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| 1 | Genome of Wild Mandarin and Domestication History of Mandarin显示文摘官员(柠檬 reticulata ) 是世界范围的最重要的柠檬庄稼之一。它的驯服被相信发生在华南,它是四几千年的官员耕作的中心之一。我们在 Nanling 区域附近收集了官员的自然野人口并且在附近栽培了 landraces。我们发现柠檬性的酸水平戏剧性地在栽培官员被减少。理解 ? 官员驯服的基因基础,我们 de novo 装配了野官员的一个草稿染色体并且分析了一套 104 个柠檬染色体。我们发现 Mangshan 官员是一种原始类型并且二个独立驯服事件发生了,分别地导致在北方和南方 Nanling 山的二组栽培官员(MD1 和 MD2 ) 。二个瓶颈和有效人口尺寸的二扩大为栽培官员的 MD1 组被识别。然而,在 MD2 组织 ? 在人口尺寸有长、连续的减少。MD1 和 MD2 官员从栽培 pummelo 种类显示出种间的基因渗入的不同模式。我们在官员的驯服期间在选择下面可能在基因在柠檬酸盐内容的规定包含了的 aconitate hydratase (ACO ) 识别了高分叉的一个区域,它是。这研究为现存野官员人口的地理起源提供具体基因证据并且使驯服和官员的进化历史清楚些。 | Lun Wang Fa He Yue Huang Jiaxian He Shuizhi Yang Jiwu Zeng Chongling Deng Xiaolin Jiang Yiwen Fang Shaohua Wen Rangwei Xu Huiwen Yu Xiaoming Yang Guangyan Zhong Chuanwu Chen Xiang Yan Changfu Zhou Hongyan Zhang Zongzhou Xie Robert M. Larkin Xiuxin Deng Qiang Xu | 2018 | Molecular Plant2018，11，8： | 14 |
| 2 | Feedback Regulation of FLC by FLOWERING LOCUS T (FT) and FD through a 5’ FLC Promoter Region in Arabidopsis显示文摘Dear Editor, Recently, it was reported that the florigenic FT protein bound to a 3’ region of the potent floral repressor FLC (FLOWERING LOCUS C) to activate the expression of long noncoding antisense RNAs known as COOLAIR and consequently repress FLC expression to control flowering time and seed dormancy in Arabidopsis (Chen and Penfield, 2018). Here, we show that FT represses FLC expression through a 5' promoter region, but not COOLAIR. | Xiao Luo Tao Chen Xiaolin Zeng Dingwei He Yuehui He | 2019 | Molecular Plant2019，12，3： | 10 |
| 3 | Results and Analyses of BDS Precise Orbit Determination with the Enhancement of Fengyun-3C显示文摘Global navigation satellite system occultation sounder (GNOS) Fengyun-3C was launched successfully on September 23, 2013, which carried GPS/BDS receiver for the first time. This provides the convenience to study the enhancement results of low earth orbiter satellite (LEO) to BDS precise orbit determination (POD). First the data characteristic and code observation noise of GNOS are analyzed. Then the enhancement experiments in the case of global and regional ground observation stations layout are processed with four POD schemes: BDS single system, GPS/BDS double system, BDS single system with GNOS observations, GPS/BDS double system with GNOS observations. The precision of BDS orbits and clocks are compared via overlapping arcs. Results show that in the case of global station layout the along directional precision of GEO satellite has the biggest improvement, with the improvement percentage 60%. Then the precision of cross direction and the along direction of remaining satellites shows the second biggest improvement. The orbit precision of BDS-only POD in part of observation arcs some satellite even suffers a slight decline. The root mean square (RMS) of overlapping clock difference of visible arcs in GPS/BDS POD experiments improves by 0.1 ns level. As to the experiments of regional station layout with 7 ground stations, the orbit and clock overlapping precision and orbit predicting precision are analyzed. Results show that the predicting precision of BDS GEO satellites in the along direction improves by 85%. The remaining also has a substantial improvement, with the average percentage 21.7%. RMS of overlapping clock difference of visible arcs improves by 0.5 ns level. | Tian ZENG Lifen SUI Xiaolin JIA Guofeng JI Qinghua ZHANG | 2019 | Journal of Geodesy and Geoinformation Science2019，2，3： | 9 |
| 4 | The synergistic effect of resveratrol in combination with cisplatin on apoptosis via modulating autophagy in A549 cells显示文摘几研究证明了有自然产品和化疗代理人的联合治疗能改进化疗代理人的 sensitivityand cytotoxicity。Resveratrol,一个自然产品,包括 antitumor andantiviral 活动,以及脉管的保护的效果有许多生物效果。这研究的目的是与 cisplatin 和涉及 A549 房间的潜在的 anticancer 机制在联合调查 resveratrol 的 synergistic anticancereffect。从数 Kit-8 和 isobolographic 分析的房间的 resultsobtained 表明了 resveratrol 和 cisplatin resultedin synergistic 的那联合在 A549 房间的细胞毒素的效果。从染色的 Hoechst 的结果,流动 cytometry 和西方的污点分析 suggestedthat resveratrol 提高了调停 cisplatin 的 apoptosis。同时, LC3-II 和 P62 层次和在有 cisplatin 的联合的 resveratrol 触发了的 autophagosomesuggested 的形成的变化 autophagy。更重要地,由 3-methyladeninemarkedly 禁止 autophagy 稀释了 resveratrol 和 cisplatin 的联合在 A549 房间引起的 apoptosis。一起拿,我们的 studyprovides resveratrol synergistically 与 cisplatin 相结合的第一条证据在 A549 房间经由 modulating autophagiccell 死亡导致 apoptosis。这些调查结果也帮助我们在肺癌症与 chemotherapyagents 在联合理解自然产品的角色。 | Song Hu Xiaolin Li Rongrong Xu Lingyun Ye Hui Kong Xiaoning Zeng Hong Wang Weiping Xie | 2016 | Acta Biochimica et Biophysica Sinica2016，48，6： | 9 |
