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| 1 | Laboratory investigation on the properties of asphalt mixtures modified with double-adding admixtures and sensitivity analysis显示文摘In order to improve the high temperature stability and low temperature cracking resistance of asphalt mixtures,two varieties of admixtures(anti-rutting agent and lignin fiber) were selected and then combined.This is called double-mixture technology.A series of tests about pavement performance of base asphalt mixtures and asphalt mixtures with admixture of anti-rutting agent or lignin fiber were conducted.Meanwhile sensitivity analyses were used to study the influence of three factors(i.e.,asphalt grade,aggregate type and gradation) on the high and low temperature performance and water stability of said asphalt mixtures.Test results indicated that the dynamic stability,residual stability,TSR and low temperature failure strain of asphalt mixtures have increased significantly with the additions of 0.40% anti-rutting agent and 0.36% lignin fiber.These results show that the high and low temperature and water stabilities of asphalt mixtures improve obviously.This supports the beneficial comprehensive effect of the double admixture.The problem of improving the asphalt mixtures performance with a single admixture is solved,in addition to also improving other pavement performance.Based on the sensitivity analysis,the most influential factors of dynamic stability,low temperature failure strain and TSR are the gradation,followed by asphalt grade and aggregate type. | Zhen Fu Yanni Dang Bo Guo Yue Huang | 2016 | Journal of Traffic and Transportation Engineering(English Edition)2016，3，5： | 17 |
| 2 | 特高压直流换流变压器试验标准和要求的探讨(英文)显示文摘中国目前正在建设两个打破世界纪录的特高压直流输电工程,一是±800kV云南—广东直流输电工程,二是±800kV向家坝—上海直流输电工程。文章探讨了这两项直流输电工程的换流变压器在型式试验期间遇到的一些技术问题。该试验是按照客户基于相关的IEC标准提出的项目设备规范要求实施的,因此研究结果与相关的IEC标准及该试验的实际经验有关。基于这些研究结果,KEMA提出了对将来工程中换流变压器的试验要求的建议以及针对个别具体试验的改进措施。有一点要强调的,KEMA所推荐的变压器试验顺序值得遵循,因为在这一方面IEC标准是不明确的。 | Yanny Fu Peter Vaessen Wilco Rorijs Mark Louwerse | 2009 | 南方电网技术2009，3，3： | 16 |
| 3 | 特高压直流输电系统晶闸管换流阀和换流变压器设计审核及验证(英文)显示文摘中国目前正在建设两个打破世界纪录的特高压直流输电工程,一是±800kV5000MW云南—广东直流输电工程,二是±800kV6400MW向家坝—上海直流输电工程。KEMA作为独立监理参与了这两项工程。文章叙述了为这两项直流输电工程所做的±800kVUHVDC晶闸管换流阀和换流变压器设计审核和验证遇到的一些技术问题。从设计审核和验证中发现,UHVDC换流变压器由于其模块设计而比晶闸管换流阀更具挑战性。KEMA对晶闸管换流阀和换流变压器的试验方法提出了一系列建议。 | Yanny Fu Peter Vaessen | 2010 | 南方电网技术2010，4，2： | 3 |
| 4 | An algorithm for preferential selection of spectroscopic targets in LEGUE显示文摘We describe a general target selection algorithm that is applicable to any survey in which the number of available candidates is much larger than the number of objects to be observed. This routine aims to achieve a balance between a smoothly- varying, well-understood selection function and the desire to preferentially select certain types of targets. Some target-selection examples are shown that illustrate different possibilities of emphasis functions. Although it is generally applicable, the algorithm was developed specifically for the LAMOST Experiment for Galactic Understanding and Exploration (LEGUE) survey that will be carried out using the Chinese Guo Shou Jing Telescope. In particular, this algorithm was designed for the portion of LEGUE targeting the Galactic halo, in which we attempt to balance a variety of science goals that require stars at fainter magnitudes than can be completely sampled by LAMOST. This algorithm has been implemented for the halo portion of the LAMOST pilot sur- vey, which began in October 2011. | Jeffrey L. Carlin Sebastien Lepine Heidi Jo Newberg Li-Cai Deng Timothy C. Beers Yu-Qin Chen Norbert Christlie Xiao-Ting Fu Shuang Gao Carl J. Grillmair PuragraGuhathakurta Zhan-Wen Han Jin-Liang Hou Hsu-Tai Lee Jing Li Chao Liu Xiao-Wei Liu Kai-Ke Pan J. A. Sellwood Hong-Chi Wang Fan Yang Brian Yanny Yue-Yang Zhan Zheng Zheng Zi Zhu | 2012 | Research in Astronomy and Astrophysics2012，12，7： | 1 |
| 5 | Exploring the attenuation mechanisms of Dalbergia odorifera leaves extract on cerebral ischemia-reperfusion based on weighted gene co-expression network analysis显示文摘The attenuation function of Dalbergia odorifera leaves on cerebral ischemia-reperfusion(I/R)is little known.The candidate targets for the Chinese herb were extracted from brain tissues through the high-affinity chromatography.The molecular mechanism of D.odorifera leaves on cerebral I/R was investigated.Methods:Serial affinity chromatography based on D.odorifera leaves extract(DLE)affinity matrices were applied to find specific binding proteins in the brain tissues implemented on C57BL/6 mice by intraluminal middle cerebral artery occlusion for 1 h and reperfusion for 24 h.Specific binding proteins were subjected to mass-spectrometry to search for the differentially expressed proteins between control and DLE-affinity matrices.The hub genes were screened based on weighted gene co-expression network analysis(WGCNA).Then,predictive biology and potential experimental verification were performed for the candidate genes.The protective