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| 1 | Modification of NiCoCrAlY with Pt: Part Ⅰ. Effect of Pt depositing location and cyclic oxidation performance显示文摘Pt layers of 5 μm in thickness were electroplated before or after depositing NiCoCrAlY coating by arc ion plating(AIP) aiming for identifying the effect of Pt enriching position on microstructure and cyclic oxidation behavior of Pt modified NiCoCrAlY coatings. Al-rich zones formed at the same position of Ptrich zones for both modified coatings due to uphill diffusion of Al driven by Pt. Cyclic oxidation tests at 1000 and 1100?C indicated that oxidation resistance of NiCoCrAlY was improved by Pt modification via different mechanisms: at surface, Pt-rich zone promoted selective oxidation of Al to form α-Al_2O_3,whilst at coating/substrate interface Pt-rich zone acted as effective diffusion barrier for titanium. Roles of Pt played in enhancing the oxidation performance of various Pt-modified NiCoCrAlY coating were investigated. | Yingfei Yang Hongrui Yao Zebin Bao Pan Ren Wei Li | 2019 | Journal of Materials Science & Technology2019，35，3： | 4 |
| 2 | Lysine enhances the effect of amphotericin B against Candida albicans in vitro显示文摘Amphotericin B (AmB ) 是 Streptomyces nodosus 生产的多烯抗菌素并且被用于 > 在急性全身的真菌的感染的处理的 50 年。在现在的学习,我们表明了那离氨酸,必要氨基酸,能在 vitro 对 Candida albicans 提高 AmB 的效果,尽管离氨酸本身没施加杀菌剂效果。另外,有离氨酸的 AmB 的联合能独自与 AmB 相比对 Candida parapsilosis 和 Cryptococcus neoformans 提供一个提高的行动。离氨酸能也提高 caspofungin 或制霉菌素的抗真菌的效果。有 AmB 的离氨酸的联合的提高的效果为 biofilm 和 hypha 形成的预防被观察。而且,我们的结果证明那调停离氨酸的氧化损坏例如内长的反应的氧种类的产生,可以是在 AmB 上位于离氨酸的提高的效果下面的机制。我们的结果也证明那 CaMCA1 基因在增加 C 的敏感起一个重要作用。在 AmB 处理之上的 albicans 房间。和离氨酸使用 AmB 可以是为传播 candidiasis 的治疗的有希望的策略。 | Liuya Zhao Jingchen Jiang Zhenyu Zhu Zebin Liao Xiangwen Yao Yu Yang Yingying Cao Yuanying Jiang | 2016 | Acta Biochimica et Biophysica Sinica2016，48，2： | 4 |
| 3 | Overview of bearingless induction motors显示文摘 | SUN Xiaodong CHEN Long YANG Zebin | 2014 | Mathematical Problems in Engineering2014，，1： | 1 |
| 4 | Overview ofbearingless permanent-magnet synchronous motors 显示文摘 | Sun Xiaodong Chen Long Yang Zebin | 2013 | IEEE Transactions on Industrial Electronics2013，60，12： | 1 |
| 5 | Finite-Control-Set Model Predictive Control of Permanent Magnet Synchronous Motor Drive Systems——An Overview显示文摘Permanent magnet synchronous motors(PMSMs)have been widely employed in the industry. Finite-control-set model predictive control(FCS-MPC), as an advanced control scheme, has been developed and applied to improve the performance and efficiency of the holistic PMSM drive systems. Based on the three elements of model predictive control, this paper provides an overview of the superiority of the FCS-MPC control scheme and its shortcomings in current applications. The problems of parameter mismatch, computational burden, and unfixed switching frequency are summarized. Moreover, other performance improvement schemes, such as the multi-vector application strategy, delay compensation scheme, and weight factor adjustment, are reviewed. Finally, future trends in this field is discussed, and several promising research topics are highlighted. | Teng Li Xiaodong Sun Gang Lei Zebin Yang Youguang Guo Jianguo Zhu | 2022 | IEEE/CAA Journal of Automatica Sinica2022，9，12： | 1 |
