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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | The Reference Genome of Tea Plant and Resequencing of 81 Diverse Accessions Provide Insights into Its Genome Evolution and Adaptation显示文摘Tea plant is an important economic crop,which is used to produce the world's oldest and most widely consumed tea beverages.Here,we present a high-quality reference genome assembly of the tea plant(Camellia sinensis var.sinensis)consisting of 15 pseudo-chromosomes.LTR retrotransposons(LTR-RTs)account for 70.38%of the genome,and we present evidence that LTR-RTS play critical roles in genome size expansion and the transcriptional diversification of tea plant genes through preferential insertion in promoter regions and introns.Genes,particularly those coding for terpene biosynthesis pro-teins,associated with tea aroma and stress resistance were significantly amplified through recent tandem duplications and exist as gene clusters in tea plant genome.Phylogenetic analysis of the sequences of 81 tea plant accessions with diverse origins revealed three well-differentiated tea plant populations,support-ing the proposition for the southwest origin of the Chinese cultivated tea plant and its later spread to western Asia through introduction.Domestication and modern breeding left significant signatures on hundreds of genes in the tea plant genome,particularly those associated with tea quality and stress resis-tance.The genomic sequences of the reported reference and resequenced tea plant accessions provide valuable resources for future functional genomics study and molecular breeding of improved cul-tivars of tea plants. | Enhua Xia Wei Tong Yan Hou Yanlin An Linbo Chen Qiong Wu Yunlong Liu Jie Yu Fangdong Li Ruopei Li Penghui Li Huijuan Zhao Ruoheng Ge Jin Huang Ali Inayat Mallano Yanrui Zhang Shengrui Liu Weiwei Deng Chuankui Song Zhaoliang Zhang Jian Zhao Shu Wei Zhengzhu Zhang Tao Xia Chaoling Wei Xiaochun Wan | 2020 | Molecular Plant2020，13，7： | 51 |
| 3 | Qi-Qin Accretionary Belt in Central China Orogen: accretion by trench jam of oceanic plateau and formation of intra-oceanic arc in the Early Paleozoic Qin-Qi-Kun Ocean显示文摘Most orogenic belts have experienced a complex accretionary process with multiple episodes of sea?oor subduction and trench retreat.This accretionary process is important in continenta development and growth[1,2].Three giant orogens extend in China,e.g.,the Central Asian Orogen in the north,the Central China Orogen in the middle and the Himalayan Orogen in the southwest.They are keys for the formation of the Eurasian continent(Fig.1a).The Central China Orogen | Shuguang Song Liming Yang Yuqi Zhang Yaoling Niu Chao Wang Li Su Yanlin Gao | 2017 | Science Bulletin2017，62，15： | 28 |
| 4 | Thermodynamics and kinetics of phase transformation in rare earth–magnesium alloys:A critical review显示文摘Magnesium and its alloys are significant superior metallic materials for structural components in automobile and aerospace industries due to their excellent physicomechanical properties.The Mg–rare earth(RE)systems have attracted great interests because RE additions can improve both the deformability and the strength of Mg alloys through solid solution strengthening and precipitation hardening mechanisms.This paper focuses on the interface stability,together with thermodynamics and kinetics of nucleation and growth of the key phases and matrix phases in Mg–RE alloys.In this paper,the theory and recent advances on Mg–RE alloys,especially for the interface stability,thermodynamics and kinetics of nucleation and growth of the key phases and matrix phases,together with their relationships with micro-structures,and macroscopic properties,are reviewed.By combining the thermodynamics/kinetics integrated simulations with various advanced experimental techniques,“reverse”design of Mg–RE alloys starting from the target service performance is put forward as a kind of scientific paradigm with rational design. | Qun Luo Yanlin Guo Bin Liu Yujun Feng Jieyu Zhang Qian Li Kuochih Chou | 2020 | Journal of Materials Science & Technology2020，44，9： | 26 |
