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| 1 | Effect of minor Sc addition on microstructure and stress corrosion cracking behavior of medium strength Al–Zn–Mg alloy显示文摘Influence of Sc content on microstructure and stress corrosion cracking behavior of medium strength Al–Zn–Mg alloy have been investigated by optical microscopy, scanning electron microscopy, electron backscatter diffraction, transmission electron microscopy and slow strain rate test. The results indicate that the addition of Sc results in the formation of the quaternary coherent Al_3(Sc, Zr, Ti) dispersoids during homogenization treatment, which will inhibit the dynamic recrystallization behavior. The number density of Al_3(Sc, Zr, Ti) particles increases with the increase of Sc content, and thus the recrystallization fraction of hot-extruded alloy is reduced and the peak strength in two-stage artificial aging sample is enhanced. At the same time, the wide of precipitation free zone is reduced, and the content of Zn and Mg in grain boundary particles and precipitation free zone is increased with the increase of Sc content. In peak-aged state, the 0.06 wt% Sc added alloy shows the better stress corrosion cracking resistance than the Sc-free alloy because of the reduction of recrystallization fraction and the interrupted distribution of grain boundary precipitates along grain boundary. However, the further addition of Sc to 0.11 wt% will result in the deterioration of stress corrosion cracking resistance due to the increase of electrochemical activity of grain boundary particles and precipitation free zone as well as hydrogen embrittlement. | Zhaoming Li Haichang Jiang Yunli Wang Duo Zhang Desheng Yan Lijian Rong | 2018 | Journal of Materials Science & Technology2018，34，7： | 14 |
| 2 | Climate change in Mt. Qomolangma region since 1971显示文摘Using monthly average, maximum, minimum air temperature and monthly precipitation data from 5 weather stations in Mt. Qomolangma region in China from 1971 to 2004, climatic linear trend, moving average, low-pass filter and accumulated variance analysis methods, the spatial and temporal patterns of the climatic change in this region were analyzed. The main findings can be summarized as follows: (1) There is obvious ascending tendency for the interannual change of air temperature in Mt. Qomolangma region and the ascending tendency of Tingri, the highest station, is the most significant. The rate of increasing air temperature is 0.234 oC/decade in Mt. Qomolangma region, 0.302 oC/decade in Tingri. The air temperature increases more strongly in non-growing season. (2) Compared with China and the global average, the warming of Mt. Qomolangma region occurred early. The linear rates of temperature increase in Mt. Qomolangma region exceed those for China and the global average in the same period. This is attributed to the sensitivity of mountainous regions to climate change. (3) The southern and northern parts of Mt. Qomolangma region are quite different in precipitation changes. Stations in the northern part show increasing trends but are not statistically significant. Nyalam in the southern part shows a decreasing trend and the sudden decreasing of precipitation occurred in the early 1990s. (4) Compared with the previous studies, we find that the warming of Mt. Qomolangma high-elevation region is most significant in China in the same period. The highest automatic meteorological comprehensive observation station in the world set up at the base camp of Mt. Qomolangma with a height of 5032 m a.s.l will play an important role in monitoring the global climate change. | YANG Xuchao ZHANG Yili ZHANG Wei YAN Yuping WANG Zhaofeng DING Mingjun CHU Duo | 2006 | Journal of Geographical Sciences2006，16，3： | 12 |
