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| 1 | ISAR成像快速最小熵相位补偿方法显示文摘针对逆合成孔径雷达(ISAR)成像,该文提出一种快速运动补偿算法,该算法基于二维图像熵,并通过相位补偿的快速迭代,使图像熵逐渐达到最小,从而实现雷达像的自聚焦.实测数据处理结果表明,同现有方法相比,该方法不仅保证熵意义上的最佳聚焦效果,而且还具有较高收敛速度。 | 邱晓晖 Heng Wang Cheng Alice Yeo Siew Yam | 2004 | 电子与信息学报2004，26，10： | 11 |
| 2 | 施工现场安全危险源实时监控与安全风险预测方法研究显示文摘对国内外建筑业施工现场安全风险的研究进行了文献综述,针对目前研究的不足之处,提出了施工现场安全危险源实时监控和安全风险实时预测的示意性模型,并详细解释了该模型的含义和方法。研究将提供一种基于前馈信号的施工现场安全危险源实时监控和安全风险实时预测的方法;并通过将现有研究的视角引入到施工现场关键安全危险源的前馈信号上,为进一步的研究打下良好的理论基础。 | 吴伟巍 Patrick T.I. LAM 李启明 Michael C.H. YAM David A.S. CHEW | 2010 | 中国工程科学2010，12，3： | 9 |
| 3 | 胞浆小滴可能是精子运动和正常精子形成的标志显示文摘哺乳动物生精过程后期精细胞胞浆脱落后,有一个微小部分经常会残留于精子鞭毛上,被称为胞浆小滴。胞浆小滴被认为在精子体积的调整中起到重要作用。然而,我们观察到含有胞浆小滴的精子大多显示出运动活力,而不含有胞浆小滴的精子则鲜有运动活力,说明在附睾成熟过程中胞浆小滴的存在对精子运动起重要作用。在本研究中,我们分析了小鼠及猴的精子在附睾成熟期间含有及不含有胞浆小滴的精子运动能力获得的关系,以及胞浆小滴在精子尾部位置的改变的关系。我们也检测了3种晚期精子生成缺陷基因敲除小鼠的精子胞浆小滴。我们的数据显示胞浆小滴是暂时存在于附睾精子上的正常附属器官,正常的胞浆小滴形态及位置与精子附睾成熟过程中正常的运动能力形成相关。胞浆小滴的异常形成,胞浆小滴的缺失或者异常的胞浆小滴预示着精子形成缺陷。如果胞浆小滴是精子运动形成的基础,那么胞浆小滴可以成为非激素类男性避孕药的理想的药物靶点。 | Hui Xu Shui-Qiao Yuan Zhi-Hong Zheng Wei Yam | 2013 | Asian Journal of Andrology2013，15，6： | 5 |
| 4 | 色素上皮细胞衍生因子:一种高效的新生血管抑制因子显示文摘色素上皮细胞衍生因子 (pigm ent epithelium- derived factor,PEDF)是最先在视网膜色素上皮细胞培养液中发现的细胞因子 ,属于丝氨酸蛋白酶抑制剂基因家族 ,但不具备抗蛋白酶活性。 PEDF有营养神经效果 ,保护神经元免受快速神经毒性侵害 (如谷氨酸毒性 )作用及“胶质细胞静息”特性。PEDF还能抑制血管内皮细胞移行 ,促进血管内皮细胞凋亡 ,正常角膜、玻璃体中PEDF含量较高 ,在低氧环境中降低。PEDF具有抗新生血管诱导因子的作用 ,目前 PEDF被视为最有效的细胞内新生血管抑制因子之一。可能对治疗神经元损伤和抑制血管生成特别有效。 | 金姬 关明 Hin-Fai Yam | 2002 | 眼科新进展2002，22，1： | 5 |
| 5 | Corneal re-innervation following refractive surgery treatments显示文摘Laser refractive surgery is one of the most performed surgical procedures in the world. Although regarded safe and efficient, it has side effects. All of the laser based refractive surgical procedures invoke corneal nerve injury to some degree. The impact of this denervation can range from mild discomfort to neurotrophic corneas. Currently, three techniques are widely used for laser vision correction: small incision lenticule extraction, laser-assisted keratomileusis in situ and photorefractive keratotomy. Each of these techniques affects corneal innervation differently and has a different pattern of nerve regeneration. The purpose of this review is to summarize the different underlying mechanisms for corneal nerve injury and compare the different patterns of corneal reinnervation. | Francisco Bandeira Nur Zahira Yusoff Gary Hin-Fai Yam Jodhbir Singh Mehta | 2019 | Neural Regeneration Research2019，14，4： | 4 |
| 6 | Reductive demetalation of manganese corroles:The substituent effect显示文摘锰 corroles 的减少的 demetalation 在 CH2Cl2/HCl 被调查(水) 由把 SnCl2 用作减少代理人的溶剂。demetalation 收益显著地取决于 corrole macrocycle 的取代者,这被发现。充满电子的锰 corrole 比电子缺乏的更容易经历减少的 demetalation。锰 5,10,15-tris (苯基) 的孤立的减少的 demetalation 收益在现在的系统的 corrole 是中等的(46%) 。至于电子缺乏的 Mn (III ) 5,10,15-tris (pentafluorophenyl ) corrole,在 HOAc 鈥揌2 SO4 (V/V = 3:1 ) 的导致酸的 demetalation 与 67% 的孤立的收益更好。 | Hai Yang Liu Ling Chen Fei Yam Hai Ying Zhan Xiao Ying Xiang Li Wang Huan Feng Jiang Chi Kwong Chang | 2008 | Chinese Chemical Letters2008，19，8： | 3 |