| 5 | A distributed scheme developed for eco-hydrological modeling in the upper Heihe River显示文摘Modeling the hydrological processes at catchment scale requires a flexible distributed scheme to represent the catchment topography,river network and vegetation pattern.This study has developed a distributed scheme for eco-hydrological simulation in the upper Heihe River.Based on a 1 km×1 km grid system,the study catchment is divided into 461 sub-catchments,whose main streams form the streamflow pathway.Furthermore,a 1 km grid is represented by a number of topographically similar'hillslope-valley'systems,and the hillslope is the basic unit of the eco-hydrological simulation.This model is tested with a simplified hydrological simulation focusing on soil-water dynamics and streamflow routing.Based on a 12-year simulation from 2001 to 2012,it is found that variability in hydrological behavior is closely associated with climatic and landscape conditions especially vegetation types.The subsurface and groundwater flows dominate the total river runoff.This implies that the soil freezing and thawing process would significantly influence the runoff generation in the upper Heihe basin.Furthermore,the runoff components and water balance characteristics vary among different vegetation types,showing the importance of coupling the vegetation pattern into catchment hydrological simulation.This paper also discusses the model improvement to be done in future study. | YANG DaWen GAO Bing JIAO Yang LEI Hui Min ZHANG YanLin YANG HanBo CONG ZhenTao | 2015 | Science China Earth Sciences2015，58，1： | 20 |
| 6 | Autophagy in Atherosclerosis: A Phenomenon Found in Human Carotid Atherosclerotic Plaques显示文摘 | Huihui Liu Yongjun Gag Tong Tong Jijun Shi Yanlin Zhang Yaping Yang Chunfeng Liu | 2015 | Chinese Medical Journal2015，，1： | 16 |
| 7 | Earthquake-induced soft-sediment deformation structures in the Mesoproterozoic Wumishan Formation,North China,and their geologic implications显示文摘Soft-sediment structures are key to defining seismites. Two soft-sediment deformation horizons, bounded by undeformed carbonate strata, have been found in the Wumishan Formation in the Jumahe region, 175 km southwest of Beijing. One is in the lowest part of Wumishan Formation; and the other is in the uppermost part of Litho-member I. The soft-sediment structures in these two horizons fall into three categories: mould-and-sag structures, hydraulic shatterings and liquefaction dikes. The mould-and-sag structures are divided into two types: one developed in tidal-flat sediments, accompa-nied by many liquefaction-related structures and characterized by autochthonous post-earthquake sediments in sags, and the other type developed in deep-water environments, is not associated with liquefaction structures, and is overlain immediately by seismogenic tsunamites. The hydraulic shat-terings are composed of pockets of fluidization conglomerate, sand intrusions, and syndepositional faults. The liquefaction dikes fall into two categories: hydraulic-fracturing dikes and lateral-spreading dikes. The former are steep, planar, and pinch out upwards. The latter are snake-like and characterized by no diapir-related drag structures in surrounding rocks. Examination of the attitudes and strati-graphic positions of these structures suggests that these soft-sediment structures are seismogenic, and consequently, are seismites. Most seismites in the Wumishan Formation are developed near the former western, margin fault of Yanliao rift. This occurrence suggests that they could be related to movements on this fault. Other geological implications are discussed. | ZHANG ChuanHeng WU ZhengJie GAO LinZhi WANG Wei TIAN YanLin MA Chao | 2007 | Science China Earth Sciences2007，50，3： | 15 |