| 6 | Recent deveolpment of multifunctional responsive gas-releasing nanoplatforms for tumor therapeutic application显示文摘Gas therapy(GT)exhibits great potential for clinical application due to its high therapeutic efficiency,low systemic side effects,and biosafety,thereinto,a multifunctional nanoplatform is generally needed for controllable gas release and precise delivery to tumor tissue.In this review,the recent development of multifunctional nanoplatforms for efficient tumor delivery of stimuliresponsive gas-releasing molecules(GRMs),which could be triggered by either exogenous physical or endogenous tumor microenvironment(TME)is summarized.The reported therapeutic gas molecules,including oxygen(O_(2)),hydrogen sulfide(H_(2)S),nitric oxide(NO),hydrogen(H_(2)),and carbon monoxide(CO),etc.,could directly influence or change the pathological status.Additionally,abundant nanocarriers have been employed for gas delivery into cancer region,such as mesoporous silica nanoparticles(MSNs),metal-organic frameworks(MOFs),two-dimensional(2D)nanomaterials,and liposomes,as well as nonnanocarriers including inorganic and organic nanoparticles.In the end,the outlooks of current challenges of GT and GRMs delivery nanoplatforms as well as the prospects of future clinical applications are proposed. | Zebin Yang Hangrong Chen | 2023 | Nano Research2023，16，3： | 0 |
| 7 | Combinatorial Optimization of Physics Parameterization Schemes for Typhoon Simulation Based on a Simple Genetic Algorithm(SGA)显示文摘Each physical process in a numerical weather prediction(NWP)system may have many different parameterization schemes.Early studies have shown that the performance of different physical parameterization schemes varies with the weather situation to be simulated.Thus,it is necessary to select a suitable combination of physical parameterization schemes according to the variation of weather systems.However,it is rather difficult to identify an optimal combination among millions of possible parameterization scheme combinations.This study applied a simple genetic algorithm(SGA)to optimizing the combination of parameterization schemes in NWP models for typhoon forecasting.The feasibility of SGA was verified with the simulation of Typhoon Mujigae(2015)by using the Weather Research and Forecasting(WRF)model and Typhoon Higos(2020)by using the Coupled Ocean–Atmosphere–Wave–Sediment Transport(COAWST)modeling system.The results show that SGA can efficiently obtain the optimal combination of schemes.For Typhoon Mujigae(2015),the optimal combination can be found from the 1,304,576 possible combinations by running only 488 trials.Similar results can be obtained for Typhoon Higos(2020).Compared to the default combination proposed by the COAWST model system,the optimal combination scheme significantly improves the simulation of typhoon track and intensity.This study provides a feasible way to search for the optimal combinations of physical parameterization schemes in WRF and COAWST for more accurate typhoon simulation.This can help provide references for future development of NWP models,and for analyzing the coordination and adaptability of different physical process parameterization schemes under specific weather backgrounds. | Zebin LU Jianjun XU Zhiqiang CHEN Jinyi YANG Jeremy Cheuk-Hin LEUNG Daosheng XU Banglin ZHANG | 2024 | Journal of Meteorological Research2024，38，1： | 0 |
| 8 | Diversity of Moth Community in Wujiatang Wetland Park of Dianchi Lake显示文摘[Objective] The paper was to explore the species and dynamics of moths in Wujiatang wetland park in Dianchi lake. [Method] Moths under lamps in Wujiatang wetland park were investigated and studied regularly in 2016 and 2017, and the relationship among diversity index, indi-vidual number, species richness, evenness and diversity of moth community was analyzed. [Result] A total of 138 species of months belonging to 91 genera and 13 families were collected from Wujiatang wetland park, Dianchi lake, Kunming. The dominant insects were Crambidae and Noctuidae.The relationship between species and abundance relationship of moth community conformed to the niche priority occupation model, and the diversity index was not consistent with the evenness, but consistent with the species richness. [Conclusion]The study indicated that there were less species of moths in Wujiatang wetland park, and the community was unstable. | Liu Jiani Lu Rong Yang Yongyan Zhang Yuyu Chen Zebin Xu Shengguang Yu Lei | 2018 | Plant Diseases and Pests2018，9，3： | 0 |
