|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 不同长度和化学预处理方式对稻草厌氧发酵产甲烷特性的影响显示文摘我国能源需求的急剧增加促使国家大力发展可再生能源,甲烷作为极具应用前景的可再生能源之一,其发展利用及相关技术受到广泛关注。为了有效利用秸秆等农作物废弃物,提高其发酵产甲烷能力,本文以反刍动物瘤胃液为接种物,体外批次发酵法研究了不同长度(1 mm、2mm、4 mm和8 mm)及预处理方式(4%尿素、4%氨和4%氢氧化钠处理)对稻草发酵产甲烷能力的影响。不同长度稻草体外发酵试验结果显示:当稻草长度为1 mm时,总产气量及甲烷产量最低,分别为58.16 mL和28.60 mL;稻草长度为8 mm时,甲烷产量最高,为32.34 mL;稻草长度从1 mm增加至8 mm时,甲烷产量也逐渐升高,但稻草长度为4 mm与8 mm间的甲烷产量没有显著差异。不同预处理方式对稻草甲烷产量的研究结果显示:氨处理时,稻草体外发酵甲烷产量最高,为41.51 mL,但与氢氧化钠处理的稻草相比,甲烷产量没有显著差异,尿素处理时稻草发酵产甲烷量最低,仅为28.81 mL,显著低于氨与氢氧化钠处理时稻草的甲烷产量;氨处理时稻草发酵总产气量也最高,为109.51 mL,但与其他两个处理相比差异不显著;与未经化学处理的稻草相比,氨和氢氧化钠处理均能提高稻草体外发酵时的甲烷产量。研究结果表明:片段长度与预处理方式都能影响稻草厌氧发酵产甲烷的能力,本文研究结果为合理有效提高稻草厌氧发酵产甲烷能力提供了可行途径。 | 朱益志 Zaw Lin 成艳芬 朱伟云 | 2013 | 畜牧与兽医2013，45，11： | 4 |
| 2 | Hepatitis C virus therapy with peg-interferon and ribavirin in Myanmar: A resource-constrained country显示文摘AIM To investigate peg-interferon(peg-IFN) and ribavirin(RBV) therapy in Myanmar and to predict sustained virologic response(SVR).METHODS This single-center, open-label, study was conducted in Myanmar between 2009 and 2014. A total of 288 patients infected with HCV genotypes 1, 2, 3 and 6 were treated with peg-IFN alpha-2a(180 μg/wk) or alpha-2b(50 to 100 μg as a weight-based dose) and RBV as a weight-based dose(15 mg/kg/d). Treatment duration was 48 wk for genotypes 1 and 6, 24 wk for genotype 2, and 24 or 48 wk for genotype 3 based on rapid virologic response(RVR). Those co-infected with hepatitis B received 48 wk of therapy.RESULTS Overall, SVR was achieved for 82% of patients and the therapy was well tolerated. All patients achieved SVR at equivalent rates regardless of HCV genotype(P = 0.314). Low fibrosis scores(P < 0.001), high baseline albumin levels(P = 0.028) and low baseline viral loads(P = 0.029) all independently predicted SVR. On the other hand, IL-28 B TT and CC genotypes were not found to significantly predict SVR(P = 0.634; P = 0.618). Among those who completed treatment, the occurrence of RVR showed a > 96% positive predictive value for achieving SVR. Treatment duration did not significantly impact the likelihood of achieving SVR for patients infected with genotype 3 HCV(P = 0.371). The most common adverse events were fatigue(71%) and poor appetite(60%). Among patients with genotype 3 HCV, more patients in the 48-wk treatment group required erythropoietin than in the 24-wk treatment group(61.1% vs 49.2%).CONCLUSION SVR rates were high with peg-IFN and RBV therapy in Myanmar. Fibrosis scores, baseline albumin, HCV RNA levels and RVR independently predicted SVR. | Naomi Khaing Than Hlaing Debolina Banerjee Robert Mitrani Soe Htet Arker Kyaw San Win Nyan Lin Tun Zaw Thant Khin Maung Win K Rajender Reddy | 2016 | World Journal of Gastroenterology2016，22，43： | 2 |
| 3 | Thalifaberidine,a cytotoxic aporphine-benzyl-isoquinline alkaloid from Thalictrum faberi显示文摘 | Lin L Z Hu S F Zaw K | | 0，，10： | 1 |