| 8 | Characteristics and Morbidity of the Tuberculosis Epidemic--China,2019显示文摘Introduction:The year 2019 was crucial for the implementation of China’s National“13th 5-Year”Tuberculosis(TB)Control Plan.We conducted this study to evaluate the characteristics and progress towards controlling TB in China.Methods:We collected and analyzed the pulmonary tuberculosis(PTB)data of China between January 1,2015 and December 31,2019 from the National Notifiable Disease Reporting System(NNDRS).Results:In 2019,there were 775,764 PTB cases reported in NNDRS,of which 349,307 were bacteriologically-confirmed(Bac+)cases.The PTB case notification rate(CNR)was 55.55 per 100,000,and the Bac+CNR was 25.01 per 100,000.From 2018 to 2019,the number of PTB cases fell by 6.3%,but the number of Bac+cases increased by 25.9%.The annual decrease in the rate of reported PTB was 3.4% from 2015 to 2019.The 5 provincial-level administrative divisions(PLADs)with the highest PTB CNR were as follows:Tibet(182.38 per 100,000),Xinjiang(169.05 per 100,000),Qinghai(134.53 per 100,000),Guizhou(102.51 per 100,000),and Hainan(90.22 per 100,000).The rate of reported PTB was 74.84 per 100,000 for males and 35.40 per 100,000 for females.There were 8,116 cases(1.0%)among children aged 0–14 years,and 197,730 cases(25.5%)among adults aged 65 years and over.Of the reported cases,470,932 were farmers,which was the most common occupation at 60.7%.Conclusions and Implications for Public Health Practice:The TB epidemic has decreased dramatically year by year.Most PTB cases were in the central and western regions of China,and the high-risk groups were farmers and elderly people aged 65 years and over. | Wei Chen Hui Zhang Xin Du Tao Li Yanlin Zhao | 2020 | China CDC weekly2020，2，12： | 13 |
| 9 | The Epidemiological Characteristics of Pulmonary Tuberculosis——Kashgar Prefecture,Xinjiang Uygur Autonomous Region,China,2011-2020显示文摘Introduction:National Notifiable Disease Reporting System(NNDRS)plays an important role in the early detection and control of tuberculosis(TB)in China.This study analyzed the epidemiological characteristics of pulmonary tuberculosis(PTB)in Kashgar Prefecture,Xinjiang Uygur Autnomous Region,China from 2011 to 2020 to provide a scientific basis for developing TB control strategies and measures in Kashgar.Methods:The data were collected from the NNDRS,which included the geographical distribution,age,sex,occupation,and pathogenic classification of reported PTB cases in 12 counties/cities of Kashgar Prefecture from 2011 to 2020.Descriptive statistics were used to describe the characteristic of PTB epidemic in Kashgar.Results:There were 189,416 PTB cases reported during 2011–2020,with a mean annual PTB case notification rate(CNR)of 451.29/100,000.A rising trend in the rate of reported PTB between 2011 and 2017(χ2 trend=26.09,P<0.01)and a declining trend between 2018 and 2020(χ2 trend=314.44,P<0.01)were observed.The months with the highest reported number of PTB cases were March to May and November to December.The mean annual rate of reported PTB was 451.88/100,000 for males and 450.67/100,000 for females.In addition,19.76%of patients were bacteriologically-confirmed(Bac+)cases(37,425/189,416),and the mean annual Bac+CNR was 89.17/100,000,rising from 64.76/100,000 in 2011 to 139.12/100,000 in 2020(χ^(2)_(trend)=74.44,P<0.01).Conclusions:The CNR of reported PTB in Kashgar showed a significant declining trend in the past three years.Males,elderly population,winter and spring,and farmers as an occupation were the main factors associated with high incidence of tuberculosis in Kashgar.Targeted prevention and treatment of TB should be strengthened in key groups in this region. | Diermulati Tusun Maiweilanjiang Abulimiti Xirizhati Mamuti Zhenjiang Liu Da Xu Guanzhen Li Xiaowang Peng Tuerhong Abudureyimu Lijie Zhang Yanlin Zhao Xichao Ou | 2021 | China CDC weekly2021，3，26： | 6 |
