae)显示文摘Megacopta cribraria (Hemiptera: Plataspidae) continually outbreaks due to suitable photoperiod in recent years. Effect of photoperiod on growth, development and reproduction of M. cribraria were assessed in this study. Results indicated that developmental duration, nutrient accumulation efficiency, and adult fecundity of M. cribraria were significantly different under 6 photoperiodical conditions. Developmental duration of nymph stage gradually tended to be shorter as day time increase. Body weights of 5th instar nymphs for 16 h and 4 h day time photoperiods were 5.2 mg and 4.6 mg, respectively. Moreover, longevity of adults tended to be longer as day time increase. However, for the short day photoperiod (4 L:20 D and 8 L:16 D), population showed no reproductive behaviors. Index of population trend increased with photoperiod extension and adults showed stronger reproductive capacity and longer longevity. This research identified the favorable photoperiodical conditions before outbreak. It may provided reference for ecological adaptability of M. cribraria, and contribute to the scientific basis for forecasting and controlling of M. cribraria. | Zhe Xu Juan Cui Rui Bi Wei Xu Shusen Shi Yu Gao | 2019 | Oil Crop Science2019，4，2： | 1 |
| 20 | Antioxidation and active constituents analysis of flower residue of Rosa Damascena Mill显示文摘OBJECTIVE To make full of resource,the bioactivity and active constituent analysis were firstly system⁃atically investigated on damask rose flower residue(DRFR).METHODS DPPH and ABTS experiments were applied to assess the antioxidant activity of DRFR.Then,column chromatography was used to purify compounds from DRFR-A,and the chemical structure was identified using nuclear magnetic resonance(NMR).The total phenolic acid content was measured by folin-ciocalteu colorimetric method and the content of gallic acid the indicator ingredient,was detected by high performance liquid chromatography(HPLC).RESULTS By DPPH and ABTS experiments,an antioxidation extract(DRFR-A)was found and displayed a high activity both on DPPH(IC50:2.760 mg·L^-1)and ABTS(IC50:2.258 mg·L^-1)compared to positive control VC.Ten compounds were isolated and identified from DRFR-A,and the most are phenolic acids.Among them,pyrogallic acid,2-phenylethyl-3,4,5-trihydroxybenzoate,p-hydroxybenzoic acid and p-hydroxy⁃phenethyl alcohol were obtained from the plant for the first time.The content of total phenolic acids and main ingredient,gallic acid,in DRFR-A was determined as 63.73%and 5.12%,respectively.CONCLUSION This study provides reliable science data and lays the foundation for the development and utilization of rose residue,and hence for the full utilization of rose resources. | LIU Wen-ya CHEN Lin-yu HUANG Ying-ying FU Ling SONG Le-yuan WANG Yun-yu BAI Zhe MENG Fang-feng BI Yue-feng | 2019 | 中国药理学与毒理学杂志2019，33，9： | 1 |
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