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| 1 | The State-of-the-Art Review on Applications of Intrusive Sensing,Image Processing Techniques,and Machine Learning Methods in Pavement Monitoring and Analysis显示文摘In modern transportation,pavement is one of the most important civil infrastructures for the movement of vehicles and pedestrians.Pavement service quality and service life are of great importance for civil engineers as they directly affect the regular service for the users.Therefore,monitoring the health status of pavement before irreversible damage occurs is essential for timely maintenance,which in turn ensures public transportation safety.Many pavement damages can be detected and analyzed by monitoring the structure dynamic responses and evaluating road surface conditions.Advanced technologies can be employed for the collection and analysis of such data,including various intrusive sensing techniques,image processing techniques,and machine learning methods.This review summarizes the state-ofthe-art of these three technologies in pavement engineering in recent years and suggests possible developments for future pavement monitoring and analysis based on these approaches. | Yue Hou Qiuhan Li Chen Zhang Guoyang Lu Zhoujing Ye Yihan Chen Linbing Wang Dandan Cao | 2021 | Engineering2021，7，6： | 3 |
| 2 | Proliferation inhibition and apoptosis promotion by dual silencing of VEGF and Survivin in human osteosarcoma显示文摘Simultaneous silencing of multiple upregulated genes is an attractive and viable treatment strat-egy for many incurable diseases including cancer.Herein we used a dual gene-targeted siRNA conjugate composed of VEGF and Survivin siRNA sequences in the same backbone to inhibit proliferation and angiogenesis in two human osteosarcoma cell lines.We synthesized siRNA sequences targeting the VEGF and Survivin genes individually (VEGF siRNA and Survivin siRNA) or simultaneously (one-chain-double-target siRNA:dual siRNA).VEGF and Survivin mRNA and protein expression levels in human osteosarcoma MG-63 and Saos-2 cells were detected by qRT- PCR and western blot analysis.VEGF and Survivin protein location and expression were evaluated by immunohistochemistry and immunofluorescence staining.MG-63 and Saos-2 cell migration,proliferation,apoptosis,and angiogenesis were detected by scratch test,MTT assay,flow cytometry,and capillary tube assay respectively.The dual siRNA induced similar downregulation of VEGF and Survivin mRNA and protein levels,compared with VEGF siRNA or Survivin siRNA alone.The dual siRNA caused greater suppression of MG-63 and Saos-2 cell migration,proliferation and angiogenesis,and promoted more cell apoptosis than VEGF siRNA or Survivin siRNA alone,suggesting that the effects of the dual siRNA on inhibiting cell proliferation,migration,and angiogenesis and promoting apoptosis were superior to those of the single-target siRNAs.Simultaneous silencing of VEGF and Survivin using the dual siRNA may be an advantageous alternative for the development of therapeutic strategies against human osteosarcoma. | Junquan Gu Zhoujing Ji Dong Li Qirong Dong | 2019 | Acta Biochimica et Biophysica Sinica2019，51，1： | 2 |
| 3 | Chemotherapeutic nanomaterials in tumor boundary delineation:Prospects for effective tumor treatment显示文摘Accurately delineating tumor boundaries is key to predicting survival rates of cancer patients and assessing response of tumor microenvironment to various therapeutic techniques such as chemotherapy and radiotherapy.This review discusses various strategies that have been deployed to accurately delineate tumor boundaries with particular emphasis on the potential of chemotherapeutic nanomaterials in tumor boundary delineation.It also compiles the types of tumors that have been successfully delineated by currently available strategies.Finally,the challenges that still abound in accurate tumor boundary delineation are presented alongside possible perspective strategies to either ameliorate or solve the problems.It is expected that the information communicated herein will form the first compendious baseline information on tumor boundary delineation with chemotherapeutic nanomaterials and provide useful insights into future possible paths to advancing current available tumor boundary delineation approaches to achieve efficacious tumor therapy. | Ozioma Udochukwu Akakuru Zhoujing Zhang M.Zubair Iqbal Chengjie Zhu Yewei Zhang Aiguo Wu | 2022 | Acta Pharmaceutica Sinica B2022，12，6： | 2 |
