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| 1 | Effect of glial cells on remyelination after spinal cord injury显示文摘Remyelination plays a key role in functional recovery of axons after spinal cord injury.Glial cells are the most abundant cells in the central nervous system.When spinal cord injury occurs,many glial cells at the lesion site are immediately activated,and different cells differentially affect inflammatory reactions after injury.In this review,we aim to discuss the core role of oligodendrocyte precursor cells and crosstalk with the rest of glia and their subcategories in the remyelination process.Activated astrocytes influence proliferation,differentiation,and maturation of oligodendrocyte precursor cells,while activated microglia alter remyelination by regulating the inflammatory reaction after spinal cord injury.Understanding the interaction between oligodendrocyte precursor cells and the rest of glia is necessary when designing a therapeutic plan of remyelination after spinal cord injury. | Hai-feng Wang Xing-kai Liu Rui Li Ping Zhang Ze Chu Chun-li Wang Hua-rui Liu Jun Qi Guo-yue Lv Guang-yi Wang Bin Liu Yan Li Yuan-yi Wang | 2017 | Neural Regeneration Research2017，12，10： | 6 |
| 2 | A pure blue light emitting binaphthyl derivative:Synthesis and properties显示文摘有 3 和 3 个′位置上的分核的联萘衍生物被综合并且经由铃木描绘了偶合反应。在答案最大的排放被作为参考拿 9,10-diphenyl 蒽与 68% 的量子效率在 390 nm 定位,当它与从聚集状态导致固态膜的 104 nm 的 FWHM 被转移到 450 nm 时。玻璃化转变温度(Tg ) 和分解温度被测量分别地,由 DSC 和 TGA 是 184 和 447 ° C。不同于它的光致发光光谱,电镀物品发光光谱在大约 460 nm 和表演达到顶点相应于纯蓝排出物的 69 nm 的 FWHM。刺激电压,发光性和效率最大值是有并列的 CIE 颜色的 5 V, 2953 cd/m2 和 1.37 cd/A (0.16, 0.15 ) ,在 ITO/NPB (40 nm ) 的设备结构 /PY-BN-PY (15 nm )/BPhen (40 nm )/Mg :47 号元素银的化学符号。 | Qing Guo He Zeng Ze Chu Gang Tie Lei An Jun Qin Hong Zhen Lin Feng Lian Bai Jian Gong Cheng Yong Qiu | 2008 | Chinese Chemical Letters2008，19，4： | 4 |
| 3 | Reduced turnover rate of topsoil organic carbon in old-growth forests:a case study in subtropical China显示文摘Background:Old-growth forests are irreplaceable with respect to climate change mitigation and have considerable carbon(C)sink potential in soils.However,the relationship between the soil organic carbon(SOC)turnover rate and forest development is poorly understood,which hinders our ability to assess the C sequestration capacity of soil in old-growth forests.Methods:In this study,we evaluated the SOC turnover rate by calculating the isotopic enrichment factor β(defined as the slope of the regression between ^(13)C natural abundance and log-transformed C concentrations)along 0-30 cm soil profiles in three successional forests in subtropical China.A lower β(steeper slope)is associated with a higher turnover rate.The three forests were a 60-year-old P.massoniana forest(PF),a 100-year-old coniferous and broadleaved mixed forest(MF),and a 400-year-old monsoon evergreen broadleaved forest(BF).We also analyzed the soil physicochemical properties in these forests to examine the dynamics of SOC turnover during forest succession and the main regulators.Results:The β value for the upper 30-cm soils in the BF was significantly(p<0.05)higher than that in the PF,in addition to the SOC stock,although there were nonsignificant differences between the BF and MF.The β value was significantly(p<0.05)positively correlated with the soil recalcitrance index,total nitrogen,and available nitrogen contents but was significantly(p<0.01)negatively correlated with soil pH.Conclusions:Our results demonstrate that SOC has lower turnover rates in old-growth forests,accompanied by higher soil chemical recalcitrance,nitrogen status,and lower soil pH.This finding helps to elucidate the mechanism underlying C sequestration in old-growth forest soils,and emphasizes the important value of old-growth forests among global C sinks. | Xin Xiong Juxiu Liu Guoyi Zhou Qi Deng Huiling Zhang Guowei Chu Ze Meng Deqiang Zhang | 2021 | Forest Ecosystems2021，8，4： | 4 |
| 4 | 季节性干旱驱动亚热带森林的碳积累显示文摘本研究旨在表明处于南亚热带的鼎湖山生物圈保护区的干旱频率和强度正在增加,并说明季节性干旱对亚热带森林碳积累的影响。这是为了应对全球气候变化导致的干旱加剧所带来的威胁开展的一项研究。我们使干旱指数(标准化降水指数、标准降水蒸散发指数、降水距平百分率及自校准帕尔默干旱指数)准确确定干旱期和降水量增加期。此后,将2003至2014年(12年)监测采集的实测涡动通量和土壤含水量数据在干旱期和湿润期之间进行比较,以确定干旱对生态系统碳积累的影响。在本研究所选择的12年期间,干旱的发生时间约占比20%,最强干旱事件和严重程度发生于2012至2013年。研究期间的年平均降水量和气温分别为1404.57±43.2 mm和22.65±0.1°C,与30年记录(1990–2020)相比较,年降水量减少量可达523 mm,而气温则增加了2.55°C。与全球针对大多数森林生态系统研究所发表的数据呈相反趋势,处于中国南亚热带区域的鼎湖山生物圈保护区在60%的干旱期内所监测的森林生态系统记录到显著的碳积累趋势,说明季节性干旱驱动了森林的碳积累。 | Brian Njoroge Yuelin Li Dennis Otieno Shizhong Liu Simin Wei Ze Meng Qianmei Zhang Deqiang Zhang Juxiu Liu Guowei Chu Fasih Ullah Haider John Tenhunen | 2023 | Journal of Plant Ecology2023，16，1： | 0 |
