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| 1 | Phenotypic variation in Phoebe bournei populations preserved in the primary distribution area显示文摘Phoebe bournei(Hemsl.) Yang is a rare and protected plant in China. This study was conducted to determine the phenotypic variation in this species and to document phenotypic variation within and among populations of P. bournei. Nested analysis of variance, coefficient of variation, multiple comparisons, principal component analysis(PCA) and correlation analysis were used to analyze ten phenotypic traits in ten natural populations of P.bournei from both the northeastern and the primary region of the range of this species. Significant differences among and within populations were observed in leaf and seed phenotypic traits. Variation among populations(34.92%)was greater than that within populations(26.19%). The mean phenotypic differentiation coefficient was 53.77%among populations, indicating that variation among populations comprised the majority of the phenotypic variation of P. bournei. The coefficient of variance(CV) of ten traits varied from 6.44 to 18.45%, with an average of 12.03%.The CV of leaf traits among populations(15.64%) was higher than that of seed traits(8.60%), indicating that seed traits were more stable. The results from CV and PCA indicated that leaf area, leaf length and thousand seed weight were the main factors accounting for the observed phenotypic variations. Significant or highly significant correlations were observed among most leaf and/or in seed phenotypic traits, whereas no significant correlations were observed between phenotypic traits and geographic factors.Based on cluster analysis, the ten populations can be divided into three clusters. These clusters were not a result of geographic distances. | Yingang Li Xinhong Liu Junwei Ma Xiaomian Zhang Li-an Xu | 2018 | Journal of Forestry Research2018，29，1： | 13 |
| 2 | Effect of processing parameters on the densification of an additively manufactured 2024 Al alloy显示文摘Understanding the densification behaviours and formation mechanisms of defects are essential to fabricate high quality and high strength aluminium components using selective laser melting(SLM) technology. In this work, the effects of laser power and scanning speed on the densification, defects evolution and their formation mechanisms in a SLMed 2024 aluminium(Al) alloy were investigated in consideration of the corresponding laser energy input, melting mode transition and microstructural evolution. The results showed that optimizing the processing parameters effectively reduced the porosity level below1% by avoiding the lack of fusion and keyhole melting mode, and minimizing the gas pores. However,optimization of the processing parameters could not eliminate the columnar structure associated with the SLMed 2024 Al alloy, which contributed to the hot-tearing cracks in the SLMed parts. It was found that the dependence of porosity formation on SLM processing parameters was contrary to the crack density. Hence, to further improve the SLM-processability of the 2024 Al alloy it is necessary to develop SLM methods in order avoid the hot-cracking within the optimized processing parameter window associated with the minimum porosity formation. | Qiyang Tan Yingang Liu Zhiqi Fan Jingqi Zhang Yu Yin Ming-Xing Zhang | 2020 | Journal of Materials Science & Technology2020，58，23： | 13 |
| 3 | Effect of Silicon on Growth, Physiology, and Cadmium Translocation of Tobacco (Nicotiana tabacum L.) in Cadmium-Contaminated Soil显示文摘Silicon(Si) offers beneficial effect on plants under cadmium(Cd) stress such as promoting plant growth and increasing resistance to heavy metal toxicity. In this study, a pot experiment was performed to study the role of Si in alleviating Cd toxicity in tobacco(Nicotiana tabacum L.) plants on a yellow soil taken from Guiyang, China. Nine treatments consisting of three concentrations of Cd(0, 1, and 5 mg kg^(-1)) together with three Si levels(0, 1, and 4 g kg^(-1)) were established. Plant growth parameters, Cd concentration,and the malondialdehyde(MDA), chlorophyll, and carotenoid contents were determined 100 d after transplanting of tobacco seedlings.Application of exogenous Si enhanced the growth of tobacco plants under Cd stress. When 5 mg