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| 1 | Screening for main components associated with the idiosyncratic hepatotoxicity of a tonic herb, Polygonum multiflorum显示文摘典型药用的植物的主要成分,蓼 multiflorum (用汉语的 Heshouwu ) ,那导致特质的肝损害仍然保持不清楚。我们的以前的工作证明了有 lipopolysaccharide (LPS ) 的无毒的剂量和 Heshouwu 的治疗学的剂量的 cotreatment 能在老鼠导致肝损害,而独唱治疗不能导致看得见的损害。在现在的工作,用成分大美人和敲门在里面策略,我们发现 Heshouwu 的乙醇醋酸盐(EA ) 摘录在对待 LPS 的老鼠显示了可比较的特质的 hepatotoxicity 到整个摘录。结果显示血浆丙氨酸 aminotransferase, aspartate aminotransferase,和肝 histologic 的重要举起变化,而另外的分开的部分没能导致肝损害。有另外的分开的部分的 EA 摘录的混合在对待 LPS 的老鼠导致了可比较的特质的 hepatotoxicity 到整个摘录。化学分析进一步揭示了那 2,3,5,4-tetrahydroxy trans-stilbene-2-O -- 配糖物(trans-SG ) 和它的 cis 异构体是在 EA 的二主要混合物摘录。而且,孤立的 cis- ,并且不它的 trans 异构体,显示的可比较的特质的 hepatotoxicity 到在对待 LPS 的老鼠的 EA 摘录。cis-SG 的更高的内容从与收集的将军相比与 Heshouwu 联系的实际的肝沉醉病人在 Heshouwu 白酒或准备被检测样品。另外,血浆 metabolomics 分析证明 cis-SG-disturbing 充实显著地不同于的小径在对待 LPS 的老鼠的 trans-SG。所有这些结果建议 cis-SG 仔细与 Heshouwu 的特质的 hepatotoxicity 被联系。认为 trans-SG 的 cis-trans 异构化被紫外光或日光调停,我们的调查结果为在药发现控制 photoisomerization 并且为 Heshouwu 和芪相关的药的临床的使用用作参考。 | Chunyu Li Ming Niu Zhaofang Bai Congen Zhang Yanling Zhao Ruiyu Li Can Tu Huifang Li Jing Jing Yakun Meng Zhijie Ma Wuwen Feng Jinfa Tang Yun Zhu Jinjie Li Xiaoya Shang Zhengsheng Zou Xiaohe Xiao Jiabo Wang | 2017 | Frontiers of Medicine2017，11，2： | 41 |
| 2 | A novel micro-straw for cryopreservation of sma number of human spermatozoon显示文摘很少精子的 Cryopreservation 仍然是为男富饶保藏的主要挑战。这研究报导使用一新微稻草(LSL 稻草) 为为 intracytoplasmic 精子注射(ICSI ) 冻结很少精子。从 22 个肥沃的施主的精液样品被收集,并且每件精液样品被冲淡并且在 1:1 的比率与 cryoprotectant 混合了,然后结冰使用象 LSL 稻草(50-100 l ) 那样的三根不同稻草,传统 0.25 ml 和 0.5 根 ml 稻草。为结冰,所有稻草与液体氮被熏蒸,与直接归结为 130-140 的温度 ??? , | Feng Liu Sha-Sha Zou Yong Zhu Can Sun Yu-Fei Liu Shan-Shan Wang Wen-Bo Shi Jing-Jing Zhu Yong-Hua Huang Zheng Li | 2017 | Asian Journal of Andrology2017，19，3： | 19 |
| 3 | Values of the Wells and Revised Geneva Scores Combined with D-dimer in Diagnosing Elderly Pulmonary Embolism Patients显示文摘 | Dan-Jie Guo Can Zhao Ya-Dan Zou Xu-Hang Huang Jing-Min Hu Lin Guo | 2015 | Chinese Medical Journal2015，，8： | 14 |
| 4 | A chlorinated non-fullerene acceptor for efficient polymer solar cells显示文摘Improving the performance and reducing the manufacturing costs are the main directions for the development of organic solar cells in the future.Here,the strategy that uses chemical structure modification to optimize the photoelectric properties is reported.A new narrow bandgap(1.30 eV)chlorinated non-fullerene electron acceptor(Y15),based on benzo[d][1,2,3] triazole with two 3-undecylthieno[2’,3’:4,5] thieno[3,2-b] pyrrole fused-7-heterocyclic ring,with absorption edge extending to the near-infrared(NIR) region,namely A-DA’D-A type structure,is designed and synthesized.Its electrochemical and optoelectronic properties are systematically investigated.Benefitting from its NIR light harvesting,the fabricated photovoltaic devices based on Y15 deliver a high power conversion efficiency(PCE) of 14.13%,when blending with a wide bandgap polymer donor PM6.Our results show that the A-DA’D-A type molecular design and application of near-infrared electron acceptors have the potential to further improve the PCE of polymer solar cells(PSCs). | Mei Luo Can Zhu Jun Yuan Liuyang Zhou M.L.Keshtov D.Yu Godovsky Yingping Zou | 2019 | Chinese Chemical Letters2019，30，12： | 5 |