| 4 | Mapping and modelling the impact of mass drug adminstration on filariasis prevalence in Myanmar显示文摘Background:Lymphatic filariasis(LF)is endemic in Myanmar and targeted for elimination.To highlight the National Programme to Eliminate Lymphatic Filariasis(NPELF)progress between 2000 and 2014,this paper describes the geographical distribution of LF,the scale-up and impact of mass drug administration(MDA)implementation,and the first evidence of the decline in transmission in five districts.Methods:The LF distribution was determined by mapping historical and baseline prevalence data collected by NPELF.Data on the MDA implementation,reported coverage rates and sentinel site surveillance were summarized.A statistical model was developed from the available prevalence data to predict prevalence at township level by year of measurement.Transmission assessment survey(TAS)methods,measuring antigenemia(Ag)prevalence in children,were used to determine whether prevalence was below a level where recrudescence is unlikely to occur.Results:The highest baseline LF prevalence was found in the Central Valley region.The MDA implementation activities scaled up to cover 45 districts,representing the majority of the endemic population,with drug coverage rates ranging from 60.0%to 98.5%.Challenges related to drug supply and local conflict were reported,and interrupted MDA in some districts.Overall,significant reductions in LF prevalence were found,especially after the first 2 to 3 rounds of MDA,which was supported by the corresponding model.The TAS activities in five districts found only two Ag positive children,resulting in all districts passing the critical threshold.Conclusion:Overall,the Myanmar NPELF has made positive steps forward in the elimination of LF despite several challenges,however,it needs to maintain momentum,drawing on international stakeholder support,to aim towards the national and global goals of elimination. | Ni Ni Aye Zaw Lin Khin Nan Lon Nay Yi Yi Linn Thet Wai Nwe Khin Mon Mon Kapa Ramaiah Hannah Betts Louise A.Kelly-Hope | 2018 | Infectious Diseases of Poverty2018，7，1： | 1 |
| 5 | 棉铃虫APN基因家族系统进化与功能分析显示文摘氨肽酶N(APN)是锌金属蛋白酶M1家族的成员,鳞翅目昆虫中肠刷状缘膜囊泡(brush border membrane vesicles,BBMV)细胞膜上的APN不仅在蛋白消化吸收过程中起着重要的作用,而且是Bt的重要受体蛋白。本研究通过PCR技术克隆得到7条棉铃虫APN基因全长序列,HaAPN1~7(Genbank登录号为MT002819~MT002825)。经生物信息学分析,HaAPN1~7全长为2592~3099 bp,编码863~1032个氨基酸,分子量为110~115 kDa,等电点为4.7~6.4,N端信号肽为15~20 aa。系统进化分析结果表明,HaAPN1~7分属于Class 1~7类别。RT−qPCR结果表明,在敏感棉铃虫5龄幼虫中肠中APN2的表达量最高,APN7的表达量最低;Cry1Ac抗性品系棉铃虫中各类APN的表达趋势与敏感品系一致。取食Cry1Ac、Cry2Ab和Vip3Aa蛋白后棉铃虫中肠APN活性显著降低,取食Cry1Ac和Vip3Aa蛋白后中肠液和BBMV中APN活性都显著降低,而取食Cry2Ab蛋白后只有BBMV上APN活性显著降低;棉铃虫对Cry1Ac、Cry2Ab和Vip3Aa产生耐受性后,中肠液和BBMV中APN活性也都发生显著变化。因此,不同类别的棉铃虫APN在Bt的杀虫机制中可能起到不同的作用,APN活性变化可能与Bt蛋白的降解及抗性演化相关。 | 牛琳琳 ZAW Lin Naing 张彩虹 EI Thinzar Soe 梁革梅 | 2021 | 中国生物防治学报2021，37，1： | 1 |
| 6 | 棉铃虫四个丝氨酸蛋白酶抑制剂基因的克隆与表达分析显示文摘为明确棉铃虫Helicoverpa armigera丝氨酸蛋白酶抑制剂(serine protease inhibitor,serpin)的种类及其表达特性,利用PCR技术克隆棉铃虫的serpin基因,使用生物信息学软件预测其结构并进行系统进化分析,采用实时荧光定量PCR(real time quantitative PCR,RT-qPCR)技术比较serpin基因在棉铃虫不同发育阶段和组织中的表达量及取食Cry1Ac后其表达量的变化。结果表明,共获得serpin-a、serpin-b、serpin-c、serpin-e四个棉铃虫serpin基因,全长为1119~1254 bp,编码373~418个氨基酸,均包含一段具有反应中心环的保守结构域,且与斜纹夜蛾Spodoptera litura、草地贪夜蛾S.frugiperda等鳞翅目昆虫serpin的同源性较高。serpin-a和serpin-e在棉铃虫4龄幼虫期的表达量最高,serpin-b和serpin-c分别在成虫期和蛹期表达量最高。serpin-a在中肠和围食膜中表达量最高,serpin-b在头、中肠和表皮中表达量最高,serpin-c在头部表达量最高,serpin-e在中肠和血淋巴中的表达量显著高于其他组织。棉铃虫取食低浓度Cry1Ac后,中肠的serpin-b和serpin-e的表达量显著增加。推测不同serpin基因在棉铃虫不同发育时期和组织中可能发挥不同的作用,其中serpin-b和serpin-e可能参与棉铃虫对Cry1Ac的解毒过程。 | 张彩虹 Zaw Lin Naing Ei Thinzar Soe 梁革梅 | 2021 | 植物保护学报2021，48，5： | 0 |
