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| 1 | Dynamic changes in soil chemical properties and microbial community structure in response to different nitrogen fertilizers in an acidified celery soil显示文摘To determine the effects of different kinds of nitrogen fertilizer,especially high-efficiency slowrelease fertilizers,on soil pH,nitrogen(N)and microbial community structures in an acidic celery soil,four treatments(CK,no N fertilizer;NR,urea;PE,calcium cyanamide fertilizer;and SK,controlled-release N fertilizer)were applied,and soil pH,total soil N,inorganic N,and soil microbial biomass C were analyzed.Phospholipid fatty acids(PLFAs)were extracted and detected using the MIDI Sherlock microbial identification system.The PE treatment significantly improved soil pH,from 4.80 to>6.00,during the whole growth period of the celery,and resulted in the highest celery yield among the four treatments.After 14 d application of calcium cyanamide,the soil nitrate content significantly decreased,but the ammonium content significantly increased.The PE treatment also significantly increased soil microbial biomass C during the whole celery growth period.Canonical variate analysis of the PLFA data indicated that the soil microbial community structure in the CK treatment was significantly different from those in the N applied treatments after 49 d fertilization.However,there was a significant difference(P<0.05)in soil microbial community structure between the PE treatment and the other three treatments at the end of the experiment.Calcium cyanamide is a good choice for farmers to use on acidic celery land because it supplies sufficient N,and increases soil pH,microbial biomass and the yield of celery. | Yuping Wu Jiangxing Wu Yongjun Ma Ying Lian Hui Sun Danchao Xie Yaying Li Philip C.Brookes Huaiying Yao | 2019 | Soil Ecology Letters2019，1，3： | 7 |
| 2 | miR-146a-5p acts as a negative regulator of TGF-β signaling in skeletal muscle after acute contusion显示文摘成长证据在表明小径的应力建议 microRNAs (miRNAs ) 的重要性。转变生长因素 --(TGF-) 是在尖锐殴打以后支持骨胳的肌肉纤维变性的发展的有势力 cytokine。然而, miRNAs 怎么涉及 TGF- 发信号并且授与 TGF 的坚韧性 -- 导致的 fibrotic 反应尚待充分被阐明。这里,我们证明 miR-146a-5p (miR-146 ) 层次在尖锐肌肉殴打以后在一个 fibrotic 老鼠模型被减少。它也被发现那个 TGF- 处理减少在在一个剂量依赖者和时间依赖者举止的 vitro 的 miR-146 的表示。另外, Smad3 和 Samd4 的 overexpression,在 TGF- 发信号的二个关键播放器,在肌肉房间压制了 miR-146 的表达式。miR-146 的 Overexpression 在 vitro 并且在 vivo 禁止了纤维变性标记的表情。而且,在肌肉房间的 miR-146 的表示的增加能在纤维变性标记的表情上稀释 TGF- 的效果。机械学的分析表明 Smad4 是在肌肉房间的 miR-146 的一个直接目标。而且, miR-146 的 anti-fibrotic 效果能被 Smad4 的 overexpression 在 vivo 堵住。这些结果建议 Smad4 由在骨胳的肌肉的 miR-146 是下面调整的。一起拿,我们的结果显示 anti-fibrotic miR-146 是 TGF- 发信号的一个部件。它由 Smad 蛋白质是下面调整的,并且能禁止 Smad4 的表示。我们的学习建议 miR-146 可能有一个治疗学的潜力在损害以后减少骨胳的肌肉纤维变性。 | Yaying Sun Yan Li Hui Wang Hongyun Li Shaohua Liu Jiwu Chen Hao Ying | 2017 | Acta Biochimica et Biophysica Sinica2017，49，7： | 5 |
| 3 | Mantle Source Components and Magmatic Evolution for the Comei Large Igneous Province:Evidence from the Early Cretaceous Niangzhong Mafic Magmatism in Tethyan Himalaya显示文摘The Niangzhong diabase dikes,dated at 138.1±0.4 Ma,are located within the outcrop area of the Comei large igneous province(LIP).These diabase samples can be divided into two groups:samples in Group 1 show varying MgO(1.50 wt.%-10.25 wt.%)and TiO_(2)(0.85 wt.%-4.63 wt.%)contents,and enriched initial isotope compositions(^(87)Sr/^(86)Sr(t)=0.7056-0.7112,ε_(Nd)(t)=-0.3-+3.8),with OIB-like REEs and trace elements patterns,resulting from low degree melting of garnet-bearing lherzolite mantle sources;in contrast,samples in Group 2 show limited MgO(4.14 wt.%-7.75 wt.%)and TiO_(2)(0.98 wt.%-1.69 wt.