| 3 | Firebird sirolimus eluting stent versus bare mental stent in patients with ST-segment elevation myocardial infarction显示文摘在那里的背景是关于在有圣片断举起的病人的药 eluting stent 的价值的很少证据心肌的梗塞(STEMI ) 。我们有希望地设计了使随机化的控制审判比较鲜艳的小鸟 sirolimus eluting stent (鲜艳的小鸟 stent ) 和赤裸的金属 stent (BMS ).Methods 的安全和功效有在一个年时期期间注册的 STEMI 的病人被使随机化经历鲜艳的小鸟 stent 或 BMS 的培植,并且临床并且 angiographic 后续。现在的学习的主要端点晚是在里面损害在 6 个月的腔损失( LLL ),和第二等的端点在一个年时期期间在 6 months.Results 包括 stent 血栓和主要不利心脏的事件(向), 156 个病人被使随机化进鲜艳的小鸟 stent 组(有 57.8 年的平均年龄的 101 个病人)或 BMS 组(有 59.7 年的 55 个病人平均)。六月的 angiographic 后续在分别地分到鲜艳的小鸟 stent 和 BMS 的 66.3% 病人和 63.7% 是可得到的。当 3.6% , 30.9% 和 36.4% 在 BMS 组织时,在鲜艳的小鸟 stent 组在 6 月的后续,死亡,目标容器 revascularization (TVR ) 和向是 2.0% , 6.9% 和 9.9%(P0.05 ) 。稍尖的血栓分别地在两个组发生在 1 个病人。吝啬的 LLL 在鲜艳的小鸟 sirolimus eluting stent 的 BMS group.Conclusion 培植是在鲜艳的小鸟 stent 组对 0.72 公里的 0.18 公里因为 STEMI 可以极大地与 BMS 相比与尖锐 / 稍尖的 stent 血栓的低发生在 6 个月减少 TVR 和向。 | GAO Hai YAN Hong-bing ZHU Xiao-ling LI Nan AI Hui WANG Jian LI Shi-ying YANG Duo | 2007 | Chinese Medical Journal2007，，10： | 9 |
| 4 | miR164c and miR168a regulate seed vigor in rice^∞显示文摘Micro RNAs(miRNAs)are key regulators of gene expression in many important biological processes of plants.However,few miRNAs have been shown to regulate seed vigor.Here,we conducted microarray assays to analyze miRNA expression levels in seeds of the rice(Oryza sativa L.)cultivar ZR02.Results showed significant differences in the expression of 11 miRNAs between artificially aged and untreated control seeds.Among these,osa-miR164c was transcriptionally upregulated,while osamiR168 a was downregulated in artificially aged seeds;this was verified by quantitative real-time PCR analysis.Under the same aging condition,osa-miR164c overexpression in OE164c transgenic seeds and osa-miR168a silencing in MIM168a transgenic seeds of the rice cultivar Kasalath led to lower germination rates,whereas osa-miR164c silencing Rin MIM164c and osa-miR168a overexpression in OE168a resulted in higher seed germination rates compared with wild-type seeds.Meanwhile,changes in cytomembrane permeability of seeds and in the expression level of osa-miR164c target genes(OsPM27 and OsPSK5)and osamiR168a target genes(OsAGO1 and OsPTR2)under aging conditions coincided with changes in seed vigor induced by osa-miR164c and osa-miR168 a.Thus,genetic manipulation of miRNAs has important implications in the development of crop cultivars with high vigor and extended life span of seeds. | Yan Zhou Shiqi Zhou Liping Wang Duo Wu Hailan Cheng Xu Du Dandan Mao Chunlai Zhang Xiaocheng Jiang | 2020 | Journal of Integrative Plant Biology2020，62，4： | 7 |
| 5 | Building a sequence map of the pig pan-genome from multiple de novo assemblies and Hi-C data显示文摘Pigs were domesticated independently in the Near East and China,indicating that a single reference genome from one individual is unable to represent the full spectrum of divergent sequences in pigs worldwide.Therefore,12 de novo pig assemblies from Eurasia were compared in this study to identify the missing sequences from the reference genome.As a result,72.5 Mb of nonredundant sequences(~3% of the genome)were found to be absent from the reference genome(Sscrofa11.1)and were defined as pan-sequences.Of the pan-sequences,9.0 Mb were dominant in Chinese pigs,in contrast with their low frequency in European pigs.One sequence dominant in Chinese pigs contained the complete genic region of the tazarotene-induced gene 3(TIG3)gene which is involved in fatty acid metabolism.Using flanking sequences and Hi-C based methods,27.7% of the sequences could be anchored to the reference genome.The supplementation of these sequences could contribute to the accurate interpretation of the 3D chromatin structure.A web-based pan-genome database was further provided to serve as a primary resource for exploration of genetic diversity and promote pig breeding and biomedical research. | Xiaomeng Tian Ran Li Weiwei Fu Yan Li Xihong Wang Ming Li Duo Du Qianzi Tang Yudong Cai Yiming Long Yue Zhao Mingzhou Li Yu Jiang | 2020 | Science China(Life Sciences)2020，63，5： | 7 |
| 6 | Influence of diet intake on liver function test显示文摘InfluenceofdietintakeonliverfunctiontestCHENGShuQuan,ZHANGJiFang,ZHANGZiFu,QIANMeiYan,GUOXiaoLing,SHANGWenZhangandLIDuo... | CHENG Shu Quan, ZHANG Ji Fang, ZHANG Zi Fu, QIAN Mei Yan, GUO Xiao Ling, SHANG Wen Zhang and LI Duo Jing Department of Medical Laboratory, The Central Hospital of Jiaozuo Coal Mine Administration, Jiaozuo 454150, Henan Province, China | 1997 | World Journal of Gastroenterology1997，3，4： | 3 |
