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| 1 | Repress,on of MYBL2 by Both microRNA858a and HY5 Leads to the Activation of Anthocyanin Biosynthetic Pathway in Arabidopsis显示文摘 | Yulong Wang Yiqing Wang Zhaoqing Song Huiyong Zhang | 2016 | Molecular Plant2016，9，10： | 27 |
| 2 | Effects of the dispatch modes of the Three Gorges Reservoir on the water regimes in the Dongting Lake area in typical years显示文摘在典型的年里基于地调查原型水文学数据,效果在在东廷·莱克区域的水政体上的三座峡水库的不同派遣模式的跑的时期期间是比较地分析了。结果如下被显示出。(1 ) 影响时期从 5 月 25 日到 6 月 10 日,从 7 月 1 日到 8 月 31 日,从 9 月 15 日到 10 月 31 日并且从 12 月到下一 4 月,在旱季的水补充派遣的影响不在之中是很敏感的。(2 ) 在在预先解除下面的时期期间派遣,流量体积稍微在平常的年里象平均的水水平和高水位线水平上升一样增加。当时在湿、干燥的年里,流量体积的平均增加是 40. | OU Chaomin LI Jingbao ZHANG Zhaoqing LI Xichun YU Guo LIAO Xiaohong | 2012 | Journal of Geographical Sciences2012，22，4： | 12 |
| 3 | Early prediction of pathological outcomes to neoadjuvant chemotherapy in breast cancer patients using automated breast ultrasound显示文摘Objective: Early assessment of response to neoadjuvant chemotherapy(NAC) for breast cancer allows therapy to be individualized.The optimal assessment method has not been established.We investigated the accuracy of automated breast ultrasound(ABUS) to predict pathological outcomes after NAC.Methods: A total of 290 breast cancer patients were eligible for this study.Tumor response after 2 cycles of chemotherapy was assessed using the product change of two largest perpendicular diameters(PC) or the longest diameter change(LDC).PC and LDC were analyzed on the axial and the coronal planes respectively.Receiver operating characteristic(ROC) curves were used to evaluate overall performance of the prediction methods.Youden's indexes were calculated to select the optimal cut-off value for each method.Sensitivity, specificity,positive and negative predictive values(PPV and NPV) and the area under the ROC curve(AUC) were calculated accordingly.Results: yp T0/is was achieved in 42 patients(14.5%) while yp T0 was achieved in 30 patients(10.3%) after NAC.All four prediction methods(PC on axial planes, LDC on axial planes, PC on coronal planes and LDC on coronal planes) displayed high AUCs(all>0.82), with the highest of 0.89 [95% confidence interval(95% CI), 0.83–0.95]when mid-treatment ABUS was used to predict final pathological complete remission(p CR).High sensitivities(85.7%–88.1%) were observed across all four prediction methods while high specificities(81.5%–85.1%) were observed in two methods used PC.The optimal cut-off values defined by our data replicate the WHO and the RECIST criteria.Lower AUCs were observed when mid-treatment ABUS was used to predict poor pathological outcomes.Conclusions: ABUS is a useful tool in early evaluation of p CR after NAC while less reliable when predicting poor pathological outcomes. | Xinguang Wang Ling Huo Yingjian He Zhaoqing Fan Tianfeng Wang Yuntao Xie Jinfeng Li Tao Ouyang | 2016 | Chinese Journal of Cancer Research2016，28，5： | 11 |
| 4 | 大学生饮酒模式调查分析显示文摘目的分析影响大学生饮酒模式的因素,针对饮酒教育及酒精政策提出建议。方法采用整群抽样方法,选择来自北京和郑州的530名大学生完成有效问卷调查。采用Epidata录入数据,SAS 12.0和R 2.7.2进行数据描述和分析。结果 74.5%的大学生在过去1年内饮过酒,啤酒是饮酒者的主要选择(85.9%),餐馆和家里是饮酒比较频繁的场所,饮用酒多来自同学/朋友及家庭成员提供,25.3%饮酒者并无特别原因饮酒,各有约1/5的饮酒者是出于社交目的或喜欢饮酒的感觉。认为'饮酒有助于社交'或'饮酒促进交流'者、父母及同学/朋友饮酒者、来自农村地区或小城镇者及吸烟者更容易发生饮酒行为(均P<0.05),男生大学生、规律饮酒者更容易遭遇强迫劝酒场面、更易发生醉酒(均P<0.05)。超过一半饮酒者出现酒后脸红、肌肉软弱无力等生理反应,饮酒对被调查大学生产生的社会心理影响依次是记忆丧失(23.9%)、宿醉(14.6%)、做了后悔的事(低于10%)等。结论目前大学生仍保持着一种低风险饮酒模式。大学生饮酒教育应提供关于饮酒利弊的科学信息,使其对饮酒保持一种现实的期望。应制定针对性酒精政策和教育鼓励和支持低风险且满足社交功能的饮酒模式,控制高风险饮酒模式。 | Newman IM Huang Zhaoqing Shell DF 钱玲 | 2014 | 中国社会医学杂志2014，31，2： | 10 |