| 5 | The relations among the three kinds of conditional risk measures显示文摘Let(Ω,E,P)be a probability space,F a sub-σ-algebra of E,Lp(E)(1 p+∞)the classical function space and Lp F(E)the L0(F)-module generated by Lp(E),which can be made into a random normed module in a natural way.Up to the present time,there are three kinds of conditional risk measures,whose model spaces are L∞(E),Lp(E)(1 p<+∞)and Lp F(E)(1 p+∞)respectively,and a conditional convex dual representation theorem has been established for each kind.The purpose of this paper is to study the relations among the three kinds of conditional risk measures together with their representation theorems.We first establish the relation between Lp(E)and Lp F(E),namely Lp F(E)=Hcc(Lp(E)),which shows that Lp F(E)is exactly the countable concatenation hull of Lp(E).Based on the precise relation,we then prove that every L0(F)-convex Lp(E)-conditional risk measure(1 p+∞)can be uniquely extended to an L0(F)-convex Lp F(E)-conditional risk measure and that the dual representation theorem of the former can also be regarded as a special case of that of the latter,which shows that the study of Lp-conditional risk measures can be incorporated into that of Lp F(E)-conditional risk measures.In particular,in the process we find that combining the countable concatenation hull of a set and the local property of conditional risk measures is a very useful analytic skill that may considerably simplify and improve the study of L0-convex conditional risk measures. | GUO TieXin ZHAO ShiEn ZENG XiaoLin | 2014 | Science China Mathematics2014，57，8： | 6 |
| 6 | CeO_2/CuO catalysts using different template agent for preferential CO oxidation in H_2-rich stream显示文摘The CeO_2/CuO catalysts using different template agent(F68 L64, F127 and P123) were synthesized by the simple template and impregnation method. They were characterized by FESEM, XRD, N2 physisorption and H2-TPR techniques. It is found that the CeO_2/CuO catalysts are double pore distribution, and CeO_2 can enter into the gap of CuO supports and form the contact interface of copper and cerium. Among the asprepared catalysts, the CeO_2/CuO-F127 catalyst displays better activity at lower temperature and the CeO_2/CuO-P123 catalyst presents higher activity at higher temperature. The CeO_2/CuO-P123 catalyst has the smallest crystallite sizes of CuO and CeO_2 as well as the largest size of cubes, which may improve the interaction of copper and cerium and enhance the performance of CO oxidation. | Xiaolin Yan Aiai Zhang Meiyi Gao Shanghong Zeng | 2017 | Journal of Rare Earths2017，35，12： | 5 |
| 7 | Similar Ability of FbaA with M Protein to Elicit Protective Immunity Against Group A Streptococcus Challenge in Mice显示文摘Group A streptococcus(GAS),an important human pathogen,can cause various kinds of infections including superficial infections and potentially lethal infections,and the search for an effective vaccine to prevent GAS infections has been ongoing for many years. This paper compares the immunogenicity and immunoprotection of FbaA(an Fn-binding protein expressed on the surface of GAS) with that of M protein,the best immunogen of GAS. Assay for immune response showed that FbaA,similar to M protein,could induce protein-specific high IgG titer in BALB/c mice. Furthermore,following GAS challenge,the mice immunized with FbaA showed the same protective rate as those with M protein. These results indicate that FbaA is similar in ability to M protein in inducing protective immunity against GAS challenge in mice. | Cuiqing Ma Caihong Li Xiurong Wang Ruihong Zeng Xiaolin Yin Huidong Feng Lin Wei | 2009 | Cellular & Molecular Immunology2009，6，1： | 4 |
| 8 | Magnetic plasmon resonances in nanostructured topological insulators for strongly enhanced light-MoS_(2) interactions显示文摘Magnetic resonances not only play crucial roles in artificial magnetic materials but also offer a promising way for light control and interaction with matter.Recently,magnetic resonance effects have attracted special attention in plasmonic systems for overcoming magnetic response saturation at high frequencies and realizing high-performance optical functionalities.As novel states of matter,topological insulators(TIs)present topologically protected conducting surfaces and insulating bulks in a broad optical range,providing new building blocks for plasmonics.However,until