| 4 | A distributed pavement monitoring system based on Internet of Things显示文摘Pavement is an important part of transportation infrastructure.In order to maintain pavement before the damage and improve the service quality,it is necessary to develop an intelligent and durable pavement information monitoring system.However,the pavement dynamic response monitoring is highly costly,easily obsolete and statistically redundant.The emergence of the Internet of Things(IoT)technology promises to change that.In this paper,an architecture of a distributed road IoT monitoring system is proposed,which has an acquisition layer,a preprocessing layer,a processing layer,an interaction layer,an energy layer and a network layer.Then,a prototype wireless pavement vibration monitoring system based on the IoT is developed,which consists of a number of wireless sensing nodes,a gateway,a remote server and a browser.Finally,data preprocessing,wireless communication,time synchronization,data processing and visualization,which represent the key to an effective system,are tested and discussed.The prototype wireless pavement vibration monitoring system provides a viable scheme for upgrading the IoT system and its application in the road infrastructures.In the future,any smart road will have an IoT wireless monitoring system to monitor the traffic,environment,and pavement information,which help enable traffic guidance,signal control,danger warning,scientific maintenance decision-making. | Zhoujing Ye Ya Wei Jianfeng Li Guannan Yan Linbing Wang | 2022 | Journal of Traffic and Transportation Engineering(English Edition)2022，9，2： | 2 |
| 5 | Soil Manganese and Iron Released due to Calcium Salts:Bioavailability to Pepper (Capsicum frutescens L.)显示文摘Releases of manganese and iron ions from an albic soil (Albic-Udic Luvisol), a yellow-red soil (Hap-Udic Ferrisol) and a yellow-brown soil (Arp-Udic Luvisol) induced by calcium salt addition and their bioavailability to pepper (Capsicum frutescens L.) were studied in a pot experiment. Addition of Ca(NO3)2 decreased soil pH and increased both exchangeable and DTPA (diethylenetriamine pentaacetic acid)-extractable Mn and Fe in soils. Meanwhile, total Mn accumulation in the shoots of Capsicum frutescens L. on the salt-treated soils increased significantly (P < 0.01) compared with the control, suggesting that salt addition to soil induced Mn toxicity in Capsicum frutescens L. Although exchangeable and DTPA-extractable Fe increased also in the salt-treated soils, Fe uptake by the shoots of Capsicum frutescens L. decreased. The effect of added salts in soils on dry matter weight of pepper varied with the soil characteristics, showing different buffer capacities of the soils for salt toxicity in an order of yellow-brown soil > albic soil > yellow-red soil. Fe/Mn ratio in shoots of Capsicum frutescens L. decreased with increasing salt addition for all the soils, which was ascribed to the antagonistic effect of Mn on Fe accumulation. The ratio of Fe/Mn in the tissue was a better indicator of the appearance of Mn toxicity symptoms than Mn concentration alone. | SIYou-Bin ZHOUJing ZHOUDong-Mei CHENHuai-Man | 2004 | Pedosphere2004，14，1： | 2 |
| 6 | CD14(hi)CD16+ monocytes phagocytose antibody-opsonised Plasmodium falciparum infected erythrocytes more efficiently than other monocyte subsets,and require CD16 and complement to do so显示文摘 | ZhouJ FengG BeesonJ | 2015 | BMC Med2015，13，： | 1 |
| 7 | Geochronology and geochemistry of Neoproterozoic mafic rocks from western Human,SouthChina:implications for petrogenesis and post-orogenic extension显示文摘 | Wang x L ZhouJ c Qiu J s | 2008 | Geological Magazine2008，145，2： | 1 |
| 8 | Prognostics for state of health estimation of lithium-ion batteries based on combination Gaussian process functional regression显示文摘 | LIU D PANGJ ZHOUJ | 2013 | Microelectronics Reliability2013，53，6： | 1 |
| 9 | Reference Values for continuous glucose monitoring in Chinese subjects 显示文摘 | ZhouJ LiH RuanXW etM | 2009 | Diabetes Care2009，32，7： | 1 |
| 10 | Synthesis of aluminum borate nanorods by a low-heating-temperature solid-state precursor method显示文摘 | ZhouJ SU D G LuoJ M et at | 2009 | Materi Res Bull2009，44，1： | 1 |
| 11 | CC-MS Study on volatile oilcomposition of Glycosmis citrfolia ( Willdl ) Lindl显示文摘 | ZhouB(周波) ZhouJ(周静) | 2004 | 中药材2004，27，： | 1 |
| 12 | HIF-1 and p53:communication of transcription factors under hypoxia显示文摘 | SCHMIDT ZHOUJ BRUNEB | 2004 | J Cell Mol Med2004，8，4： | 1 |
| 13 | Fate and assessment of persistent organic pollutants in water and sediment from Minjiang River Estuary, Southeast China 显示文摘 | Zhang Z L Hong H S ZhouJ L | 2003 | Chemosphere2003，52，9： | 1 |
| 14 | Cyclophilin A upregulates MMP-9 expression and adhesion of monocytes/macrophages via CD147 signalling pathway in rheumatoid arthritis显示文摘 | YangY Lu N ZhouJ | 2008 | Rheumatology (Oxford)2008，47，9： | 1 |
| 15 | The anticancer efficacy of paclitaxel liposomes modified with mitochondrial targeting conjugate in resistant lung cancer显示文摘 | ZhouJ Zhao W Y Ma X | 2013 | Biomaterials2013，34，14： | 1 |
| 16 | miR9and NFATc3regulatemyocardinincardiachypertrophy显示文摘 | WangK LongB ZhouJ etal | 2010 | JBiolChem2010，285，11： | 1 |
| 17 | General design of multiway multisection power dividers by interconnecting two-way dividers 显示文摘 | ZHOUJ F MORRIS K A LANCASTER M J | 2007 | IEEE Transactions on Microwave Theory and Technicals2007，55，10： | 1 |
| 18 | Aprevalenceinvestigationofblindnessandlowvisionin2008amongadultsaged60yearsorabovein2villagesofNantong显示文摘 | ZhouJ YuanY ZhangX GuanHJ | 2012 | ZhonghuaYankeZazhi2012，48，10： | 1 |
| 19 | Altered expression of cellular membrane molecules of HLA-DR, HLA-G and CD99 in cervical intraepithelial neoplasias and invasive squamous cell carcinoma 显示文摘 | ZhouJ H YeF Chen H Z Zhou C Y LuWG XieX | 2006 | Life Sci2006，78，： | 1 |
| 20 | Integrated reeonfiguration and age-based preventive maintenance decision making 显示文摘 | ZhouJ Djurdjanovic D Julie I | 2007 | IIE Transactions2007，39，12： | 1 |
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