| 5 | pH-Sensitive nanoscale materials as robust drug delivery systems for cancer therapy显示文摘Cancer is one of the diseases that have the highest mortality,which threatens the human health.Chemotherapy functions as the most widely used strategy in clinic to treat cancer,still exists urgent problems,like lacking selectivity and causing severe side effects.According to detailed researches on the metabolism,functions and histology of cancer tissues,many different features of cancer are uncovered,like lower pH in microenvironment,abnormal redox level in intracellular compartments and elevated expression level of several enzymes and receptors.Recently,the development of smart nanoparticles that response to tumor specific microenvironment has lighted up hope for selective cancer therapy.Herein,this review mainly focuses on pH-sensitive nano scale materials for anti-cancer drug delivery.We summarized the formation progress of acidic tumor microenvironment,the mechanism of pHresponsive drug delivery system and nanomaterials that responsive to acidic pH in tumor microenvironment. | Zhaoqing Shi Qianqian Li Lin Mei | 2020 | Chinese Chemical Letters2020，31，6： | 9 |
| 6 | Cancer-associated fibroblasts in breast cancer:Challenges and opportunities显示文摘The tumor microenvironment is proposed to contribute substantially to the progression of cancers,including breast cancer.Cancer-associated fibroblasts(CAFs)are the most abundant components of the tumor microenvironment.Studies have revealed that CAFs in breast cancer originate from several types of cells and promote breast cancer malignancy by secreting factors,generating exosomes,releasing nutrients,reshaping the extracellular matrix,and suppressing the function of immune cells.CAFs are also becoming therapeutic targets for breast cancer due to their specific distribution in tumors and their unique biomarkers.Agents interrupting the effect of CAFs on surrounding cells have been developed and applied in clinical trials.Here,we reviewed studies examining the heterogeneity of CAFs in breast cancer and expression patterns of CAF markers in different subtypes of breast cancer.We hope that summarizing CAFrelated studies from a historical perspective will help to accelerate the development of CAF-targeted therapeutic strategies for breast cancer. | Dengdi Hu Zhaoqing Li Bin Zheng Xixi Lin Yuehong Pan Peirong Gong Wenying Zhuo Yujie Hu Cong Chen Lini Chen Jichun Zhou Linbo Wang | 2022 | Cancer Communications2022，42，5： | 9 |
| 7 | FXYD6: a novel therapeutic target toward hepatocellular carcinoma显示文摘FXYD6, FXYD 领域包含离子运输管理者 6,被报导了影响 Na 的活动 < 啜 class= “ a-plus-plus ” >+/K+-ATPase 并且与心理疾病被联系。这里,我们证明 FXYD6 在 hepatocellular 癌(HCC ) 是起来调整的并且提高 HCC 房间的迁居和增长。FXYD6 的起来规定不仅断然随 Na 的增加相关 < 啜 class= “ a-plus-plus ” >+/K 有它发信号的下游的 Src 英皇家空军之阶级最低之兵的激活的 +-ATPase 而且坐标小径。更重要地,显著地由它的功能的抗体堵住 FXYD6 在老鼠禁止 xenografted HCC 肿瘤的生长潜力,显示 FXYD6 代表向 HCC 的一个潜在的治疗学的目标。总的来说,我们的结果在 HCC 前进建立 FXYD6 的一个关键角色并且建议指向 FXYD6 的治疗能向 HCC 病人有益于临床的治疗。 | Qian Gao Xiongfei Chen Hongxia Duan Zhaoqing Wang Jing Feng Dongling Yang Lina Song Ningxin Zhou Xiyun Yan | 2014 | Protein & Cell2014，5，7： | 7 |
| 8 | Quantitative Simulation on Soil Moisture Contents of Two Typical Vegetation Communities in Sanjiang Plain,China显示文摘Different types of vegetation occupy different geomorphology and water gradient environments in the San-jiang Plain,indicating that the soil moisture dynamics and water balance patterns of the different vegetation communi-ties might differ from each other.In this paper,a lowland system,perpendicular to the Nongjiang River in the Honghe National Nature Reserve(HNNR),was selected as the study area.The area was occupied by the non-wetland plant forest and the typical wetland plant meadow.The Microsoft Windows-based finite element analysis software package for simulating water,heat,and solute transport in variably saturated porous media(HYDRUS),which can quantita-tively simulate water,heat,and/or solute movement in variably-saturated porous media,was used to simulate soil moisture dynamics in the root zone(20-40 cm) of those two plant communities during the growing season in 2005.The simulation results for soil moisture were in a good agreement with measured data,with the coefficient of determi-nation(R2) of 0.44-0.69 and root mean square error(RMSE) ranging between 0.0291 cm3/cm3 and 0.0457 cm3/cm3,and index of agreement(d) being from 0.612 to 0.968.During the study period,the volumetric soil moisture content of meadow increased with the depth and its coefficient of variation decreased with the depth(from 20 cm to 40 cm),while under the forest the soil moisture content at different depths varied irregularly.The calculated result of water budget showed that the water budget deficit of the meadow was higher than that of the forest,suggesting that the meadow is more likely to suffer from water stress than the forest.The quantitative simulation by HYDRUS in this study did not take surface runoff and plant growth processes into account.Improved root water uptake and surface runoff models will be needed for higher accuracy in further researches. | LI Shanghua ZHOU Demin LUAN Zhaoqing PAN Yun JIAO Cuicui | 2011 | Chinese Geographical Science2011，21，6： | 7 |