role of DLE in blood-brain barrier damage in cerebral I/R mice was evaluated by the leakage of Evans blue,western blotting,immunohistochemistry,and immunofluorescent staining.Results:952 differentially expressed proteins were classified into seven modules based on WGCNA under soft threshold 6.Based on WGCNA,AKT1,PIK3CA,NOS3,SMAD3,SMAD1,IL6,MAPK1,TGFBR2,TGFBR1,MAPK3,IGF1R,LRG1,mTOR,ROCK1,TGFB1,IL1B,SMAD2,and SMAD518 candidate hub proteins were involved in turquoise module.TGF-β,MAPK,focal adhesion,and adherens junction signaling pathway were associated with candidate hub proteins.Gene ontology analysis demonstrated that candidate hub proteins were related to the TGF-βreceptor signaling pathway,common-partner SMAD protein phosphorylation,etc.DLE could significantly reduce the leakage of Evans blue in mice with cerebral I/R,while attenuating the expression of occludin,claudin-5,and zonula occludens-1.Western blotting demonstrated that regulation of TGF-β/SMAD signaling pathway played an essential role in the protective effect of DLE.Conclusion:Thus,a number of candidate hub proteins were identified based on DLE affinity chromatography through WGCNA.DLE could attenuate the dysfunction of bloodbrain barrier in the TGF-β/SMAD signaling pathway induced by cerebral I/R. | JINFANG HU JIANGEN AO LONGSHENG FU YAOQI WU FENG SHAO TIANTIAN XU MINGJIN JIANG SHAOFENG XIONG YANNI LV | 2023 | BIOCELL2023，47，7： | 0 |
| 6 | Biochanin A,as the Lrg1/TGF-β/Smad2 pathway blockade,attenuates blood-brain barrier damage after cerebral ischemiareperfusion by modulating leukocyte migration patterns显示文摘Background:Biochanin A is an excellent dietary isoflavone that has the concomitant function of both medicine and foodstuff.The attenuation function of biochanin A on blood-brain barrier(BBB)damage induced by cerebral ischemia-reperfusion remains unclear.Methods:C57BL/6 mice were subjected to 1 h middle cerebral artery occlusion(MCAO)followed by 24 h reperfusion.The infarct volume of the brain was stained by TTC,while leakage of the brain was quantitatively stained by Evans blue,and the neurologic deficit score was measured.Microglial-induced morphologic changes were observed via immunofluorescence staining,and rolling and adhering leukocytes in venules were observed via two-photon imaging,while the inner fluorescein isothiocyanate-albumin of venules were compared with those of surrounding interstitial area through venular albumin leakage.Results:The attenuation effect of biochanin A on tight junction injury was compared in ischemia-reperfusion mice or conventional knockdown of leucine-richα2-glycoprotein 1(Lrg1)mice.Biochanin A could ameliorate BBB injury in mice with cerebral ischemiareperfusion in a dose-dependent manner by strengthening the immunostaining volume of occludin,claudin-5,and zonula occludens-1.The amoeba morphologic changes of microglial combined with the elevated expression of Lrg1 could be relieved under the treatment of biochanin A.Biochanin A played a countervailing role on the rolling leukocytes in the vessel,while the leakage of blood vessels was reduced.Biochanin A diminished its functions to further improved attenuation for tight junction injury on conventional Lrg1-knockout mice,as well as the inhibition effects on TGF-β1,and the phosphorylation of suppressor of mothers against decapentaplegic 2(Smad2)/Smad2 via western blot assay.Conclusion:Biochanin A could alleviate tight junction injury induced by cerebral ischemiareperfusion and blocked the Lrg1/TGF-β/Smad2 pathway to modulate leukocyte migration patterns. | LONGSHENG FU JINFANG HU FENG SHAO YAOQI WU WEI BAI MINGJIN JIANG HAO CHEN LIHUA CHEN YANNI LV | 2023 | BIOCELL2023，47，8： | 0 |
| 7 | Hydrogel-Assisted Electrokinetics for High-Resolution and Non-invasive Flow Monitoring in Microfluidic Chips显示文摘Convenient non-invasive flow monitoring would facilitate the operation and control in microfluidic chips,but is challenging due to the small space of microchannels and complex operation required in traditional optical methods.In this work,we propose a novel non-invasive strategy to probe microfluidic flows via streaming potential phenomenon.By sealing one side of the microchannel with a piece of hydrogel film,streaming potential inside the channel can be clearly detected by electrodes at outer surface of the hydrogel due to ion diffusion in the hydrogel.Flow is detected without sensors contacting with the internal liquid.Moreover,the electrodes shape like a tiny probe,which can move around mapping the flow distribution in a chip with the spatial resolution of 1 mm and flow rate detection limit of 3μL·min–1.Bubbles inside the channels can also be detected,due to the fluctuation of streaming voltage when gas-liquid interface flows through the electrode,showing an easy and potential way for multi-functional flow monitoring in microfluidic chips. | Na Zhao Yanni Ma Zehua Yu Jun Huang Xiangqian Fu Tao Qiu Kang Liu | 2024 | Chinese Journal of Chemistry2024，42，6： | 0 |
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