now,high-frequency(e.g.visible range)magnetic resonances and related applications have not been demonstrated in TI systems.Herein,we report for the first time,to our knowledge,a kind of visible range magnetic plasmon resonances(MPRs)in TI structures composed of nanofabricated Sb_(2)Te_(3) nanogrooves.The experimental results show that the MPR response can be tailored by adjusting the nanogroove height,width,and pitch,which agrees well with the simulations and theoretical calculations.Moreover,we innovatively integrated monolayer MoS_(2) onto a TI nanostructure and observed strongly reinforced light-MoS_(2) interactions induced by a significant MPR-induced electric field enhancement,remarkable compared with TI-based electric plasmon resonances(EPRs).The MoS_(2) photoluminescence can be flexibly tuned by controlling the incident light polarization.These results enrich TI optical physics and applications in highly efficient optical functionalities as well as artificial magnetic materials at high frequencies. | Hua Lu Zengji Yue Yangwu Li Yinan Zhang Mingwen Zhang Wei Zeng Xuetao Gan Dong Mao Fajun Xiao Ting Mei Weiyao Zhao Xiaolin Wang Min Gu Jianlin Zhao | 2020 | Light(Science & Applications)2020，9，1： | 3 |
| 9 | Molecular basis of CONSTANS oligomerization in FLOWERING LOCUS T activation显示文摘The transcription factor CONSTANS(CO)integrates day-length information to induce the expression of florigen FLOWERING LOCUS T(FT)in Arabidopsis.We recently reported that the C-terminal CCT domain of CO forms a complex with NUCLEAR FACTOR-YB/YC to recognize multiple cis-elements in the FT promoter,and the N-terminal tandem B-box domains form a homomultimeric assembly.However,the mechanism and biological function of CO multimerization remained unclear.Here,we report that CO takes on a head-to-tail oligomeric configuration via its B-boxes to mediate FT activation in long days.The crystal structure of B-boxesCOreveals a closely connected tandem B-box fold forming a continuous head-to-tail assembly through unique CDHH zinc fingers.Mutating the key residues involved in CO oligomerization resulted in a non-functional CO,as evidenced by the inability to rescue co mutants.By contrast,a transgene encoding a human p53-derived tetrameric peptide in place of the B-boxesCOrescued co mutant,emphasizing the essential role of BboxesCO-mediated oligomerization.Furthermore,we found that the four TGTG-bearing cis-elements in FT proximal promoter are required for FT activation in long days.Our results suggest that CO forms a multimer to bind to the four TGTG motifs in the FT promoter to mediate FT activation. | Xiaolin Zeng Xinchen Lv Rui Liu Hang He Shiqi Liang Lixian Chen Fan Zhang Liu Chen Yuehui He Jiamu Du | 2022 | Journal of Integrative Plant Biology2022，64，3： | 2 |
| 10 | Uncombined precise orbit and clock determination of GPS and BDS-3显示文摘There is increasing concern about the uncombined(UC)observation model in the field of global navigation satellite system(GNSS).Based on the global positioning system(GPS)and the third-generation BeiDou navigation satellite system(BDS-3),this study processed the UC precision orbit determination(POD)for single and dual systems.First,a UC observation model suitable for multi-GNSS POD was derived,and the ionospheric-free(IF)combination observation model was presented.Although the ambiguity parameters of UC and IF strategies were different after reparameterization,the difference could be removed when processing ambiguity resolution,and the equivalence was proved theoretically.To demonstrate the accuracy of BDS-3 orbits fully,the observation data of approximately 1 month were selected for determining the precise orbit for global positioning system(GPS)only,BDS-3 only,and GPS/BDS-3 systems based on the UC and IF models.The orbit precision of BDS-3 satellites was validated by using metrics,including comparison with precision products released by Wuhan University,orbit boundary discontinuity,and satellite laser ranging(SLR)residuals.The results show that the orbit accuracies of the IF and UC models are almost the same,the difference in orbits is approximately several millimeters,and the clock difference is within 0.01 ns.The GPS/BDS-3 combined solution shows better accuracy compared to other solutions.The average accuracies in the R and 3D directions are approximately 4 and 15 cm,and the clock standard deviation is approximately 0.2 ns compared to external orbit product.The root mean square of SLR residuals is approximately 4 cm. | Tian Zeng Lifen Sui Rengui Ruan Xiaolin Jia Laiping Feng | 2020 | Satellite Navigation2020，1，1： | 2 |
