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| 1 | Glacial distribution and mass balance in the Yarlung Zangbo River and its influence on lakes显示文摘Glaciers in the Yarlung Zangbo River witness severe glacial retreat nowadays,which gives important influence on lake processes in the region.We have studied glacial distribution,glacial mass balance and found large deficit in glacial mass and its impact in the region.Our study also integrated the variation in glacial-fed lakes of the Nam Co and Ranwu Lake,and presented an initial assessment of the impact of glacial mass balance on lakes.The study has shown a significant contribution of glacial melting to recent lake expansion and lake level rising. | YAO TanDong LI ZhiGuo YANG Wei GUO XueJun ZHU LiPing KANG ShiChang WU YanHong YU WuSheng | 2010 | Chinese Science Bulletin2010，55，20： | 34 |
| 2 | Statistics-based Optimization of the Polarimetric Radar Hydrometeor Classification Algorithm and Its Application for a Squall Line in South China显示文摘A modified hydrometeor classification algorithm(HCA) is developed in this study for Chinese polarimetric radars. This algorithm is based on the U.S. operational HCA. Meanwhile, the methodology of statistics-based optimization is proposed including calibration checking, datasets selection, membership functions modification, computation thresholds modification,and effect verification. Zhuhai radar, the first operational polarimetric radar in South China, applies these procedures. The systematic bias of calibration is corrected, the reliability of radar measurements deteriorates when the signal-to-noise ratio is low, and correlation coefficient within the melting layer is usually lower than that of the U.S. WSR-88D radar. Through modification based on statistical analysis of polarimetric variables, the localized HCA especially for Zhuhai is obtained,and it performs well over a one-month test through comparison with sounding and surface observations. The algorithm is then utilized for analysis of a squall line process on 11 May 2014 and is found to provide reasonable details with respect to horizontal and vertical structures, and the HCA results—especially in the mixed rain–hail region—can reflect the life cycle of the squall line. In addition, the kinematic and microphysical processes of cloud evolution and the differences between radardetected hail and surface observations are also analyzed. The results of this study provide evidence for the improvement of this HCA developed specifically for China. | Chong WU Liping LIU Ming WEI Baozhu XI Minghui YU | 2018 | Advances in Atmospheric Sciences2018，35，3： | 32 |
| 3 | Chemical and optical properties of aerosols and their interrelationship in winter in the megacity Shanghai of China显示文摘A field campaign on air quality was carried out in Shanghai in winter of 2012. The concentrations of NO, NO2, NOx, SO2, CO, and PM2.5increased during haze formation. The average masses of SO42-, NO3-and NH4+were 10.3, 11.7 and 6.7 μg/m3 during the haze episodes, which exceeded the average(9.2, 7.9, and 3.4 μg/m3) of these components in the non-haze days. The mean values for the aerosol scattering coefficient(b sp), aerosol absorption coefficient(b ap) and single scattering albedo(SSA) were 288.7, 27.7 and0.91 Mm-1, respectively. A bi-peak distribution was observed for the mass concentrations of CO, NO, NO2, and NOx. More sulfate was produced during daytime than that in the evening due to photochemical reactions. The mass concentration of NH4+achieved a small peak at noontime. NO3-showed lower concentrations in the afternoon and higher concentrations in the early morning. There were obvious bi-peak diurnal patterns for b sp and b ap as well as SSA. b sp and b ap showed a positive correlation with PM2.5mass concentration.(NH4)2SO4, NH4NO3, organic mass, elemental carbon and coarse mass accounted for 21.7%, 19.3%, 31.0%, 9.3% and 12.3% of the total extinction coefficient during non-haze days, and 25.6%, 24.3%, 30.1%, 8.1% and 8.2% during hazy days. Organic matter was the largest contributor to light extinction. The contribution proportions of ammonium sulfate and ammonium nitrate to light extinction were significantly higher during the hazy time than during the non-haze days. | Tingting Han Liping Qiao Min Zhou Yu Qu Jianfei Du Xingang Liu Shengrong Lou Changhong Chen Hongli Wang Fang Zhang Qing Yu Qiong Wu | 2015 | Journal of Environmental Sciences2015，27，1： | 14 |
