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| 1 | Volatile Organic Compounds and Their Roles in Bacteriostasis in Five Conifer Species显示文摘In order to make clear the functions of plant volatile organic compounds (VOCs) on bacteriostasis and air decontamination, we analyzed the composition and content of VOCs in Pinus tabulaeformis Carr., P. bungeana Zucc., Sabina chinensis Antoine, Picea koraiensis Nakai, and Cedrus deodara G. Don under near-natural conditions using the thermal-desorption cold trap gas chromatography/mass spectrometer technique. The effects of the VOCs on airborne microorganisms were investigated using the method of natural sedimentation. Results showed that the major VOCs were as follows: limonene, β-pinene, α-pinene,and α-caryophyllene in Pinus tabulaeformis and P. bungeana; limonene, borneol acetate, β-pinene, myrcene,and tricylene in S. chinensis; limonene, α-pinene, myrcene, camphene, and β-pinene in Picea koraiensis;and limonene, 2, (10)-pinene, α-pinene, and myrcene in C. deodara. These VOCs and the corresponding foliar extracts inhibited the growth of bacteria and stimulated the growth of fungi. Experimental data using monomers of the VOCs demonstrated that limonene, β-pinene, and three aldehydes could significantly inhibit bacterial growth, suggesting an inhibitory effect of VOCs on the growth of airborne microorganisms in the five conifer species. The bacteriostasis and air-decontaminating effects of plant VOCs are further discussed in terms of their chemical composition. | YanGAO You-JuJIN Hai-DongLI Hua-JunCHEN | 2005 | Journal of Integrative Plant Biology2005，47，4： | 52 |
| 2 | Association of interleukin-12 p40 gene 3'-untranslated region polymorphism and outcome of HCV infection显示文摘AIM: To investigate the effect of interleukin-12 p40 gene (IL12E 3'-untranslated region polymorphism on the outcome of HCV infection.METHODS: A total of 133 patients who had been infected with HCV for 12-25 (18.2±3.8) years, were enrolled in this study. Liver biochemical tests were performed with an automated analyzer and HCV RNA was detected by fluorogenic quantitative polymerase chain reaction. B-mode ultrasound was used for liver examination. Polymerase chain reactionrestriction fragment length polymorphism (PCR-RFLP) was used for the detection of IL12B (1188A/C) polymorphism.RESULTS: Self-limited infection was associated with AC genotype (OR = 3.48; P = 0.001) and persistent infection was associated with AA genotype (OR = 0.34; P = 0.014)at site 1188 of IL12B. In patients with persistent HCV infection, no significant differences were found regarding the age, gender, duration of infection and biochemical characteristics (P>0.05). According to B-mode ultrasound imaging and clinical diagnosis, patients with persistent infection were divided into groups based on the severity of infection. No significant differences were found in the frequency of IL-12 genotype (1188A/C) between different groups (P>0.05).CONCLUSION: The polymorphism of II12B (1188A/C)appears to have some influence on the outcome of HCV infection. | Li-MinYin Wan-FuZhu LaiWei Xiao-YuanXu De-GuiSun Yan-BinWang Wen-MeiFan MinYu Xiu-LanTian Qi-xinwang YanGao HuiZhuang | 2004 | World Journal of Gastroenterology2004，10，16： | 7 |
| 3 | Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in treatment of gastric cancer with peritoneal carcinomatosis显示文摘Although gastric cancer with peritoneal carcinomatosis is associated with poor prognosis and is generally treated with palliative systemic therapy, recent studies have shown that cytoreductive surgery(CRS) and hyperthermic intraperitoneal chemotherapy(HIPEC) may prove to be an efficacious treatment option. In addition to reviewing the natural history of gastric cancer with peritoneal carcinomatosis, this mini-review examines literature on the efficacy of CRS and HIPEC as compared to chemotherapy and surgical options. Both randomized and nonrandomized studies were summarized with the emphasis focused on overall survival. In summary, CRS and HIPEC are indeed a promising treatment option for gastric cancer with peritoneal carcinomatosis and large randomized clinical trials are warranted. | Lynne M.Ellison Yangao Man Alexander Stojadinovic Hongwu Xin Itzhak Avital | 2017 | Chinese Journal of Cancer Research2017，29，1： | 5 |