| 7 | Non-invasive versus invasive mechanical ventilation for respiratory failure in severe acute respiratory syndrome显示文摘Background Severe acute respiratory syndrome is frequently complicated by respiratory failure requiringventilatory support.We aimed to compare the efficacy of non-invasive ventilation against invasive mechanicalventilation treating respiratory failure in this disease.Methods Retrospective analysis was conducted on all respiratory failure patients identified from the HongKong Hospital Authority Severe Acute Respiratory Syndrome Database.Intubation rate, mortality and secondaryoutcome of a hospital utilizing non-invasive ventilation under standard infection control conditions ( NIVHospital) were compared against13 hospitals using solely invasive ventilation (IMVHospitals).Multiple logisticregression analyses with adjustments for confounding variables were performed to test for association betweenoutcomes and hospital groups.Results Both hospital groups had comparable demographics and clinical profiles, but NIV Hospital (42patients) had higher lactate dehydrogenase ratio and worse radiographic score on admission and ribavirin-corticosteroid commencement.Compared to IMV Hospitals (451 patients), NIV Hospital had lower adjustedodds ratios for intubation (0.36, 95% CI 0.164 -0.791,P=0.011) and death (0.235, 95% CI 0.077 -0.716,P=0.011), and improved earlier after pulsed steroid rescue.There were no instances of transmission ofsevere acute respiratory syndrome among health care workers due to the use of non-invasive ventilation.Conclusion Compared to invasive mechanical ventilation, non-invasive ventilation as initial ventilatory supportfor acute respiratory failure in the presence of severe acute respiratory syndrome appeared to be associated withreduced intubation need and mortality. | Loretta YC Yam Alfred YF Chan Thomas MT Cheung Eva LH Tsui Jane CK Chan Vivian CW Wong | 2005 | Chinese Medical Journal2005，，17： | 3 |
| 8 | Appended corrole manganese complexes:Catalysis and axial-ligand effect显示文摘A series of N-base appended corroles and their manganese complexes were synthesized and their binding constants with three different nitrogenous ligands,triethylamine,N-methylimidazole and pyridine,were evaluated by spectroscopy.Kinetic studies indicated that the presence of appended Ndonor ligands may cause a significant enhancement of the rate of oxygen atom transfers(OAT) from(oxo)manganese(V) corrole to alkene,and the stronger axial ligand binding has impact on the rate of the oxidation reaction.Turnover frequency(TOF) for the catalytic oxidation of alkenes by appended manganese corroles varies with the following ligand order:acetamido < pyridyl < imidazolyl.The influence of the external axial ligands on the catalytic epoxidation was investigated by using appended acetamido manganese corrole as catalyst,with the results revealing that N-methylimidazole gave the best enhancement on the yields of total oxidation products among the investigated nitrogenous ligands. | Nga-Chun Ng Mian HR Mahmood Chi-K.Chang Hai-Yang Liu Fei Yam Lam-Lung Yeung | 2014 | Chinese Chemical Letters2014，25，4： | 3 |