| 4 | Review of single-camera stereo-digital image correlation techniques for full-field 3D shape and deformation measurement显示文摘Single-camera stereo-digital image correlation(stereo-DIC) techniques have gained increasing attentions and demonstrated excellent prospects in the experimental mechanics community owing to their prominent advantages of cost-effectiveness,compactness, and the avoidance of the complicated camera synchronization. Using additional optical devices, e.g. a diffraction grating, a bi-prism or a set of planar mirrors, pseudo stereo images of a test sample surface can be recorded with a single camera.By correlating these stereo images using DIC, full-field three-dimensional(3 D) shape and deformation can be retrieved. This review comprehensively summarizes the historical development, methodologies, strengths and weaknesses of the diffraction grating-based, prism-based, four-mirror-adaptor-based single-camera stereo-DIC techniques, and the recently proposed novel full-frame single color camera-based stereo-DIC technique for full-field 3 D shape and deformation measurement. The optical arrangements, principles and calibration procedures of these single-camera stereo-DIC techniques are described in detail. Since high-speed deformation measurement is efficiently achieved by combining the single-camera stereo-DIC with one high-speed camera, single-camera stereo-DIC techniques show great potential in impact engineering, vibration and other dynamic tests. | PAN Bing YU LiPing ZHANG QianBing | 2018 | Science China(Technological Sciences)2018，61，1： | 14 |
| 5 | Modelling operation parameters of UAV on spray effects at different growth stages of corns显示文摘Currently,unmanned aerial vehicles(UAVs)were widely applied to spray for pest and disease control.However,spray effect can be further improved by setting operation parameters more reasonably and scientifically.Therefore,this study attempts to derive the relationship between operation parameters and spray effect.Different growth stages were distinguished by various corn heights.A six-rotor UAV was operated at different heights and velocities to test pesticides spray effects for corns at different growth stages.Different plant canopy coverage rate and penetrating coefficients were obtained,according to which,the effects on droplet deposition rate caused by different UAVs’operation parameters were analyzed.Droplet penetrating coefficients were applied as indexes to evaluate and select UAVs operation parameters for corns at different growth stages respectively.Mathematical models of droplet penetrating coefficients with UAVs operation parameters were established for corns at all growth stages.The determination coefficients(R2)of all models were greater than 0.90 and average relative errors were within 20%,which asserted high forecasting accuracy of droplet penetrating rate.With the help of the models,parameters like operating height away from the bottom of corns and UAVs velocities were further analyzed,which guided the optimization of parameter settings and selection of spray methods for corns at different growth stages. | Zheng Yongjun Yang Shenghui Zhao Chunjiang Chen Liping Yubin Lan Tan Yu | 2017 | International Journal of Agricultural and Biological Engineering2017，10，3： | 13 |