| 11 | Engineering hiPSC-CM and hiPSC-EC laden 3D nanofibrous splenic hydrogel for improving cardiac function through revascularization and remuscularization in infarcted heart显示文摘Cell therapy has been a promising strategy for cardiac repair after myocardial infarction(MI),but a poor ischemic environment and low cell delivery efficiency remain significant challenges.The spleen serves as a hematopoietic stem cell niche and secretes cardioprotective factors after MI,but it is unclear whether it could be used for human pluripotent stem cell(hiPSC)cultivation and provide a proper microenvironment for cell grafts against the ischemic environment.Herein,we developed a splenic extracellular matrix derived thermoresponsive hydrogel(SpGel).Proteomics analysis indicated that SpGel is enriched with proteins known to modulate the Wnt signaling pathway,cell-substrate adhesion,cardiac muscle contraction and oxidation-reduction processes.In vitro studies demonstrated that hiPSCs could be efficiently induced into endothelial cells(iECs)and cardiomyocytes(iCMs)with enhanced function on SpGel.The cytoprotective effect of SpGel on iECs/iCMs against oxidative stress damage was also proven.Furthermore,in vivo studies revealed that iEC/iCM-laden SpGel improved cardiac function and inhibited cardiac fibrosis of infarcted hearts by improving cell survival,revascularization and remuscularization.In conclusion,we successfully established a novel platform for the efficient generation and delivery of autologous cell grafts,which could be a promising clinical therapeutic strategy for cardiac repair and regeneration after MI. | Ge Guan Da Huo Yanzhao Li Xiaolin Zhao Yinghao Li Zhongliang Qin Dayu Sun Guanyuan Yang Mingcan Yang Ju Tan Wen Zeng Chuhong Zhu | 2021 | Bioactive Materials2021，6，12： | 2 |
| 12 | Constructing supramolecular nanostructure by hydrogen-bonding显示文摘The diquinoxalino (2.3-2′.3′-a.c) phenazine (DQP), containing 6 nitrogen atoms, was synthesized, and its adsorption and self-assembling behavior on highly oriented pyrolytic graphite (HOPG) was studied by scanning tunneling microscopy (STM) under ambient conditions. With 1,14-tetradecanedioic acid as a bridge, uniform two-dimensional arrays of 1,14-tetradecanedioic acid/DQP nanostructure were successfully fabricated. The result illustrates that it is possible to construct and control supramolecular nanostructure by intermolecular hydrogen-bonding. | LI YiBao ZENG QingDao WANG ZhiHui QI GuiCun GUAN Li FAN XiaoLin WANG Chen | 2008 | Chinese Science Bulletin2008，53，10： | 2 |
| 13 | Genetic and Epigenetic Understanding of the Seasonal Timing of Flowering显示文摘The developmental transition to flowering in many plants is timed by changing seasons,which enables plants to flower at a season that is favorable for seed production.Many plants grown at high latitudes perceive the seasonal cues of changing day length and/or winter cold(prolonged cold exposure),to regulate the expression of flowering-regulatory genes through the photoperiod pathway and/or vernalization pathway,and thus align flowering with a particular season.Recent studies in the model flowering plant Arabidopsis thaliana have revealed that diverse transcription factors engage various chromatin modifiers to regulate several key flowering-regulatory genes including FLOWERING LOCUS C(FLC)and FLOWERING LOCUS T(FT)in response to seasonal signals.Here,we summarize the current understanding of molecular and chromatin-regulatory or epigenetic mechanisms underlying the vernalization response and photoperiodic control of flowering in Arabidopsis.Moreover,the conservation and divergence of regulatory mechanisms for seasonal flowering in crops and other plants are briefly discussed. | Yuehui He Tao Chen Xiaolin Zeng | 2020 | Plant Communications2020，1，1： | 2 |
