|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Association of miRNA-122-binding site polymorphism at the interleukin-1 a gene and its interaction with hepatitis B virus mutations with hepatocellular carcinoma risk显示文摘 | Yan Du Xue Han Rui Pu Jiaxin Xie Yuwei Zhang Guangwen Cao | 2014 | Frontiers of Medicine2014，8，2： | 9 |
| 2 | Integrated bioinformatics identifies the dysregulation induced by aberrant gene methylation in colorectal carcinoma显示文摘Colorectal carcinoma(CRC)is one of the most common cancers,and is associated with a poor dlinical outcome.The key genes and potential prognostic markers in colorectal carcinoma remain to be identfed and explored for clinical application.DNA expression/methyl-ation profles were downloaded from the Gene Expression Omnibus(GEO)database to identify differentially expressed/methylated genes(DEGs and DEMs).A total of 255 genes and 372 genes were identified as being up-regulated and down-regulated,respectively,in GSE113513,GSE81558,and GSE89076.There were a total of 3350 hypermethylated genes and 443 hypomethylated genes identifed in GSE 48684.Twenty genes were found to be hypermethylated as well as down-regulated,and a functional enrichment analysis revealed that these genes were mainly involved in cancer-related pathways.Among these 20 genes,GPM6A,HAND2 and C2orf40 were related to poor outcomes in cancer patients based on a survival analysis.Concurrent decreases of GPM6A,HAND2 and C2orf40 protein expression were observed in highly-dif ferentiated colorectal carcinoma tissues,and higher expression levels were found in undifferentiated or minimally-differentiated colorectal carcinoma tissues.In conclusion,20 genes were found to be downregulated and hypermethylated in CRC,among which GPM6A,HAND2 and C2orf40 were explored for their potential prognostic value. | Zhenyu Ye Yecheng Li Jiaming Xie Zhenyu Feng Xiaodong Yang Yong Wu Yuwei Pu Jiawei Gao Xiangrong Xu Zhaobi Zhu Wei Li Wei Chen Chungen Xing | 2021 | Genes & Diseases2021，8，4： | 2 |
| 3 | Association of a potential functional pre‐miR‐218 polymorphism and its interaction with hepatitis B virus mutations with hepatocellular carcinoma risk显示文摘 | Yifang Han Rui Pu Xue Han Jun Zhao Weiping Li Jianhua Yin Yuwei Zhang Qiuxia Shen Jiaxin Xie Qi Zhang Shuang Jiang Juhong Li Hongwei Zhang Hongyang Wang Guangwen Cao | 2014 | Liver Int2014，，5： | 1 |
| 4 | HLA-DP Polymorphisms Affect the Outcomes of Chronic Hepatitis B Virus Infections, Possibly through Interacting with Viral Mutations显示文摘 | Qi Zhang Jianhua Yin Yuwei Zhang Yang Deng Xiaowei Ji Yan Du Rui Pu Yifang Han Jun Zhao Xue Han Hongwei Zhang Guangwen Cao | 2013 | Journal of Virology2013，，22： | 1 |
| 5 | Edge computing-Based mobile object tracking in internet of things显示文摘Mobile object tracking,which has broad applications,utilizes a large number of Internet of Things(IoT)devices to identify,record,and share the trajectory information of physical objects.Nonetheless,IoT devices are energy con-strained and not feasible for deploying advanced tracking techniques due to significant computing requirements.To address these issues,in this paper,we develop an edge computing-based multivariate time series(EC-MTS)framework to accurately track mobile objects and exploit edge computing to offload its intensive computation tasks.Specifically,EC-MTS leverages statistical technique(i.e.,vector auto regression(VAR))to conduct arbitrary historical object trajectory data revisit and fit a best-effort trajectory model for accurate mobile object location prediction.Our framework offers the benefit of offloading computation intensive tasks from IoT devices by using edge computing infrastructure.We have validated the efficacy of EC-MTS and our experimental results demon-strate that EC-MTS framework could significantly improve mobile object tracking efficacy in terms of trajectory goodness-of-fit and location prediction accuracy of mobile objects.In addition,we extend our proposed EC-MTS framework to conduct multiple objects tracking in IoT systems. | Yalong Wu Pu Tian Yuwei Cao Linqiang Ge Wei Yu | 2022 | High-Confidence Computing2022，2，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员