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| 1 | Aminoglycoside-induced and non-syndromic hearing loss is associated with the G7444A mutation in the mitochondrial COI/tRNA (Ser(UCN)) genes in two Chinese families显示文摘 | Zhu Y Qian YP Tang XW Wang JD Yang L Liao ZS Li RH Ji JZ Li ZY Chen JF Choo DI Lu JX Guan MX | 2006 | 中国生物学文摘2006，20，4： | 16 |
| 2 | Induction of mucosal and systemic immune response by single-dose oral immunization with biodegradable microparticles containing DNA encoding HBsAg显示文摘 | He XW Wang F Jiang L Li J Liu SK Xiao ZY Jin XQ Zhang YN He Y Li K Guo YJ Sun SH | 2005 | 第二军医大学学报2005，26，10： | 5 |
| 3 | Effect of Selenium Supplementation on Activity and mRNA Expression of Type 1 Deiodinase in Mice With Excessive Iodine Intake显示文摘Objective To investigate the effect of selenium supplementation on the selenium status and selenoenzyme, especially the activity and mRNA expression of type 1 deiodinase (D1) in mice with excessive iodine (EI) intake and to explore the mechanism of selenium intervention on iodine-induced abnormities. Methods Weanling female BALB/c mice were given tap water or 3 mg/L of iodine or supplemented with 0.5 mg/L or 1.0 mg/L of selenium in the presence of excessive iodine for 5 months. Selenium status, thyroid hormone level, hepatic and renal D1 activity and mRNA expression were examined. Results Excessive iodine intake significantly decreased the selenium concentration in urine and liver, and the activity of glutathione peroxidase (GSH-Px) in liver. Meanwhile, serum total T4 (TT4) increased while serum total T3 (TT3) decreased. Hepatic D1 enzyme activity and mRNA expression were reduced by 33% and 86%, respectively. Renal D1 enzyme activity and mRNA were reduced by 30% and 55%, respectively. Selenium supplementation obviously increased selenium concentration, activity of GSH-Px and D1 as well as mRNA expression of D1. However, increasing the supplementation of Se from 0.5 to 1.0 mg/L did not further increase selenoenzyme activity and expression. Conclusion Relative selenium deficiency caused by excessive iodine plays an essential role in the mechanism of iodine-induced abnormalities. An appropriate dose of selenium supplementation exercises a beneficial intervention. | XUE-FENG YANG XIAO-HUI HOU JIAN XW HUAI-LAN GUO CHEN-JIANG YING XIAO-YI CHEN XIU-FA SUN | 2006 | Biomedical and Environmental Sciences2006，19，4： | 5 |
| 4 | A class of irregular wavelet frames显示文摘THE inner product <f, g> of f and g in L2 (R) is defined by <f, g>, and is the norm of f ; moreover, dx is the Fourier transform of f. ForΩ>O, we | Zhou, XW Li, YQ | 1997 | Chinese Science Bulletin1997，42，17： | 4 |
| 5 | Large scale identification of human hepatocellular carcinoma- associated antigens by autoantibodies显示文摘 | Wang Y Han KJ Pang XW | 2002 | J Immunol2002，169，2： | 3 |
| 6 | Determination and geological implication of O-Si isotope of the sediment core in the CC area, the Pacific Ocean显示文摘ONCE ocean floor was below the calcite compensation depth (CCD), deeper than 5000 m, it was widely covered with siliceous ooze or abyssal clay without abyssoconite. The samples of sediment core used in the present research were collected at No. 1787 station during DY85-04 cruise and are mostly of siliceous ooze or abyssal clay. Therefore, traditional and well-considered stable isotopic study using foraminifera has to be given up. Instead, stable isotopic | Wu, SY Ding, TP Meng, XW Bai, LM | 1997 | Chinese Science Bulletin1997，42，17： | 3 |
