|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Two-Stage Hydrogenation Modification of C_9 Petroleum Resin over NiWS/γ-Al_2O_3 and PdRu/γ-Al_2O_3 Catalysts in Series显示文摘Hydrogenation modification is one of the most important ways to produce high-quality petroleum resin.The colorless C9 petroleum resin(C9PR) was obtained by two-stage catalytic hydrogenation over NiWS/γ-Al2O3 catalyst and PdRu/γ-Al2O3 catalyst connected in series.Via the hydrogenation reaction,aromatic rings in C9PR were converted to alicyclic rings,and its color was reduced from Gardner color grade No.11 to Gardner color grade No.0.The optimum Ni/W atomic ratio was found to be close to 0.23,while the optimum Pd/Ru atomic ratio was close to 3.80.The TEM results showed that the morphology and size of sulfide or metal particles of the two kinds of catalysts remained almost unchanged after the reaction was carried our for 1 204 hours,attesting to their good catalytic stability. | Yu Lujun Jiang Dahao Xu Jiao Ma Lei Li Xiaonian | 2012 | China Petroleum Processing & Petrochemical Technology2012，14，3： | 7 |
| 2 | Inactivity of YGL082W in vitro due to impairment of conformational change in the catalytic center loop显示文摘MINDY-1 is a recently discovered new family of deubiquitinating enzymes(DUB),but one of its yeast homologs,YGL082 W,does not show any DUB activity in vitro.Sequence alignment shows that YGL082 W possesses the correct catalytic triad,and yet did not catalyze either the hydrolysis of di-ubiquitin,crosslinking with C-terminally propargylated ubiquitin,or hydrolysis of ubiquitin-7-amino-4-methylcoumarin.After obtaining a crystal structure of the catalytic domain of YGL082 W,we identified an interesting difference between the catalytic center loop of YGL082 W and that of its human homolog MINDY-1.Because the conformation of the catalytic center loop was previously reported to be important for the deubiquitination activity of MINDY-1,we hypothesized that Glu27(instead of the corresponding Pro136 in MINDY-1) of the catalytic center loop of YGL082 W may impair the conformational change and account for the lack of activity.This hypothesis was supported by homology modeling and molecular dynamics simulations,which showed that the Pro-to-Glu mutation(P136 E mutation for MINDY-1) creates a hydrogen bond that inhibits the conformation change of the catalytic center loop of MINDY-1.Further experiments through site-directed mutation validated this hypothesis,showing that the P27 E mutation caused MIY1(a homologous active DUB from yeast) to lose activity. | Lining Lu Yu Guo Tian Wang Lujun Liang Suwen Zhao Feng Wang Lei Liu | 2020 | Science China Chemistry2020，63，2： | 1 |
| 3 | Raceway pond cultivation of a new Arthrospira sp.ZJWST-S1 in digested piggery wastewater treated by MBR and ozonation显示文摘A new Arthrospira strain named Arthrospira sp.ZJWST-S1 was isolated from a local digested piggery wastewater(DPW)storage pool in Jiaxing City,Zhejiang Province,China.It possessed good stain resistance against contaminants in DPW,which was pretreated with a membrane bioreactor(MBR).The strain was identified as Arthrospira platensis(A.platensis)based on its morphological characteristics and the 16S rDNA sequencing analysis.The effect of chrominance on growth of A.platensis ZJWST-S1 was investigated in a field raceway pond filled with MBR effluent or MBR effluent decolorized with ozonation.After ozonation,the chrominance of MBR effluent was decreased from 700 mg Pt/L to 150 mg Pt/L.Two runs of cultivation showed that A.platensis ZJWST-S1 grew faster in the ozone decolorized MBR effluent,the averaged biomass concentration being 0.907 g/L after 10 days of cultivation,close to that in a Zarrouk medium(0.969 g/L).By comparison,the biomass grew much slower in the non-decolorized MBR effluent(0.624 g/L).The pollutant removal was also benefited from the accelerative growth of A.platensis ZJWST-S1 in the decolorized MBR effluent.Almost all ammonium,61.2%of nitrate and 68.1%of phosphate were removed by the A.platensis ZJWST-S1 in the decolorized MBR effluent,much higher than the corresponding values of almost all ammonium,25.4%of nitrate and 36.5%of phosphate in the MBR effluent.Furthermore,the Arthrospira biomass harvested from the ozone decolorized MBR effluent after 10 d cultivation was with crude protein content of 59.1%±3.5%in dry algae powder.The content of Pb,As,Cd and Hg in biomass was also low enough to meet the Chinese Arthrospira Standard for Animal Feed(GB/T 17243-1998).This study showed that the new strain A.platensis ZJWST-S1 possessed potential to be used for producing animal feed and simultaneous removal of nitrogen and phosphorus in DPW. | Liu Rui Yu Qiangqiang Guo Qingqing Zheng Wei Wang Genrong Chen Lujun | 2017 | International Journal of Agricultural and Biological Engineering2017，10，1： | 1 |