| 9 | Application of Stable Isotope Tracing Technologies in Identification of Transformation among Waters in Sanjiang Plain,Northeast China显示文摘In order to investigate the transformation among the precipitation,groundwater,and surface water in the Sanjiang Plain,Northeast China,precipitation and groundwater samples which were collected at the meteorological station of the Sanjiang Mire Wetland Experimental Station,Chinese Academy of Sciences and the surface water which collected from the Wolulan River were used to identify the transformation of three types of water.The isotope composition of different kinds of water sources were analyzed via stable isotope(deuterium and oxygen-18) investigation of natural water.The results show a clear seasonal difference in the stable isotopes in precipitation.During the cold half-year,the mean stable isotope in precipitation in the Sanjiang Plain reaches its minimum with the minimum temperature.The δ18O and δD values are high in the rainy season.In the Wolulan River,the evaporation is the highest in August and September.The volume of evaporation and the replenishment to the river is mostly same.The groundwater is recharged more by the direct infiltration of precipitation than by the river flow.The results of this study indicate that the water bodies in the Sanjiang Plain have close hydrologic relationships,and that the transformation among each water system frequently occurs. | XU Yingying YAN Baixing LUAN Zhaoqing ZHU Hui WANG Lixia | 2013 | Chinese Geographical Science2013，23，4： | 6 |
| 10 | Selection of a DNA barcode for Nectriaceae from fungal whole-genomes显示文摘A DNA barcode is a short segment of sequence that is able to distinguish species. A barcode must ideally contain enough variation to distinguish every individual species and be easily obtained. Fungi of Nectriaceae are economically important and show high species diversity. To establish a standard DNA barcode for this group of fungi, the genomes of Neurospora crassa and 30 other filamentous fungi were compared. The expect value was treated as a criterion to recognize homologous sequences. Four candidate markers, Hsp90, AAC, CDC48, and EF3, were tested for their feasibility as barcodes in the identification of 34 well-established species belonging to 13 genera of Nectriaceae. Two hundred and fifteen sequences were analyzed. Intraand inter-specific variations and the success rate of PCR amplification and sequencing were considered as important criteria for estimation of the candidate markers. Ultimately, the partial EF3 gene met the requirements for a good DNA barcode: No overlap was found between the intra-and inter-specific pairwise distances. The smallest inter-specific distance of EF3 gene was 3.19%, while the largest intra-specific distance was 1.79%. In addition, there was a high success rate in PCR and sequencing for this gene (96.3%). CDC48 showed sufficiently high sequence variation among species, but the PCR and sequencing success rate was 84% using a single pair of primers. Although the Hsp90 and AAC genes had higher PCR and sequencing success rates (96.3% and 97.5%, respectively), overlapping occurred between the intraand inter-specific variations, which could lead to misidentification. Therefore, we propose the EF3 gene as a possible DNA barcode for the nectriaceous fungi. | ZENG ZhaoQing ZHAO Peng LUO Jing ZHUANG WenYing YU ZhiHe | 2012 | Science China(Life Sciences)2012，55，1： | 6 |