%)contents,and depleted initial isotope compositions(^(87)Sr/^(86)Sr(t)=0.7075-0.7112,ε_(Nd)(t)=+5.5-+6.2),with N-MORB-like REEs and trace elements patterns,resulting from relatively high degree melting of spinel-bearing lherzolite mantle source.Combined with the published representative data about Comei LIP,we summarize that the source components for Comei LIP products include OIB end-member,enriched OIB end-member,and N-MORB end-member,respectively.Melts modeling suggests that magmas in the Comei LIP evolve in a relatively high oxygen fugacity condition,which influenced their fractionation sequences and led to systematic changes of TiO_(2)contents,Ti/Y and Ti/Ti*ratios.From the spatial and temporal distribution of above three end-member samples,deep process of Kerguelen plume during the Comei LIP formation can be interpreted as the interaction among the Kerguelen plume,the overlying lithospheric mantle,and the upwelling asthenosphere.The magmatism of Comei LIP began at~140 Ma and then lasted and peaked at~132 Ma with the progressively lithospheric thinning of eastern Gondwana upon the impact of Kerguelen plume. | Yaying Wang Lingsen Zeng Kejun Hou Li'e Gao Qian Wang Linghao Zhao Jiahao Gao Guangxu Li | 2022 | Journal of Earth Science2022，33，1： | 3 |
| 4 | Exosome-mediated cellular crosstalk within the tumor microenvironment upon irradiation显示文摘Radiotherapy is one of the most effective treatment methods for various solid tumors.Bidirectional signal transduction between cancer cells and stromal cells within the irradiated microenvironment is important in cancer development and treatment responsiveness.Exosomes,initially considered as'garbage bins'for unwanted from cells,are now understood to perform a variety of functions in interactions within the tumor microenvironment.Exosome-mediated regulation processes are rebuilt under the irradiation stimuli,because the exosome production,uptake,and contents are markedly modified by irradiation.In turn,irradiation-modified exosomes may modulate the cell response to irradiation through feedback regulation.Here,we review current knowledge and discuss the roles of exosome-mediated interactions between cells under radiotherapy conditions. | Chuanshi He Ling Li Linlin Wang Wanrong Meng Yaying Hao Guiquan Zhu | 2021 | Cancer Biology & Medicine2021，18，1： | 3 |
| 5 | Variations in the biomass of Eucalyptus plantations at a regional scale in Southern China显示文摘We quantified deviations in regional forest biomass from simple extrapolation of plot data by the biomass expansion factor method(BEF) versus estimates obtained from a local biomass model,based on large-scale empirical field inventory sampling data.The sources and relative contributions of deviations between the two models were analyzed by the boosted regression trees method.Relative to the local model,BEF overestimated accumulative biomass by 22.12%.The predominant sources of the total deviation (70.94%) were stand-structure variables.Stand age and diameter at breast height are the major factors.Compared with biotic variables,abiotic variables had a smaller overall contribution (29.06%),with elevation and soil depth being the most important among the examined abiotic factors.Large deviations in regional forest biomass and carbon stock estimates are likely to be obtained with BEF relative to estimates based on local data.To minimize deviations,stand age and elevation should be included in regional forest-biomass estimation. | Quanyi Qiu Guoliang Yun Shudi Zuo Jing Yan Lizhong Hua Yin Ren Jianfeng Tang Yaying Li Qi Chen | 2018 | Journal of Forestry Research2018，29，5： | 2 |