| 7 | Laparoscopic wedge resection of synchronous gastric intraepithelial neoplasia and stromal tumor:A case report显示文摘Synchronous occurrence of epithelial neoplasia and gastrointestinal stromal tumor(GIST)in the stomach is uncommon.Only rare cases have been reported in the literature.We present here a 60-year-old female case of synchronous occurrence of gastric high-level intraepithelial neoplasia and GIST with the features of 22 similar cases and detailed information reported in the Englishlanguage literature summarized.In the present patient,epithelial neoplasia and GIST were removed en bloc by laparoscopic wedge resection.To the best of our knowledge,this is the first reported case treated by laparo-scopic wedge resection. | Mou YP Xu XW Xie K Zhou W Zhou YC Chen K. | 2010 | World Journal of Gastroenterology2010，16，39： | 2 |
| 8 | P53 based blood test for P53 PIN3 and risk for sporadic ovarian cancer显示文摘 | Runnenbaum IB Tong XW Konig R | 1995 | Lancet1995，354，： | 2 |
| 9 | 农村和城市健康信息获取与利用的差异显示文摘与城市居民相比,农村居民对某些健康信息的获取和利用可能较少。本研究调查了美国农村和城市成年人在获取和利用信息方面的差异,以及低健康素养是否会加剧农村居民在获取和利用健康信息方面的差异。600名调查对象(其中50%来自农村)完成了关于25个健康信息的获取和利用情况的在线调查,使用logistic回归模型检验农村居民与健康信息的获取和利用之间的关系,农村与健康素养之间是否存在交互作用,以预测健康信息的获取和利用情况。研究发现与城市居民相比,农村居民从初级保健提供者、专科医生、博客和杂志以及等渠道获取健康信息的机会更少,使用搜索引擎的机会也更少。在考虑了社会人口统计学因素后,农村居民从专科医生这个渠道获取健康信息的比例低于城市居民。健康素养有限的农村居民获得大众媒体和科学文献的机会较低,但无论健康素养水平如何,对制药企业/公司的使用率高于健康素养充足的农村居民和城市居民。农村和城市人口在获取和利用健康信息方面的一些差异可能是由社会人口学差异造成的。可能存在结构性障碍,如缺乏专科医生以及和媒体接触有限的原因,使农村居民尤其是健康素养有限的居民更难获得健康信息。 | Chen XW Orom H Jennifer LH 王坤(编译) | 2020 | 中华预防医学杂志2020，54，1： | 2 |
| 10 | Preparative separation and determination of matrine from the chinese medicinal plant Sophora flavescens air by molecularly imprinted solid phase extraction显示文摘 | Lai JP He XW Jiang Y | | 0，，02： | 2 |
| 11 | Homocysteine enhances neutrophil- endothelial interactions in both cultured human cells and ratsin vivo 显示文摘 | Dudman NP Temple SE Guo XW | 1999 | Circulation Research1999，84，4： | 1 |
| 12 | Laparoscopically assisted sigmoid colon vaginoplasty in women Mayer-Rokitansky-Kuster- Hauser syndrome: feasibility and short-term results 显示文摘 | Cai B Zhang JR Xi XW | 2007 | BJOG2007，114，： | 1 |
| 13 | Value of serum glycated albumin and high-sensitivity C-reactive protein levels in the prediction of presence of coronary artery disease in patients with type 2 diabetes显示文摘 | Pu LJ Lu L Xu XW | 2006 | Cardiovasc Diabetol2006，20，5： | 1 |
| 14 | Alu-directed transcriptional regulation of some novel miRNAs显示文摘 | Gu TJ Yi X Zhao XW | 2009 | BMC Genomics2009，10，： | 1 |
| 15 | Physical and intellectual development in children with asymptomatic congenital cytomegalovirus infection:A longitudinal cohort study in Qinba mountain area,China显示文摘 | ZHANG XW LI F YU XW | 2007 | J Clin Virol2007，40，3： | 1 |
| 16 | A novel mutation of-73(A→T)in theCCAAT box of theβ-globin gene identified in a patient with the mildβ-thalassemia intermedia显示文摘 | Chen XW Mo QH Li Q | 2007 | Ann Hematol2007，86，9： | 1 |
| 17 | Tetanic contractions impair sar-comeric Z-disk of atrophic soleus muscle via calpain pathway显示文摘 | MA XW LIQ XU PT | 2011 | Mol Cell Biochem2011，354，12： | 1 |
| 18 | Attenuation of microRNA-1derepresses the cy-toskeleton regulatory protein twinfilin-1to provoke cardiac hypertrophy显示文摘 | Li Q Song XW Zou J | 2010 | J Cell Sci2010，123，： | 1 |
| 19 | Soluble TGF-β type Ⅱ receptor gene therapy ameliorates acute radiation-induced pulmonary injury in rats 显示文摘 | Rabbani ZN Anscher MS Zhang XW | 2003 | Int J Radiat Oncol Biol Phys2003，57，2： | 1 |
| 20 | Human homocysteine catabolism:three major patheays and their relevance to development of arterial occlusive disease显示文摘 | Dudman NPB Guo XW Gordon RB | 1996 | J Nutr1996，126，： | 1 |
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