| 9 | Construction of the Style of Study in Colleges and Universities in the New Period显示文摘The Nineteenth National Congress of the Communist Party of China has defined the mission of educating people for our educators.The style of study reflects the education philosophy,culture and spirit of a university from the inside to the outside. Starting from the present situation and existing problems of the construction of the style of study in colleges and universities in the new period,this paper puts forward some recommendations for the construction of the style of study in colleges and universities in the new period. | Jinzhu HUA Pengyang WU Zebin CHEN Aiping YANG Li QIN Liyuan YAO | 2018 | Asian Agricultural Research2018，10，6： | 0 |
| 10 | Effects of zero-valent iron added in the flooding or drainage process on cadmium immobilization in an acid paddy soil显示文摘Zero-valent iron(ZVI)is a promising material for the remediation of Cd-contaminated paddy soils.However,the effects of ZVI added during flooding or drainage processes on cadmium(Cd)retention remain unclear.Herein,Cd-contaminated paddy soil was incubated for 40days of flooding and then for 15 days of drainage,and the underlying mechanisms of Cd immobilization coupled with Fe/S/N redox processes were investigated.The addition of ZVI to the flooding process was more conducive to Cd immobilization.Less potential available Cd was detected by adding ZVI before flooding,which may be due to the increase in paddy soil pH and newly formed secondary Fe minerals.Moreover,the reductive dissolution of Fe minerals promoted the release of soil colloids,thereby increasing significantly the surface sites and causing Cd immobilization.Additionally,the addition of ZVI before flooding played a vital role in Cd retention after soil drainage.In contrast,the addition of ZVI in the drainage phase was not conducive to Cd retention,which might be due to the rapid decrease in soil pH that inhibited Cd adsorption and further immobilization on soil surfaces.The findings of this study demonstrated that Cd availability in paddy soil was largely reduced by adding ZVI during the flooding period and provide a novel insight into the mechanisms of ZVI remediation in Cd-contaminated paddy soils. | Hanbing Meng Shiwen Hu Zebin Hong Wenting Chi Guojun Chen Kuan Cheng QiWang Tongxu Liu Fangbai Li Kexue Liu Yang Yang | 2024 | Journal of Environmental Sciences2024，，4： | 0 |
| 11 | Master-slave synchronization of singular Lur'e systems with time-delay显示文摘This paper is concerned with the problem of designing a time-delay output feedback control law for master-slave synchronization of singular Lur'e systems. Using generalized Lyapunov stability theory, a sufficient condition for the existence of such feedback control law is given and an explicit expression of such control law is also achieved. These algorithms are formulated in terms of linear matrix inequalities, which can be easily performed numerically. A numerical example is used to illustrate the effectiveness of the design method. | Zebin YANG Xinhua ZHANG Xiaofu JI | 2011 | 控制理论与应用(英文版)2011，9，4： | 0 |