| 4 | 8-Oxoguanine DNA glycosylase protects cells from senescence via the p53-p21 pathway显示文摘Cellular senescence is an important factor leading to pulmonary fibrosis.Deficiency of 8-oxoguanine DNA glyco-sylase(OGG1)in mice leads to alleviation of bleomycin(BLM)-induced mouse pulmonary fibrosis,and inhibition of the OGG1 enzyme reduces the epithelial mesenchymal transition(EMT)in lung cells.In the present study,we find decreased expression of OGG1 in aged mice and BLM-induced cell senescence.In addition,a decrease in OGG1 expression results in cell senescence,such as increases in the percentage of SA-β-gal-positive cells,and in the p21 and p-H2AX protein levels in response to BLM in lung cells.Furthermore,OGG1 promotes cell transformation in A549 cells in the presence of BLM.We also find that OGG1 siRNA impedes cell cycle progression and inhibits the levels of telomerase reverse transcriptase(TERT)and LaminB1 in BLM-treated lung cells.The increase in OGG1 expression results in the opposite phenomenon.The mRNA levels of senescence-associated secretory phenotype(SASP)components,including IL-1α,IL-1β,IL-6,IL-8,CXCL1/CXCL2,and MMP-3,in the absence of OGG1 are obviously increased in A549 cells treated with BLM.Interestingly,we demonstrate that OGG1 binds to p53 to inhibit the activation of p53 and that silencing of p53 reverses the inhibition of OGG1 on senescence in lung cells.Ad-ditionally,the augmented cell senescence is shown in vivo in OGG1-deficient mice.Overall,we provide direct evidence in vivo and in vitro that OGG1 plays an important role in protecting tissue cells against aging associated withthep53pathway. | Shenglan Gao Lujun Chen Ziying Lin Zhiliang Xu Yahong Wang Huayu Ling Zijun Wu Yu Yin Weimin Yao Keng Wu Gang Liu | 2024 | Acta Biochimica et Biophysica Sinica2024，56，2： | 0 |
| 5 | Photonic slide rule with metasurfaces显示文摘As an elementary particle,a photon that carries information in frequency,polarization,phase,and amplitude,plays a crucial role in modern science and technology.However,how to retrieve the full information of unknown photons in.an ultracompact manner over broad bandwidth remains a challenging task with growing importance.Here,we demonstrate a versatile photonic slide rule based on an ll-silicon metasurface that enables uS to reconstruct incident photons'frequency and polarization state.The underlying mechanism relies on the coherent interactions of frequency-driven phase diagrams which rotate at various angular velocities within broad bandwidth.The rotation direction and speed are determined by the topological charge and phase dispersion.Specificall,our metasurface leverages both achromatically focusing and azimuthally evolving phases with topological charges+1 and-1 to ensure the confocal annular intensity ditributions.The combination of geometric phase and interference holography allows the joint manipulations of two distinct group delay coverages to realize angle-resolved in-pair spots in a.transverse manner-a behavior that would disperse along longitudinal direction in conventional implementations.The spin-orbital coupling between the incident photons and vortex phases provides routing for the simultaneous identifcation of the photons'frequency and circular polarization state through recognizing the spots'locations.Our work provides an analog of the conventional slide rule to flexibly characterize the photons in an ultracompact and multifunctional way and may find applications in integrated optical circuits or pocketable devices. | Feilong Yu Jin Chen Lujun Huang Zengyue Zhao Jiuxu Wang Rong Jin Jian Chen Jian Wang Andrey E.Miroshnichenko Tianxin Li Guanhai Li Xiaoshuang Chen Wei Lu | 2022 | Light(Science & Applications)2022，11，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员