| 10 | Technology for high performance TRIP steel显示文摘Thermodynamics of martensite transformation in low alloy TRIP steel was evaluated.It follows from the calculation that ε phase might be formed at above room temperature in the low Mn steel.Tested steel was therefore prepared according to the estimation result.High volume fraction of retained austenite(above 20%) containing 1.37%C was obtained in the steel after continuous annealing treatment.Tensile test showed that the ultimate strength of the steel was 1248 MPa,elongation rate 25%,the product of strength and elongation rate 31200 MPa%,reaching the grade of the third generation automobile steel.XRD detection indicated that after tensile test there existed ' martensite while TEM revealed that ε martensite also existed in the steel.Strengthening-toughening of the steel was thus raised due to the effect of transformation induced plasticity of two kinds of martensite.In addition,the phase stability of carbonitrates containing V was estimated and the complex micro-alloying effect was applied to the steel to control the size of austenite(about 1 μm) and enhance the stability of austenite. | LI Lin GAO Yi ZHU NaQiong HE YanLin LIU RenDong HE ZhongPing SHI Wen ZHANG Mei | 2012 | Science China(Technological Sciences)2012，55，7： | 5 |
| 11 | Prevalence of Metabolic Syndrome and Risk Factors Among Chinese Adults:Results from a Population-Based Study—Beijing,China,2017–2018显示文摘Summary What is already known about this topic?Metabolic syndrome(MetS)is one of the most easily available health indicative markers for cardiovascular diseases,and it has become a major public health problem worldwide due to increasing urbanization and aging populations.The prevalence of MetS increased dramatically in China,however,there are no records of MetS defined by the 2017 Chinese Diabetes Society for Beijing by far.What is added by this report?In this study,the data of 24,412 participants aged 18–74 years from a large population-based study in Beijing was collected.The overall prevalence of MetS among Beijing residents was 24.5%.The prevalence was 35.2%in males and 15.4%in females.What are the implications for public health practice?Effective public health strategies should target males,people with older age,lower education,higher body mass index,smokers,those who drink alcohol,those who are unemployed or retired,and those who live in rural areas on MetS prevention and control. | Jufen Liu Qingping Liu Zhiwen Li Jing Du Chao Wang Yanlin Gao Zaihua Wei Jing Wang Yunping Shi Jianting Su Yang Liu Ping Wang Chunyan Xie Gang Li Bing Shao Le Zhang | 2022 | China CDC weekly2022，4，29： | 4 |
| 12 | Polydopamine and ammonium bicarbonate coated and doxorubicin loaded hollow cerium oxide nanoparticles for synergistic tumor therapy显示文摘The development of effective nanoplatforms is extremely necessary for cancer therapy.Herein,we prepared polydopamine(PDA)andammonium bicarbonate(NH4HCO3)coated and doxorubicin(Dox)loaded hollow cerium oxide(CeO2)NPs(PDAC NPs),which showedexcellent synergistic effect for photothermal therapy,chemotherapy and chemodynamic therapy.Under near infrared laser irradiation,PDA shell could absorb the incident light and convert it into heat,which could not only kill tumor cells with hyperthermia,but also trigger thedecomposition of NH4HCO3 into gaseous carbon dioxide and ammonia,leading to the destroy of PDA shell.The leakage of PDA furtheraccelerated Dox release and exposed CeO2 surface,in which Dox could enter into cell nucleus to induce chemotherapy,and CeO2 couldcatalyze cellular hydrogen peroxide into hydroxyl radical to present chemodynamic therapy.In fact,PDAC NPs showed an excellenttherapeutic efficacy both in vitro and in vivo.This design provides a new strategy for synergistic tumor therapy. | Keqiang Xu Yan Cheng Jiao Yan Yanlin Feng Runxiao Zheng Xiaqhig Wu Yanjing Wang Panpan Song Haiyuan Zhang | 2019 | Nano Research2019，12，12： | 4 |
| 13 | Effect of Mesoscale Land Use Change on Characteristics of Convective Boundary Layer:Semi-Idealized Large Eddy Simulations over Northwest China显示文摘Although large-scale topography and land use have been properly considered in weather and climate models, the effect of mesoscale and microscale heterogeneous land use on convective boundary layer(CBL) has not been fully understood yet. In this study, the influence of semi-idealized strip-like patches of oases and deserts, which resemble irrigated land use in Northwest China, on the CBL characteristics, is investigated based on the Weather Research and Forecasting(WRF)-large eddy simulation(LES) driven by observed land surface data. The influences of soil water content in oases on aloft CBL