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| 1 | ENPP1/PC-1 Gene K121Q Polymorphism Is Associated with Obesity in European Adult Populations: Evidence from A Meta-Analysis Involving 24 324 Subjects显示文摘Objective Findings from the previous studies have suggested a relationship between ectonucleotide pyrophosphatase /phosphodiesterase 1 (ENPP‐1) or plasma cell membrane glycoprotein 1 (PC‐1) gene single nucleotide polymorphism (K121Q, rs1044498) and genetic susceptibility to obesity. However, such relationship is not reproduced by some currently available studies. In this context, the present study is aimed to quantitatively analyze the association of K121Q variant with obesity in all published case‐control studies in European adult populations. Methods Published literature from PubMed, EMBASE, and ISI web of science databases were retrieved. The studies evaluating the association of ENPP1/PC1 gene K121Q polymorphism with obesity were included, in which sufficient data were presented to calculate the odds ratio (OR) with 95% confidence intervals (CIs). Results Ten case‐control studies meeting the inclusion criteria identified a total of 24,324 subjects including 11,372 obese and 12,952 control subjects. The meta‐analysis results showed a statistically significant association of K121Q with obesity [OR (95%CI): 1.25 (1.04‐1.52) P=0.021] under a recessive model of inheritance (QQ vs. KK+KQ) without heterogeneity or publication bias. Conclusions The results from the present study have indicated that ENPP1/PC1 Q121 variant may increase the risk of obesity and that more well‐designed studies based on a larger population will be required to further evaluate the role of ENPP1/PC1 gene K121Q polymorphism in obesity and other related metabolic syndromes. | WANG RuoQi ZHOU DongHao XI Bo GE XiuShan ZHU Ping WANG Bo ZHOU MingAi HUANG YuBei LIU JunTing YU Yang WANG ChunYu | 2011 | Biomedical and Environmental Sciences2011，24，2： | 4 |
| 2 | MEC-Assisted Flexible Transcoding Strategy for Adaptive Bitrate Video Streaming in Small Cell Networks显示文摘Adaptive bitrate video streaming(ABR)has become a critical technique for mobile video streaming to cope with time-varying network conditions and different user preferences.However,there are still many problems in achieving high-quality ABR video streaming over cellular networks.Mobile Edge Computing(MEC)is a promising paradigm to overcome the above problems by providing video transcoding capability and caching the ABR video streaming within the radio access network(RAN).In this paper,we propose a flexible transcoding strategy to provide viewers with low-latency video streaming services in the MEC networks under the limited storage,computing,and spectrum resources.According to the information collected from users,the MEC server acts as a controlling component to adjust the transcoding strategy flexibly based on optimizing the video caching placement strategy.Specifically,we cache the proper bitrate version of the video segments at the edge servers and select the appropriate bitrate version of the video segments to perform transcoding under jointly considering access control,resource allocation,and user preferences.We formulate this problem as a nonconvex optimization and mixed combinatorial problem.Moreover,the simulation results indicate that our proposed algorithm can ensure a low-latency viewing experience for users. | Chunyu Liu Heli Zhang Hong Ji Xi Li | 2021 | China Communications2021，18，2： | 2 |
| 3 | Clustering Aggregation by Probability Accumulation显示文摘 | Wang Xi Yang Chunyu Zhou Jie | 2009 | Pattern Recognition2009，42，5： | 1 |
| 4 | Clustering aggregation by probability accumulation显示文摘 | Wang Xi Yang Chunyu Zhou Jie | 2009 | Pattern Recognition2009，42，5： | 1 |
| 5 | Clustering aggregation by probability accumulation显示文摘 | Wang Xi Yang Chunyu Zhou Jie | 2009 | Pattem Recognition2009，42，5： | 1 |
| 6 | Poly- ethylene glycol - stabilized platinum nanoparticles: The eficient and recyclable catalysts for selective hydrogenation of o - chloronitrobenzene to o - ehloroaniline 显示文摘 | Cheng Haiyang Xi Chunyu Meng Xiangchun | 2009 | Journal of Colloid and Interface Science2009，336，： | 1 |
| 7 | Clustering aggrega-tion by probability accumulation显示文摘 | Wang Xi Yang Chunyu Zhou Jie | 2009 | Pattern Recognition2009，42，5： | 1 |
| 8 | Hydrogenation of o-chloronitrobenzene to o-chloroaniline over Pd/C in supererifical carbon dioxide显示文摘 | Xi Chunyu Cheng Haiqyang Hao Jianmin | 2008 | Journal of Molecular Catalysis A! Chemical2008，282，12： | 1 |
| 9 | Clustering aggregation by proba- bility accumulation 显示文摘 | Wang Xi Yang Chunyu Zhou Jie | 2009 | Pattern Recognition2009，42，5： | 1 |
| 10 | High-mobility group protein B1 (HMGB1) is a novel biomarker for human ovarian cancer显示文摘 | Jie Chen Bo Xi Yueran Zhao Yang Yu Jie Zhang Chunyu Wang | 2012 | Gynecologic Oncology2012，，1： | 1 |
| 11 | Clustering aggrega- tion by probability accumulation 显示文摘 | WANG Xi YANG Chunyu ZHOU Jie | 2009 | Pattern recognition2009，42，5： | 1 |