| 5 | Resistive-type sensors based on few-layer MXene and SnO_(2)hollow spheres heterojunctions:Facile synthesis,ethanol sensing performances显示文摘High-performance and low-cost gas sensors are highly desirable and involved in industrial production and environmental detection.The combination of highly conductive MXene and metal oxide materials is a promising strategy to further improve the sensing performances.In this study,the hollow SnO_(2)nanospheres and few-layer MXene are assembled rationally via facile electrostatic synthesis processes,then the SnO_(2)/Ti_(3)C_(2)T_(x)nanocomposites were obtained.Compared with that based on either pure SnO_(2)nanoparticles or hollow nanospheres of SnO_(2),the SnO_(2)/Ti_(3)C_(2)T_(x)composite-based sensor exhibits much better sensing performances such as higher response(36.979),faster response time(5 s),and much improved selectivity as well as stability(15 days)to 100ppm C2H5OH at low working temperature(200°C).The improved sensing performances are mainly attributed to the large specific surface area and significantly increased oxygen vacancy concentration,which provides a large number of active sites for gas adsorption and surface catalytic reaction.In addition,the heterostructure interfaces between SnO_(2)hollow spheres and MXene layers are beneficial to gas sensing behaviors due to the synergistic effect. | Lihua Chu Hao Yan Wanfeng Xie Yuxin Shi Muhammad Hilal Changxu Sun Ze Li Meicheng Li | 2023 | Chinese Chemical Letters2023，34，8： | 0 |
| 6 | Immunomodulatory Nanosystems:Advanced Delivery Tools for Treating Chronic Wounds显示文摘The increasingly aging society led to a rise in the prevalence of chronic wounds(CWs),posing a significant burden to public health on a global scale.One of the key features of CWs is the presence of a maladjusted immune microenvironment characterized by persistent and excessive(hyper)inflammation.A variety of immunomodulatory therapies have been proposed to address this condition.Yet,to date,current delivery systems for immunomodulatory therapy remain inadequate and lack efficiency.This highlights the need for new therapeutic delivery systems,such as nanosystems,to manage the pathological inflammatory imbalance and,ultimately,improve the treatment outcomes of CWs.While a plethora of immunomodulatory nanosystems modifying the immune microenvironment of CWs have shown promising therapeutic effects,the literature on the intersection of immunomodulatory nanosystems and CWs remains relatively scarce.Therefore,this review aims to provide a comprehensive overview of the pathogenesis and characteristics of the immune microenvironment in CWs,discuss important advancements in our understanding of CW healing,and delineate the versatility and applicability of immunomodulatory nanosystems-based therapies in the therapeutic management of CWs.In addition,we herein also shed light on the main challenges and future perspectives in this rapidly evolving research field. | Xiangyu Chu Yuan Xiong Samuel Knoedler Li Lu Adriana CPanayi Michael Alfertshofe Dongsheng Jiang Yuval Rinkevich Ze Lin Zhiming Zhao Guandong Daia Bobin Mi Guohui Liu | 2023 | Research2023，，4： | 0 |
| 7 | Relevances of microfilament and microtubule to the adhesion properties of the HCC onto the Collagen IV/ Laminin coated surface显示文摘The adhesion properties of both hepatocytes and hepatocellular carcinoma cells (HCCs) onto the Coll IV/laminin coated surface were measured by means of micropipette aspiration technique. Further,relevances of microfilament and microtubule systems to the adhesion properties of the HCCs on Coll IV/laminin coated dishes were investigated by using cytoskeletal agents colchicine and cytochalasin D. The results showed: cytochalasin D, which inhibits microfilament polymerization, had great inhibitory effect on adherence of both kinds of cells to Coll IV/ Laminin substratum (about 70%~90%). At the same time, HCCs extension obviously decreased and focal contacts almost vanished after being treated with cytochalasin D, in contrast, there was no significant effect on the formation of extention of hepatocytes. Colchicine, which inhibits microtubular polymerization, had different effects on both cells: Compared with untreated groups, the adhesion forces of HCC cells decreased and those of hepatocytes increased. These data suggested that, in these tumor cells, microfilament system are crucial for adherence, and abnormal cytoskeletons of tumor cells may be basis of their abnormal adhesion properties. | SHAO Kai feng,WU Ze zhi ①, WANG Bo chu, LONG Mian, CAI Shao xiBioengineering college, Chongqing University, Chongqing 400044, China | 2000 | Chinese Journal of Biomedical Engineering(English Edition)2000，9，2： | 0 |