flow structure, stability, turbulent kinetic energy(TKE), and vertical fluxes are carefully examined through a group of sensitivity experiments. The results show that secondary circulation(SC)/turbulent organized structures(TOS) is the strongest/weakest when soil water content in oases is close to saturation(e.g.,when the oases are irrigated). With the decrease of soil water content in oases(i.e., after irrigation), SC(TOS) becomes weak(strong) in the lower and middle CBL, the flux induced by SC and TOS becomes small(large), which has a dramatic impact on point measurement of eddy covariance(EC) fluxes. The flux induced by SC and TOS has little influence on EC sensible heat flux, but great influence on EC latent heat flux. Under this circumstance, the area averaged heat flux cannot be represented by point measurement of flux by the EC method, especially just after irrigation in oases. Comparison of imbalance ratio(i.e., contribution of SC and TOS to the total flux) reveals that increased soil moisture in oases leads to a larger imbalance ratio as well as enhanced surface heterogeneity. Moreover,we found that the soil layer configuration at different depths has a negligible impact on the CBL flux properties. | Bangjun CAO Shuwen ZHANG Deqin LI Yanlin LI Linfan ZHOU Jiemin WANG | 2018 | Journal of Meteorological Research2018，32，3： | 4 |
| 14 | Phenolic Composition Analysis and Gene Expression in Developing Seeds of Yellow-and Black-seeded Brassica napus显示文摘Breeders have focused on yellow-seeded Brassica napus (rapeseed) for its better quality com- pared with the black-seeded variety. Moreover, flavonoids have been associated with this kind of rapeseed. In this study, we applied lipid chromatography-electrospray ionization mass spec- trometry (LC-ESI-MSn ) to compare flavonoids in developing seeds of natural black-seeded B. na- pus and yellow-seeded introgression lines selected from progenies of B. napus-Sinapis alba so- matic hybrids. Aside from the most abundant phenolic compounds (sinapine and sinapic acid) and 1, 2-disinapoylglucose, 16 different flavonoids were identified and quantified, including (-)- epicatechin, five monocharged oligomers of (-)-epicatechin ([DP 2]- , [DP 3]- , [DP 4] [DP 2]- B2 and [DP 2]- B5), quercetin, kaempferol, isorhamnetin-dihexoside, kaempferol-sinapoyl-trihexoside, isorhamnetin- sinapoyl-trihexoside, isorhamnetin-hexoside-sulfate, and isorhamnetin-3-O-glucoside. Most of the flavonoids accumulated with seed development, whereas some rapidly decreased during maturation. The content of these flavonoids was lower in the yellow-seeded materials than in the black seeds. In addition, variations of insoluble procyanidin oligomers and soluble phenolic acids were observed among both rapeseed varieties. Transcriptome changes of genes participating in the flavonoid pathway were discovered by quantitative reverse transcription polymerase chain reaction analysis. Consistent with flavonoid changes identified by high performance liquid chromatography analysis, the expression of most genes in the flavonoid biosynthetic pathway was also downregulated. | Jinjin Jiang Yanlin Shao Aimin Li Chunliang Lu Yongtai Zhang Youping Wang | 2013 | Journal of Integrative Plant Biology2013，55，6： | 4 |
| 15 | Underreporting of Notifiable Pulmonary Tuberculosis Cases to the National Tuberculosis Information Management System--China,2015显示文摘What is already known about this topic?Tuberculosis(TB)notification data and the underreporting rate are major sources used in estimating TB incidence.China’s TB Information Management System(TBIMS)was launched in 2005 but has not yet been evaluated for sensitivity.What is added by this report?The average underreporting rate of pulmonary TB to TBIMS in selected facilities was 8.23%.However,provincial TB or infectious disease-specific health facilities,or general health facilities had higher underreporting rates.Children,migrants,and drug resistant TB patients had higher chances to be underreported than other populations.What are the implications for public health practice?Underreporting surveys should be routinely implemented in the future.This will be vital for enhancing TB reporting and the transfer mechanisms in TB or infectious disease-specific hospitals,or general hospitals and improving the case information registration procedures in designated health facilities(DHFs). | Tao Li Wei Chen Yanlin Zhao Lixia Wang Mingting Chen Xin Du Hui Zhang | 2020 | China CDC weekly2020，2，12： | 4 |