| 6 | Shadow–highlight feature matching automatic small crater recognition using high-resolution digital orthophoto map from Chang’E Missions显示文摘This paper introduces a new method of small lunar craters’ automatic identification, using digital orthophoto map(DOM) data. The core of the approach is the fact that the lunar exploration DOM data reveal contrasting highlight and shadow characteristics of small craters under sunlight irradiation. This research effort combines image processing and mathematical modeling. Overall it proposes a new planetary data processing approach, to segment and extract the highlight and shadow regions of small craters,using the image gray frequency(IGF) statistical method.IGF can also be applied to identify the coupling relationships between small craters’ shape and their relative features. This paper presents the highlight and shadow pair matching(HSPM) model which manages to perform highprecision automatic recognition of small lunar craters.Testing was performed using the DOM data of Chang’E-2(CE-2). The results have shown that the proposed method has a high level of successful detection rate. The proposed methodology that uses DOM data can complement the drawbacks of the digital elevation model(DEM) that has a relatively high false detection rate. A hybrid fusion model(FUM) that combines both DOM and DEM data, was carried out to simultaneously identify small, medium, and large-sized craters. It has been proven that the FUM generally shows stronger recognition ability compared to previous approaches and it can be adapted for high precision identification of craters on the whole lunar surface.The results meet the requirements for a reliable and accurate exploration of the Moon and the planets. | Wei Zuo Chunlai Li Lingjie Yu Zhoubin Zhang Rongwu Wang Xingguo Zeng Yuxuan Liu Yaying Xiong | 2019 | Acta Geochimica2019，38，4： | 1 |
| 7 | Partial oxidation of methane with air or O 2 and steam to synthesis gas over a Ni-based catalyst显示文摘 | Ji Yaying Li Wenzhao Chen Yanxin | 2000 | J Nat Gas Chem2000，9，4： | 1 |
| 8 | Nitrate enhances N 2 O emission more than ammonium in a highly acidic soil显示文摘 | Ying Huang Yaying Li Huaiying Yao | 2014 | Journal of Soils and Sediments2014，，1： | 1 |
| 9 | Late Ordovician to Early Silurian Tectonic Events in the Himalayan Terrain显示文摘Objective The Himalaya terrain together with the ribbon terrains(e.g.,Lhasa,Qiangtang,and Sibumasu blocks)of the Gondwana supercontinent has experienced episodic tectonic events since the Neoproterozoic.However,almost not any documentation with regard to the tectonic processes links the peri-Gondwana subduction | GAO Li'e ZENG Lingsen HU Guyue WANG Yuhua GAO Jiahao SHANG Zhen WANG Yaying | 2016 | Acta Geologica Sinica(English Edition)2016，90，3： | 1 |
| 10 | Partial oxidation of methane with air or and steam to synthesis gas over a Ni - based catalyst显示文摘 | Ji Yaying Li Wenzhao Chen Yanxin | 2000 | Journal of Natural Gas Chemistry2000，9，： | 1 |
| 11 | Plasma from healthy donors protects blood-brain barrier integrity via FGF21 and improves the recovery in a mouse model of cerebral ischaemia显示文摘Background Healthy plasma therapy reverses cognitive deficits and promotes neuroplasticity in ageing brain disease.However,whether healthy plasma therapy improve blood-brain barrier integrity after stroke remains unknown.Methods Here,we intravenously injected healthy female mouse plasma into adult female ischaemic stroke C57BL/6 mouse induced by 90 min transient middle cerebral artery occlusion for eight consecutive days.Infarct volume,brain atrophy and neurobehavioural tests were examined to assess the outcomes of plasma treatment.Cell apoptosis,blood-brain barrier integrity