| 11 | Research on Advertising and Pricing in E-Supply Chain Under Different Dominant Modes显示文摘The E-supply chain is formed gradually along with the development of network, which is getting more attention among enterprises with unique advantages. Three E-supply chain operation modes are constructed in this paper, then the optimal pricing and advertising strategies under those modes are studied and compared, which are demonstrated with numerical examples. The results of comparison and analysis show that: Selling price, network platform service level, advertising investment and the profits of manufacturer, network platform and E-supply chain all increase with advertising effectiveness of stimulating demand growth. Under centralized decision-making mode, service level is highest, advertising investment is largest and the profit of E-supply chain is highest as well. When manufacturer leads decentralized decision-making mode, not only network service level, advertising investment and the profit of manufacturer can gain better results, but also profit of network platform can be higher while the advertisement effect of increasing demand is big enough. Additionally, it is confirmed that centralized decision-making is better than decentralized decision-making for system operation. Besides, decentralized decision-making mode led by manufacturer is superior to it led by network platform on the condition that advertisement effect is obvious. | Yuyan WANG Zhaoqing YU | 2018 | Journal of Systems Science and Information2018，9，1： | 5 |
| 12 | Rare-earth element geochemistry reveals the provenance of sediments on the southwestern margin of the Challenger Deep显示文摘The hadal zone represents one of the last great frontiers in modern marine science,and deciphering the provenance of sediment that is supplied to these trench settings remains a largely unanswered question.Here,we examine the mineralogical and geochemical composition of a sediment core(core CD-1)that was recovered from the southwestern margin of the Challenger Deep within the Mariana Trench.Major element abundances and rare-earth element patterns from these sediments require inputs from both terrigenous dust and locally sourced volcanic debris.We exploit a two-endmember mixing model to demonstrate that locally sourced volcanic material dominates the sediment supply to the Challenger Deep(averaging^72%).The remainder,however,is supplied by aeolian dust(averaging^28%),which is consistent with adjacent studies that utilized Sr-Nd isotopic data.Building on a growing database,we strengthen our understanding of Asian aeolian dust input into the northwestern Pacific,which ultimately improves our appreciation of sedimentation in,and around,the hadal zone. | JIANG Zuzhou SUN Zhilei LIU Zhaoqing CAO Hong GENG Wei XU Haixia WANG Lisheng WANG Libo | 2019 | Journal of Oceanology and Limnology2019，37，3： | 5 |
| 13 | B-box proteins:Pivotal players in light-mediated development in plants^FA显示文摘Light signals mediate a number of physio-logical and developmental processes in plants, such as flowering, photomorphogenesis, and pigment accu-mulation. Emerging evidence has revealed that a group of B-box proteins (BBXs) function as central players in these light-mediated developmental processes. B-box proteins are a class of zinc-coordinated transcription factors or regulators that not only directly mediate the transcription of target genes but also interact with various other factors to create a complex regulatory network involved in the precise control of plant growth and development. This review summarizes and highlights the recent findings concerning the critical regulatory functions of BBXs in photoperiodic flow-ering, light signal transduction and light-induced pigment accumulation and their molecular modes of action at the transcriptional and post-translational levels in plants. | Zhaoqing Song Yeting Bian Jiujie Liu Yuting Sun Dongqing Xu | 2020 | Journal of Integrative Plant Biology2020，62，9： | 5 |
