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| 1 | Reovirus,isolated from SARS patients显示文摘Beijing has been severely affected by SARS, and SARS-associated coronavirus has been confirmed as its cause. However, clinical and experimental evidence implicates the possibility of co-infection. In this report, reovirus was isolated from throat swabs of SARS patients, including the first case in Beijing and her mother. Identification with the electron microscopy revealed the characteristic features of reovirus. 24 of 38 samples from other SARS cases were found to have serologic responses to the reovirus. Primers designed for reovirus have amplified several fragments of DNA, one of which was sequenced (S2 gene fragment), which indicates it as a unique reovirus (orthoreovirus). Preliminary animal experiment showed that inoculation of the reovirus in mice caused death with atypical pneumonia. Nevertheless, the association of reovirus with SARS outbreak requires to be further investigated. | DUANQing ZHUHong YANGYi LIWeihua ZHOUYusen HEJun HEKun ZHANGHaojie ZHOUTao SONGLihua GANYonghua TANHua JINBaofeng LIHuiyan ZUOTingting CHENDehui ZHANGXuemin | 2003 | Chinese Science Bulletin2003，48，13： | 16 |
| 2 | ATF4 is directly recruited by TLR4 signaling and positively regulates TLR4-trigged cytokine production in human monocytes显示文摘像使用费的受体(TLR ) 是主人防卫系统的哨兵,它认出很多微生物引起的病原体。主机防卫系统可能是低效的或如果由 TLR 和随后的被触发 TLR 的 cytokine 生产的微生物引起的识别是 deregulated,煽动性的疾病可以发展。激活抄写因素 4 (ATF4 ) , ATF/CREB 抄写因素家庭的一个成员,是参予几个 pathophysiological 过程的一个重要因素。在这份报告,我们发现 ATF4 也涉及调停 TLR 的天生的有免疫力的反应,它参予 TLR4 信号 transduction 并且调停许多 cytokines 的分泌物。我们观察到 ATF4 被激活并且 translocates 到经由 TLR4-MyD88-dependent 小径跟随 lipopolysaccharide (LPS ) 刺激的原子核。另外, cytokine 数组试金证明某关键煽动性的 cytokines 例如 IL-6, IL-8 和 RANTES,被 ATF4 断然调整。我们也证明 c6 月直接绑在 ATF4,从而支持煽动性的 cytokines 的分泌物。一起拿,这些结果显示 ATF4 在被触发 TLR4 的 cytokine 充当一个积极管理者生产。 | Chunyan Zhang Nan Bai Antao Chang Zhuhong Zhang Jing Yin Wenzhi Shen Yaping Tian RongXiang Chenghu Liu | 2013 | Cellular & Molecular Immunology2013，10，1： | 5 |
| 3 | Adaptive sampling immune algorithm solving joint chance-constrained programming显示文摘This work investigates one immune optimization algorithm in uncertain environments, solving linear or nonlinear joint chance-constrained programming with a general distribution of the random vector. In this algorithm, an a priori lower bound estimate is developed to deal with one joint chance constraint, while the scheme of adaptive sampling is designed to make empirically better antibodies in the current population acquire larger sample sizes in terms of our sample-allocation rule. Relying upon several simplified immune metaphors in the immune system, we design two immune operators of dynamic proliferation and adaptive mutation. The first picks up those diverse antibodies to achieve proliferation according to a dynamical suppression radius index, which can ensure empirically potential antibodies more clones, and reduce noisy influence to the optimized quality, and the second is a module of genetic diversity, which exploits those valuable regions and finds those diverse and excellent antibodies. Theoretically, the proposed approach is demonstrated to be convergent. Experimentally, the statistical results show that the approach can obtain satisfactory performances including the optimized quality, noisy suppression and efficiency. | Zhuhong ZHANG Lei WANG Min LIAO | 2013 | 控制理论与应用(英文版)2013，11，2： | 4 |