and fibroblast growth factor 21 knockout mice were used to explore the underlying mechanism.Results Plasma injection improved neurobehavioural recovery and decreased infarct volume,brain oedema and atrophy after stroke.Immunostaining showed that the number of transferase dUTP nick end labelling+/NeuN+cells decreased in the plasma-injected group.Meanwhile,plasma injection reduced ZO-1,occluding and claudin-5 tight junction gap formation and IgG extravasation at 3 days after ischaemic stroke.Western blot results showed that the FGF21 expression increased in the plasma-injected mice.However,using FGF21 knockout mouse plasma injecting to the ischaemic wild-type mice diminished the neuroprotective effects.Conclusions Our study demonstrated that healthy adult plasma treatment protected the structural and functional integrity of blood-brain barrier,reduced neuronal apoptosis and improved functional recovery via FGF21,opening a new avenue for ischaemic stroke therapy. | Muyassar Mamtilahun Lu Jiang Yaying Song Xiaojing Shi Chang Liu Yixu Jiang Lidong Deng Haoran Zheng Hui Shen Yongfang Li Zhijun Zhang Yongting Wang Yaohui Tang Guo-Yuan Yang | 2021 | Stroke & Vascular Neurology2021，6，4： | 1 |
| 12 | Elusive Cenozoic Metamorphism in Mafic Dike Swarms within the Tethyan Himalaya, Southern Tibet显示文摘Mafic dike swarms are well-developed within the Tethyan Himalaya,southern Tibet,in response to the breakup of Gondwana supercontinent,seafloor spreading of the Tethyan Ocean,and forearc hyperextension during | ZENG Lingsen WANG Yuhua GAO Li'E WANG Yaying | 2016 | Acta Geologica Sinica(English Edition)2016，90，S1： | 1 |
| 13 | Catalytic partial oxidation of methane to synthesis gas over Ni/γ-Al2O3 catalyst in a fluidized-bed显示文摘 | Yaying Ji Wenzhan Li Hengyong Xu | 2001 | Appl Catal A:Gen2001，213，： | 1 |
| 14 | Partial oxidation of methane with air or 02 and steam to synthesis gas over a Ni-based catalyst显示文摘 | Ji Yaying Li Wenzhao Chen Yanxin | 2000 | Journal of Natural Gas Chemistry2000，9，4： | 1 |
| 15 | A leap by the rise of solid-state electrolytes for Li-air batteries显示文摘Li-air batteries have attracted extensive attention because of their ultrahigh theoretical energy density. However, the potential safety hazard of flammable organic liquid electrolytes hinders their practical applications. Replacing liquid electrolytes with solidstate electrolytes(SSEs) is expected to fundamentally overcome the safety issues. In this work, we focus on the development and challenge of solid-state Li-air batteries(SSLABs). The rise of different types of SSEs, interfacial compatibility and verifiability in SSLABs are presented. The corresponding strategies and prospects of SSLABs are also proposed. In particular, combining machine learning method with experiment and in situ(or operando)techniques is imperative to accelerate the development of SSLABs. | Kecheng Pan Minghui Li Weicheng Wang Shuochao Xing Yaying Dou Shasha Gao Zhang Zhang Zhen Zhou | 2023 | Green Energy & Environment2023，8，4： | 0 |
| 16 | Alleviating glucose repression and enhancing respiratory capacity to increase itaconic acid production显示文摘The Crabtree effect products ethanol and acetic acid can be used for itaconic acid(IA)production in Saccharomyces cerevisiae.However,both the IA synthesis and oxidative phosphorylation pathways were hampered by glucose repression when glucose was used as the substrate.This study aimed to improve IA titer by increasing gene expressions related to glucose derepression without impairing yeast growth on glucose.Engineering the acetyl-CoA synthesis pathway increased the titer of IA to 257 mg/L in a urea-based medium.Instead