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| 1 | New eolian red clay sequence on the western Chinese Loess Plateau linked to onset of Asian desertification about 25 Ma ago显示文摘The expansion of inland Asia deserts has considerably influenced the environmental, social and economic activities in Asia. Aridification of inland Asia, especially timing of the initiation of Asian desertification, is a contentious topic in paleoclimatology. Late Cenozoic eolian loess-red clay sequences on the Chinese Loess Plateau, which possess abundant paleoclimatic and paleo-environmental information, can be regarded as an indicator of inland Asia desertification. Here we present a detailed magnetostratigraphic investigation of a new red clay sequence about 654 m in Zhuanglang located at the western Chinese Loess Plateau. Sedimentological, geochemical, mineralogical, and quartz morphological lines of evidence show that the red clay is of eolian origin. Magnetostratigraphic correlations indicate that this core sequence spans from 25.6 to 4.8 Ma, and typical eolian red clay appears as early as 25 Ma. This extends the lower limit of the red clay on the Chinese Loess Plateau from the previously thought early Miocene back into the late Oligocene. This new red clay record further implies that the inland Asia desertification was initiated at least by the late Oligocene. This sequence provides a unique high-resolution geological record for understanding the inland Asia desertification process since the late Oligocene. | QIANG XiaoKe AN ZhiSheng SONG YouGui CHANG Hong SUN YouBin LIU WeiGuo AO Hong DONG JiBao FU ChaoFeng WU Feng LU FengYan CAI YanJun ZHOU WeiJian CAO JunJi XU XinWen AI Li | 2011 | Science China Earth Sciences2011，54，1： | 73 |
| 2 | Petroleum Origins and Accumulation Patterns in the Weixinan Sag in the Beibu Gulf Basin,Using Subsag B as an Example显示文摘Crude oil has been discovered in the Paleogene and Neogene units of the Weixinan Sag in the Beibu Gulf Basin.To determine the source and accumulation mode of this crude oil,12 crude oil samples and 27 source rock samples were collected and an extensive organic geochemical analysis was conducted on them.Based on the geological conditions and the analytical results,the types,origins and accumulation patterns of crude oil in the study area were elucidated.Except for a shallowly-buried and biodegraded crude oil deposit in Neogene rocks,the crude oil samples in the study area were normal.All of the crude oils were derived from lacustrine source rocks.According to biomarker compositions,the crude oils could be divided into two families,A and B,distinctions that were reinforced by differences in carbon isotope composition and spatial distribution.Oil-source correlation analysis based on biomarkers revealed that Family A oils were derived from the mature oil shale at the bottom of the second member of the Liushagang Formation,while the Family B oils formed in the mature shale of the Liushagang Formation.The Family A oils,generated by oil shale,mainly migrated laterally along sand bodies and were then redistributed in adjacent reservoirs above and below the oil shale layer,as well as in shallow layers at high structural positions,occupying a wide distribution range.The Family B oils were generated by other shale units before migrating vertically along faults to form reservoirs nearby,resulting in a narrow distribution range. | GAO Gang XU Xinde QU Tong GAN Jun DANG Wenlong ZHOU Xiaoxiao LIU Fengyan | 2020 | Acta Geologica Sinica(English Edition)2020，94，5： | 3 |
| 3 | HSO_3-functionalized Br nsted acidic ionic liquids promote esterification of aromatic acid显示文摘Esterification of aromatic acid can be promoted via HSO3-functionalized Br nsted acidic ionic liquids (ILs). Under the optimum conditions, using 1-(3-sulfonic acid) propyl-3-methylimidazolium hydrogen sulfate ([MimC3SO3H][HSO4]) and 1-(4-sulfonic acid) butyl-3-methylimidazolium hydrogen sulfate ([MimC 4 SO 3 H][HSO4 ]) as dual solvent-catalysts, the conversion of esterification of aromatic acid was determined to be more than 90%, indicating that HSO3-functionalized ILs show much better catalytic ability than those of non-functionalized ionic liquids. The separation of desired product was easily performed by extraction with diethyl ether and these HSO3-functionalized ILs could be reused 7 times after vacuum drying. Our data represent an environmentally friendly method for the preparation of aromatic esters. | ZHOU FengYan XIN BingWei HAO JingCheng | 2013 | Chinese Science Bulletin2013，58，26： | 2 |
| 4 | Resistance to ACCase-inhibiting herbicides in an Asia minor bluegrass ( Polypogon fugax ) population in China显示文摘 | Wei Tang Fengyan Zhou Jie Chen Xiaogang Zhou | 2013 | Pesticide Biochemistry and Physiology2013，，： | 1 |