| 14 | Defining an open access resource strategy for research libraries:Part Ⅰ—The coming main streamlization of open access resources?显示文摘Open access(OA)resources are becoming a main part of scholarly information.The paper summarizes the fast growth of OA journals and OA repositories,the outstanding OA journal impact increase,the rise of mega-OA journals like PLoS ONE,the overwhelming support of research communities to open access of publicly funded research,and the quick building up of OA support structures.These forces work together to push scholarly communications toward a turning point where OA resources occupy a major and increasing share of scholarly research resources and when management of OA resources becomes a strategic,yet unfamiliar,and potentially disruptive task for research libraries.This paper is composed of two parts.The first part will focus on the development of OA resources,while the second part will analyze the challenges in management of OA resources and develop an OA resource strategy exemplified by some of NSL’s initiatives. | Xiaolin ZHANG Lin LI Xiwen LIU Yan ZENG | 2011 | Chinese Journal of Library and Information Science2011，，Z1： | 2 |
| 15 | An in vitro model of human dopaminergic neurons derived from embryonic stem cells: MPP + toxicity and GDNF neuroprotection 显示文摘 | Zeng XianMin Chen Jia Deng XiaoLin | 2006 | Neuropsychopharmacology2006，31，12： | 1 |
| 16 | Bacterioplankton community structure in a eutrophic lake in relation to water chemistry显示文摘 | Jin Zeng Liuyan Yang Hongwei Du Lin Xiao Lijuan Jiang Jun Wu Xiaolin Wang | 2009 | World Journal of Microbiology and Biotechnology2009，，5： | 1 |
| 17 | Defining an open access resource strategy for research libraries:Part Ⅱ——Challenges and responses显示文摘Purpose:This paper aims to provide a systematic analysis of challenges and responses of the imminent open access-based environment so as to enable sound development of open access(OA)resource strategies.Design/methodology/approach:A systematic and evidence-based analysis is used to discover,identify,and contextualize the factors that relate or interact.A challenge metric for the overall context and additional frameworks or alternative lists is used for the detailed analysis.Findings:Research libraries are facing a reality conflict between the traditional library solution and the OA solution.New resource strategies are needed but have to be based on an open knowledge infrastructure and a systematic analysis of factors and alternatives.Support for OA publishing is becoming a major task and complicated capabilities involved call for libraries to play a central role.Hybrid collection development should be in place to take full advantages of the open world while ensuring reliable and trusted retrieval,reuse,and preservation.Research limitations:The research covers main developments in US and European countries mostly in scientific fields and for scholarly papers.Practical implications:There are already evidences for sound OA resource policies.With the imminent dominance of OA resources,research libraries should and can set up their OA resource strategies.Originality/value:The paper suggests a factor metric as an analysis framework,presents rationale lists and policies to support OA publishing,and proposes a hybrid collection strategy to plan for collection development,retrieval,and preservation. | Xiaolin ZHANG Yan ZENG Lin LI Xiwen LIU | 2012 | Chinese Journal of Library and Information Science2012，，2： | 1 |
| 18 | Diagnostic significance of hepatitis B viral antigens in patients with glomerulonephritis-associated hepatitis B virus infection显示文摘 | Chenggang Shi Jiyi Huang Xun Liu Xiaolin Zeng Cailian Cheng Qiongli Yin Mei Li Guifeng Cheng | 2012 | Diagnostic Microbiology & Infectious Disease2012，，2： | 1 |
| 19 | A case study and mechanism investigation of typical mortars used on ancient architecture in China显示文摘 | ZENG Yuyao ZHANG Bingjian LIANG Xiaolin | 2008 | Thermoehimica Acta2008，473，12： | 1 |
| 20 | A 3.5-kW near-single-mode oscillating-amplifying integrated fiber laser显示文摘The fiber laser based on an oscillating-amplifying integrated structure has the potential to benefit from the advantages of a fiber laser oscillator and amplifier with the characteristics of strong anti-back-reflected light ability and high efficiency.Here,we achieved a 3.5-kW near-single-mode(M^(2)~1.24)oscillating-amplifying integrated fiber laser with an active fiber length of 8 m in the oscillating section and 17.6 m in the amplifying section.While operating at the maximum power,the optical-to-optical conversion efficiency is 87.0%,and the intensity of stimulated Raman scattering is about23.61 dB lower than that of the signal light.To the best of the authors’knowledge,this is the highest output power of an oscillating-amplifying integrated fiber laser,accompanied with the best beam quality and the highest efficiency. | Lingfa Zeng Xiaolin Wang Baolai Yang Hanwei Zhang Xiaojun Xu | 2021 | High Power Laser Science and Engineering2021，9，3： | 1 |
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