| 5 | Research on paleo-fluid sources and hydrocarbon preservation conditions in marine carbonates inthe central Yangtze,China显示文摘87Sr/86Sr,δ18O andδ13C ratios of calcite,dolomite,gypsum filling vugs and fissures in marine carbonates and their host rocks from the Sinian to the middle Triassic,are employed to trace the possible source and migration path of key fluids related to development of hydrocarbon,hydrocarbon preservation condition are then discussed further.Comprehensive research,based on the paleo-fluid,the property of formation water and the deformation intensity etc.,indicates that the preservation conditionsin the Shizhu synclinorium zone and Fangdoushan anticlinorium zone are the most predominant in the central Yangtze.Three sets of fluid systems in the Shizhu synclinorium zone are identified.Little fluid exchange occurs between the upper-middle fluid system and the lower fluid system,so two independent preservation units have developed.Both the Permian and the Triassic in the upper preservation unitsand the Dengying Formation of the Sinian and the lower Cambrian in the lower preservation units havegood preservation conditions.The preservation condition in the lower association(Z-S)located in the Huaguoping synclinorium zone in the western Hubei and Hunan is better than that in other tectonic units,where the fluids in the lower association migrated vertically across strata when the fluid isolating intervalswere destroyed,the regional seals are absent and the conditions for the preservation of hydrocarbon accumulations are totally destroyed.The preservation condition is increasingly more favorable from the western Jiangxi and Hunan to the western Hubei&eastern Chongqing on the whole. | Wang Guozhi Xu Guosheng Yuan Haifeng Hu Xiaofeng Zou Can | 2011 | Petroleum Science2011，8，3： | 4 |
| 6 | Whole-Genome Sequences Analysis Displays Relationship of SARS-CoV-2 Delta Variant Between Four Local Cases and Passengers of a Flight from South Africa—Shenzhen City,Guangdong Province,China,June 2021显示文摘On June 14,2021,a customs officer(Case A)went to the infirmary at Baoan International Airport in Shenzhen due to a runny nose and fever.He was admitted to the Central Hospital of Baoan immediately.This patient preliminarily tested positive for coronavirus disease 2019(COVID-19)infection,caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),using a quantitative realtime reverse transcription polymerase chain reaction(qRT-PCR)method in this hospital.Then,a mixed specimen of nasopharyngeal swab. | Yaqing He Renli Zhang Qiuying Lyu Bo Peng Shujiang Mei Ying Sun Dongfeng Kong Chaoqiong Peng Ziquan Lyu Xinyi Wei Can Zhu Xiaoliang Xiao Shimin Li Qingju Lu Jiancheng Chen Hang Zhang Xuan Zou Tiejian Feng Long Chen | 2021 | China CDC weekly2021，3，50： | 3 |
| 7 | EUS-guided celiac ganglion irradiation with iodine-125 seeds for pain control in pancreatic carcinoma: a prospective pilot study显示文摘 | Kai-Xuan Wang Zhen-Dong Jin Yi-Qi Du Xian-Bao Zhan Duo-Wu Zou Yan Liu Dong Wang Jie Chen Can Xu Zhao-Shen Li | 2012 | Gastrointestinal Endoscopy2012，，5： | 2 |