| 12 | Yangshan A-Type Granites in the Lower Yangtze River Belt Formed by Ridge Subduction:Radiogenic Ca and Nd Isotopic Constraints显示文摘The Early Cretaceous aluminous A-type granites in the Lower Yangtze River belt(LYRB)can provide important insights into the Mesozoic magmatism in eastern China,but their origin remains highly controversial.In this study,radiogenic Ca-Nd isotopic analysis was performed for syenite porphyry and alkali-feldspar granite porphyry of the Yangshan pluton,a typical aluminous A-type granitic intrusion in the LYRB,to constrain its source and geodynamic setting.The results show thatε_(Ca)(126 Ma),ε_(Nd)(126 Ma)and K/Ca_(source) of the syenite porphyry range from-0.24 to+0.96,-7.2 to-6.0,and 0.31 to 1.26,respectively.The corresponding values for the alkali-feldspar granite porphyry range from 0.26 to 0.84,-8.0 to-6.1,and 0.79 to 1.08,respectively.Binary mixing modeling indicates that they were originated from the same sources with different proportion,namely,a mixing of 50%to 75%Neoproterozoic crust and 50%to 25%asthenospheric mantle.Together with previous works,we propose that the Early Cretaceous subduction of the ridge between the Pacific and Izanagi plates was responsible for the formation of the aluminous A-type granites in the LYRB. | Jianghao Bai Mingxing Ling Xiaoyong Yang Fang Liu Huangling Gu Zebin Luo Xiaoyan Jiang Zhaofeng Zhang | 2022 | Journal of Earth Science2022，33，3： | 0 |
| 13 | The study of a highly efficient and environment-friendly scale inhibitor for calcium carbonate scale in oil fields显示文摘A highly efficient and environment-friendly scale inhibitor(MA-VA-VS)was synthesized via free radical solution polymerization method,where maleic anhydride(MA),vinyl acetate(VA)and vinyl sulfonate(VS)acted as monomers,while ammonium persulfate was used as initiator.The inhibition performance and the structure as well as properties was characterized using static jar measurement and dynamic test,Fourier transform infrared spectroscopy and thermogravimetric analysis.The surface morphology and composition of scale formed in the solution were examined using scanning electron microscopy and Xray diffraction,respectively.The binding energies of inhibitor with calcite(104)face were calculated using Materials Studio 2017(MS)at 323 K.The results show that the inhibition efficiency gradually increases with increasing inhibitor concentration.While as the Ca2þconcentration increases,the efficiency first increases and then decreases.With the increase in temperature or pH,the efficiency generally decreases.It is confirmed that the inhibition efficiency can reach 91.4%when 150 mg/L MA-VA-VS is used in a flow condition.Both the calculated binding energy and inhibition performance evaluation results demonstrate that the scale inhibition performance of MA-VA-VS is better than a commercial scale inhibitor(HPMA).The excellent inhibition performance of this inhibitor is due to its chelation and dispersion properties. | Heng Wang Junying Hu Zhi Yang Zebin Yin Qi Xiong Xiankang Zhong | 2021 | Petroleum2021，7，3： | 0 |
| 14 | Tolerance and acceptance of hepatic venous pressure gradient measurement in cirrhosis(CHESS1904):An international multicenter study显示文摘Aim:To determine the tolerance and acceptance of hepatic venous pressure gradient(HVPG)measurements in patients with liver cirrhosis.Methods:This prospective international multicenter study included 271 patients with cirrhosis who were scheduled to undergo HVPG measurement between October 2019 and June 2020.Data related to the tolerance and acceptance of HVPG measurements were collected using descriptive questionnaires.Results:HVPG measurements were technically successful in all 271 patients,with 141(52.0%)undergoing HVPG measurement alone.The complication rate was 0.4%.Postoperative pain was significantly lower than preoperative expected pain(p<0.001)and intraoperative pain(p<0.001),and intraoperative pain was also significantly lower than preoperative expected pain(p=0.036).No,mild,moderate,severe,and intolerable discomfort scores were reported by 36.9%,44.6%,11.1%,6.3%,and 0.4%of these patients,respectively,during HVPG measurement and by 54.6%32.5%,11.4%,1.5%,and 0%,respectively,after HVPG measurement.Of these patients,39.5%had little understanding and 10%had no understanding of the value of HVPG