| 14 | Single event upset rate modeling for ultra-deep submicron complementary metal-oxide-semiconductor devices显示文摘Based on the integral method of single event upset(SEU) rate and an improved charge collection model for ultra-deep submicron complementary metal-oxide-semiconductor(CMOS) devices, three methods of SEU rate calculation are verified and compared. The results show that the integral method and the figure of merit(FOM) methods are basically consistent at the ultra-deep submicron level. By proving the validity of the carrier collection model considering charge sharing, the applicability of two FOM methods is verified, and the trends of single-bit and multiple-bit upset rates for ultra-deep submicron CMOS are analyzed. | Liang HE Hua CHEN Peng SUN Xiaofei JIA Chongguang DAI Jing LIU Long SHAO Zhaoqing LIU | 2016 | Science China(Information Sciences)2016，59，4： | 5 |
| 15 | Spatial distribution patterns of wetland plants in relation to environmental gradient in the Honghe National Nature Reserve, Northeast China显示文摘在自然沼泽地植物和环境坡度的空间模式之间的确定的关联给沼泽地产地的更好的理解,它是为在自然沼泽地的保护和恢复上做的策略的基础。在这研究,沼泽地植物和沼泽地产地的环境坡度的空间模式在东北中国在 Honghe 国家自然保护区(HNNR ) 被估计, Ramsar 表上的国际重要性的一块沼泽地。沼泽地植物的生物物理的参数值被领域采样方法获得,并且在社区规模印射的沼泽地用遥感技术被完成。表面水系统,水文学 zoning 和湿索引的数字描述被空间分析方法在地理信息系统生产。一个生态的分类方法和二个聚类方法被用来确定在沼泽地植物和相应环境坡度的空间分发模式之间的关系。如此的量的分析也基于他们的产地的环境属性介绍沼泽地植物的不同类型的特定的差异。与从现代 geo 信息技术的支持,试验性的结果显示怎么沼泽地的四生态型空间地与增加湿从森林沼泽地,灌木沼泽地和草地种运输进沼泽地沼泽地索引和水桌子。并且他们也显示出怎么沼泽地空间分发模式被湿的一个环境坡度控制。研究工作是我们的结果介绍沼泽地和非沼泽地之间的准确基本差别的这的另一关键发现在核心学习区域以内 11 个沼泽地植物社区种。因此,这案例研究用先进数字分析方法为在沼泽地植物和他们的环境属性的空间模式之间的复杂关联的更好的理解给一件好样品。显示出怎么基于领域数据库与统计分析方法集成 geoinformatic 技术也是有用的。 | ZHOU Demin LUAN Zhaoqing GUO Xiaoyu LOU Yanjing | 2012 | Journal of Geographical Sciences2012，22，1： | 4 |
| 16 | Symphony of nanomaterials and immunotherapy based on the cancer-immunity cycle显示文摘The immune system is involved in the initiation and progression of cancer. Research on cancer and immunity has contributed to the development of several clinically successful immunotherapies. These immunotherapies often act on a single step of the cancer-immunity cycle. In recent years, the discovery of new nanomaterials has dramatically expanded the functions and potential applications of nanomaterials. In addition to acting as drug-delivery platforms, some nanomaterials can induce the immunogenic cell death(ICD) of cancer cells or regulate the profile and strength of the immune response as immunomodulators.Based on their versatility, nanomaterials may serve as an integrated platform for multiple drugs or therapeutic strategies, simultaneously targeting several steps of the cancer-immunity cycle to enhance the outcome of anticancer immune response. To illustrate the critical roles of nanomaterials in cancer immunotherapies based on cancer-immunity cycle, this review will comprehensively describe the crosstalk between the immune system and cancer, and the current applications of nanomaterials, including drug carriers, ICD inducers, and immunomodulators. Moreover, this review will provide a detailed discussion of the knowledge regarding developing combinational cancer immunotherapies based on the cancer-immunity cycle, hoping to maximize the efficacy of these treatments assisted by nanomaterials. | Qianqian Li Zhaoqing Shi Fan Zhang Weiwei Zeng Dunwan Zhu Lin Mei | 2022 | Acta Pharmaceutica Sinica B2022，12，1： | 4 |
| 17 | Te0.045S0.955PAN composite with high average discharge voltage for Li–S battery显示文摘As a sulfur-containing cathode material,sulfide polyacrylonitrile(SPAN)is expected to be used for longlife lithium-sulfur battery because there is no shuttle effect occurred in its charge process.However,its specific capacity and discharge potential need to be further improved to satisfy the urgent demands for high-performance batteries.In this paper,Te0.045S0.955PAN composite was synthesized by co-heating TexS1-x and PAN,and the superior electrochemical performance to that of SPAN was obtained because of doping Te with high conductivity.The as-prepared Te0.045S0.955PAN composite possessed the specific capacity of 675 mAh g^-1 after 100 cycles at the current density of 0.1 A g^-1 with high capacity retention of96.6%compared to the second cycle.Especially,during cycling,Te0.045S0.955PAN showed average discharge voltages of 1.88-1.91 V,which were higher than 1.85-1.88 V for SPAN at the same current density.Thus doping Te provides a new strategy for increasing the energy density of SPAN. | Ke Wang Yuepeng Guan Zhaoqing Jin Weikun Wang Anbang Wang | 2019 | Journal of Energy Chemistry2019，28，12： | 3 |