of entire pathway overexpression,we found that some signaling pathways regulating glucose repression were effective targets to improve IA production and respiratory capacity.As a consequence of the reduced inhibition,IA titer was further increased by knocking out a negative regulator of the mitochondrial retrograde signaling MKS1.SNF1/MIG1 signaling was disturbed by deleting the hexokinase HXK2 or an endoplasmic reticulum membrane protein GSF2.The shaking results showed that XYY286(BY4741,HO::cadA,Y::Dz.ada,208a::Mt.acs,Δhxk2,pRS415-cadA,pRS423-aac2)accumulated 535 mg/L IA in 168 h in the YSCGLU medium.qRT-PCR results verified that deletion of MKS1 or HXK2 upregulated the gene expressions of the IA synthesis and respiratory pathways during the growth on glucose. | Yaying Xu Zhimin Li | 2023 | Synthetic and Systems Biotechnology2023，8，1： | 0 |
| 17 | New dual functional CYP450 gene involves in isoflavone biosynthesis in Glycine max L.显示文摘Glycine max L.accumulates a large amount of isoflavonoid compounds,which is beneficial for plant defense,plant-microbe symbiotic interactions,and human health.Several CYP450 subfamily genes are involved in the flavonoid biosynthetic pathway in plants.In the present study,we found 24 CYP82 subfamily genes were differentially expressed in various tissues of soybean,in Phytophthora sojae-infected soybean varieties and in soybean hairy roots treated with cell wall glucan elicitor.Six of them(GmCYP82A2,GmCYP82A3,GmCYP82A4,GmCYP82A23,GmCYP82C20 and GmCYP82D26)were co-expressed with other known isoflavonoid pathway genes in soybean.Their enzymatic activity in yeast feeding assays showed that only GmCYP82D26 was able to convert naringenin to daidzein with both aryl migration and dehydration function.When GmCYP82D26 was over-expressed in soybean hairy roots,the contents of the two major isoflavonoid aglycones in soybean(daidzein and genistein)were reduced,but total flavonoids were not affected.When GmCYP82D26 was suppressed by RNAi in the hairy roots,daidzein content was decreased but genistein content was increased,with unchanged total flavonoid content.GmCYP82D26 was found to be localized in the endoplasmic reticulum at subcellular level when transiently expressed in tobacco leaf epidermis.GmCYP82D26 gene was preferentially expressed in roots,with low expression level in other tissues in soybean.Homology modeling and molecular docking showed that GmCYP82D26 could form hydrogen bond with both HEM and naringenin at C5-OH and C4 carbonyl.All these results indicated that GmCYP82D26 possesses new and dual enzymatic activity,which bridges the two branches(daidzein and genistein branch)of isoflavonoid pathway in soybean. | Yaying Xia Chunfeng He Su Yan Jinyue Liu Haijun Huang Xue Li Qian Su Wenbo Jiang Yongzhen Pang | 2023 | Synthetic and Systems Biotechnology2023，8，1： | 0 |
| 18 | 阳离子通道TRPV在醛缩酶和AMPK感知葡萄糖过程中起必须的作用显示文摘文章简介在激活AMPK的溶酶体途径感应葡萄糖供给下降的过程中,果糖-1,6-二磷酸醛缩酶(aldolase)起关键作用。然而,醛缩酶是如何把其与果糖-1,6-二磷酸结合的减少的信息传导引起AMPK活化的机制还尚未清楚。 | Mengqi Li Chen-Song Zhang Yue Zong Jin-Wei Feng Teng Ma Meiqin Hu Zhizhong Lin Xiaotong Li Changchuan Xie Yaying Wu Dong Jiang Ying Li Cixiong Zhang Xiao Tian Wen Wang Yanyan Yang Jie Chen Jiwen Cui Yu-Qing Wu Xin Chen Qing-Feng Liu Jianfeng Wu Shu-Yong Lin Zhiyun Ye Ying Liu Hai-Long Piao Li Yu Zhuan Zhou Xiao-Song Xie D.Grahame Hardie 林圣彩 | 2020 | 科学新闻2020，，2： | 0 |