kg^(-1) Cd was added, Si addition at 1 and 4 g kg^(-1) increased root, stem, and leaf biomass by 26.1%–43.3%, 33.7%–43.8%, and 50.8%–69.9%, respectively, compared to Si addition at 0 g kg^(-1). With Si application, the transfer factor of Cd in tobacco from root to shoot under both 1 and 5 mg kg^(-1) Cd treatments decreased by 21%. The MDA contents in the Si-treated tobacco plants declined by 5.5%–17.1% compared to those in the non-Si-treated plants, indicating a higher Cd tolerance. Silicon application also increased the chlorophyll and carotenoid contents by 33.9%–41% and 25.8%–47.3% compared to the Cd only treatments. Therefore, it could be concluded that Si application can alleviate Cd toxicity to tobacco by decreasing Cd partitioning in the shoots and MDA levels and by increasing chlorophyll and carotenoid contents, thereby contributing to lowering the potential health risks of Cd contamination. | LU Yingang MA Jun TENG Ying HE Juny Peter CHRISTIE ZHU Lingjia REN Wenjie ZHANG Manyun Shiping DENG | 2018 | Pedosphere2018，28，4： | 7 |
| 4 | The study of migration of bone mesenchymal stem cells transplanted in intervertebral discs of rabbits and expression of exogenous gene显示文摘Objective: To explore the survival and migration of bone mesenchymal stem cells transplantated in intervertebral disc of rabbits and expression of the exogenic genes. Methods: Thirty-two rabbits were used, A randomized block design was used and discs in the same rabbit were one block,the lumbar discs from L2-3 to L5-6 were randomly divided into blank group, saline group, cell transplantation groupⅠ and cell transplantation groupⅡ. The fluorescence microscopy was used to determine the fluorescence of the maker protein GFP and DNA-PCR was used to analyze the copies of DNA of neomycin-resistant gene at 1, 3, 6, months after transplantation. Results: There was fluorescence in cell transplantation group Ⅰand Ⅱ and none in blank group, saline group at 1, 3, 6 months after transplantation. In cell transplantation groups,the fluorescent distribution was more scatter with time, but no significant difference between cell groups Ⅰand Ⅱ. The test of neomycin resistant gene expressed in cell transplantation group ⅠandⅡ and quantitative analysis showed that there was no significant difference between the cell groups Ⅰand Ⅱ(P > 0.05). Conclusion: The transplanted bone mesenchymal stem cells can survive, migrate and the transfer genes can express efficiently, it suggests that the BMSC therapy may be effective to prevent and treat intervertebral disc degeneration. | Jintang Wang Hong Zhang Yingang Zhang Xiaowei Zhang Meng Li | 2006 | Journal of Nanjing Medical University2006，20，5： | 4 |
| 5 | Clinical diagnosis for discogenic low back pain显示文摘 | Zhang Yingang Guo Tuanmao Gun Xiong | 2009 | Int J Biol Sci2009，5，6： | 1 |
| 6 | Clinical diagnosis for discogenic low back pain显示文摘 | Zhang Yingang Guo Tuanmao Guo Xiong | 2009 | Int J Biol Sci2009，5，6： | 1 |
| 7 | Pathways related to mitochondrial dysfunction in cartilage of endemic osteoarthritis patients in China显示文摘In this paper, we present the first evidence of differences in the mitochondria-related gene expression profiles of adult articular cartilage derived from patients with Kashin-Beck disease and normal controls. The expression of 705 mitochondria-related genes was analyzed by mitochondria-related gene expression analysis and ingenuity pathways analysis. Mitochondria-related gene expression analysis identified 9 up-regulated genes in Kashin-Beck disease based on their average expression ratio. Three canonical pathways involved in oxidative phosphorylation, apoptosis signaling and pyruvate metabolism were identified, which indicate the involvement of mitochondrial dysfunction in the pathogenesis of Kashin-Beck disease. | LI ChunYan WANG WeiZhuo GUO Xlong ZHANG Feng MA WeiJuan ZHANG YinGang LI YouFen BAI YiDong LAMMI Mikko J | 2012 | Science China(Life Sciences)2012，55，12： | 1 |
| 8 | Association between the- 1562C/T polymor-phism of matrix metalloproteinase-9 gene and lumbar disc disease in the young adult popul-ation in north China显示文摘 | Sun Zhengming Liu Miao Zhang Yingang | 2009 | Connect Tissue Res2009，50，3： | 1 |