| 8 | Randomized controlled study of a diagnosis and treatment plan for moderate coronavirus disease 2019 that integrates Traditional Chinese and Western Medicine显示文摘OBJECTIVE:To investigate the clinical efficacy and safety of a diagnosis and treatment plan for moderate coronavirus disease 2019(COVID-19)that integrates traditional Chinese(TCM)and western medicine.METHODS:One hundred twenty patients with moderate COVID-19 were randomized 1∶2 to the control group(n=40)and experimental group(n=80).Both groups received conventional western medicine treatment,and the experimental group also received TCM decoction.Over a 2-week period from diagnosis,we observed the time to clinical recovery(TTCR),rate of improvement on lung computed tomography(CT)imaging,time to defervescence,cough remission time,hospital discharge rate,average hospitalization stay,modified Medical Research Council(m MRC)scale score,clinical cure rate,laboratory findings,incidence of progression to severe or critical disease,and adverse events.RESULTS:Among 120 enrolled patients,108 completed the study.The baseline data did not differ between the experimental and control groups(all P>0.05).After treatment,the TTCR,rate of lung CT imaging improvement,time to defervescence,cough remission time,hospital discharge rate,average hospitalization stay(among discharged patients),m MRC scale score,clinical cure rate,and rates of normal values for laboratory findings were better in the experimental group than in the control group(P<0.05 or<0.01).The incidence of progression to severe or critical disease and the incidence of adverse events did not differ between the two groups(P>0.05).CONCLUSION:The diagnosis and treatment plan integrating Chinese and western medicine showed improved clinical efficacy compared with western medicine alone for patients with moderate COVID-19 and is worthy of clinical promotion and application. | XIA Wenguang ZHENG Chanjuan ZHANG Jixian HUANG Min LI Qinglin DUAN Can LI Zhengliang FAN Cunyu ZOU Yilong XU Bo YANG Fengwen LIU Qingquan | 2022 | Journal of Traditional Chinese Medicine2022，42，2： | 2 |
| 9 | Decomposition of energy-related CO 2 emission in China: 1957–2000显示文摘 | Can Wang Jining Chen Ji Zou | 2004 | Energy2004，，1： | 2 |
| 10 | Expression of Oct4 in HCC and modulation to wnt/β-catenin and TGF-β signal pathways显示文摘 | FangJun Yuan Wenbo Zhou Can Zou Zhiyun Zhang Hongsheng Hu Zongqing Dai YouShun Zhang | 2010 | Molecular and Cellular Biochemistry (-)2010，，1： | 2 |
| 11 | Composition and Origin of Ferromanganese Crusts from Equatorial Western Pacific Seamounts显示文摘In the equatorial western Pacific, iron-manganese oxyhydroxide crusts(Fe-Mn crusts) and nodules form on basaltic seamounts and on the top of drowned carbonate platform guyots that have been swept free of pelagic sediments. To date, the Fe-Mn crusts have been considered to be almost exclusively of abiotic origin. However, it has recently been suggested that these crusts may be a result of biomineralization. Although the Fe-Mn crust textures in the equatorial western Pacific are similar to those constructed by bacteria and algae, and biomarkers also document the existence of bacteria and algae dispersed within the Fe-Mn crusts, the precipitation, accumulation and distribution of elements, such as Fe, Mn, Ni and Co in Fe-Mn crusts are not controlled by microbial activity. Bacteria and algae are only physically incorporated into the crusts when dead plankton settle on the ocean floor and are trapped on the crust surface. Geochemical evidence suggests a hydrogenous origin of Fe-Mn crusts in the equatorial western Pacific, thus verifying a process for Fe-Mn crusts that involves the precipitation of colloidal phases from seawater followed by extensive scavenging of dissolved trace metals into the mineral phase during crust formation. | WANG Guozhi JANSA Luba CHU Fengyou ZOU Can SUN Guosheng | 2015 | Journal of Ocean University of China2015，14，2： | 2 |