| 7 | Optimization of Hydrolysis Conditions for the Isolation of Angiotensin-I Converting Enzyme(ACE) Inhibitory Peptides from Rhopilema hispidum显示文摘To obtain the maximum angiotensin-I converting enzyme(ACE) inhibitory activity, the protein hydrolysis conditions of the jellyfish Rhopilema hispidum were optimized using response surface methodology(RSM). Trypsin was selected to produce R. hispidum protein hydrolysates(RPH) with ACE inhibitory activity. The optimal parameters for producing protein hydrolysates with the highest ACE inhibitory activity were as follows: hydrolysis time 5 h, hydrolysis temperature 50℃, and the enzyme-to-substrate ratio 6%. Under these conditions, the ACE inhibitory rate of RPH could reach 64.28% ± 5.72%. In addition, RPH contained high levels of Gly, Glu, Pro, Ala, Asp and Arg, with a molecular weight distribution range of 0.32–6.84 kDa. The following three novel ACE inhibitory peptides were isolated and identified: Ile-Gly-Glu-Thr-Gly-Pro, Gly-Ala-Thr-Gly-Pro-Ala-Gly-Tyr-Val and Gly-AlaPhe-Gly-Pro-Gly-Gly-Leu-Val-Gly-Arg-Pro. The IC_(50) values of the ACE inhibitory activity of these three purified peptides were 19.07, 27.42 and 31.26 μmol L^(-1), respectively. These results suggested that proteins and peptides isolated from R. hispidum could be utilized as antihypertensive functional food sources. | SUN Zhenliang QIN Huanlong CAO Duo YAN Xuebing LI Hao HUANG Linsheng QU Xiao KONG Cheng WANG Man | 2018 | Journal of Ocean University of China2018，17，6： | 2 |
| 8 | Dietary ellagic acid supplementation attenuates intestinal damage and oxidative stress by regulating gut microbiota in weanling piglets显示文摘Intestinal oxidative stress triggers gut microbiota dysbiosis,which is involved in the etiology of postweaning diarrhea and enteric infections.Ellagic acid(EA)can potentially serve as an antioxidant supplement to facilitate weaning transition by improving intestinal oxidative stress and gut microbiota dysbiosis.Therefore,we aimed to investigate the effects of dietary EA supplementation on the attenuation of intestinal damage,oxidative stress,and dysbiosis of gut microbiota in weanling piglets.A total of126 piglets were randomly assigned into 3 groups and treated with a basal diet and 2 m L saline orally(Ctrl group),or the basal diet supplemented with 0.1%EA and 2 m L saline orally(EA group),or the basal diet and 2 m L fecal microbiota suspension from the EA group orally(FEA group),respectively,for 14 d.Compared with the Ctrl group,EA group improved growth performance by increasing average daily feed intake and average daily weight gain(P<0.05)and decreasing fecal scores(P<0.05).EA group also alleviated intestinal damage by increasing the tight junction protein occludin(P<0.05),villus height,and villus height-to-crypt depth ratio(P<0.05),while decreasing intestinal epithelial apoptosis(P<0.05).Additionally,EA group enhanced the jejunum antioxidant capacity by increasing the total antioxidant capacity(P<0.01),catalase(P<0.05),and glutathione/oxidized glutathione(P<0.05),but decreased the oxidative metabolite malondialdehyde(P<0.05)compared to the Ctrl group.Compared with the Ctrl group,EA and FEA groups increased alpha diversity(P<0.05),enriched beneficial bacteria(Ruminococcaceae and Clostridium ramosum),and increased metabolites short-chain fatty acids(P<0.05).Correspondingly,FEA group gained effects comparable to those of EA group on growth performance,intestinal damage,and intestinal antioxidant capacity.In addition,the relative abundance of bacteria shifted in EA and FEA groups was significantly related to the examined indices(P<0.05).Overall,dietary EA supplementation could improve growth performance and attenuate intestinal damage and oxidative stress by regulating the gut microbiota in weanling piglets. | Wenxia Qin Baoyang Xu Yuwen Chen Wenbo Yang Yunzheng Xu Juncheng Huang Ting Duo Yihua Mao Guozong Zhou Xianghua Yan Libao Ma | 2022 | Animal Nutrition2022，，4： | 2 |
