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	题名	作者	年代	出处	被引量
1	Differential Inhibition of Nav1.7 and Neuropathic Pain by Hybridoma-Produced and Recombinant Monoclonal Antibodies that Target Nav1.7显示文摘The voltage-gated Na^+ channel subtype Nav1.7 is important for pain and itch in rodents and humans. We previously showed that a Nav1.7-targeting monoclonal antibody(SVmab) reduces Na+ currents and pain and itch responses in mice. Here, we investigated whether recombinant SVmab(rSVmab) binds to and blocks Nav1.7 similar to SVmab. ELISA tests revealed that SVmab was capable of binding to Nav1.7-expressing HEK293 cells,mouse DRG neurons, human nerve tissue, and the voltagesensor domain Ⅱ of Nav1.7. In contrast, rSVmab showed no or weak binding to Nav1.7 in these tests. Patch-clamp recordings showed that SVmab, but not rSVmab, markedly inhibited Na+ currents in Nav1.7-expressing HEK293 cells. Notably, electrical field stimulation increased the blocking activity of SVmab and rSVmab in Nav1.7-expressing HEK293 cells. SVmab was more effective than rSVmab in inhibiting paclitaxel-induced mechanical allodynia. SVmab also bound to human DRG neurons and inhibited their Na^+ currents. Finally, potential reasons for the differential efficacy of SVmab and rSVmab and future directions are discussed.	Sangsu Bang Jiho Yoo Xingrui Gong Di Liu Qingjian Han Xin Luo Wonseok Chang Gang Chen Sang-Taek Im Yong Ho Kim Judith A.Strong Ma-Zhong Zhang Jun-Ming Zhang Seok-Yong Lee Ru-Rong Ji	2018	Neuroscience Bulletin2018，34，1：	2
2	Influence of overweight and obesity on upper endoscopic findings 显示文摘	Kim HJ Yoo TW Park DI	2007	Journal of Gastroenterology and Hepatolgy2007，22，4：	1
3	Use of chitosan to improve dyeability of DP-finished cotton (II) 显示文摘	SHINY YOO DI	1998	Journal of Applied Polymer Science1998，67，9：	1
4	The influence of a poly- morphism at position -857 of e tumour necrosis factor gene on clinical response to etanercept therapy in rheumatoid arthritis显示文摘	Kang CP Lee KW Yoo DI	2005	Rheumatology2005，44，：	1
5	Bailout stent deployment during coil embolization of intracranial aneurysms显示文摘	Yoo E Kim DJ Kim DI	2009	AJNR Am J Neuroradiol2009，30，5：	1
6	Antimicrobial finishing of polypropylene nonwoven fabric by treatment with chitosan oligomer显示文摘	Shin Y Yoo DI Min K	1999	J Appl Polym Sci1999，，74：	1
7	Antimicrobial finishing of polypropylene nonwoven fabric by treatment with chitnsan olignmer显示文摘	Shin Y Yoo DI Min K	1999	J Applied Polymer Science1999，74，：	1
8	Inhibition of GSK-3 reduces infarct volume and improves neurobehavioral functions显示文摘	Koh SH Yoo AR Chang DI	2008	Biochem Biophys Res Commun2008，371，4：	1
9	FTIR analysis of cellulose treated with sodium hydroxide and carbon dioxide显示文摘	Oh SY Yoo DI Shin Y	2005	Carbohydrate Research2005，340，3：	1
10	In vivo cell tracking of canine allo- genic mesenchymal stem cells administration via renal arterial cathe- terlzation and physiopathologieal effects on the kidney in two healthy dogs显示文摘	Yoo JH Park C Jung DI	2011	J Vet Med Sci2011，73，2：	1
11	Bailout stent deployment during coil embolization of intracranial aneurysms显示文摘	Yoo E Kim DJ Kim DI	2009	AJNR2009，30，：	1
12	FTIR analysis of cellulose treated with sodium hydroxide and carbon dioxide 显示文摘	OH SY YOO DI SHIN Y	2005	Carbohydr Research2005，340，3：	1
13	Gene amplification and protein overexpression of HER -2/neu in human extrahepatic eholangiocareinoma as detected by chromogenic in situ hybridization and immunohistochemistry: its prognostic implication in node - positive patients 显示文摘	Kim FIJ Yoo TW Park DI	2007	Ann Oncol2007，18，5：	1
14	Is gastric cancer a new indication for surveillance colonoscopy? Colon cancer is increased in gastric cancer patients显示文摘	Oh SY Park DI Yoo TW	2006	Korean J Gastroenterol2006，47，3：	1
15	Influence of overweight and obesity on upper endoscopic findings 显示文摘	Kim HJ Yoo TW Park DI	2007	J Gastroenterol Hepatol2007，22，4：	1
16	Bailout stent deployment during coil embolization of intracranial aneurysms显示文摘	Yoo E Kim DJ Kim DI		0，，：	1
17	In vivo cell tracking of canine allo-genic mesenchymal stem cells administration via renal arterial cath-eterization and physiopathological effects on the kidney in twohealthy dogs显示文摘	Yoo JH Park C Jung DI	2011	J Vet Med Sci2011，73，2：	1
18	Antimicrobial finishing of polypropylene nonwoven fabric by treatment with chitosan oligomer显示文摘	Shin Y Yoo DI Min K	1999	J Appl Polym Sci1999，74，：	1
19	Influence of overweight and obesity on upper endoscopic findings显示文摘	Kim H J Yoo TW Park DI	2007	Journal of Gastroenterology and Hepatolgy2007，22，4：	1
20	Bailout stent deployment during coil embolization of intracranial aneurysms显示文摘	Yoo E Kim DJ Kim DI	2009	AJNR2009，30，：	1

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