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| 1 | 医学领域一次研究和二次研究的方法学质量(偏倚风险)评价工具显示文摘方法学质量(偏倚风险)评估是医学研究开始前的重要步骤。因此,准确判断研究类型是前提,选择合适的评价工具也很重要。本综述介绍了用于随机对照试验(包括个体和整群)、动物实验、非随机干预性研究(包括随访研究、有对照组的前后对照研究、前后对照研究、非对照纵向研究、间断时间序列研究)、队列研究、病例-对照研究、横断面研究(包括分析和描述性研究)、观察性病例系列和病例报告、比较效果研究、诊断性研究、卫生经济学评价、预测研究(包括预测变量研究、预测模型影响研究、预后预测模型研究)、质性研究、结果测量工具(包括患者-报告的结果测量发展、内容真实性、结构真实性、内部一致性、跨文化真实性/测量不变性、信度、测量误差、校标真实性、结构真实性假设检验、反应度)、系统评价与Meta分析,以及临床实践指南的方法学质量评价工具。通过本综述,读者可以区分医学研究的类型并选择适当的工具。全面掌握相关知识并多加练习是正确评估方法学质量的基本要求。 | 李柄辉 訾豪 李路遥 王朝阳 任学群 郭毅(译) Ma LL Wang YY Yang ZH | 2021 | 医学新知2021，31，1： | 37 |
| 2 | TT viral infection through blood transfusion:retrospective investigation on patients in a prospective study of post-transfusion hepatitis显示文摘AIM To investigate the role of bloodtransfusion in TT viral infection(TTV).METHODS We retrospectively studied serumsamples from 192 transfusion recipients whounderwent cardiovascular surgery and bloodtransfusion between July 1991 and June 1992.Allpatients had a follow-up every other week for atleast 6 months after transfusion.Eightyrecipients received blood before screeningdonors for hepatitis C antibody(anti-HCV),and112 recipients received screened blood.Recipients with alanine aminotransferase level>2.5 times the upper normal limit were testedfor serological markers for viral hepatitis A,B,C,G,Epstein-Barr virus and cytomegalovirus.TTV infection was defined by the positivity forserum TTV DNA using the polymerase chainreaction method.RESULTS Eleven and three patients,whoreceived anti-HCV unscreened and screened'blood,respectively,had serum ALT levels>90 IU/L.Five patients(HCV and TTV:1;HCV,HGV,and TTV:1;TTV:2;and CMV and TTV:1)were positive for TTV DNA,and four of them hadsero-conversion of TTV DNA.CONCLUSION TTV can be transmitted viablood transfusion.Two recipients infected byTTV alone may be associated with the hepatitis.However,whether TTV was the causal agentremains unsettled,and further studies arenecessary to define the role of TTV infection inchronic hepatitis. | Yang SS Wu CH Chen TH Huang YY Huang CS | 2000 | World Journal of Gastroenterology2000，6，1： | 8 |
| 3 | Activation of indices of cell-mediated immunity in bipolar mania 显示文摘 | Tsai SY Chen KP Yang YY | 1999 | Biological Psychiatry1999，45，： | 1 |
| 4 | Phosphorylation of PI3K/Akt and MAPK/ERK in an early entry step of entrovirus 71 显示文摘 | Wong WR Chen YY Yang SM | 2005 | Life Sci2005，78，1： | 1 |
| 5 | Tubular epithelial-myofibroblast transdifferentiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rats显示文摘 | NG YY HUANG TP YANG WC | 1998 | Kidney Int1998，54，3： | 1 |
| 6 | Increased plasma malondialde-hyde in patients with viral cirrhosis and its relationships to plasma nitric oxide,endotoxin,and portal pressure显示文摘 | Lee KC Yang YY Wang YW | 2010 | Dig Dis Sci2010，55，7： | 1 |
| 7 | Immunologic variables in acute mania of bipolar disorders 显示文摘 | Liu HC Yang YY Chou YM | 2004 | J Neuroimmunol2004，105，： | 1 |
| 8 | Effects of vasartan with or without essential hypertention显示文摘 | Ke YS Tao YY Yang H | 2003 | Acta Pharmacol Sin2003，24，： | 1 |
| 9 | Accumulation of S-adenosyI-L-methionine enhances production of actinorhodin but inhibits sporulation in Streptomyces lividans TK23显示文摘 | Kim D J Huh JH Yang YY | 2003 | Journal of Bacteriology2003，185，2： | 1 |
| 10 | Tubular epithelial-myofibroblast transdifferentiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rats显示文摘 | Ng YY Huang TP Yang WC | 1998 | Kidney Int1998，54，： | 1 |
| 11 | Direct cholangioscopy using an uhrathin endoscope for the diagnosis of hemobilia 显示文摘 | Yen HH Yang CW Chen YY | 2014 | Dig Endosc2014，26，3： | 1 |
| 12 | Strategies employed in the de- sign and optimization of synthetic antimicrobial peptide amphiphiles with enhanced therapeutic potentials 显示文摘 | Ong ZY Wiradharma N Yang YY | 2014 | Advanced Drug Delivery Reviews2014，30，78： | 1 |
| 13 | Qualitative and quantitative analysis of triterpene saponins from tea seed pomace (Camellia oleifera Abel) and their activities against bacteria and fungi 显示文摘 | Zhang XF Yang SL Han YY | 2014 | Molecules2014，19，6： | 1 |
| 14 | In vitro and in vivo anti - inflam- matory activities of Polygonum hydropiper methanol extract 显示文摘 | Yang YY Yu T Jang HJ | 2012 | J Ethnopharmaco12012，39，2： | 1 |
| 15 | Time-dependent inhibition(TDI)of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction显示文摘 | Fang ZZ Zhang YY Ge GB Huo H Liang SC Yang L | 2010 | Br J Clin Pharmacol2010，69，2： | 1 |
| 16 | Adsorption behavior of Ni (II) on lotus stalks derived active carbon by phosphoric acid activation 显示文摘 | Huang LH Stm YY Yang T | 2011 | Desalination2011，268，13： | 1 |
| 17 | Tubular epithelial-myofibroblast transdifferentiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rats显示文摘 | Ng YY Huang TP Yang WC | 1998 | Kidney Int1998，54，3： | 1 |
| 18 | Tubular epithelial-myofibroblast transdifferntiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rat 显示文摘 | Ng YY Huang TP Yang WC | 1998 | Kidney Int1998，54，3： | 1 |
| 19 | Phosphorylation of PI3K/Akt and MAPK/ERK in an early entry step ofenterovirus 7l 显示文摘 | Wong WR Chen YY Yang SM | 2005 | Life Sci2005，78，1： | 1 |
| 20 | Role of multi-slice and threedimensional computed tomography in delineating extracardiac vascular abnormalities in neonates显示文摘 | Long YG Yang YY Huang IL | 2010 | Pediatr Neonatol2010，51，4： | 1 |
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