| 7 | The effect of pharmaceutical care in the elderly patients with type 2 diabetes mellitus显示文摘Pharmaceutical care plays a crucial role in reducing mortality and morbidities of the patients.A hospital based quasiexperimental study was conducted with elderly patients with type 2 diabetes who attended at the diabetes clinic of No.(2)Military Hospital(500-Bedded)in Myanmar from April 2013 to February 2014.The aim of this study was to evaluate the effect of pharmaceutical care in elderly patients with type 2 diabetes mellitus.A total of 52 respondents enrolled in this study.The clinical outcomes and quality of life of patients before and eight months after intervention were assessed.Pharmaceutical care program was implemented as intervention.Of the total number of respondents,52 drug related problems were identified. | Win Myat Maw Mi Mi Saw Theingi Kyaw Khin Ohnmar Kyaing Zaw Min Latt KyawZaw Lin Aung PyaePhyo | 2016 | Asian Journal of Pharmaceutical Sciences2016，11，1： | 0 |
| 8 | Participation of private general practitioners in disease management of malaria in Myanmar显示文摘Objective:Myanmar has been trying to improve the disease management of malaria through public health services. The involvement of private general practitioners(GPs) is recognized as one of the key contributory issues in malaria control,but no one has yet made an attempt to study the efficiency of their role.This study aimed to assess the participation of GPs in improvement of disease management.Methods:The study was conducted with all 32 GPs practicing at three randomly selected townships with high malaria load situated in Upper Myanmar from June 2006 to March 2007 using a pretest-posttest design to assess their knowledge of the disease management prior to and after intervention.The intervention package consisted of a one-day workshop on diagnosis and treatment of malaria and the supply of facilities for microscopy.Questionnaires filled in before and after tests were compared to assess the change of knowledge after the intervention.Diagnosis and treatment practice during the study period was analysed by review of registers kept by GPs,together with a follow-up survey of their patients for the reliability of data.Results:An overall improvement of knowledge was observed and significant changes were apparent for three variables:the criteria for referral of severe malaria,the effect of incomplete treatment and recommended treatment of Plasmodium vivax.Pre-test results showed that only 65.6%of GPs perceived microscopy or Rapid Diagnostic Test kits(RDTs) for confirmation of malaria necessary,while only 15.6%and 40.6%of the GPs knew the recommended treatments of falciparum and vivax malaria,respectively. However,after intervention 92%of the patients were diagnosed as malaria by RDTs and 3%by microscopy throughout the study.The GPs prescribed artemisinin-based combination therapy(ACTs) to 95%of confirmed falciparum cases and treated 82.4%of RDT confirmed falciparum negatives with chloroquine and primaquine.Concurrent with our study,an international NGO,Population Service International,supplied GPs with RDTs and ACTs at subsidized rate which was helpful.Conclusion:The study suggests that participation of GPs may help improve the disease management of malaria and thus assist in the country’s effort to control ma- laria. | Thein Tun Zaw Win Tun Hla Soe Tint Khin Lin Thar Tun Kyaw Moe Kyaw Myint | 2009 | Asian Pacific Journal of Tropical Medicine2009，2，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员