| 9 | Research progress in rare earths and their composites based electrode materials for supercapacitors显示文摘Supercapacitor is an imminent potential energy storage system,and acts as a booster to the batteries and fuel cells to provide necessary power density.In the last decade,carbon and carbonaceous materials,conducting polymers and transition metal oxide/hydroxide based electrode materials have been made to show a remarkable electrochemical performance.Rare-earth materials have attracted significant research attention as an electrode material for supercapacitor applications based on their physicochemical properties.In this review,rare earth metals,rare earth metal oxides/hydroxides,rare-earth metal chalcogenides,rare-earth metal/carbon composites and rare-earth metal/metal oxide composites based electrode materials are discussed for supercapacitors.We also discuss the energy chemistry of rare-earth metal-based materials.Besides the factors that affect the performance of the electrode materials,their evaluation methods and supercapacitor performances are discussed in details.Finally,the future outlook in rare-earth-based electrode materials is revealed towards its current developments for supercapacitor applications. | Subasri Arunachalam Balakrishnan Kirubasankar Duo Pan Hu Liu Chao Yan Zhanhu Guo Subramania Angaiah | 2020 | Green Energy & Environment2020，5，3： | 2 |
| 10 | Meroterpenthiazole A, a unique meroterpenoid from the deep-sea-derived Penicillium allii-sativi, significantly inhibited retinoid X receptor (RXR)-α transcriptional effect显示文摘A novel meroterpenoid,named meroterpenthiazole A(1),was isolated from the deep-sea-derived Penicillium allii-sativi.Its structure was established by extensive spectroscopic and computational methods.Meroterpenthiazole A bears a rare benzothiazole moiety in nature.Compound 1 significantly inhibited retinoid X receptor(RXR)-α transcriptional effect(K_(D)=12.3 μmol/L) through a novel binding mechanism. | Chun-Lan Xie Duo Zhang Kai-Qiang Guo Qing-Xiang Yan Zheng-Biao Zou Zhi-Hui He Zhen Wu Xiao-Kun Zhang Hai-Feng Chen Xian-Wen Yang | 2022 | Chinese Chemical Letters2022，33，4： | 2 |
| 11 | Presence of antibodies against low-density lipoprotein receptor-related protein 4 and impairment of neuromuscular junction in a Chinese cohort of amyotrophic lateral sclerosis显示文摘Amyotrophic lateral sclerosis (ALS) is a heterogeneous disorder characterized by a loss of upper and lower motor neurons with neither clear pathogenesis nor effective treatment. Thus, potential biomarkers are needed to classify the disease and find new drug targets. Previous studies have shown that auto-antibodies against the low-density lipoprotein receptor-related protein 4 (LRP4), called the anti-LRP4 antibodies, are found in ~23% patients of Greek and Italian ALS cohorts,[1] and in 10% of the American ALS population.[2] Anti-LRP4 antibodies were previously identified in myasthenia gravis (MG), the most common neuromuscular junction (NMJ) disorder, and were shown to cause NMJ abnormality in animal studies.[3] Here, we studied anti-LRP4 antibodies in Chinese patients and investigated the correlation between anti-LRP4 antibodies and abnormal neuromuscular transmission in ALS. | Lin Lei Xin-Ming Shen Shu-Yan Wang Yan Lu Suo-Bin Wang Hai Chen Zheng Liu Ya-Sheng Ouyang Jian-Ying Duo Yu-Wei Da Zhi-Guo Chen | 2019 | Chinese Medical Journal2019，，12： | 1 |