| 4 | Somatic mutation analysis of p53 and ST7 tumor suppressor genes in gastric carcinoma by DHPLC显示文摘AIM: To verify the effectiveness of denaturing highperformance liquid chromatography (DHPLC) in detecting somatic mutation of p53 gene in gastric carcinoma tissues.The superiority of this method has been proved in the detection of germline mutations, but it was not very affirmative with respect to somatic mutations in tumor specimens. ST7 gene, a candidate tumor suppressor gene identified recently at human chromosome 7q31.1, was also detected because LOH at this site has also been widely reported in stomach cancer.METHODS: DNA was extracted from 39 cases of surgical gastric carcinoma specimen and their correspondent normal mucosa. Seven fragments spanning the 11 exons were used to detect the mutation of p53 gene and the four exons reported to have mutations in ST7 gene were amplified by PCR and directly analyzed by DHPLC without mixing with wild-type allele.RESULTS: In the analysis of p53 gene mutation, 9 aberrant DHPLC chromatographies were found in tumor tissues, while their normal-adjacent counterparts running in parallel showed a normal shape. Subsequent sequencing revealed nine sequence variations, 1 polymorphism and 8 mutations including 3 mutations not reported before. The mutation rate of p53 gene (21%) was consistent with that previously reported. Furthermore, no additional aberrant chromatography was found when wild-type DNA was added into the DNA of other 30 tumor samples that showed normal shapes previously. The positivity of p53 mutations was significantly higher in intestinal-type carcinomas (40 %) than that in diffuse-type (8.33 %) carcinomas of the stomach. No mutation of ST7 gene was found.CONCLUSION: DHPLC is a very convenient method for the detection of somatic mutations in gastric carcinoma. The amount of wild type alleles supplied by the non-tumorous cells in gastric tumor specimens is enough to form heteroduplex with mutant alleles for DHPLC detection. ST7 gene may not be the target gene of inactivation at 7q31 site in gastric carcinoma. | ChongLu Hui-MianXu QunRen YangAo Zhen-NingWang XueAo LiJiang YangLuo XueZhang | 2003 | World Journal of Gastroenterology2003，9，12： | 4 |
| 5 | The activity of recombinant human neuroglobin as an antioxidant and free radical scavenger显示文摘 | WeiguangLi YonghongWu ChanghongRen YimingLu YanGao XiaofeiZheng ChenggangZhang | | Proteins0，，： | 1 |
| 6 | Why not greater catch-up by Chinese firms? The impact of IPR, corporate governance and technology intensity on late-comer strategies显示文摘 | Yangao Xiao Andrew Tylecote Jiajia Liu | 2012 | Research Policy2012，，： | 1 |
| 7 | The activity of recombinant human neuroglobin as an antioxidant and free radical scavenger显示文摘 | WeiguangLi YonghongWu ChanghongRen YimingLu YanGao XiaofeiZheng ChenggangZhang | 2010 | Proteins2010，，1： | 1 |
| 8 | Synergistic action of exogenous salicylic acid and arbuscular mycorrhizal fungus colonization in Avena nuda seedlings in response to NO2 exposure显示文摘 | LI Runguo JIANG Yangao XU Jia | 2010 | Bull Environ Contam Toxicol2010，84，： | 1 |
| 9 | Video Composition by Optimized 3d Mean-Value Coordinates 显示文摘 | Yang Shen Xiao Lin YanGao | 2012 | Computer Animation and Virtual Worlds (S1546-427X)2012，23，34： | 1 |
| 10 | The activity of recombinant human neuroglobin as an antioxidant and free radical scavenger显示文摘 | WeiguangLi YonghongWu ChanghongRen YimingLu YanGao XiaofeiZheng ChenggangZhang | 2010 | Proteins2010，，1： | 1 |
| 11 | The I‐antigens of Ichthyophthirius multifiliis are GPI‐Anchored Proteins显示文摘 | THEODORE G.CLARK YANGAO JACEKGAERTIG XUTINGWANG GEORGINACHENG | 2005 | Journal of Eukaryotic Microbiology2005，，3： | 1 |
| 12 | Flexural Wave Propagation in Single-walled Carbon Nanotubes显示文摘 | Liew KM Yangao Hu He XQ | 2008 | Journal of Computational and TheoreticalNanoscience2008，5，4： | 1 |
| 13 | Cryo-EM structure of Type Ⅲ-A CRISPR effector complex显示文摘Dear Editor,In bacteria and archaea,Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-associated (Cas) proteins constitute a crRNA-guided surveillance complex that defends against invading nucleic elements.^1 The CRISPR-Cas system can be divided into six types (Types Ⅰ-Ⅵ),which differ in terms of their nucleic acid target,number and arrangement of cas genes,and the composition of a silencing complex. | Yangao Huo Tao Li Nan Wang Qinghua Dong Xiangxi Wang Tao Jiang | 2018 | Cell Research2018，28，12： | 0 |
| 14 | Study on Chaos Created by Hopf Bifurcation of One Kind of Financial System and Its Application显示文摘From a mathematical model of one kind complicated financial system, corresponding local topological structures of such kind system on condition of certain parametercombination, unstable equilibrium point of the system, conditions on which Hopf bifurcation is created and stability of the limit circle corresponding to the Hopf bifurcation as well as condition on which the limit circle is stable have been studied. From relationship between each parameter and the Hopf bifurcation all the way to route which leads to chaos etc have been studied. Following the above, conditions on which complicated behaviors created locally in such kind system has been analyzed. By applying fractal dimension, Lyapunov index, the intrinsic complexity of the system on such condition has been studied, and result of the numerical simulation proves the theory of this paper correct. | JunhaiMa BiaoRen YanGao | 2004 | Journal of Systems Science and Information2004，2，3： | 0 |
| 15 | Synthesis and Characterization of Ion-exchange Copolyimide显示文摘 | LiRongZHANG ChunQingZHANG YanGAO ZhiYuanJIA | 2004 | Chinese Chemical Letters2004，15，1： | 0 |
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