measurement,with 35.1%and 4.1%regarding HVPG measurements as being of little or no help,respectively.Most patients reported that they would definitely(15.5%),probably(46.9%),or possibly(29.9%)choose to undergo additional HVPG measurements again,and 62.7%regarded the cost of the procedure as acceptable.Conclusion:HVPG measurement was safe and well‐tolerated in patients with cirrhosis,but patient education and communication are warranted to improve the acceptance of this procedure. | Jun‐Hui Sun He Zhao Haijun Zhang Lei Li NecatiÖrmeci Zi‐Niu Yu Xun Li Shuangxi Li Xujun Yang Huaping Wei Xiaoliang Zhu Zhengcong Zhang Yajin Wang Zhongwei Zhao Jianting Mao Qiaohong Wu Xiaole Sun Huiling Xiang Kefeng Jia Chao Yang Wei Wu Xiuqing Lin Haixin Yao Changzeng Zuo Jitao Wang Bo Zhang Chunqing Zhang Xiaoling Wu Guangchuan Wang Shengjuan Yao Ruihang Wang Li Zhou Hui Huan Qingli Tu Xue Pu Feng Zhang Qin Yin Linpeng Zhang Ying Guo Jian Wang Kohei Kotani Sawako Uchida‐Kobayashi Norifumi Kawada He Zhu Li Li Wei Wang Guo Zhang Lei Yu Xudong Cui Qingliang Zhu Hailong Zhang Xiaoli Hu Rafael OXimenes Adriano Gonçalves de Araújo Giulliano Gardenghi Yubao Zheng Zebin Wu Mingsheng Huang Xiaoyong Chen Jun Wu Feng Xie Yang Bo Shengjuan Hu Linke Ma Xiao Li Xiaolong Qi | 2022 | Portal Hypertension & Cirrhosis2022，1，1： | 0 |
| 15 | Improving superficial microstructure and properties of the laser-processed ultrathin kerf in Ti-6Al-4V alloy by water-jet guiding显示文摘In the present research,the gas-assisted laser(GAL)and water-jet guided laser(WGL)processing technologies were applied to machine the ultrathin kerf in the wrought Ti-6Al-4V alloy.The microstructure,microhardness,and wear properties of the superficial layer were investigated.The results reveal that the GAL processing could machine the kerf with a high depth-to-width ratio of 12–15,but the increased processing times enhance the depth little.Due to the oxygen entrainment and relatively low heat and mass transferring efficiency,the assisted gas promotes the formation of a scaled recast layer containingβ-Ti phase and oxides,which increases the roughness to 20μm.The WGL processed kerf has a low depth-to-width ratio with a value of 1.9–2.5 and the depth could be increased by increasing the WGL processing times.With the assistance of the water jet,the remelted debris and heat could be eliminated immediately,which restrains the formation of the recast layer and heat-affected zone.The ultrathin oxide outer layer with hundreds of nanometers and ultrafineα-Ti grain inner layer are formed on the surface,which decreases the roughness to 12μm.Compared with the as-received Ti-6Al-4V alloy,the microhardness of GAL processed kerf surface is increased to 382.8 HV accompanied by residual tensile stress,while the microhardness of WGL processed kerf surface is increased to 481.6 HV accompanying with residual compressive stress.In addition,the GAL processing increases the wear rate at room temperature but decreases the wear rate at high temperatures.Comparatively,the WGL processing decreases the wear rate at room and high temperatures,simultaneously.Such wear behaviors could be ascribed to their different superficial microstructures and phase constituents. | Yang Chao Yuezhuan Liu Zifa Xu Weixin Xie Li Zhang Wentai Ouyang Haichen Wu Zebin Pan Junke Jiao Shujun Li Guangyi Zhang Wenwu Zhang Liyuan Sheng | 2023 | Journal of Materials Science & Technology2023，，25： | 0 |