| 12 | A LED driver with dynamic high frequency sinusoidal bus voltage regulation for multi-string applications显示文摘 | Luo Quanming Zhi Shubo Zou Can | 2014 | IEEE Transactions on Power Electronics2014，29，1： | 1 |
| 13 | Decomposition of energy- related CO2 emission in China: 1957 - 2000 显示文摘 | Can Wang Jining Chen Ji Zou | 2005 | Energy2005 (30) : 73 - 832005，2005，30： | 1 |
| 14 | Decomposition of energy-re- lated CO2 emission in China: 1957-2000 显示文摘 | WANG Can CHEN Jining ZOU Ji | 2005 | Energy2005，，30： | 1 |
| 15 | Decomposition of energy- related CO2 emission in China : 1957- 2000 显示文摘 | WANG Can CHEN Jining ZOU Ji | 2005 | Energy2005，30，1： | 1 |
| 16 | Decomposition of Energy - related CO2 Emission in China: 1957 - 2000 显示文摘 | Wang Can Chen Jining Zou Ji | 2005 | Energy2005，，30： | 1 |
| 17 | Decomposition of energy-related CO2 emission in China:1957-2000显示文摘 | Wang Can Chen Jining ZOU Ji | 2005 | Energy2005，30，： | 1 |
| 18 | Decomposition of energy-related CO2 emission in China: 1957-2000显示文摘 | WANG Can CHEN Ji-ning ZOU Ji | 2005 | Energy2005，30，： | 1 |
| 19 | A time domain three-dimensional sono-elastic method for ships' vibration and acoustic radiation analysis in water显示文摘The classical three-dimensional hydroelasticity of ships is extend to include the effect of fluid compressibility, which yields the three-dimensional sono-elasticity of ships. To enable the predictions of coupled transient or nonlinear vibrations and acoustic radiations of ship structures, a time domain three-dimensional sono-elastic analysis method of acoustic responses of a floating structure is presented. The frequency domain added mass and radiation damping coefficients of the ship are first calculated by a three-dimensional frequency domain analysis method, from which a retardation function is derived and converted into the generalized time domain radiation force through a convolution integral. On this basis the generalized time domain sono-elastic equations of motion of the ship hull in water are established for calculation of the steady-state or transient-state excitation induced coupled vibrations and acoustic radiations of the ship. The generalized hydrodynamic coefficients, structural vibrations and underwater acoustic radiations of an elastic spherical shell excited by a concentrated pulsating force are illustrated and compared with analytical solutions with good agreement. The numerical results of a rectangular floating body are also presented to discuss the numerical error resultant from truncation of the upper integration limit in the Fourier integral of the frequency domain added mass coefficients for the retardation function. | Ming-song Zou You-sheng Wu Can Sima Shu-xiao Liu | 2019 | Journal of Hydrodynamics2019，31，3： | 1 |
| 20 | Highly sensitive glucose biosensor based on one-pot biochemical preoxidation and electropolymerization of 2, 5-Dimercapto-1,3, 4-thiadiazole in glucose oxidase-containing aqueous suspension显示文摘 | Fu Yingehun Zou Can Xie Qingji | 2009 | J Phys Chem B2009，113，5： | 1 |
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