| 16 | Multichannel Financing Reduces Economic Burden and Improves the Medical Security Level for Tuberculosis Patients显示文摘Tuberculosis(TB)is one of the main infectious diseases to simultaneously cause poverty and be caused by poverty.Reducing the economic burden of TB patients in China is essential to improving patient compliance and reducing the impact of the TB epidemic.In accordance with the national reform of the medical and health system and the current status of the country’s TB prevention and treatment service system,representatives of the government proposed the concept of a multichannel financing mechanism. | Fei Huang Ni Wang You Li Hui Zhang Yanli Yuan Xiaomeng Wang Xiaolin Wang Shitong Huan Lixia Wang Mingting Chen Yanlin Zhao | 2020 | China CDC weekly2020，2，12： | 3 |
| 17 | δ^(15)N-stable isotope analysis of NH_(x): An overview on analytical measurements, source sampling and its source apportionment显示文摘Agricultural sources and non-agricultural emissions contribute to gaseous ammonia(NH_(3))that plays a vital role in severe haze formation.Qualitative and quantitative contributions of these sources to ambient PM_(2.5)(particulate matter with an aerodynamic equivalent diameter below 2.5µm)concentrations remains uncertain.Stable nitrogen isotopic composition(δ^(15)N)of NH_(3)and NH_(4)+(δ^(15)N(NH_(3))andδ^(15)N(NH_(4)+),respectively)can yield valuable information about its sources and associated processes.This review provides an overview of the recent progress in analytical techniques forδ^(15)N(NH_(3))andδ^(15)N(NH_(4)+)measurement,sampling of atmospheric NH_(3)and NH_(4)+in the ambient air and their sources signature(e.g.,agricultural vs.fossil fuel),and isotope-based source apportionment of NH_(3)in urban atmosphere.This study highlights that collecting sample that are fully representative of emission sources remains a challenge in fingerprintingδ^(15)N(NH_(3))values of NH_(3)emission sources.Furthermore,isotopic fractionation during NH_(3)gas-to-particle conversion under varying ambient field conditions(e.g.,relative humidity,particle pH,temperature)remains unclear,which indicates more field and laboratory studies to validate theoretically predicted isotopic fractionation are required.Thus,this study concludes that lack of refinedδ^(15)N(NH_(3))fingerprints and full understanding of isotopic fractionation during aerosol formation in a laboratory and field conditions is a limitation for isotope-based source apportionment of NH_(3).More experimental work(in chamber studies)and theoretical estimations in combinations of field verification are necessary in characterizing isotopic fractionation under various environmental and atmospheric neutralization conditions,which would help to better interpret isotopic data and our understanding on NH_(x)(NH_(3)+NH_(4)+)dynamics in the atmosphere. | Noshan Bhattarai Shuxiao Wang Yuepeng Pan Qingcheng Xu Yanlin Zhang Yunhua Chang Yunting Fang | 2021 | Frontiers of Environmental Science & Engineering2021，15，6： | 3 |
| 18 | Study of deformation and aging behaviors of a hot rolled–quenched Cu–Cr–Zr–Mg–Si alloy during thermomechanical treatments显示文摘 | Chengdong Xia Yanlin Jia Wan Zhang Ke Zhang Qiyi Dong Genying Xu Mingpu Wang | 2012 | Materials and Design2012，，： | 3 |
