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| 1 | Injury of cortical neurons is caused by the advanced glycation end products-mediated pathway显示文摘Advanced glycation end products lead to cell apoptosis, and cause cell death by increasing endoplasmic reticulum stress. Advanced glycation end products alone may also directly cause damage to tissues and cells, but the precise mechanism remains unknown. This study used primary cultures of rat cerebral cortex neurons, and treated cells with different concentrations of glycation end products (50, 100, 200, 400 mg/L), and with an antibody for the receptor of advanced glycation end products before and after treatment with advanced glycation end products. The results showed that with increasing concentrations of glycation end products, free radical content increased in neurons, and the number of apoptotic cells increased in a dose-dependent manner. Before and after treatment of advanced glycation end products, the addition of the antibody against advanced glycation end-products markedly reduced hydroxyl free radicals, malondialdehyde levels, and inhibited cell apoptosis. This result indicated that the antibody for receptor of advanced glycation end-products in neurons from the rat cerebral cortex can reduce glycation end product-induced oxidative stress damage by suppressing glycation end product receptors. Overall, our study confirms that the advanced glycation end products-advanced glycation end products receptor pathway may be the main signaling pathway leading to neuronal damage. | Ying Xing Xu Zhang Xiangfu Song Zhongwen Lv Lingling Hou Fei Li | 2013 | Neural Regeneration Research2013，8，10： | 2 |
| 2 | Cloning of a galactose-binding lectin from the venom of Trimeresurus stejnegeri 显示文摘 | Xu Qiang Wu Xiangfu Xia Qichang | 1999 | Biochem J1999，541，3： | 1 |
| 3 | Inhibited Transesterification of PET/PBT Blends Filled with Silica Nanoparticles During Melt Processing显示文摘 | Wang Feng Meng Xiangfu Xu Xinfeng | 2008 | Polymer Degradation and Stability2008，93，： | 1 |
| 4 | Variability in the empirical leucine-to-carbon conversion factors along an environmental gradient显示文摘Bacterial production is one of the key parameters to evaluate bacterial role in ocean carbon fluxes.Estimation of bacterial production requires the leucine-to-carbon conversion factors that change widely across environments.However,empirical leucine-to-carbon conversion factors(e CFs) are seldom determined in situ because of time consuming and little is known on regulating factors for the e CFs.During May 2015 to January 2016,fourteen dilution experiments were conducted,from the Zhujiang(Pearl River) Estuary to the coast of the northern South China Sea,to determine spatiotemporal variability in the e CFs and its potential controlling factors along an environmental gradient.The e CFs showed clear spatial variations with the highest(1.27–1.69(kg C)/(mol Leu)) in low salinity waters(salinity<15),intermediate(1.03–1.25(kg C)/(mol Leu)) in moderate salinity(salinity of 15–25),and the lowest(0.48–0.85(kg C)/(mol Leu)) in high salinity waters(salinity>25).Substrate availability was responsible for spatial variability in the e CFs.In the pristine coastal waters,low e CFs was related to substrate limitation and leucine incorporated was respired to maximize the survival rather than bacterial production.Hence,the e CFs measurement was needed for estimating bacterial production accurately in various marine environments. | LI Xiangfu XU Jie SHI Zhen LI Qian LI Ruihuan | 2018 | Acta Oceanologica Sinica2018，37，4： | 0 |
| 5 | Band Structure in Doubly Odd ~17Ta Nucleus显示文摘BandStructureinDoublyOdd~170TaNucleus￥ZhangYuhu;ZhaoQingzhong;ZhouXiaohong;XuHushan;GuoYinxiang;LeiXiangguo;LuJun;ZhuShaofei;?.. | Zhang Yuhu Zhao Qingzhong Zhou Xiaohong Xu Hushan Guo Yinxiang Lei Xiangguo Lu Jun Zhu Shaofei Huang Wenxue Liu Zhong Gou Quanbu Jin Hanjuan Hu Bitao Luo Yixiao Sun Xiangfu Zhu Yongtai Wen Shukian and Wu Shaoguang (The China Institute of Ato | 1996 | IMP & HIRFL Annual Report1996，，1： | 0 |
| 6 | First principles study of the electronic structure and photovoltaic properties ofβ-CuGaO2 with MBJ+U approach显示文摘Based on the density functional theory,the energy band and electronic structure ofβ-CuGaO2 are calculated by the modified Becke-Johnson plus an on-site Coulomb U(MBJ+U)approach in this paper.The calculated results show that the band gap value ofβ-CuGaO2 obtained by the MBJ+U approach is close to the experimental value.The calculated results of electronic structure indicate that the main properties of the material are determined by the bond between Cu-3 d and O-2p energy levels near the valence band ofβ-CuGaO2,while a weak anti-bond combination is formed mainly by the O-2p energy level and Ga-4 s energy level near the bottom of the conduction band ofβ-CuGaO2.Theβ-CuGaO2 thin film is predicted to hold excellent photovoltaic performance by analysis of the spectroscopic limited maximum efficiency(SLME)method.At the same time,the calculated maximum photoelectric conversion efficiency of the ideal CuGaO2 solar cell is 32.4%.Relevant conclusions can expandβ-CuGaO2 photovoltaic applications. | Guoping Luo Yingmei Bian Ruifeng Wu Guoxia Lai Xiangfu Xu Weiwei Zhang Xingyuan Chen | 2020 | Journal of Semiconductors2020，41，10： | 0 |
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