| 5 | GLTSCR1 coordinates alternative splicing and transcription elongation of ZO1 to regulate colorectal cancer progression显示文摘Alternative splicing(AS)and transcription elongation are vital biological processes,and their dysregulation causes multiple diseases,including tumors.However,the coregulatory mechanism of AS and transcription elongation in tumors remains unclear.This study demonstrates a novel AS pattern of tight junction protein 1(ZO1)regulated by the RNA polymerase II elongation rate in colorectal cancer(CRC).Glioma tumor suppressor candidate region gene 1(GLTSCR1)decreases the transcription elongation rate of ZO1 to provide a time window for binding of the splicing factor HuR to the specific motif in intron 22 of ZO1 and spliceosome recognition of the weak 3 and 5 splice sites in exon 23 to promote exon 23 inclusion.Since exon 23 inclusion in ZO1 suppresses migration and invasion of CRC cells,our findings suggest a novel potential therapeutic target for CRC. | Fengyan Han Beibei Yang Mingyue Zhou Qiong Huang Minglang Mai Zhaohui Huang Maode Lai Enping Xu Honghe Zhang | 2022 | Journal of Molecular Cell Biology2022，14，2： | 1 |
| 6 | Synthesis, characterization and hydrotreating performance of supported tungsten phosphide catalysts显示文摘Supported tungsten phosphide catalysts were prepared by temperature-programmed reduction of their precursors(supported phospho-tungstate catalysts)in H2 and characterized by X-ray diffraction(XRD),BET,temperature-programmed desorption of ammonia(NH3-TPD)and X-ray photoelectron spectroscopy(XPS).The reduction-phosphiding processes of the precursors were investigated by thermogravimetry and differential thermal analysis(TG-DTA)and the suitable phosphiding temperatures were defined.The hydrodesulfurization(HDS)and hydrodenitrogenation(HDN)activities of the catalysts were tested by using thiophene,pyridine,dibenzothiophene,carbazole and diesel oil as the feedstock.The TiO2,c-Al_(2)O_(3) supports and the Ni,Co promoters could remarkably increase and stabilize active W species on the catalyst surface.A suitable amount of Ni(3%–5%),Co(5%–7%)and V(1%–3%)could increase dispersivity of the W species and the BET surface area of the WP/c-Al_(2)O_(3) catalyst.The WP/c-Al_(2)O_(3) catalyst possesses much higher thiophene HDS and carbazole HDN activities and the WP/TiO2 catalyst has much higher dibenzothiophene(DBT)HDS and pyridine HDN activities.The Ni,Co and V can obviously promote the HDS activity and inhibit the HDN activity of the WP/c-Al_(2)O_(3) catalyst.The G-Ni5 catalyst possesses a much higher diesel oil HDS activity than the sulphided industrial NiW/c-Al_(2)O_(3) catalyst.In general,a support or promoter in the WP/c-Al_(2)O_(3) catalyst which can increase the amount and dispersivity of the active W species can promote its HDS and HDN activities. | Guida SUN Cuiqing LI Zhijun ZHOU Fengyan LI | 2008 | Frontiers of Chemical Science and Engineering2008，2，2： | 0 |
| 7 | TRAF3 activates STING-mediated suppression of EV-A71 and target of viral evasion显示文摘Innate immunity represents one of the main host responses to viral infection.1,2,3 STING(Stimulator of interferon genes),a crucial immune adapter functioning in host cells,mediates cGAS(Cyclic GMP-AMP Synthase)sensing of exogenous and endogenous DNA fragments and generates innate immune responses.4 Whether STING activation was involved in infection and replication of enterovirus remains largely unknown.In the present study,we discovered that human enterovirus A71(EV-A71)infection triggered STING activation in a cGAS dependent manner.EV-A71 infection caused mitochondrial damage and the discharge of mitochondrial DNA into the cytosol of infected cells.However,during EV-A71 infection,cGAS-STING activation was attenuated.EV-A71 ^(pro)teins were screened and the viral ^(pro)tease 2A^(pro) had the greatest capacity to inhibit cGAS-STING activation.We identified TRAF3 as an important factor during STING activation and as a target of 2A^(pro).Supplement of TRAF3 rescued cGAS-STING activation suppression by 2A^(pro).TRAF3 supported STING activation mediated TBK1 phosphorylation.Moreover,we found that 2A^(pro) ^(pro)tease activity was essential for inhibiting STING activation.Furthermore,EV-D68 and CV-A16 infection also triggered STING activation.The viral ^(pro)tease 2A^(pro) from EV-D68 and CV-A16 also had the ability to inhibit STING activation.As STING activation prior to EV-A71 infection generated cellular resistance to EV-A71 replication,blocking EV-A71-mediated STING suppression represents a new anti-viral target. | Wenwen Zheng Zhenbang Zhou Yajuan Rui Runxin Ye Fengyan Xia Fei Guo Xiaoman Liu Jiaming Su Meng Lou Xiao-Fang Yu | 2023 | Signal Transduction and Targeted Therapy2023，8，3： | 0 |
| 8 | ALIKHANOV LINEARIZED GALERKIN FINITE ELEMENT METHODS FOR NONLINEAR TIME-FRACTIONAL SCHRODINGER EQUATIONS显示文摘We present Alikhanov linearized Galerkin methods for solving the nonlinear time fractional Schrödinger equations.Unconditionally optimal estimates of the fully-discrete scheme are obtained by using the fractional time-spatial splitting argument.The convergence results indicate that the error estimates hold without any spatial-temporal stepsize restrictions.Numerical experiments are done to verify the theoretical results. | Hongyu Qin Fengyan Wu Boya Zhou | 2023 | Journal of Computational Mathematics2023，41，6： | 0 |
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