| 19 | Influence of Moxibustion of Complementary Acupoints on Analgesic Effect and Mast Cell Function in CIA Rats显示文摘[Objectives]To explore the moxibustion effect and mechanism of'Complementary Acupoints'on rheumatoid arthritis(RA).[Methods]A total of 32 Wistar rats were randomly divided into 4 group:normal control(K),model group(M group),'the Complementary Acupoints'Yanglingquan and Yinlingquan group(AB group),Shenshu and Zusanli group(CD group),with 8 rats in each group.Moxibustion was performed using refined moxa floss(2 mg/pc)on acupoints in both sides every other day,5 pieces for each acupoint,and implemented for 10 times.Before and after the modeling and after the intervention,the left foot sole thermal pain threshold of each group was measured.After the intervention,the rats'left paws were examined by X-ray to detect the number of mast cells(MCs)and degranulation in the affected area of the foot.[Results]The thermal pain threshold of the model group was lower than that of the K group(P<0.05).The number of MC in the affected area and the degranulation were increased.After the moxibustion intervention,the thermal pain threshold of the AB and CD groups was higher than that of the M group(P<0.05);the number of MCs and degranulation were decreased compared with M group,and the degree of reduction was better than that of CD group.The data of foot and claw showed that the foot and paw soft tissue swelling,bone and joint deformity and bone destruction were better in AB and CD groups were more relieved than that in M group.[Conclusions]The moxibustion of Complementary Acupoints can effectively intervene with RA of rats,and its mechanism may be closely related to the MC degranulation. | Haiyan LI Hengkang ZHU Taotao CUI Yaying CUI Zhixin YANG | 2020 | Medicinal Plant2020，11，6： | 0 |
| 20 | Main environmental drivers of abundance,diversity and community structure of comammox Nitrospira in paddy soils显示文摘The recently discovered complete ammonia oxidizers comammox Nitrospira contain clades A and B that can establish an independent one-step nitrification process;however,little is known about their environmental drivers or habitat distributions in agricultural soils.Previous studies on comammox Nitrospira in paddy soils have mainly focused on small-scale samples,and there is a lack of multisite research on comammox Nitrospira in paddy soils.In this study,we conducted a survey of 36 paddy soils to understand the community structure,abundance,and diversity of comammox Nitrospira and the degree to which they are affected by environmental factors at a large scale.Comammox Nitrospira were found to be widely distributed among the paddy soils.The abundance of comammox Nitrospira clade A was mostly lower than that of clade B,whereas its diversity was mostly higher than that of clade B.Correlation analysis showed that multiple factors affected(P<0.05)the abundance of comammox Nitrospira,including soil pH,organic matter,total carbon,and total nitrogen,latitude,mean annual temperature,and mean annual precipitation.Moreover,there was a clear relationship between the comammox Nitrospira community and habitat,indicating that some amplicon sequence variants(ASVs)had a unique dominant position in specific habitats.Phylogenetic analysis showed that the ASVs of comammox Nitrospira clade A clustered with the known sequences in the paddy soils and were significantly different from the known sequences in other habitats,which may be related to the unique paddy field habitat.In contrast,comammox Nitrospira clade B showed no clear habitat dependence.These results support the wide distribution and high abundance of comammox Nitrospira in paddy soils and provide novel insights into nitrogen cycling and nutrient management in agricultural ecosystems. | Fuyun GAO Yaying LI Haoxin FAN Jiantao XUE Huaiying YAO | 2023 | Pedosphere2023，33，5： | 0 |
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