| 19 | Strain heterogeneity,cooccurrence network,taxonomic composition and functional profile of the healthy ocular surface microbiome显示文摘Background:There is growing evidence indicating that the microbial communities that dwell on the human ocular surface are crucially important for ocular surface health and disease.Little is known about interspecies interactions,functional profiles,and strain heterogeneity across individuals in healthy ocular surface microbiomes.Methods:To comprehensively characterize the strain heterogeneity,cooccurrence network,taxonomic composition and functional profile of the healthy ocular surface microbiome,we performed shotgun metagenomics sequencing on ocular surface mucosal membrane swabs of 17 healthy volunteers.Results:The healthy ocular surface microbiome was classified into 12 phyla,70 genera,and 140 species.The number of species in each healthy ocular surface microbiome ranged from 6 to 47,indicating differences in microbial diversity among individuals.The species with high relative abundances and high positivity rates were Streptococcus pyogenes,Staphylococcus epidermidis,Propionibacterium acnes,Corynebacterium accolens,and Enhydrobacter aerosaccus.A correlation network analysis revealed a competitive interaction of Staphylococcus epidermidis with Streptococcus pyogenes in ocular surface microbial ecosystems.Staphylococcus epidermidis and Streptococcus pyogenes revealed phylogenetic diversity among different individuals.At the functional level,the pathways related to transcription were the most abundant.We also found that there were abundant lipid and amino acid metabolism pathways in the healthy ocular surface microbiome.Conclusion:This study explored the strain heterogeneity,cooccurrence network,taxonomic composition,and functional profile of the healthy ocular surface microbiome.These findings have important significance for the future development of probiotic-based eye therapeutic drugs. | Yutong Kang Shudan Lin Xueli Ma Yanlin Che Yiju Chen Tian Wan Die Zhang Jiao Shao Jie Xu Yi Xu Yongliang Lou Meiqin Zheng | 2021 | Eye and Vision2021，8，1： | 3 |
| 20 | Geological controls of shale gas accumulation and enrichment mechanism in Lower Cambrian Niutitang Formation of western Hubei, Middle Yangtze, China显示文摘The lower Cambrian Niutitang Formation is of crucial importance for shale gas target reservoirs in western Hubei,China;however,little work has been done in this field,and its shale gas accumulation and enrichment mechanism are still unclear.Based on survey wells,outcrop data,and large numbers of tests,the geological conditions of shale gas accumulation were studied;moreover,the factors that influence the gas content were thoroughly discussed.The results show that the Niutitang Formation(Є1n)can be divided into three sections:the first section(Є_(1)n^(1)),the second section(Є_(1)n^(2)),and the third section(Є1n3).TheЄ_(1)n^(2) is the main shale gas reservoir.The deep shelf facies is the main sedimentary facies and can be divided into three main lithofacies:argillaceous siltstone,carbonaceous shale and carbonaceous siliceous rock.The total organic carbon(TOC)content shows gentle growth trends until bottom of theЄ_(1)n^(2) and then decreases rapidly within theЄ_(1)n^(1),and the TOC content mainly ranges from 2%to 4%horizontally.The calcite and dolomite dissolution pores,clay intergranular pores and organic pores are the main pore types and the micropore types are clearly related to the mineral compositions and the TOC content.Vertically,the gas content is mainly affected by the TOC content.Horizontally,wells with high gas contents are distributed only southeast of the Huangling anticline,and the combination of structural styles,fault and fracture development,and the distribution of the regional unconformity boundary between the upper Sinian Dengying Formation(Z2d)and theЄ_(1)n^(2) are the three most important factors affecting the gas content.The favorable areas must meet the following conditions:a deep shelf environment,the presence of theЄ_(1)n^(1),wide and gentle folds,far from large normal faults that are more than 5 km,moderate thermal evolution,and greater than 500 m burial depth;this includes the block with the YD2–ZD2 wells,and the block with the Y1 and YD4 wells,which are distributed in the southern portion of the Huangling anticline and northern portion of the Xiannvshan fault. | Lulu XU Saipeng HUANG Zaoxue LIU Yaru WEN Xianghui ZHOU Yanlin ZHANG Xiongwei LI Deng WANG Fan LUO Cheng CHEN | 2021 | Frontiers of Earth Science2021，15，2： | 3 |
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