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| 1 | TOTAL SYNTHESIS OF CLAUSENAMIDE显示文摘TOTAL SYNTHESIS OF CLAUSENAMIDETOTALSYNTHESISOFCLAUSENAMIDE￥ErChangRAO;HaoHONG;JiaChongCHENG;GuangZhongYANG;HanSenLIN;andLian... | Er Chang RAO Hao HONG Jia Chong CHENG Guang Zhong YANG Han Sen LIN andLiang HUANG(Institute of Mareia Medica. Chinese Academy of Medical Sciences1 Xian Nong Tan St .Beijing 100050) | 1994 | Chinese Chemical Letters1994，5，4： | 4 |
| 2 | Pollinator attraction in Cornus capitata (Cornaceae): the relative role of visual and olfactory cues显示文摘Aims it is generally accepted that visual displays and floral scent play important roles in communication between flowering plants and their pollinators.However,the relative role of visual and olfactory cues in pollinator attraction is largely unknown.in this study,we determined the roles of both types of cue in attracting pollinators to Cornus capitata,a medium sized tree with each capitulum sur-rounded by four large,white,petaloid bracts.Methods Pollinator observations and pollination experiments were con-ducted in a natural population;the inflorescences’visual and olfactory signals were characterized by spectral and chemical analyses;the responses of pollinators to visual and olfactory cues were tested using dual-choice behavioural bioassays;the relative roles of visual and olfactory cues in pollinator attrac-tion were tested by comparing the responses of pollinators to inflorescences subjected to three experimental treatments(intact,all bracts removed,and capitulum removed)within the natural population.Important Findings For fruit set,C.capitata is entirely dependent on pollinators,with a bee,Anthophora sp.,being the main pollinator.bracts present high colour distance and green contrast against the leaves.Twelve volatile compounds in the floral scent were detected,most of which have previously been reported to be attractive to a broad spectrum of bee species.behavioural bioassays showed that both,visual cues alone and olfactory cues alone,are attractive to pollinating bees.However,vis-ual cues alone attracted significantly more approaches than olfactory cues alone,while olfactory cues alone elicited a significantly higher landing percentage than visual cues alone.The finding suggests that,in the C.capitata-Anthophora sp.interaction,visual cues are mainly used for location from long distances,while olfactory cues mainly aid landing from short distances.our results indicate that different modalities of floral cues should be considered together to understand fully the communication between flowering plant and pollinators. | Bo Song Yang Niu Jürg Stöcklin Gao Chen De-Li Peng Yong-Qian Gao Hang Sun | 2015 | Journal of Plant Ecology2015，8，2： | 3 |
| 3 | Noncontrast-enhanced MRI-based Noninvasive Score for Portal Hypertension(CHESS1802):An International Multicenter Study显示文摘Background and Aims:This study aimed to determine the performance of the non-invasive score using noncontrastenhanced MRI(CHESS-DIS score)for detecting portal hy-pertension in cirrhosis.Methods:In this international multicenter,diagnostic study(ClinicalTrials.gov,NCT03766880),patients with cirrhosis who had hepatic venous pressure gradient(HVPG)measurement and noncontrast-enhanced MRI were prospectively recruited from four university hospitals in China(n=4)and Turkey(n=1)between December 2018 and April 2019.A cohort of patients was retrospectively recruited from a university hospital in Italy between March 2015 and November 2017.After segmentation of the liver on fat-suppressed T1-weighted MRI maps,CHESS-DIS score was calculated automatically by an in-house developed code based on the quantification of liver surface nodularity.Results:A total of 149 patients were included,of which 124 were from four Chinese hospitals(training cohort)and 25 were from two international hospitals(validation cohort).A positive correlation between CHESS-DIS score and HVPG was found with the correlation coefficients of 0.36(p<0.0001)and 0.55(p<0.01)for the training and validation cohorts,respectively.The area under the receiver operating characteristic curve of CHESS-DIS score in detection of clinically significant portal hypertension(CSPH)was 0.81 and 0.9 in the training and validation cohorts,respectively.The intra-class correlation coefficients for assessing the inter-and intra-observer agreement were 0.846 and 0.841,respectively.Conclusions:A non-invasive score