| 12 | Dual non-diffractive terahertz beam generators based on all-dielectric metasurface显示文摘The applications of terahertz(THz)technology can be greatly extended using non-diffractive beams with unique field distributions and non-diffiactive transmission characteristics.Here,we design and experimentally demonstrate a set of dual non-diffractive THz beam generators based on an all-dielectric metasurface.Two kinds of non-diffractive beams with dramatically opposite focusing properties,Bessel beam and abruptly autofocus-ing(AAF)beam,are considered.A Bessel beam with longdistance non-diffractive characteristics and an AAF beam with low energy during transmission and abruptly increased energy near the focus are generated for x-and^-polarized incident waves,respectively.These two kinds of beams are characterized and the results agree well with simulations.In addition,we show numerically that these two kinds of beams can also carry orbital angular momentum by further imposing proper angular phases in the design.We believe that these metasurface-based beam generators have great potential use in THz imaging,communications,non-destructive evaluation,and many other fields. | Chunyu LIU Yanfeng LI Xi FENG Xixiang ZHANG Jiaguang HAN Weili ZHANG | 2021 | Frontiers of Optoelectronics2021，14，2： | 1 |
| 13 | Deletion of large-conductance calcium-activated potassium channels promotes vascular remodelling through the CTRP7-mediated PI3K/Akt signaling pathway显示文摘The large-conductance calcium-activated potassium(BK)channel is a critical regulator and potential therapeutic target of vascular tone and architecture,and abnormal expression or dysfunction of this channel is linked to many vascular diseases.Vascular remodelling is the early pathological basis of severe vascular diseases.Delaying the progression of vascular remodelling can reduce cardiovascular events,but the pathogenesis remains unclear.To clarify the role of BK channels in vascular remodelling,we use rats with BK channelαsubunit knockout(BKα‒/‒).The results show that BKα‒/‒rats have smaller inner and outer diameters,thickened aortic walls,increased fibrosis,and disordered elastic fibers of the aortas compared with WT rats.When the expression and function of BKαare inhibited in human umbilical arterial smooth muscle cells(HUASMCs),the expressions of matrix metalloproteinase 2(MMP2),MMP9,and interleukin-6 are enhanced,while the expressions of smooth muscle cell contractile phenotype proteins are reduced.RNA sequencing,bioinformatics analysis and qPCR verification show that C1q/tumor necrosis factor-related protein 7(CTRP7)is the downstream target gene.Furthermore,except for that of MMPs,a similar pattern of IL-6,smooth muscle cell contractile phenotype proteins expression trend is observed after CTRP7 knockdown.Moreover,knockdown of both BKαand CTRP7 in HUASMCs activates PI3K/Akt signaling.Additionally,CTRP7 is expressed in vascular smooth muscle cells(VSMCs),and BKαdeficiency activates the PI3K/Akt pathway by reducing CTRP7 level.Therefore,we first show that BK channel deficiency leads to vascular remodelling.The BK channel and CTRP7 may serve as potential targets for the treatment of cardiovascular diseases. | Jing Bi Yanru Duan Meili Wang Chunyu He Xiaoyue Li Xi Zhang Yan Tao Yunhui Du Huirong Liu | 2022 | Acta Biochimica et Biophysica Sinica2022，54，12： | 0 |
| 14 | Graphene Supported Platinum Nanoparticles as Catalyst for Oxygen Reduction Reaction显示文摘 | ZHANG Wenyu WANG Zhixin SHEN Yan XI Muyao CHU Xuebin XI Chunyu | 2015 | Chemical Research in Chinese Universities2015，31，6： | 0 |
| 15 | The HIF-1A/miR-17-5p/PDCD4 axis contributes to the tumor growth and metastasis of gastric cancer显示文摘Dear Editor,Gastric cancer(GC)is one of the most common malignant tumors of the digestive system and the second leading cause of cancer death worldwide1.Despite the gradually declining morbidity and mortality,GC still burdens many countries in East Asia1.Understanding the GC pathological process is vital for the successful diagnosis,treatment and prevention of this disease. | Jiayu Zhao Anqi Xiao Chunyu Liu Chao Ye Kai Yin Minghon Lu Ruihua Jiao Xi Chen Chenyu Zhang Minghui Liu | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 0 |
| 16 | Report and Phylogeny of a Novel Euplotes Species from China:E.mazeii n.sp.,and Review of E.balteatus(Alveolata,Ciliophora)显示文摘The freshwater species,Euplotes mazeii n.sp.,and the marine species,E.balteatus(Dujardin,1841)Diesing,1850 were collected from China and investigated based on their living morphology,ciliary pattern,and small subunit ribosomal RNA(SSU rRNA)gene sequence data.Euplotes mazeii n.sp.was characterized by its small cell size((40-55)μm×(25-35)μm),nine frontoventral cirri,one marginal and two caudal cirri,seven dorsal kineties,and a double-eurystomus type of dorsal silverline system.Phylogenetic analyses based on molecular data confirmed the branching position of this new taxa within the genus Euplotes,with 5.01%(84 nucleotides)sequence variation,supporting the identification of a new species.We re-examined all described and supposedly conspecific populations and give a review of Euplotes balteatus.E.balteatus has been reported frequently;however,E.balteatus sensu Agamaliev,1968 is different from other populations in the number of marginal cirri or the type of silverline system,which suggests there might be a misidentification.The SSU rRNA gene sequences of two populations of E.balteatus from the studies of Chen et al.(2013)and Pan et al.(2012)differ from each other by more than 135 nucleotides,implying that the identity of the species currently associated with the SSU rRNA gene sequence in molecular databases requires further confirmation. | LIAN Chunyu JIANG Jiamei XI Muchen DONG Jingyi MA Honggang AL-FARRAJ Saleh A STOECK Thorsten WANG Chundi SHAO Chen | 2023 | Journal of Ocean University of China2023，22，3： | 0 |
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