| 9 | Decomposition and Reformulation of Banxia Baizhu Tianma Decoction:A Vasodilatory Approach显示文摘Objective To decompose and reformulate Banxia Baizhu Tianma Decoction(BBT) in order to optimize its ratio for vasodilatory effect.The fingerprints of these six component herbs were also studied via Tri-step FTIR analysis.Methods The herbal components of BBT were extracted separately with different solvents,such as 95%ethanol,50%ethanol,and distilled water.The vasodilatory effect of the extracts was studied using the in vitro pre-contracted aortic ring model.Among these extracts,the water extracts of Pinellia ternata[PT(W)]and Citri reticulatae[CR(W)],50%ethanol extracts of Castrodia elata[GE(50)]and Clycyrrhiza uralensis[GU(50)],and 95%ethanol extracts of Atractylodes macrocephala[AM(E)],and Poria cocos[PC(E)]were selected for the orthogonal stimulus-response compatibility group study due to their high effectiveness in vasodilation.Results The best combination ratio(G2) was GE(50),GU(50),AM(E),PC(E),CR(W),and PT(W) at EC_0,EC_5,EC_5,EC_5,EC_5,and EC_5,with EC_(50) of(0.06 ± 0.01) mg/mL.Comparison between the vasodilatory effects of extracts derived from G2 and BBT were also studied.From the results,the 50%ethanol extract following G2 ratio was found to be most potent extract with the highest vasodilatory effect compared with other extracts derived from G2 or BBT,with EC_(50) of(0.05 ±0.005) mg/mL.Conclusion The optimum ratio and appropriate extraction method for the new BBT formulae are obtained.G2 is determined as the best formulae with the highest potency in producing the vasodilatory effect on isolated rat aortic rings.The results obtained suggest that 50%ethanol is found to be the best solvent to extract the vasoactive compounds of G2 in order to exhibit the highest efficacy of vasodilatory effect. | Chu Shan Tan Yean Chun Loh Yung Sing Ch'ng Mariam Ahmad Mohd.Zaini Asmawi Mun Fei Yam | 2017 | Chinese Herbal Medicines2017，9，2： | 3 |
| 10 | Hydroclimatological changes in the Bagmati River Basin, Nepal显示文摘在多山的河盆的 hydroclimatological 变化上的学习在最近的年里吸引了大兴趣。在温度,降水和河分泌物模式的变化能被看作河盆的 hydroclimatological 变化的指示物。在这研究,温度(最大值和最小) ,猛冲,和分泌物,从 1980 ~ 2009 的数据被用来在 Bagmati 河盆检测 hydroclimatological 变化,尼泊尔。简单线性回归和 Mann-Kendall 测试统计数值被用来检验温度,降水,和分泌物的重要趋势。温度的增加的趋势在所有季节被发现,尽管变化率在为最小、最大的温度的不同季节是不同的。然而,更强壮的温暖趋势在整个盆与最小相比在最大的温度被发现。降水和分泌物趋势在季风前季节正在增加,但是在季风以后的季节减少。降水的重要趋势不能在冬季被观察,尽管分泌物趋势正在减少。而且,山峰分泌物的紧张正在增加,尽管在最大的降水事件的紧张没有一个明显的变化。所有这些变化在尼泊尔的多山的河盆在农业,水力发出的电力植物,和自然生物多样性上有效果,这被期望。 | Yam Prasad DHITAL 汤秋鸿 施建成 | 2013 | Journal of Geographical Sciences2013，23，4： | 2 |
| 11 | Role of Small Extracellular Vesicles in Liver Diseases:Pathogenesis,Diagnosis,and Treatment显示文摘Extracellular vesicles(EVs)are vesicular bodies that bud off from the cell membrane or are secreted virtually by all cell types.Small EVs(sEVs or exosomes)are key mediators of cell-cell communication by delivering their cargo,including proteins,lipids,or RNAs,to the recipient cells where they induce changes in signaling pathways and phenotypic prop-erties.Tangible findings have revealed the pivotal involve-ment of sEVs in the pathogenesis of various diseases.On the bright side,they are rich sources of biomarkers for diag-nosis,prognosis,treatment response,and disease monitor-ing.sEVs have high stability,biocompatibility,targetability,low toxicity,and are immunogenic in nature.Their intrinsic properties make sEVs an ideal delivery vehicle to be loaded with cargo for therapeutic interventions.Liver diseases are a major global health problem.This review aims to focus on the roles and mechanisms of sEVs in the pathogenesis of liver diseases,liver injury,liver failure,and liver can-cer.sEVs are released not only by