| 6 | Comparison between TVDI and CWSI for drought monitoring in the Guanzhong Plain,China显示文摘Temperature vegetation dryness index(TVDI) and crop water stress index(CWSI) are two commonly used remote sensing-based agricultural drought indicators. This study explored the applicability of monthly moderate resolution imaging spectroradiometer(MODIS) normalized difference vegetation index(NDVI) and land surface temperature(LST) data for agricultural drought monitoring in the Guanzhong Plain,China in 2003. The data were processed using TVDI,calculated by parameterizing the relationship between the MODIS NDVI and LST data. We compared the effectiveness of TVDI against CWSI,derived from the MOD16 products,for drought monitoring. In addition,the surface soil moisture and monthly precipitation were collected and used for verification of the results. Results from the study showed that:(1) drought conditions measured by TVDI and CWSI had a number of similarities,which indicated that both CWSI and TVDI can be used for drought monitoring,although they had some discrepancies in the spatiotemporal characteristics of drought intensity of this region; and(2) both standardized precipitation index(SPI) and SM contents at the depth of 10 and 20 cm had better correlations to CWSI than to TVDI,indicating that there were more statistically significant relationships between CWSI and SPI/SM,and that CWSI is a more reliable indicator for assessing and monitoring droughts in this region. | BAI Jian-jun YU Yuan Liping Di | 2017 | Journal of Integrative Agriculture2017，16，2： | 10 |
| 7 | 1型糖尿病患者的血糖控制,心脏自身免疫和心血管病的长期风险显示文摘血糖控制不佳与1型糖尿病(type 1diabetes mellitus,T1DM)患者的心血管病风险增加有关;然而,对T1DM的特异性机制知之甚少。在T1DM中,心肌损伤可诱发持续的心脏自身免疫。慢性高血糖症引起心肌损伤,高血糖诱导的心脏自身免疫可能导致长期心血管病并发症的可能性。 | Sousa GR Pober D Galderisi A Lv H Yu L Pereira AC Doria A Kosiborod M Lipes MA 刘莉 叶鹏 | 2019 | 中华高血压杂志2019，27，1： | 8 |
| 8 | Regression model to estimate flood impact on corn yield using MODIS NDVI and USDA cropland data layer显示文摘Flood events and their impact on crops are extremely significant scientific research issues; however,flood monitoring is an exceedingly complicated process. Flood damages on crops are directly related to yield change,which requires accurate assessment to quantify the damages. Various remote sensing products and indices have been used in the past for this purpose. This paper utilizes the moderate resolution imaging spectroradiometer(MODIS) weekly normalized difference vegetation index(NDVI) product to detect and further quantify flood damages on corn within the major corn producing states in the Midwest region of the US. County-level analyses were performed by taking weighted average of all pure corn pixels(>90%) masked by the United States Department of Agriculture(USDA) Cropland Data Layer(CDL). The NDVI-based time-series difference between flood years and normal year(median of years 2000–2014) was used to detect flood occurrences. To further measure the impact of the flood on corn yield,regression analysis between change in NDVI and change in corn yield as independent and dependent variables respectively was performed for 30 different flooding events within growing seasons of the corn. With the R2 value of 0.85,the model indicates statistically significant linear relation between the NDVI and corn yield. Testing the predictability of the model with 10 new cases,the average relative error of the model was only 4.47%. Furthermore,small error(4.8%) of leave-one-out cross validation(LOOCV) along with smaller statistical error indicators(root mean square error(RMSE),mean absolute error(MAE),and mean bias error(MBE)),further validated the accuracy of the model. Utilizing the linear regression approach,change in NDVI during the growing season of corn appeared to be a good indicator to quantify the yield loss due to flood. Additionally,with the 250 m MODIS-based NDVI,these yield losses can be estimated up to field level. | Ran jay Shrestha Liping Di Eugene G. Yu Lingjun Kang SHAO Yuan-zhen BAI Yu-qi | 2017 | Journal of Integrative Agriculture2017，16，2： | 8 |