| 4 | Flotation bubble seed image filling algorithm based on boundary point features显示文摘Bubble seed image filling is an important prerequisite for the image segmentation of flotation bubble that can be used to improve flotation automatic control. These common image filling algorithms in dealing with complex bubble image exists under-filling and over-filling problems. A new filling algorithm based on boundary point feature and scan lines (PFSL) is proposed in the paper. The filling algorithm describes these boundary points of image objects by means of chain codes. The features of each boundary point, including convex points, concave points, left points and right points, are defined by the point's entrancing chain code and leaving chain code. The algorithm firstly finds out all double-matched boundary points based on the features of boundary points, and fill image objects by these double-matched boundary points on scan lines. Experimental results of bubble seed image filling show that under-filling and over-filling problem can be eliminated by the proposed algorithm. | ZhuHong Zhang Guoying Liu Guanzhou Sun Qi | 2012 | International Journal of Mining Science and Technology2012，22，3： | 3 |
| 5 | Preventive effect of chrysin on experimental autoimmune uveitis triggered by injection of human IRBP peptide 1-20 in mice显示文摘Uveitis is a common cause of blindness worldwide.Experimental autoimmune uveitis(EAU)is an animal model of noninfectious uveitis.Chrysin(5,7-dihydroxyflavone)is a member of the flavonoid family and has anti-inflammatory effects.We immunized C57BL/6J mice with human interphotoreceptor retinoid-binding protein peptide 1–20 to induce EAU.Chrysin was administered intragastrically at 25 mg/kg daily to the chrysin-treated mice from 3 days before immunization to 21 days after immunization.Vehicle was administered to the mice in the control group according to the same protocol.Lower clinical and histopathological scores,increased integrity of the blood–retinal barrier(BRB)and higher expression of tight junction proteins were observed in the chrysin-treated mice.Chrysin significantly decreased the proportions of Th1,Th17 and CD4^(+)CD3^(+)CD62L^(+)Th0 cells,and increased the proportion of Treg cells.Both macrophage infiltration and the expression of inducible nitric oxide synthase in the retina were efficiently inhibited by chrysin treatment.In chrysin-treated mice,the expression of interferon-γ,interleukin(IL)-17A,IL-6,IL-1βand tumor necrosis factor-αwas reduced in the retina,whereas higher levels of transforming growth factor-βwere detected.Furthermore,NF-κBp65 was downregulated after chrysin treatment.In conclusion,as an anti-inflammatory molecule,chrysin exerts a preventive effect on EAU by modulating the balance among helper T-cell subsets and suppressing ocular inflammation,thereby maintaining the integrity of the BRB. | Xiangda Meng Sijie Fang Zhuhong Zhang Yang Wang Caiyun You Jingkai Zhang Hua Yan | 2017 | Cellular & Molecular Immunology2017，14，8： | 3 |
| 6 | Laser mass spectrometry for high sensitive and multi-component analysis of exhaust gas from vehicles显示文摘Laser mass spectrometry is a newly developed method for pollutant detection. It combines resonance-enhanced multiphoton ionization (REMPI) and time-of-flight mass spectro- metry (TOF-MS). It may detect pollutants with high sensitivity, high selectivity and in a multi-component way. In this note, laser mass spectrometry was used to detect the pollutants in exhaust gases from vehicles. With one-color REMPI (at 266 nm), several aromatic hydrocarbons, including benzene, toluene, xylene, C3-benzene, etc., were detected. These substances were selectively ionized by (1+1) REMPI and their mass resolution was detected by a TOF mass spectrometer. And a quantitative analysis was achieved. | Liandi Zhang Jie Wei Haiyang Zheng Ziyao Li Zhuhong Xia Xuejun Gu Bin Zhang | 2001 | Chinese Science Bulletin2001，46，1： | 2 |
| 7 | Bioaccessibility and health risk of arsenic and heavy metals (Cd, Co, Cr, Cu, Ni, Pb, Zn and Mn) in TSP and PM2.5 in Nanjing, China显示文摘 | Xin Hu Yun Zhang Zhuhong Ding Tijian Wang Hongzhen Lian Yuanyuan Sun Jichun Wu | 2012 | Atmospheric Environment2012，，： | 2 |