| 18 | Decompression alone versus decompression with instrumented fusion for young patients with single-level lumbar disc herniation:a short-term prospective comparative study显示文摘 | Sun Zhuoran Li Weishi Chen Zhongqiang Guo Zhaoqing Qi Qiang Zeng Yan Sun Chuiguo | 2014 | Chinese Medical Journal2014，，11： | 3 |
| 19 | Critical function of DNA methyltransferase 1 in tomato development and regulation of the DNA methylome and transcriptome显示文摘DNA methylation confers epigenetic regulation on gene expression and thereby on various biological processes.Tomato has emerged as an excellent system to study the function of DNA methylation in plant development.To date,regulation and function of DNA methylation maintenance remains unclear in tomato plants.Here,we report the critical function of tomato(Solanum lycopersicum)Methyltransferase 1(Sl MET1)in plant development and DNA methylome and transcriptome regulation.Using CRISPR-Cas9 gene editing,we generated slmet1 mutants and observed severe developmental defects with a frame-shift mutation,including small and curly leaves,defective inflorescence,and parthenocarpy.In leaf tissues,mutations in Sl MET1 caused CG hypomethylation and CHH hypermethylationon a whole-genome scale,leading to a disturbed transcriptome including ectopic expression of many RIN target genes such as ACC2 in leaf tissues,which are normally expressed in fruits.Neither the CG hypomethylation nor CHH hypermethylation in the slmet1 mutants is related to tissue culture.Meanwhile,tissue culture induces non-CG hypomethylation,which occurs more frequently at gene regions than at TE regions.Our results depict Sl MET1-and tissue culture-dependent tomato DNA methylomes,and that Sl MET1 is required for maintaining a normal transcriptome and normal development of tomato. | Yu Yang Kai Tang Tatsiana U Datsenka Wenshan Liu Suhui Lv Zhaobo Lang Xingang Wang Jinghui Gao Wei Wang Wenfeng Nie Zhaoqing Chu Heng Zhang Avtar K HANDa Jian-Kang Zhu Huiming Zhang | 2019 | Journal of Integrative Plant Biology2019，61，12： | 3 |
| 20 | Breast-conserving therapy and modified radical mastectomy for primary breast carcinoma:a matched comparative study显示文摘Background:To compare two types of therapy for primary breast carcinoma,breast-conserving therapy(BCT) and modified radical mastectomy(MRM),in a matched cohort study.Methods:A series of 1,746 patients with primary breast cancer treated with BCT or MRM in a single Chinese institute between January 2000 and February 2009 were analyzed retrospectively to compare their outcomes with respect to the incidence of local recurrence(LR),distant metastasis,and survival.The patients were matched with regard to age at diagnosis,spreading to axillary lymph nodes,hormone receptor status,the use of neoadjuvant chemotherapy and maximal tumor diameter.The match ratio was 1:1,and each arm included 873 patients.Results:The median follow-up period was 71 months.The 6-year disease-free survival(DFS) and 6-year distant disease-free survival(DDFS) rates differed significantly between two groups.The 6-year local recurrence-free survival(LRFS) rates were 98.2% [95% confidence interval(CI):0.973-0.989] in the BCT group and 98.7%(95% CI:0.980-0.994) in the MRM group(P=0.182),respectively.DFS rates in BCT and MRM groups were 91.3%(95% CI:0.894-0.932) and 86.3%(95% CI:0.840-0.886)(P<0.001),respectively,whereas the DDFS rates in BCT and MRM groups were 93.6%(95% CI:0.922-0.950) and 87.7%(95% CI:0.854-0.900)(P<0.001),respectively.Conclusions:BCT in eligible patients is as effective as MRM with respect to local tumor control,DFS and DDFS,and may result in a better outcome than MRM in Chinese primary breast cancer patients. | Lize Wang Tao Ouyang Tianfeng Wang Yuntao Xie Zhaoqing Fan Benyao Lin Jinfeng Li | 2015 | Chinese Journal of Cancer Research2015，27，6： | 3 |
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