| 9 | Thorny roses:The motivations and economic consequences of holding equity stakes in financial institutions for China's listed nonfinancial firms显示文摘The reforms of China's financial system have significantly changed the country's financial sector. One noteworthy phenomenon is that many nonfinancial firms have obtained equity stakes in financial institutions. This study investigates the motivations behind and economic consequences of this recent proliferation of investments in financial institutions by nonfinancial listed firms. We find that the motivations for holding equity stakes in financial institutions include alleviating the pressure of industry competition, reducing transaction costs, and diversification to reduce risk. These investments, however, have double-edged effects on the performance of the investing firms. While their investment income increases, their operating income and overall return on assets decrease, as the investment income cannot compensate for the decrease in other operating income. The investing firms' cost of debt also increases, their cash-holding decreases, and stock price performance does not improve after investing in financial institutions. These effects contrast with the enthusiasm nonfinancial listed firms have for investing in financial institutions. The empirical findings in this study can inform financial industry regulators and decision-makers in listed firms. We advise nonfinancial firms to be cautious when considering investing in financial institutions. | Liping Xu Yu Xin | 2017 | China Journal of Accounting Research2017，，2： | 7 |
| 10 | Synthesis of Large-Area, Few-Layer Graphene on Iron Foil by Chemical Vapor Deposition显示文摘我们表明一个简单、可控制的方法综合大区域,由优化化学蒸汽免职(CVD ) 的铁底层上的很少层 graphene 用甲烷和氢的混合物的方法。基于 Fe-C 阶段图的分析,为 Fe 表面上的 graphene 的成功的合成的一个合适的过程被设计。适当温度和冷却过程被发现在高度水晶的很少层 graphene 的合成很重要。基于 Graphene 的地效果晶体管(联邦货物税) 设备用产生很少层 graphene 被制作,并且与 3001150 cm2/ 的提取活动性显示出好质量(V 敢椠 ?? 敤瑢吗? | Yunzhou Xue Bin Wu Yunlong Guo Liping Huang Lang Jiang Jianyi Chen Dechao Geng Yunqi Liu Wenping Hu Gui Yu | 2011 | Nano Research2011，4，12： | 7 |
| 11 | Recruitment of endogenous progenitor cells by erythropoietin loaded particles for in situ cartilage regeneration显示文摘Cartilage injury affects millions of people throughout the world,and at this time there is no cure.While transplantation of stem cells has shown some success in the treatment of injured cartilage,such treatment is limited by limited cell sources and safety concerns.To overcome these drawbacks,a microscaffolds system was developed capable of targeting,reducing the inflammatory response and recruiting endogenous progenitor cells to cartilage-defect.Erythropoietin(EPO)-loaded-hyaluronic acid(HA)microscaffolds(HA+EPO)were fabricated and characterized.HA-microscaffolds showed good cell-compatibility and could target chondrocytes via CD44 receptors.HA+EPO was designed to slowly release EPO while recruiting progenitor cells.Finally,the ability of HA+EPO to repair cartilage-defects was assessed using a rabbit model of full-thickness cartilagedefect.Our results showed that the intra-articular administration of EPO,HA,and EPO+HA reduced the number of inflammatory cells inside the synovial-fluid,while EPO+HA had the greatest anti-inflammatory effects.Furthermore,among all groups,EPO+HA achieved the greatest progenitor cell recruitment and subsequent chondrogenesis.The results of this work support that,by targeting and localizing the release of growthfactors,HA+EPO can reduce inflammatory responses and promote progenitor cells responses.This new platform represents an alternative treatment to stem-cell transplantation for the treatment of cartilage injury. | Amirhossein Hakamivala Shuxin li Kayti Robinson YiHui Huang Shuai Yu Baohong Yuan Joseph Borrelli Jr. Liping Tang | 2020 | Bioactive Materials2020，5，1： | 7 |