| 8 | Construction of Air Quality Evaluation System Based on FCM Algorithm and BP Neural Network显示文摘In order to solve the limitations of existing air quality evaluation system,a new air quality evaluation system was established based on FCM,the BP neural network,with the aim to provide scientific bases for the targeted and efficient control of air pollution,formulation of prevention and control strategy,and improvement of living environment. Based on the existing data of 6 air quality indices,the air quality data were reclassified by using FCM algorithm,obtaining the clustering center,which minimized the cost function of non-similar index. Then,the reclassified 6 classes of data were proceeded with BP neural network training and simulation,so as to achieve the purpose of identification,thereby forming a new air quality evaluation system. | Mingyuan WANG Zhuhong YUAN Xueyuan ZHANG Dongdong ZHENG Degang JI | 2018 | Agricultural Biotechnology2018，7，5： | 2 |
| 9 | Boundedness for Commutators of Calder o′n-Zygmund Operator on Morrey Spaces with Variable Exponent显示文摘Our aim in the present paper is to prove the boundedness of commutators on Morrey spaces with variable exponent. In order to obtain the result, we clarify a relation between variable exponent and BMO norms. | Zhuhong Xuan Lisheng Shu | 2013 | Analysis in Theory and Applications2013，29，2： | 2 |
| 10 | Multiobjective optimization immune algorithm in dynamic environments and its application to greenhouse control显示文摘 | Zhang Zhuhong | 2008 | Applied Soft Computing2008，8，2： | 1 |
| 11 | Enhanced photo catalytic activity in anatase/TiOffB) core-shell nanofiber 显示文摘 | Li Wei Liu Chang Zhou Yaxin Bai Yang Feng Xin Yang Zhuhong Lu Linghong Lu Xiaohua Chan Kwong-Yu | 2008 | Journal of Physical Chemistry C2008，112，20： | 1 |
| 12 | A shortcut for evaluating activities of TiO2 facets: water dissociative chemisorption on TiO2-B (100) and (001) 显示文摘 | Liu Weijia Wang Jianguo Li Wei Guo Xiaojing Lu Linghong Lu Xiaohua Feng Xin Liu Chang Yang Zhuhong | 2010 | Journal of Physical Chemistry C2010，12，31： | 1 |
| 13 | Lead contamination and transfer in urban environmental compartments analyzed by lead levels and isotopic compositions显示文摘 | Xin Hu Yuanyuan Sun Zhuhong Ding Yun Zhang Jichun Wu Hongzhen Lian Tijian Wang | 2014 | Environmental Pollution2014，，： | 1 |
| 14 | Maturation sequence of Tertiary crude oils in the Qaidam Basin and its significance in petroleum resource assessment显示文摘 | Huang Difan Li Jinchao Zhang Dajiang Huang Xiaoming Zhou Zhuhong | 1991 | J Southeast Asian Earth Sci1991，5，14： | 1 |
| 15 | Synthesisandpropertystudyofpolythiophene/carbon nanotubecomposites显示文摘 | GuoHongfan ZhuHong LinHaiyan etal | 2007 | JournalofFunctionalMaterials2007，38，9： | 1 |
| 16 | Preparation and characterization of mesoporous MoO3/TiO2 composite with high surface area by self-supporting and ammonia method 显示文摘 | Li Licheng Wang Yanfang Shi Kangzhong Chen Shanshan Yang Zhuhong Lu Xiaohua | 2012 | Catalysis Letters2012，142，4： | 1 |
| 17 | Low-temperature CO oxidation of gold catalysts loaded on mesoporous TiO2 whisker derived from potassium dititanate 显示文摘 | Zhu Yinhua Li Wei Zhou Yaxin Lu Xiaohua Feng Xin Yang Zhuhong | 2009 | Catalysis Letters2009，127，34： | 1 |
| 18 | Magnetic properties and martensitic transformation in quaternary heusler alloy of NiMnFeGa显示文摘 | Liu Zhuhong Zhang Ming Wang Wenquan | 2002 | J Appl Phys2002，92，9： | 1 |
| 19 | Multiobjective Optimization Immune Algorithm in Dynamic Environments and Its Application to Greenhouse Control 显示文摘 | Zhuhong Zhang | 2008 | Applied Soft Computing 8 (S 11568-4946)2008，，： | 1 |
| 20 | Stable, small, and water-soluble Cu-doped ZnS quantum dots pre- pared via femtosecond laser ablation 显示文摘 | Zheng Jinju Zheng Zhuhong Gong Weiwei | 2008 | Chemical Physics Letters2008，465，46： | 1 |
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