| 8 | Solid electrolyte interphase on anodes in rechargeable lithium batteries显示文摘Highly safe and efficient rechargeable lithium batteries have become an indispensable component of the intelligent society powering smart electronics and electric vehicles.This review summarizes the formation principle,chemical compositions,and theoretical models of the solid electrolyte interphase(SEI)on the anode in the lithium battery,involving the functions and influences of the electroactive materials.The discrepancies of the SEI on different kinds of anode materials,as well as the choice and design of the electrolytes are detailedly clarified.Furthermore,the design strategies to obtain a stable and efficient SEI are outlined and discussed.Last but not least,the challenges and perspectives of artificial SEI technology are briefly proposed for the development of high-efficiency batteries in practice. | Lihua Chu Yuxin Shi Ze Li Changxu Sun Hao Yan Jing Ma Xuchen Li Chaofeng Liu Jianan Gu Kai Liu Lehao Liu Bing Jiang Yingfeng Li Meicheng Li | 2023 | Nano Research2023，16，9： | 0 |
| 9 | Eight Zhes Decoction ameliorates the lipid dysfunction of nonalcoholic fatty liver disease using integrated lipidomics, network pharmacology and pharmacokinetics显示文摘Nonalcoholic fatty liver disease(NAFLD)has developed into the most common chronic liver disease and can lead to liver cancer.Our laboratory previously developed a novel prescription for NAFLD,“Eight Zhes Decoction”(EZD),which has shown good curative effects in clinical practice.However,the pharmacodynamic material basis and mechanism have not yet been revealed.A strategy integrating lipidomics,network pharmacology and pharmacokinetics was used to reveal the active components and mechanisms of EZD against NAFLD.The histopathological results showed that EZD attenuated the degrees of collagen deposition and steatosis in the livers of nonalcoholic steatofibrosis model mice.Furthermore,glycerophospholipid metabolism,arachidonic acid metabolism,glycerolipid metabolism and linoleic acid metabolism with phospholipase A2 group IVA(PLA2G4A)and cytochrome P450 as the core targets and 12,13-cis-epoxyoctadecenoic acid,12(S)-hydroxyeicosatetraenoic acid,leukotriene B4,prostaglandin E2,phosphatidylcholines(PCs)and triacylglycerols(TGs)as the main lipids were found to be involved in the treatment of NAFLD by EZD.Importantly,naringenin,artemetin,canadine,and bicuculline were identified as the active ingredients of EZD against NAFLD;in particular,naringenin reduces PC consumption by inhibiting the expression of PLA2G4A and thus promotes sufficient synthesis of very-low-density lipoprotein to transport excess TGs in the liver.This research provides valuable data and theoretical support for the application of EZD against NAFLD. | Yuping Zhou Ze Dai Kaili Deng Yubin Wang Jiamin Ying Donghui Chu Jinyue Zhou Chunlan Tang | 2023 | Journal of Pharmaceutical Analysis2023，13，9： | 0 |
| 10 | Modulation of Electrochemical Oscillations by Specific Adsorption of Cl- during the Electrooxidation of Methanol on Pt Electrode显示文摘Potential oscillation during the electrocatalytic oxidation of methanol can be modulated by the specific adsorption of Cl- on the platinum electrode, which suppresses the electrocatalytic oxidation of methanol, and makes the cross cycle in the cyclic voltammogram become smaller and finally disappear with the increase of Cl- concentration. The method is also applicable to the electrocatalytic oxidation of other small organic molecules. | Ze Lin LI *, Ji Hua HUANG, Xiao Ming XIAO, Yue ZENG, Xia CHU Department of Chemistry, Hunan Normal University, Changsha 410081 | 2002 | Chinese Chemical Letters2002，13，3： | 0 |
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