| 12 | Spatial and temporal variation in magnetic properties of street dust in Lanzhou City,China显示文摘Urban environmental problems are of increasing concern. Lanzhou is a large industrial city in North-west China. Street dust samples representing different temporal and spatial scales were collected for magnetic properties study. Magnetic measurements indicate a high concentration of magnetic minerals in Lanzhou street dust, dominated by pseudo-single domain (PSD) magnetite. The concentration of magnetic materials is distinctly high in winter and spring, low in autumn. Similarly, higher concentra-tions associated with heavy industry, concentrated residential development, and vehicular traffic sug-gest mixed contributions of magnetic material from both anthropogenic and natural sources. χ_lf and SOFT% are effective magnetic parameters that denote seasonal differences among magnetic proper-ties in street dust, convenient and economical methods for monitoring street dust pollution. | WANG Guan XIA DunSheng LIU XiuMing CHEN FaHu YU Ye YANG LiPing CHEN JianHui ZHOU AiFeng | 2008 | Chinese Science Bulletin2008，53，12： | 7 |
| 13 | Multi-functional bismuth-doped bioglasses: combining bioactivity and photothermal response for bone tumor treatment and tissue repair显示文摘Treatment of large bone defects derived from bone tumor surgery is typically performed in multiple separate operations,such as hyperthermia to extinguish residual malignant cells or implanting bioactive materials to initiate apatite remineralization for tissue repair;it is very challenging to combine these functions into a material.Herein,we report the first photothermal(PT)effect in bismuth(Bi)-doped glasses.On the basis of this discovery,we have developed a new type of Bi-doped bioactive glass that integrates both functions,thus reducing the number of treatment cycles.We demonstrate that Bi-doped bioglasses(BGs)provide high PT efficiency,potentially facilitating photoinduced hyperthermia and bioactivity to allow bone tissue remineralization.The PT effect of Bi-doped BGs can be effectively controlled by managing radiative and non-radiative processes of the active Bi species by quenching photoluminescence(PL)or depolymerizing glass networks.In vitro studies demonstrate that such glasses are biocompatible to tumor and normal cells and that they can promote osteogenic cell proliferation,differentiation,and mineralization.Upon illumination with near-infrared(NIR)light,the bioglass(BG)can efficiently kill bone tumor cells,as demonstrated via in vitro and in vivo experiments.This indicates excellent potential for the integration of multiple functions within the new materials,which will aid in the development and application of novel biomaterials. | Liping Wang Nicholas J.Long Lihua Li Yao Lu Mei Li Jiangkun Cao Yu Zhang Qinyuan Zhang Shanhui Xu Zhongmin Yang Chuanbin Mao Mingying Peng | 2018 | Light(Science & Applications)2018，7，1： | 6 |
| 14 | Magnesium effects on behavior and substance P mRNA expression in the midbrain of a rat migraine model显示文摘BACKGROUND:Substance P participates in pain transmission and modulation,suggesting a close association with migraine headaches.The clinical application of magnesium has been effective in treating migraines,and the action mechanisms underlying migraines correlate with substance P expression. OBJECTIVE:To analyze different magnesium doses on behavior and substance P mRNA expression in the midbrain of a rat migraine model,and to determine the action pathway of migraine treatment using magnesium. DESIGN,TIME AND SETTING:A completely randomized,controlled,animal experiment was performed at the Experimental Animal Center and Central Laboratory in the Second Hospital of Jilin University between 2007 and 2008. MATERIALS:Magnesium sulfate(25%) was supplied by Tianjin Pharmaceutical Jiaozuo,China. Nitroglycerin was provided by Shanxi Kangbao Biological,China.Substance P primer sequence was synthesized by TaKaRa Biotechnology(Dalian),China. METHODS:A total of 36 healthy,adult,Wistar rats were randomly