| 12 | Mercury in alpine fish from four rivers in the Tibetan Plateau显示文摘As a global pollutant, high levels of mercury(Hg) have been found in remote ecosystem due to the long range atmospheric transport. In this study, a total of 60 fish samples were collected from four rivers across the Tibetan Plateau to study the accumulation of Hg in remote and high-altitude aquatic environment. The total Hg(THg) and methylmercury(MeHg) in fish muscles ranged from 11 to 2097 ng/g dry weight(dw)(average: 819 ng/g dw)and from 14 to 1960 ng/g dw(average: 756 ng/g dw), respectively. Significantly positive linear relationships were observed between the THg(r = 0.591, p < 0.01, n = 36) and MeHg concentrations(r = 0.473, p < 0.01, n = 36) with the trophic level of fish from Lhasa River,suggesting trophic transfer and biomagnification of Hg in this aquatic ecosystem. Moreover,the THg levels in fish had significantly positive correlations with the length(r = 0.316,p < 0.05, n = 60) and weight(r = 0.271, p < 0.05, n = 60) of fish. The high levels of Hg were attributed to the slow growth and long lifespan of the fish under this sterile and cold environment. Risk assessment revealed that the consumption of Oxygymnocypris stewartii,Schizothorax macropogon, Schizothorax waltoni, Schizopygopsis younghusbandi and Schizothorax o'connori would lead to a high exposure to Me Hg. | Junjuan Shao Jianbo Shi Bu Duo Chengbin Liu Yan Gao Jianjie Fu Ruiqiang Yang Guibin Jiang | 2016 | Journal of Environmental Sciences2016，28，1： | 1 |
| 13 | An engineering method of determining the delamination fracture toughness of composite laminates显示文摘 | Yan X Q Du S Y Duo W | 1991 | Engineering Fracture Me- chanics1991，39，4： | 1 |
| 14 | The diagnostic value of serum hybrid capture 2 (CH2) HPV DNA in cervical cancer: a systematic review and meta-analysis显示文摘 | Duo Yin Yan Jiang Ning Wang Ling Ouyang Yanming Lu Yao Zhang Heng Wei Shulan Zhang | 2014 | Tumor Biology2014，，9： | 1 |
| 15 | Long-range atmospheric transport and alpine condensation of short-chain chlorinated paraffins on the southeastern Tibetan Plateau显示文摘Pristine alpine regions are ideal regions for investigating the long-range atmospheric transport and cold trapping effects of short chain chlorinated paraffins(SCCPs).The concentrations and alpine condensation of SCCPs were investigated in lichen samples collected from the southeastern Tibetan Plateau.The concentrations of SCCPs ranged from 3098 to 6999 ng/g lipid weight(lw)and appeared to have an increasing trend with altitude.For congeners,C10 dominated among all the congener groups.The different environmental behavior for different congener groups was closely related to their octanol-air partition coefficient(Koa).C10 congeners showed an increasing trend with altitude,whereas C13 congeners were negatively correlated with altitude.Volumetric bioconcentration factors(BCF)of SCCPs reached 8.71 in lichens,which were higher than other semivolatile organic compounds(SVOCs)such as organochlorine pesticides(OCPs),polybrominated diphenyl ethers(PBDEs),polychlorinated biphenyls(PCBs),and hexabromocyclododecane(HBCD).These results suggested that SCCPs were prone to accumulate in the lichen from the air and provided evidence for the role of lichens as a suitable atmospheric indicator in the Tibetan Plateau. | Huijuan Li Duo Bu Yan Gao Nali Zhu Jing Wu Xiangfeng Chen Jianjie Fu Yawei Wang Aiqian Zhang Guibin Jiang | 2021 | Journal of Environmental Sciences2021，33，1： | 1 |
| 16 | Influence of Freeze-Thaw Cycles on Bonded Interface Performance between CFRP and High Strength Concrete显示文摘 | Lei Hong Run Min Duo Su Yan Wang Lu Xi Li | 2014 | Applied Mechanics and Materials . 2014 (638)2014，，638： | 1 |
| 17 | Microstructure and wear properties of TiCN/Ti coatings on titanium alloy by laser cladding显示文摘 | YANG Yu-ling ZHANG Duo YAN Wei ZHENG Yi-ran | 2010 | Optics and Lasers in Engineering2010，48，1： | 1 |
| 18 | Acid inhibition effect of ilaprazole on Helicobacter pylori‐negative healthy volunteers: An open randomized cross‐over study显示文摘 | Yi QiDU Wen YuanGUO Duo WuZOU Xian BaoZHAN ZhenLI Jin HongHU Yan FangGONG JiaHE Jian PingLU Zhao ShenLI | 2012 | Journal of Digestive Diseases2012，，2： | 1 |
| 19 | Flame stability monitoring and characterization through digital imaging and spectral analysis显示文摘 | Duo Sun Gang Lu Hao Zhou Yong Yan | 2011 | Measurement Science and Technology2011，，11： | 1 |
| 20 | An intelligent estimation method for product design time 显示文摘 | XU Duo YAN Hongsen | 2006 | International Journal of Advanced Manufacturing Technology2006，30，78： | 1 |
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