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| 1 | Acetyl salicylic acid attenuates cardiac hypertrophy through Wnt signaling显示文摘室的肥大是心血管的疾病的事件的一个强大、独立的预言者。低剂量的乙酰水杨酸酸(阿司匹林) 的脉管的性质通过血小板 cyclooxygenase 的不可逆的抑制提供心血管的好处 1;然而,可能的 anti-hypertrophic 性质和阿司匹林的潜在的机制没详细被调查。在这研究,健康野类型的雄的老鼠随机被划分成三个组并且使遭到了到横向的大动脉的收缩(TAC ) 或假冒的操作。操作 TAC 的老鼠与低剂量的阿司匹林的人的等价物被对待(10 mg 吗? | Samuel Chege Gitau Xuelian Li Dandan Zhao Zhenfeng Guo Haihai Liang Ming Qian Lifang Lv Tianshi Li Bozhi Xu Zhiguo Wang Yong Zhang Chaoqian Xu Yanjie Lu Zhiming Du Hongli Shan Baofeng Yang | 2015 | Frontiers of Medicine2015，9，4： | 6 |
| 2 | The FGF21-adiponectin axis in controlling energy and vascular homeostasis显示文摘Whole-body energy metabolism and cardiovascular homeostasis are tightly controlled processes that involve highly coordinated crosstalk among distal organs.This is mainly achieved by a large number of hormones released from each organ.Among them,fibroblast growth factor 21(FGF21)and adiponectin have recently gained considerable attention,since both of them possess multiple profound protective effects against a myriad of cardio-metabolic disorders.Despite their distinct structuresand production sites,these two hormones share striking functional similarity.This dichotomy is recently reconciled by the demonstration of the FGF21-adiponectin axis.In adipocytes,both transcription and secretion of adiponectin are strongly induced by FGF21,which is partially dependent on PPARg activity.Furthermore,the glucose-lowering,lipid-clearing,and anti-atherosclerotic functions of FGF21 are diminished in adiponectin-null mice,suggesting that adiponectin serves as an obligatory mediator of FGF21-elicited metabolic and vascular benefits.However,in both animals and human subjects with obesity,circulating FGF21 levels are increased whereas plasma adiponectin concentrations are reduced,perhaps due to FGF21 resistance,suggesting that dysfunctional FGF21-adiponectin axis is an important contributor to the pathogenesis of obesity-related cardio-metabolic syndrome.The FGF21-adiponectin axis protects against a cluster of cardio-metabolic disorders via mediating multi-organ communications,and is a promising target for therapeutic interventions of these chronic diseases. | Xiaoyan Hui Tianshi Feng Qing Liu Yuan Gao Aimin Xu | 2016 | Journal of Molecular Cell Biology2016，8，2： | 4 |
| 3 | Unveiling the Effects of Interchain Hydrogen Bonds on Solution Gelation and Mechanical Properties of Diarylfluorene-Based Semiconductor Polymers显示文摘The intrinsically rigid and limited strain of most conjugated polymers has encouraged us to optimize the extensible properties of conjugated polymers.Herein,learning from the hydrogen bonds in glucose,which were facilitated to the toughness enhancement of cellulose,we introduced interchain hydrogen bonds to polydiarylfluorene by amide-containing side chains.Through tuning the copolymerization ratio,we systematically investigated their influence on the hierarchical condensed structures,rheology behavior,tensile performances,and optoelectronic properties of conjugated polymers.Compared to the reference copolymers with a low ratio of amide units,copolymers with 30%and 40%amide units present a feature of the shearthinning process that resembled the non-Newtonian fluid,which was enabled by the interchain dynamic hydrogen bonds.Besides,we developed a practical and universal method for measuring the intrinsic mechanical properties of conjugated polymers.We demonstrated the significant impact of hydrogen bonds in solution gelation,material crystallization,and thin film stretchability.Impressively,the breaking elongation for P4 was even up to~30%,which confirmed the partially enhanced film ductility and toughness due to the increased amide groups.Furthermore,polymer light-emitting devices(PLEDs)based on these copolymers presented comparable performances and stable electroluminescence(EL).Thin films of these copolymers also exhibited random laser emission with the threshold as low as 0.52μJ/cm^(2),suggesting the wide prospective application in the field of flexible optoelectronic devices. | Lubing Bai Yamin Han Chen Sun Xiang An Chuanxin Wei Wei Liu Man Xu Lili Sun Ning Sun Mengna Yu He Zhang Qi Wei Chunxiang Xu Yingguo Yang Tianshi Qin Linghai Xie Jinyi Lin Wei Huang | 2020 | Research2020，，1： | 2 |
| 4 | Novel polyacrylonitrile nanoeomposites containing Na-montmorillonite and nano SiO2 particle显示文摘 | Yu Tianshi Lin Jiaping Xu Jiafu | 2005 | Polymer2005，411，15： | 1 |
| 5 | Novel polyacryloni- trile/Na-MMT/siliea nanoeomposite: co-incorporation of two different folan nano materials into polymer matrix显示文摘 | Yu Tianshi Lin Jiaping Xu Jiafu | 2007 | Composites Seienee and Technology2007，67，1516： | 1 |
| 6 | Nanocomposites of vinyl chloride-acrylonitrile copolymer and silica 显示文摘 | Yu Tianshi Lin Jiaping Xu Jiafu | 2005 | Journal of Polymer Science: Part B: Polymer Physics2005，43，： | 1 |
| 7 | Nanocompositcs of vinyl chloride - acrylonitrilc copolymer and silica 显示文摘 | Yu Tianshi Lin Jiaping Xu Jiafu | 2005 | Journal of Polymer Science: Part B: Polymer Physics2005，43，： | 1 |
| 8 | 显示文摘 | Yu Tianshi Lin Jiaping Xu Jiafu | 2005 | Polymer2005，46，： | 1 |
| 9 | Study of acoustic transducer installation effects on ultrasonic flowmeter measurement performance by numerical simulation显示文摘 | Zheng Dandan Zhang Pengyong Xu Tianshi | 2011 | Journal of Mechanical Engineering2011，47，12： | 1 |
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