assigned to 6 groups:control, migraine,low- and high-dose magnesium sulfate treated,and low- and high-dose magnesium sulfate control,with 6 rats in each group.Migraines were induced by subcutaneous injection of 10 mg/kg nitroglycerin in the migraine and low- and high-dose magnesium sulfate treated groups, and 2 mL/kg physiological saline was administered to rats in the control and low- and high-dose of magnesium sulfate control groups.Five minutes following administration,rats in low-dose groups were intraperitoneally injected with 100 mg/kg magnesium sulfate,while those in high-dose groups were injected with 300 mg/kg magnesium sulfate.No interventions were administered to the control and migraine groups. MAIN OUTCOME MEASURES:At 2 hours after nitroglycerin injection,substance P mRNA expression in the rat midbrain was measured by real-time quantitative polymerase chain reaction.At 60-90 minutes after nitroglycerin injection,behavioral changes of pain were analyzed in the experimental rats. RESULTS:The migraine group exhibited significantly lower levels of substance P mRNA expression compared with the control group(P<0.05).Following magnesium sulfate injection,substance P mRNA expression increased,compared with the migraine and control groups(P<0.05).In the low-and high-dose magnesium sulfate treated groups,pain behavior was remarkably ameliorated, compared with the migraine group(P<0.05),particularly with the high-dose injection(P<0.05). CONCLUSION:Magnesium relieved pain behaviors in a rat migraine model in a dose-dependent manner,and the therapeutic effect was achieved in conjunction with increased substance P expression in the midbrain. | Tingmin Yu Gang Yao Liping Zhang | 2009 | Neural Regeneration Research2009，4，11： | 6 |
| 15 | Rare earth element geochemistry of hydrothermal deposits from Southwest Indian Ridge显示文摘The REE compositions of hydrothermal deposits and basalt samples from the Southwest Indian Ridge (SWIR) were determined with ICP-MS.The results show that there are significant differences between different types of samples although all samples show relative LREE enrichment.The contents of REE in hydrothermal sulfides and alterated rocks samples are lower (from 7.036 × 10 6 to 23.660 × 10 6),while those in the white chimney deposits are relatively higher (ranging from 84.496 × 10 6 to 103.511 × 10 6).Both of them are lower than basalts.Chondrite-normalized REE distribution patterns show that sulfides and alterated rocks samples are characterized by significant positive Eu anomalies.On the contrary,white chimney deposits have obvious negative Eu anomalies,which may be caused by abundant calcite existing in the white chimney samples.Both the content and distribution pattern of REE in sulfides suggest that REE most possibly is originally derived from hydrothermal fluids,but influenced by the submarine reducing ore-forming environment,seawater convection,mineral compositions as well as the constraint of mineral crystallizations. | CAO Zhimin CAO Hong TAO Chunhui LI Jun YU Zenghui SHU Liping | 2012 | Acta Oceanologica Sinica2012，31，2： | 6 |
| 16 | CEACAM6 promotes tumor migration, invasion, and metastasis in gastric cancer显示文摘(CEACAM6 ) Carcinoembryonic 抗原相关的房间粘附分子 6 证明在许多 humancancers 的增加的表示,和它的在表示上与提高的移植被联系,侵略,并且在 vivo 转移。这里,我们报导 CEACAM6 在房间衬里的胃的癌症(GC ) 和肿瘤纸巾是起来调整的。在 MKN-45 和 SGC-7901 GC 房间的 Over-expressionof CEACAM6 在 athymic 老鼠在 vitro 和转移支持了移植和侵略,而 MKN-28 和 SNU-16 GC 房间的移植和侵略被 knockdownof CEACAM6 压制。当 CEACAM6 是 over-expressedin SGC-7901 房间时,我们也观察到类固醇受体激活剂(C-SRC ) phosphorylation 被增加。一起拿,这些结果建议 CEACAM6 在 GC 作为 oncoprotein 工作并且可以是 importantmetastatic biomarker 和治疗学的目标。 | Yunqiang Zhang Mingde Zang Jianfang Li Jun Ji Jianian Zhang Xiaolei Liu Ying Qu Liping Su Chen Li Yinyan Yu Zhenggang Zhu Bingya Liu Min yan | 2014 | Acta Biochimica et Biophysica Sinica2014，46，4： | 5 |