using noncontrast-enhanced MRI was developed and proved to be significantly correlated with invasive HVPG.Besides,this score could be used to detect CSPH in patients with cirrhosis. | Yanna Liu Tianyu Tang NecatiÖrmeci Yifei Huang Jitao Wang Xiaoguo Li Zhiwei Li Weimin An Dengxiang Liu Chunqing Zhang Changchun Liu Jinqiang Liu Chuan Liu Guangchuan Wang Cristina Mosconi Alberta Cappelli Antonio Bruno Seray Akçalar EmrecanÇelebioğlu EvrenÜstüner Sadık Bilgiç Zeynep Ellik ÖzgünÖmer Asiller Lei Li Haijun Zhang Ning Kang Dan Xu Ruiling He Yan Wang Yang Bu Ye Gu Shenghong Ju Rita Golfieri Xiaolong Qi | 2021 | Journal of Clinical and Translational Hepatology2021，9，6： | 3 |
| 4 | 量表评估效度的项目反应理论(英文)显示文摘项目反应理论(Item response theory,IRT)是用来评估精神病学领域那些尚未被充分使用的测量量表效度一种重要方法。IRT描述了潜在心理特征(例如,该量表拟评估心理问题的架构)、量表中各项目的属性、以及被测试者对各项目应答之间的关系。本文介绍了IRT的基本前提,假设和方法。为了帮助解释这些概念,我们依据流行病学调查中心抑郁量表修订版中三个答案为是/否二分类选项的问题制定了一个假设的量表。流行病学调查中心抑郁量表已经用于19,399被测试者。我们首先用因子分析确认这三个项目的单维性,然后用Mplus软件建立2-Parameter Logic(2-PL)IRT模型,这是一种用来评估量表中各项目两两差异和项目难度的方法。本文将就这些分析结果的临床意义和在量表结构中的用途展开讨论。 | Yang FM Kao ST | 2014 | 上海精神医学2014，26，3： | 3 |
| 5 | Changes in three types of ubiquitin mRNA and ubiquitin-protein conjugate levels during lens development 显示文摘 | Yang S Wang-Su ST Cai H | 2002 | Exp Eye Res2002，74，5： | 1 |
| 6 | Role of p53 gene mutations in human esophageal carcinogenesis: results from immunohistochemical and mutation analyses of carcinomas and nearby non-cancerous lesions 显示文摘 | Shi ST Yang GY Wang LD | 1999 | Carcinogenesis1999，20，4： | 1 |
| 7 | An optimized telomerase-speciilclentivirus for optical imaging of tumors显示文摘 | Yu ST Yang YB Liang GP | 2010 | Cancer Res2010，70，7： | 1 |
| 8 | Antibacterial and antiox- idant properties of Ramulus Cinnamomi using supercritical CO2 extraction 显示文摘 | Liang MT Yang CH Li ST | 2008 | Eur Food Res Technol2008，227，5： | 1 |
| 9 | Study of micro-electro discharge machining (micro-EDM ) with on-machine measurement-assisted tech-niques 显示文摘 | CHEN ST Yang | 2011 | Measurement Science & Technology2011，22，6： | 1 |
| 10 | The effect of product bed temperature on the microstructure of aquacoat-based controlled-release coatings 显示文摘 | Yang ST Ghebre-sellassie I | 1990 | Int J Pharm1990，60，1： | 1 |
| 11 | Engineering Propionibacterium acidipropionici for enhanced propionic acid tolerance and fermentation 显示文摘 | ZHANG A YANG ST | 2009 | Biotechnol Bioeng2009，104，4： | 1 |
| 12 | Single-incision laparoscopic versus conventional laparoscopic endorectal pull-through for Hirschsprung' s disease: A comparison of short-term surgical results 显示文摘 | Tang ST Yang Y Li SW | 2013 | J Pediatr Surg2013，48，9： | 1 |
| 13 | Antibacterial, antitumor and hemolytic activities of alpha-helical antibiotic peptide,P18 and its analogs显示文摘 | SHIN SY LEE SH YANG ST | 2001 | J Peptide Sci2001，58，6： | 1 |
| 14 | The genetics of asthma: ADAM33 as an example of a susceptibility gene显示文摘 | Holgate ST Yang Y Haitchi HM | 2006 | Proc Am Thorac Soc2006，3，5： | 1 |
| 15 | Tacrolimus for children with refractory nephrotic syndrome : a one-year prospective, muhicenter, and open-label study of Tacrobell , a generic formula 显示文摘 | Yang EM Lee ST Choi HJ | 2016 | World J Pediatr2016，12，1： | 1 |
| 16 | Host Defense Mechanisms Triggered by Microbial Lipoproteins Through Toll-Like Receptors显示文摘 | Brightbill HD Libraty DH Krutzik SR Yang RB Belisle JT Bleharski JR Maitland M Norgard MV Plevy SE Smale ST Brennan PJ Bloom BR Godowski PJ Modlin RL | 1999 | Science1999，285，5428： | 1 |
| 17 | Selective cytotoxicity following Arg-to-Lys substitution in tritrpticin adopting a unique amphipathic turn structure显示文摘 | YANG ST SHIN SY LEE CW | 2003 | FEBS Lett2003，540，13： | 1 |
| 18 | Effects of a cGMP-specific phosphodiesterase inhibitor on expression of endothelial nitric oxide synthase and vascular endothelial growth factor in rats with eyclosporine-induced nephrotoxicity 显示文摘 | Yang JW Han ST Kim YS | 2010 | Transplant Proc2010，42，10： | 1 |
| 19 | Wogonin, an active compound in Scutellaria baicalensis, induces apoptosis and reduces telomerasc aetivity in the HL-60 leukemia cells 显示文摘 | Huang ST Wang CY Yang RC | 2010 | Phytomedicine2010，17，1： | 1 |
| 20 | Laparoscopic choledochal cyst excision, hepaticojejunostomy, and extracorporeal Roux-en-Y anastomosis: a technical skill and intermediate-term report in 62 cases 显示文摘 | Tang ST Yang Y Wang Y | 2011 | Surg Endosc2011，25，2： | 1 |
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