hepatocytes but also by stromal and immune cells in the microenvironment.Early detection of liver disease determines the chance for cura-tive treatment and high survival of patients.This review focuses on the potential of circulating sEV cargo as specific and sensitive noninvasive biomarkers for the early detection and prognosis of liver diseases.In addition,the therapeutic use of sEVs derived from various cell types is discussed.Al-though sEVs hold promise for clinical applications,there are still challenges to be overcome by further research to bring utilization of sEVs into clinical practice. | Tingmao Xue Judy Wai Ping Yam | 2022 | Journal of Clinical and Translational Hepatology2022，10，6： | 2 |
| 12 | Viscosity behavior of magnetic suspensions in fluid-assisted finishing显示文摘Magnetic fluid-assisted finishing has been verified both theoretically and experimentally as an effective fabrication technology for opti- cal mirrors and lenses.The purpose of this paper is to introduce a novel design of polishing tool and demonstrate the possible applica- tions of this technology.The work includes studying the viscosity of the magnetic suspensions of micrometer-sized Carbonyl iron particles under the influence of a magnetic field.Both the cases of magnetizable suspension with and without abrasive cerium oxide par- ticles are studied for their ensuing polishing effectiveness.Determination of material removal function is conducted using a Wyko Nat1100 interferometer.Experiments to reduce surface roughness with the proposed tool are also performed using a K9 mirror as the work-piece.Results show that the surface accuracy is improved over three times to less than 0.5 nm after two cycles of polishing. | Haobo Cheng Yam Yeung Hang Tong | 2008 | Progress in Natural Science:Materials International2008，18，1： | 2 |
| 13 | Perceived ethics of online retailers and consumer behavioral intentions: The mediating roles of trust and attitude显示文摘 | Yam B. Limbu Marco Wolf Dale Lunsford | 2012 | Journal of Research in Interactive Marketing2012，，2： | 2 |
| 14 | Consumers’ perceptions of online ethics and its effects on satisfaction and loyalty显示文摘 | Yam B. Limbu Marco Wolf Dale L. Lunsford | 2011 | Journal of Research in Interactive Marketing2011，，1： | 2 |
| 15 | Identification of damage locations for plate-like structures using damage sensitive indices: strain modal approach显示文摘 | Y.Y. Li L. Cheng L.H. Yam W.O. Wong | 2002 | Computers and Structures2002，，25： | 2 |
| 16 | Unburned Carbon Loss in Fly Ash of CFB Boilers Burning Hard Coal显示文摘The unburned carbon loss in fly ash of circulating fluidized bed (CFB) boilers, most of which are burning active fuels such as lignite or peat, is normally very low. However, most CFB boilers in China usually burn hard coals such as anthracite and bituminous coal and coal wastes, so the carbon content in the fly ash from these boilers is higher than expected. This paper investigates the source of unburned carbon in the fly ash of CFB boilers burning hard coal through a series of field tests and laboratory investigations. The char behavior during combustion, including fragmentation and deactivation, which is related to the parent coal, has an important impact on the carbon burnout in CFB boilers. The research shows that char deactivation occurs