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| 1 | ANALYSIS OF WATER QUALITY IN SHALLOW LAKES WITH A TWO-DIMENSIONAL FLOW-SEDIMENT MODEL显示文摘The governing equation for sediment pollutions was derived based on the turbulent diffusion of pollutants in shallow lakes. Coupled with shallow water equations, a depth-averaged 2-D flow and water quality model was developed. By means of the conservation law, a proposed differential equation for the change of sediment pollutants was linked to the 2-D equations. Under the framework of the finite volume method, the Osher approximate Riemann solver was employed to solve the equations. An analytical resolution was used to examine the model capabilities. Simulated results matched the exact solutions especially well. As an example, the simulation of CODMn in the Wuli Lake, a part of the Taihu lake, was conducted, which led to reasonable results. This study provides a new approach and a practical tool for the simulation of flow and water quality in shallow lakes. | JI Yong ZhANG Jie YAO ei ZHAO Di-hua | 2007 | Journal of Hydrodynamics2007，19，4： | 12 |
| 2 | JGES guidelines for colorectal endoscopic submucosal dissection/endoscopic mucosal resection显示文摘 | Shinji Tanaka Hiroshi Kashida Yutaka Saito Naohisa Yahagi Hiroo Yamano Shoichi Saito Takashi Hisabe Takashi Yao Masahiko Watanabe Masahiro Yoshida Shin‐ei Kudo Osamu Tsuruta Ken‐ichi Sugihara Toshiaki Watanabe Yusuke Saitoh Masahiro Igarashi Takashi Toyon | 2015 | Digestive Endoscopy2015，，4： | 2 |
| 3 | The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues显示文摘 | Thangarajah H Yao D Chang EI | 2009 | Proc Natl Acad Sci U S A2009，106，13： | 1 |
| 4 | Equilibria,kinetics,and mechanism in the bicarbonate activation ofhydrogen peroxide :oxidation of sulfides by peroxymonocarbonate显示文摘 | Richardson D E Yao H R Frank K M ei al | 2000 | Journal of the American Chemical Society2000，122，8： | 1 |
| 5 | Defects in expression of genes related to synaptic vesicle trafficking in frontal cortex of Alzheimer' s disease 显示文摘 | Yao PJ Zhu M Pyun EI | 2003 | Neurobiol Dis2003，12，2： | 1 |
| 6 | Experimentalstudy on physiological responses and thermal comfort under various ambient temperatures 显示文摘 | Yao Ye Lian Zhiw ei Liu Weiw ei | 2008 | Physiology & Behavior2008，93，12： | 1 |
| 7 | Effect of heat-press conditionson electrospun membranes for desalination by direct contact mem-brane tlistillation显示文摘 | Yao M Yun C W Tijing L D ei al | 2016 | Desalination2016，378，： | 1 |
| 8 | The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues 显示文摘 | Thangarajah H Yao Daehun Chang EI | 2009 | Proc Natl Acad Sci U S A2009，106，13： | 1 |
| 9 | The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues 显示文摘 | Thangara]ah H Yao D Chang EI | 2009 | Proc Natl Acad Sci USA2009，106，13： | 1 |
| 10 | The molecular basis forimpaired hypoxia - induced VEGF expression in diabetic tissues显示文摘 | Thangarajah H Yao D Chang EI | 2009 | Proc Natl Acad Sci USA2009，106，13： | 1 |
| 11 | The molecular basis for impaired hypoxia-induced VEGF expression in diabetic tissues显示文摘 | Thangarajah H Yao D Chang EI | 2009 | Proc Natl Acad Sci USA2009，106，13： | 1 |
| 12 | The molecular basis for impaired hypoxia induced VEGF expression in diabetic tissues显示文摘 | Thangarajah H Yao D Chang EI | 2009 | Proe Natl Acad Sei USA2009，106，13： | 1 |
| 13 | A game-theoretic methodof fair resource allocation for cloud computing services显示文摘 | W'ei Gui-yi Vasilakos A Zheng Yao | 2010 | The Jour-nal of Supercomputing2010，54，2： | 1 |
| 14 | Isoproterenol activates extracel-lular signal - regulated protein kinases in cardiomyocytes through cal-cineurin 显示文摘 | ZOU YZ YAO A 2HU W D ei al | 2001 | Circulation2001，104，1： | 1 |
| 15 | Resolving the variability ofCDOM fluorescence to differentiate the sources and fate of DOMin Lake Taihu and its tributaries 显示文摘 | Yao X Zhang Y L Zhu G W ei al | 2011 | Chemosphere2011，82，2： | 1 |
| 16 | Defects in expression of genes relatedto synaptic vesicle trafficking in frontal cortex of Alzheimei’sdisease显示文摘 | Yao PJ Zhu MyPyun EI | 2003 | Neurobiol Dis2003，12，2： | 1 |
| 17 | Machine learning and bioinformatics to identify biomarkers in response to Burkholderia pseudomallei infection in mice显示文摘Objective:In the realm of Class I pathogens,Burkholderia pseudomallei(BP)stands out for its propensity to induce severe pathogenicity.Investigating the intricate interactions between BP and host cells is imperative for comprehending the dynamics of BP infection and discerning biomarkers indicative of the host cell response process.Methods:mRNA extraction from BP-infected mouse macrophages constituted the initial step of our study.Employing gene expression arrays,the extracted RNA underwent conversion into digital signals.The percentile shift method facilitated data processing,with the identification of genes manifesting significant differences accomplished through the application of the t-test.Subsequently,a comprehensive analysis involving Gene Ontology enrichment and Kyoto Encyclopedia of Genes and Genomes pathway was conducted on the differentially expressed genes(DEGs).Leveraging the ESTIMATE algorithm,gene signatures were utilized to compute risk scores for gene expression data.Support vector machine analysis and gene enrichment scores were instrumental in establishing correlations between biomarkers and macrophages,followed by an evaluation of the predictive power of the identified biomarkers.Results:The functional and pathway associations of the DEGs predominantly centered around G protein-coupled receptors.A noteworthy positive correlation emerged between the blue module,consisting of 416 genes,and the StromaScore.FZD4,identified through support vector machine analysis among intersecting genes,indicated a robust interaction with macrophages,suggesting its potential as a robust biomarker.FZD4 exhibited commendable predictive efficacy,with BP infection inducing its expression in both macrophages and mouse lung tissue.Western blotting in macrophages confirmed a significant upregulation of FZD4 expression from 0.5 to 24 h post-infection.In mouse lung tissue,FZD4 manifested higher expression in the cytoplasm of pulmonary epithelial cells in BP-infected lungs than in the control group.Conclusion:Thesefindings underscore the upregulation of FZD4 expression by BP in both macrophages and lung tissue,pointing to its prospective role as a biomarker in the pathogenesis of BP infection. | YAO FANG FEI XIA FEIFEI TIAN L EI QU FANG YANG JUAN FANG ZHENHONG HU HAICHAO LIU | 2024 | BIOCELL2024，48，4： | 0 |
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