| 16 | Engineering SIRPα cellular membrane-based nanovesicles for combination immunotherapy显示文摘Immune checkpoint inhibitors(ICIs)have revolutionized cancer treatment for their unprecedented clinical efficacy.Signal regulatory proteinα(SIRPα)is a phagocytic checkpoint expressed on macrophages,dendritic cells,other myeloid cells.Cancer cells inhibit macrophage phagocytosis through the interaction of the CD47-SIRPαaxis.Disrupting the CD47-SIRPαaxis has therefore been a promising strategy in restoring the immune attack against cancer.Herein,we engineered cellular membrane nanovesicles(NVs)presenting SIRPαreceptors for phagocytosis checkpoint blockade to augment the antitumor immune response.Furthermore,zebularine(Zeb),an inhibitor of DNA methyltransferase,was encapsulated into SIRPαNVs to reprogram the immunosuppressive tumor microenvironment together with blockade of phagocytosis checkpoint.It is demonstrated that SIRPα@Zeb can improve tumor immunogenicity,the polarization of tumor-associated macrophages to the M1 phenotype,increase the infiltration of CD8^(+)T lymphocytes in tumors.The robust antitumor immune response induced by SIRPα@Zeb significantly suppressed tumor growth and extended mice-bearing melanoma xenograft survival. | Mingyue Wang Yanfang Wang Yeteng Mu Fuxu Yang Zebin Yang Yuxuan Liu Lili Huang Shi Liu Xingang Guan Zhigang Xie Zhen Gu | 2023 | Nano Research2023，16，5： | 0 |
| 17 | Exosomal miR-485-3p derived from pancreatic ductal epithelial cells inhibits pancreatic cancer metastasis through targeting PAK1显示文摘Background:Cell competition is an important feature in pancreatic cancer(PC)progression,but the underlying mechanism remains elusive.This study aims to explore the role of exosomes derived from normal pancreatic ductal epithelial cells involved in PC progression.Methods:PC cells and pancreatic stellate cells(PSCs)were treated with exosomes isolated from pancreatic ductal epithelial cells.Cell proliferation was assessed by CCK8 assays.Cell migration and invasion were assessed by Transwell assays.PC and matched adjacent non-tumor tissue specimens were obtained from 46 patients pathologically diagnosed with PC at Peking University First Hospital from 2013 to 2017.Tissue miR-485-3p and p21-activated kinase-1(PAK1)expression was examined by real-time polymerase chain reaction(RT-PCR),and the relationship of the two was analyzed using Pearman’s product-moment correlation.The clinical significance of miR-485-3p was analyzed using the Chi-square test,Wilcoxon rank-sum test,and Fisher exact probability,respectively.The binding of miR-485-3p to PAK15’-untranslated region(5’-UTR)was examined by luciferase assay.PC cells were xenografted into nude mice as a PC metastasis model.Results:Exosomes from pancreatic ductal epithelial cells suppressed PC cell migration and invasion as well as the secretion and migration of PSCs.MiR-485-3p was enriched in the exosomes of pancreatic ductal epithelial cells but deficient in those of PC cells and PSCs,in accordance with the lower level in PSCs and PC cells than that in pancreatic ductal cells.And the mature miR-485-3p could be delivered into these cells by the exosomes secreted by normal pancreatic duct cells,to inhibit PC cell migration and invasion.Clinical data analysis showed that miR-485-3p was significantly decreased in PC tissues(P<0.05)and was negatively associated with lymphovascular invasion(P=0.044).As a direct target of miR-485-3p,PAK1 was found to exert an inhibitory effect on PC cells,and there was a significantly negative correlation between the expression levels of miR-485-3p and PAK1(r=-0.6525,P<0.0001)in PC tissues.Moreover,miR-485-3p could suppress PC metastasisin vivo by targeting p21-activated kinase-1.Conclusions:Exosomal miR-485-3p delivered by normal pancreatic ductal epithelial cells into PC cells inhibits PC metastasis by directly targeting PAK1.The restoration of miR-485-3p by exosomes or some other vehicle might be a novel approach for PC treatment. | Mingzhe Li Jiaxin Zhou Zhengkui Zhang Jisong Li Feng Wang Ling Ma Xiaodong Tian Zebin Mao Yinmo Yang | 2022 | Chinese Medical Journal2022，135，19： | 0 |
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