during char burnout in fluidized bed combustion, especially for large particles of low rank coal. The uneven mixing of solids and air in the core region of the furnace also causes poor burnout of carbon in CFB fly ash. An index describing the volatile content (as dry ash free basis) over the heating value is proposed to present the coal rank. The coal combustion efficiency is shown to be strongly connected with this coal index. Several changes in the CFB boiler design are suggested to reduce the unburned carbon loss in the fly ash. | 吕俊复 王启民 黎永 岳光溪 Yam Y.Lee Baldur Eliasson 沈解忠 于龙 | 2003 | Tsinghua Science and Technology2003，8，6： | 2 |
| 17 | Comparison of Dextran Perfusion and GSI-B4 Isolectin Staining in a Mouse Model of Oxygen-induced Retinopathy显示文摘Purpose: Oxygen-induced retinopathy(OIR) is a robust and widely used animal model for the study of retinal neovascularization(NV). Dextran perfusion and Griffonia simplicifolia isolectin B4(GSI-B4) staining are two common methods for examining the occurrence and extent of OIR. This study provides a quantitative comparison of the two for OIR detection.Methods: At postnatal day 7(PN7), fifteen C57 BL / 6J mice were exposed to a 75% hyperoxic condition for 5 days and then returned to room air conditions. At PN17, the mice received intravitreal injection of GSI-B4 Alexa Fluor 568 conjugate. After 10 hours, they were infused with FITC-dextran conjugate via the left ventricle. Retinal flat mounts were photographed by confocal microscopy. Areas with fluorescent signals and the total retinal areas were quantified by Image J software.Results:Both GSI-B4 and dextran detected the peripheral neovascular area. The mean hyper fluorescence area was 0.33 ±0.14% of whole retinal area determined by GSI-B4 staining and 0.25±0.28% determined by dextran perfusion. The difference between the two measures was 0.08%(95% CI:-0.59%,0.43%)..The Pearson correlation coefficient between the two methods was 0.386,P =0.035..The mean coincidence rates were 14.3 ±13.4% and 24.9 ±18.5% for GSI-B4 and dextran staining, respectively.Conclusion:.Both methods can complement each other indemonstrating and quantitatively evaluating retinal NV. A poor agreement was found between the two methods;.GSI-B4 isolectin was more effective than FITC-dextran perfusion in evaluating the extent of retinal NV in a mouse model of OIR. | Shaofen Huang Jiajian Liang Gary Hin-Fai Yam Zhihao Lu Chi Pui Pang Haoyu Chen | 2015 | Eye Science2015，30，2： | 2 |
| 18 | Preface显示文摘Inorganic and Coordination Chemistry is a major branch of chemistry and is an area of growing interest and impor-tance in the chemical community, and in particular, there has been a growing interest in this area owing to the recent rapid developments of coordination chemistry related re- | Vivian Wing-Wah Yam | 2010 | Science China Chemistry2010，53，10： | 2 |
| 19 | Analysis of sources of innovation, technological innovation capabilities, and performance: An empirical study of Hong Kong manufacturing industries显示文摘 | Richard C.M. Yam William Lo Esther P.Y. Tang Antonio K.W. Lau | 2010 | Research Policy2010，，3： | 2 |
| 20 | A reverse dot-blot method for rapid detection of non-deletion alpha thalassaemia显示文摘 | Chan V Yam I Chen FE | | 0，，： | 1 |
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