| 17 | A nonsynonymous SNP in human cytosolic sialidase in a small Asian population results in reduced enzyme activity: potential link with severe adverse reactions to oseltamivir显示文摘oseltamivir 的使用,广泛地是的 stockpiled 为在可能的鸟的流行性感冒的使用的药之一流行,被报导了与 neuropsychiatricdisorders 和严重皮肤反应被联系,首先在日本。这里,我们在 dbSNP 数据库识别了非同义的 SNP (单个核苷酸多型性) , R41Q 在 humancytosolic sialidase 的酶的活跃地点附近,是 oseltamivir 的目标的病毒 neuraminidase 的一个相当或相同事物。在欧洲、非洲的美国人口的 9.29% 亚洲人口和没有的这 SNPoccurred。Ourstructural 分析和 Ki 大小使用试管内 sialidase 试金显示这 SNPcould 增加人的 sialidase 的非计划中的有约束力的亲密关系到 oseltamivir 羧化物, oseltamivir 的活跃形式,因此减少 sialidase 活动。另外,这 SNP 自己与一项内在地更低的 sialidase 活动导致酶,由它的增加的 Km 证明 Vmax 珍视并且减少。理论上,到有这 SNP 的人的 oseltamivir 的管理可能进一步减少他们的 sialidase 活动。我们注意 oseltamivir 的 reportedneuropsychiatric 副酌和人的 sialidase-relateddisorders 的已知的症状的类似。我们建议这个充实亚洲人的 sialidase 变化由 SNP 引起了,在同型结合的形式可能,可以与对 oseltamivir 的某些严重不利反应被联系。 | Chuan-Yun Li Quan Yu Zhi-Qiang Ye Ying Sun Quanyuan He Xiao-Mo Li Wuxue Zhang Jingchu Luo Xiaocheng Gu Xiaofeng Zheng Liping Wei | 2007 | Cell Research2007，17，4： | 5 |
| 18 | The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus. | Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang | 2016 | Science China(Life Sciences)2016，59，9： | 5 |
| 19 | Exploration of presence/absence variation and corresponding polymorphic markers in soybean genome显示文摘This study was designed to reveal the genome‐wide distribution of presence/absence variation(PAV) and to establish a database of polymorphic PAV markers in soybean. The 33 soybean whole‐genome sequences were compared to each other with that of Williams 82 as a reference genome. A total of 33,127 PAVs were detected and 28,912 PAV markers with their primer sequences were designed as the database NJAUSoyPAV_1.0. The PAVs scattered on whole genome while only 518(1.8%) overlapped with simple sequence repeats(SSRs) in BARCSOYSSR_1.0database. In a random sample of 800 PAVs, 713(89.13%) showed polymorphism among the 12 differential genotypes. Using 126 PAVs and 108 SSRs to test a Chinese soybean germplasm collection composed of 828 Glycine soja Sieb. et Zucc. and Glycine max(L.) Merr. accessions, the per locus allele number and its variation appeared less in PAVs than in SSRs. The distinctness among alleles/bands of PCR(polymerase chain reaction) products showed better in PAVs than in SSRs, potential in accurate marker‐assisted allele selection. The association mapping results showed SSR t PAV was more powerful than any single marker systems.The NJAUSoyPAV_1.0 database has enriched the source of PCR markers, and may fit the materials with a range of per locus allele numbers, if jointly used with SSR markers. | Yufeng Wang Jiangjie Lu Shouyi Chen Liping Shu Reid G.Palmer Guangnan Xing Yan Li Shouping Yang Deyue Yu Tuanjie Zhao Junyi Gai | 2014 | Journal of Integrative Plant Biology2014，56，10： | 5 |
| 20 | Effect of pickling processes on the microstructure and properties of electroless Ni–P coating on Mg–7.5Li–2Zn–1Y alloy显示文摘The electroless plating Ni–P is prepared on the surface of Mg–7.5Li–2Zn–1Y alloys with different pickling processes.The microstructure and properties of Ni–P coating are investigated.The results show that the Ni–P coatings deposited using the different pickling processes have a different high phosphorus content amorphous Ni–P solid solution structure,and the Ni–P coatings exhibit higher hardness.There is higher phosphorus content of Ni–P amorphous coating using 125 g/L Cr O3and 110 ml/L HNO3(w68%)than using 180 g/L Cr O3and 1 g/L KF during pre-treatment,and the coating structure is more compact,and the Ni–P coatings exhibit more excellent adhesion with substrate(Fcup to22 N).The corrosion potential of Ni–P coating is improved and exhibits good corrosion resistance.As a result,Mg-7.5Li-2Zn-1Y alloy is remarkably protected by the Ni–P coating. | Chunjie Xu Liping Chen Ling Yu Jinxiao Zhang Zhongming Zhang Jincheng Wang | 2014 | Progress in Natural Science:Materials International2014，24，6： | 5 |
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