| 9 | The hydroxyl radical generation and oxidative stress for the earthworm Eisenia fetida exposed to tetrabromobisphenol A显示文摘 | Yingang Xue Xueyuan Gu Xiaorong Wang Cheng Sun Xianghua Xu Jian Sun Baogang Zhang | 2009 | Ecotoxicology2009，，6： | 1 |
| 10 | Association between the - 1562C/T polymorphism of matrix metalloproteinase - 9 gene and lumbar disc disease in the young adult population in north China 显示文摘 | Sun Zhengming Liu Miao Zhang Yingang | 2009 | Connect Tissue Res2009，50，3： | 1 |
| 11 | The hydroxyl radical generation and oxidative stress for the earthworm Eisenia fetida exposed to tetrabromobisphenol A显示文摘 | Yingang Xue Xueyuan Gu Xiaorong Wang Cheng Sun Xianghua Xu Jian Sun Baogang Zhang | 2009 | Ecotoxicology2009，，6： | 1 |
| 12 | 3-Thiomorpholin-8-oxo-8 H -acenaphtho [1,2- b ] pyrrole-9-carbonitrile ( S1 ) derivatives as pan-Bcl-2-inhibitors of Bcl-2, Bcl-x L and Mcl-1显示文摘 | Ting Song Xiangqian Li Xilong Chang Xiaomeng Liang Yan Zhao Guiye Wu Shenghui Xie Pengchen Su Zhiyong Wu Yingang Feng Zhichao Zhang | 2013 | Bioorganic & Medicinal Chemistry2013，，1： | 1 |
| 13 | Association between the-1562 C/T polymorphism of matrix metalloproteinase-9 gene and lumbar disc disease in the young adult population in North China显示文摘 | Sun Zhengming Liu Miao Zhang Yingang | 2009 | Connect Tissue Res2009，50，3： | 1 |
| 14 | An animal model to create intervertebral disc degeneration characterized by radiography and molecular biology显示文摘Objectives:To develop a rabbit model of intervertebral disc degeneration that more exactly simulates the pathological changes of human intervertebral disc degeneration.Methods:Twelve New Zealand white rabbits were utilized to establish three different disc injury models according to the following protocol;group A:anulus punctures were done with a 18-gauge needle at L2-L3 and L5-L6; Group B:intradiscal injection of interleukin-1 IL-1βwith a 23-gauge needle at L3-L4;and Group C:intradiscal injection of phosphate buffer saline(PBS)with a 23-gauge needle at L4-L5.The L1-L2 level was used as a control.Rabbits were killed after 24 weeks.The intervertebral disc height was measured by lateral plain radiographs.After the radiographic measurements were obtained,the interver- tebral discs were removed and analyzed for DNA,sulfated glycosaminoglycan(s-GAG)and water contents of nucleus pulposus.Results: The intervertebral disc height,s-GAG,and water contents in anulus needle punctures were significantly decreased in Group A,but the DNA content in the nucleus pulposus was significantly increased when compared to the control.The significant decrease of disc height and water contents were demonstrated,only the s-GAG and DNA contents did not show a significant difference in Group B when compared to the control.The significant decrease of disc height,s-GAG,water,and DNA contents did not show in Group C when compared to the control.Conclusion:The 18-gauge puncture models produced the most consistent disc degeneration in the rabbit lumbar spine. | Zhengming Sun Miao Liu Yingang Zhang | 2008 | Journal of Nanjing Medical University2008，22，5： | 0 |
| 15 | The effect of spinal cord injury on the expression of TGF-β and TNF-α in rat articular cartilage显示文摘Objective: To observe the expression of TGF-β and TNF-α in the spinal cord injured rat model and discuss the significance of the articular cartilage metabolism. Methods: 36 SD female rats were randomly divided into 2 groups: Rats models of spinal cord injury were implemented by Allen method. T10 laminectomy was performed in the control group. Both groups of rats were killed respectively in 1w, 3w and 6w. Hematoxylin-eosin stain was given to each slice in the model group and control group. Immunohistochemical stain was applied by using ABC method in the expression of TGF-β and TNF-α. Those expressed level were performed in image analysis and statistics process. Results: TGF-β and TNF-α were mainly distributed on the surface layer of the articular cartilage, with a weak expression in control group. The expression of TNF-α in the model group was more significant than that in the control group in the 1w, and still remained an evident difference with that in control group until the 6w(P < 0.05). TGF-β expression of the model group had no remarkable difference with the control group in the 1w(P > 0.05) and prominently became stronger at 6w(P < 0.05). Conclusion: The expression of TNF-α occurred early in the development of spinal cord injury, and the expression of TGF-β became stronger with the revival of spinal neural function. Both expressions were strengthened in articular cartilage in the 3rd week. | Dongqi Wang Min Wang Yingang Zhang Miao Liu | 2007 | Journal of Nanjing Medical University2007，21，3： | 0 |
