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150篇 您的检索式:作者名="YL Tan"
    题名 作者 年代 出处 被引量
1Rabeprazole vs esomeprazole in non-erosive gastro-esophageal reflux disease: A randomized, double-blind study in urban Asia显示文摘AIM:Gastro-esophageal reflux disease (GERD) is becoming increasingly common in Asia. Data on the efficacy of proton pump inhibitors in patients with non-erosive GERD (NERD)in Asia is lacking. This double-blind study compared the efficacy and safety of rabeprazole with esomeprazole in relief of symptoms in patients with NERD.METHODS: One hundred and thirty-four patients with reflux symptoms of NERD and normal endoscopy were randomized to receive rabeprazole 10 mg or esomeprazole 20 mg once daily for 4 wk. Symptoms were recorded in a diary and changes in severity of symptoms noted.RESULTS: At 4 wk of treatment, rabeprazole 10 mg and esomeprazole 20 mg were comparable with regards to the primary endpoint of time to achieve 24-h symptomfree interval for heartburn 8.5 d vs9 d and regurgitation 6 d vs 7.5 d. Rabeprazole and esomeprazole were also similarly efficacious in term of patient's global evaluation with 96% of patients on rabeprazole and 87.9% of patients on esomeprazole, reporting that symptoms improved(P=NS). Satisfactory relief of day- and night-time symptoms was achieved in 98% of patients receiving rabeprazole and 81.4% of patients receiving esomeprazole. Adverse events were comparable in both groups (P = NS).CONCLUSION: Rabeprazole 10 mg has a similar efficacy and safety profile in Asians with NERD as esomeprazole 20 mg. Further study is necessary to investigate whether the small differences between the two drugs seen in this study are related to the improved pharmacodynamicpro perties of rabeprazole. Both drugs were well tolerated.KM Fock EK Teo TL Ang TS Chua TM Ng YL Tan 2005World Journal of Gastroenterology2005,11,20:8
2Polymorphisms in DNA base excision repair genes ADPRT and XRCC1 and risk of lung cancer显示文摘Zhang XM Miao XP Liang G Hao BT Wang YG Tan W Li Y Guo YL He FC Wei QY Lin DX 2006中国生物学文摘2006,20,4:2
3Down-regulation of glucocorticoid receptor and its relationship to the induction of rat liver tyrosine aminotransferase显示文摘Yang YL Tan JX Xu RB 1989Steroid Biochem1989,,32:1
4Cutaneous silent periods in the evaluation of cord compression in cervical spondylosis显示文摘Lo YL Tan YE Dan YF 2007J Neurol2007,254,:1
5Disrupted antioxidant enzyme activity and elevated lipid peroxidation products in schizophrenic patients with tardive dyskinesia显示文摘Zhang XY Tan YL Zhou DF 2007Clin Psychiatry2007,68,5:1
6High-sensitivity C-re- active protein predicts contrast-induced nephropathy af- ter primary percutaneous coronary intervention 显示文摘Liu Y Tan N Zhou YL 2012J Nephrol2012,25,:1
7High-sensitivity C-reactive protein pre- dicts contrast-induced nephropathy after primary percutaneous coro- nary intervention显示文摘Liu Y Tan N Zhou YL 2012J Nephrol2012,25,3:1
8Giant mixed-type perinephric liposarcoma显示文摘Tan GY Chong YL Ramesh K 2004Int Urol Nephrol2004,36,3:1
9Altered BDNF is correlated to cognition impairment in schizophrenia patients with tardive dyskinesia显示文摘Wu JQ Chenda C Tan YL 2015Psychopharmacology2015,232,1:1
10The contrast medium volume to estimated glomerular filtration rate ratio as a predictor of contrast-induced nephropathy after primary percutaneous coronary intervention 显示文摘Liu Y Tan N Zhou YL 2012Int Urol Nephrol2012,44,1:1
11Decreased BDNF in serum of patients with chronic schizophrenia on long-term treatment with antipsychotics显示文摘Tan YL Zhou DF Cao LY 2005Neurosci Lett2005,37,12:1
12Decreased plasma levels of brain-derived neurotrophic factor(BDNF)during mixed episodes of bipolar disorder显示文摘Wu JQ Chenda C Tan YL 2015J Affect Disord2015,171,:1
13The interplay between BDNF and oxidative stress in chronic schizophrenia显示文摘Zhang XY Chen DC Tan YL 2015PsychoNeuroendocrinology2015,51,2:1
14Antioxidant enzymes and lipid peroxidation in different forms of schizophrenia treated with typical and atypical antip- sychotics显示文摘Zhang XY Tan YL Cao LY 2006Schizophr Res2006,81,23:1
15Idl, inhibitor of differentiation, is a key protein mediating anti-tumor responses of gamma-tocotrienol in breast cancer cells显示文摘Yap WN Zaiden N Tan YL 2010Cancer Lett2010,291,2:1
16The amino acid composition solubility and emulsifying properties of sweet potato protein显示文摘Mu TH Tan SS Xue YL 0,,:1
17Targeting the minimum water flowrate using water cascade analysis technique 显示文摘Manan ZA Tan YL Foo DCY 2004AIChE J2004,50,12:1
18High-sensi- tivity C-reactive protein predicts contrast- induced nephropathy after primary perc utaneous coronary intervention显示文摘Liu Y Tan N Zhou YL 2012J Neph- rol2012,25,10:1
19Repetitive hypoglossal nerve stimulation in myasthenia gravis显示文摘Lo YL Leoh TH Tan YE 2002Clin Neurophysiol2002,113,8:1
20High-sensitivity C-reactive protein prediets contrast-induced nephropathy after primary percutaneous coronary in- tervention 显示文摘Liu Y Tan N Zhou YL 2011J Nephro12011,10,7:1
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