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3篇 您的检索式：作者名="Yasuhiro Setoguchi"

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		题名	作者	年代	出处	被引量
	1	Serum Neutrophil Gelatinase-associated Lipocalin(NGAL)Is Elevated in Patients with Asthma and Airway Obstruction显示文摘Neutrophilic airway inflammation is one of the features of severe asthma.Neutrophil gelatinase-associated lipocalin(NGAL),or lipocalin-2,is a glycoprotein associated with neutrophilic inflammation and can be detected in blood.Recently,blood NGAL levels have been reported to be elevated in chronic obstructive pulmonary disease.However,the clinical significance of serum NGAL levels in patients with asthma has not been elucidated.The aim of this study was to explore the association between serum NGAL level and clinical parameters in patients with asthma.Sixty.one non-smoking people with stable asthma were enrolled in this study.All patients underwent blood ollction and pulmonary function tests.The associations between serum NGAL levels and clinical parameters were analyzed retrospectively.Serum NGAL levels in patients with asthma and obstructive ventilatory defect were higher than those in patients with asthma without obstructive ventilatory defect(76.4±51.4 ng/mL vs.39.3±27.4 ng/mL,P=0.0019).Serum NGAL levels were correlated with forced expired flow at 50%of vital capacity%predicted and forced expired flow at 75%of vital capacity%predicted(r=-0.3373,P=0.0078 and r=0.2900,P=0.0234,respectively).Results of a multiple regression analysis demonstrated that serum NGAL level was independently associated with obstructive ventilatory defect.Serum NGAL levels were elevated in patients with asthma and obstructive ventilatory defect.NGAL may be involved in airway remodeling possibly mediated by neutrophilic inflammation in asthma.	Junichiro Kawagoe Yuta Kono Yuki Togashi Mayuko Ishiwari Kazutoshi Toriyama Chika Yajima Hideaki Nakayama Satoshi Kasagi Shinji Abe Yasuhiro Setoguchi	2021	Current Medical Science2021，41，2：	5
	2	Extended survival observed in adoptive activated T lymphocyte immunotherapy for advanced lung cancer: results of a multicenter historical cohort study显示文摘	Kazuro Iwai Kenzo Soejima Shoji Kudoh Yoshimasa Umezato Toru Kaneko Kouji Yoshimori Hitoshi Tokuda Tetsuo Yamaguchi Akira Mizoo Yasuhiro Setoguchi Takashi Kamigaki Katsunada Fujimoto Shigenori Goto	2012	Cancer Immunology Immunotherapy2012，，10：	1
	3	Pharmacological inhibition of the Hedgehog pathway prevents human rhabdomyosarcomacell growth显示文摘	Naoya Kawabata Kosei Ijiri Yasuhiro Ishidou Takuya Yamamoto Hiroko Nagao Satoshi Nagano Shingo Maeda Setsuro Komiya Takao Setoguchi	2011	International Journal of Oncology2011，，4：	1

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