| 16 | Heterogeneous lamella design to tune the mechanical behaviour of a new cost-effective compositionally complicated alloy显示文摘A heterogeneous lamella(HL)design strategy was applied to manipulate mechanical properties of a new cost-effective Fe_(35)Ni_(35)Cr_(25)Mo_(5)compositionally complicated alloy(CCA).The HL structure was produced by single-step heat treatment(800℃for 1 h)after cold rolling.This HL structure consists of alternative lamellae regions of coarse-grained FCC matrix(5-20μm),and regions containing ultra-fine grains or subgrains(200-500 nm)together with nanoprecipitates(20-500 nm)and annealing twins.As compared with other cost-effective CCAs,the 800℃annealed sample with HL structure demonstrated a comparable tensile property,with yield strength over 1.0 GPa and total elongation of~13%.Formation of the annealing twins and nanoprecipitates decorated HL structure was a result of the concurrent partial recrystallization and precipitation ofσphase at the shear bands with a high density of lattice defects(e.g.high-density dislocation walls and deformation twins).The latter restricted the growth of recrystallized grains,leading to the formation of ultrafine subgrains within the HL structure.The high yield strength resulted from the multistage hetero-deformation induced(HDI)strengthening and precipitation strengthening associated with heterogeneous lamella structures containing nanoprecipitates.The ductility was originated from the coexistence of multiple deformation mechanisms,which started with dislocation slip and formation of stacking faults at the initial stage,followed by nano-twinning at the higher strain level.This HL design strategy,comprising composition and thermomechanical process designs,and the resultant microstructure tuning,open a broader window for the development of cost-effective CCAs with enhanced performance. | Yu Yin Qiyang Tan Qiang Sun Wangrui Ren Jingqi Zhang Shiyang Liu Yingang Liu Michael Bermingham Houwen Chen Ming-Xing Zhang | 2022 | Journal of Materials Science & Technology2022，，1： | 0 |
| 17 | Growth differentiation factor-5 stimulates the growth and anabolic metabolism of articular chondrocytes显示文摘 | Xu Peng Guo Xiong Yao Jianfeng Zhang Yingang Klaus von der Mark | 2005 | 美中国际创伤杂志2005，4，4： | 0 |
| 18 | Laser powder b e d fusion of copper matrix iron particle reinforced nanocomposite with high strength and high conductivity显示文摘Liquid-liquid phase separation,and the resulted solute segregation,during conventional solidification have been a long-term challenge to produce copper(Cu)-iron(Fe)immiscible composites with high strength and high conductivity.The present work reports an effective solution to this issue through laser powder bed fusion(L-PBF)in-situ alloying of Cu-8 wt.%Fe.Microstructure observation showed that the fast cooling within micron-scale melt pools fully eliminated the Fe segregation and therefore the L-PBF fabricated nanocomposite achieved the homogeneous microstructure,which featured equiaxed fine grains around 1μm in size.Ageing of the nanocomposite at 600℃for 1 h enabled precipitation of two types of nanoparticles.One is coarser Fe nanoprecipitates with body-centered cubic(BCC)structure and diam-eter of 100-300 nm,mainly distributing along grain boundaries.The other is smaller Fe nanoprecipitates with face-centered cubic(FCC)structure and diameter of 10-35 nm,being observed within the grains and having coherent interfaces with the Cu matrix.As a result,the aged Cu-Fe nanocomposite achieved tensile strength of 462.9±6.6 MPa with 30.4%±1.7%elongation to failure and 74.5%IACS(International Annealed Copper Standard)electrical conductivity.The formation mechanisms of the nanoprecipitates and the strengthening mechanisms of the nanocomposite are discussed. | Yingang Liu Jingqi Zhang Qiang Sun Meng Li Ming Yan b Xing Cheng Miaoquan Li Ming-Xing Zhang | 2023 | Journal of Materials Science & Technology2023，，3： | 0 |
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