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| 1 | A new bone repair scaffold combined with chitosan/ hydroxyapatite and sustained releasing icariin显示文摘Icariin, a plant-derived flavonol glycoside, has been proved as an osteoinductive agent for bone tissue engineering. A new bone repair scaffold was generated by thorough mixing of icariin and chitosan/ hydroxyapatite (icariin-CS/HA) using freeze-drying technigue. Characteristics of morphology, mechanical properties, biocompatibility, drug release behavior and bone repair abilities in vivo were evaluated. The results show that drug loading process of icariin did not affect physical structure of CS/HA composite significantly but decreased mechanical properies of CS/HA composite, which happened with a high dosage; icariin-CS/HA had favorable cell compatibility and promoted osteogenic differentiation of hBMSCs; the controlled release of icariin was satisfactory and the release retained after 90 d in vitro. In addition, icariin-CS/HA scaffolds had favorable osteoconduction and osteoinduction in vivo, and could fill bone defect sites and stimulate newborn bone tissues formation at early stage. On the basis of these data, icariin-CS/HA is believed to be an optical bone repair scaffold for tissue engineering. | WU Tao NAN KaiHui CHEN JingDi JIN Dan JIANG Shan ZHAO PeiRan XU JunChang DU Hao ZHANG XiaoQiang LI JianWei PEI GuoXian | 2009 | Chinese Science Bulletin2009，54，17： | 14 |
| 2 | A New Darwinopterid Pterosaur from the Middle Jurassic of Western Liaoning,Northeastern China and its Ecological Implications显示文摘Darwinopterus 的新种, D。robustodens sp。nov。被描述并且说出。基于新标本, Darwinopterus 的诊断人物被修改并且包括:喙的出牙好空间的、穗状的牙齿创作了;最长的牙齿被限制到牙齿排的前面的一半;牙齿 alveoli 提起了边缘;nasoantorbital 窗汇合;倾向适合;伸长有低神经脊骨的颈的 vertebrae 并且减少或不在的肋骨;超过 20 caudals 的长尾巴部分由 pre- 和 postzygapophyses 的丝状的延期围住;短掌肱骨的不到 60% 长度,有二的第五个脚趾伸长指骨和有在近似、远侧的片断之间的角度的第五个脚趾的弄弯的秒踏脚板方阵大约 130 度。新翼龙 D 的完全的标本。robustodens sp。nov。提供更骨学的信息。在在 Darwinopterus modularis 和 D 之间的牙齿形态学的差别。robustodens sp。nov。建议他们充满了不同生态的壁龛。努力忍受覆盖物的翘目可以是 Darwinopterus robustodens 的主要食物来源。 | Lu Junchang XU Li CHANG Huali ZHANG Xingliao | 2011 | Acta Geologica Sinica(English Edition)2011，85，3： | 13 |
| 3 | Distributed and Weighted Extreme Learning Machine for Imbalanced Big Data Learning显示文摘The Extreme Learning Machine(ELM) and its variants are effective in many machine learning applications such as Imbalanced Learning(IL) or Big Data(BD) learning. However, they are unable to solve both imbalanced and large-volume data learning problems. This study addresses the IL problem in BD applications. The Distributed and Weighted ELM(DW-ELM) algorithm is proposed, which is based on the Map Reduce framework. To confirm the feasibility of parallel computation, first, the fact that matrix multiplication operators are decomposable is illustrated.Then, to further improve the computational efficiency, an Improved DW-ELM algorithm(IDW-ELM) is developed using only one Map Reduce job. The successful operations of the proposed DW-ELM and IDW-ELM algorithms are finally validated through experiments. | Zhiqiong Wang Junchang Xin Hongxu Yang Shuo Tian Ge Yu Chenren Xu Yudong Yao | 2017 | Tsinghua Science and Technology2017，22，2： | 8 |
| 4 | Largest Toothed Pterosaur Skull from the Early Cretaceous Yixian Formation of Western Liaoning, China, with Comments on the Family Boreopteridae显示文摘A new pterosaur Moganopterus zhuiana gen. et sp. nov. is erected based on a complete skull with lower jaws and anterior cervical vertebrae. It is characterized by much elongated upper and lower jaws with at least 62 total, long, curved teeth with sharp tips, a well developed parietal crest extending posterodorsally, forming an angle of 15 degrees with the ventral margin of the skull, the ratio of length to width of cervical vertebrae greater than 5:1. The skull length is 750 mm, and it is the largest toothed pterosaur found so far in the world. Based on this new pterosaur, the Boreopteridae can be divided into two subgroups: Boreopterinae sub-fam. nov. and Moganopterinae sub-fam. nov., which is also confirmed by the phylogenetic analysis. | LU Junchang PU Hanyong XU Li WU Yanhua WEI Xuefang | 2012 | Acta Geologica Sinica(English Edition)2012，86，2： | 6 |
| 5 | A New Oviraptorid Dinosaur (Theropoda: Oviraptorosauria) from the Late Cretaceous of Jiangxi Province, Southern China显示文摘A new oviraptorid dinosaur Jiangxisaurus ganzhouensis gen. et sp. nov., is erected based on a partial skeleton from the Upper Cretaceous Nanxiong Formation of Ganzhou City, Jiangxi Province. The new taxon differs from other oviraptorids in the weakly downturned rostrum of the lower jaw, much-elongated mandible with a height-to-length ratio being about 20% and the length ratio of radius to humerus of about 0.70. This species not only adds a new member to oviraptorid dinosaurs, but also provides more information about oviraptorid paleogeographical distribution in southern China. | WEI Xuefang PU Hanyong XU Li LIU Di Lü Junchang | 2013 | Acta Geologica Sinica(English Edition)2013，87，4： | 6 |
| 6 | A New Sauropod Dinosaur from the Late Cretaceous Gaogou Formation of Nanyang,Henan Province显示文摘一张新 sauropod 恐龙 Baotianmansaurus henanensis 情报。et sp。nov。从 Neixiang 的白垩纪 Gaogou 形成,河南省省被树立。它被 somphospondylous presacral vertebrae 描绘;背面的 vertebrae 上的一个高度开发的薄板系统;横向的过程由四个薄片支持了;并且前面的 centroparapophyseal 薄板的背面的部分被区分,与延长到 prezygapophysis 的腹的表面的一个小分支。它代表新 titanosauriform sauropod。 | ZHANG Xingliao Lǔ Junchang XU Li LI Jinhua YANG Li HU Weiyong JIA Songhai JI Qiang ZHANG Chengjun | 2009 | Acta Geologica Sinica(English Edition)2009，83，2： | 5 |
| 7 | In vitro effects of sodium hyaluronate on the proliferation and the apoptosis in chondrocytes from patients with Kashin-Beck disease and osteoarthritis显示文摘Objective:To identify the in vitro effects of sodium hyaluronate(HA) on the proliferation and the apoptosis of chondrocytes from patients with Kashin-Beck disease(KBD) and osteoarthritis(OA). Methods:Samples of articular cartilages from KBD and OA patients, as well as healthy volunteers(6 subjects in each of the 3 groups) were dissected, digested with collagenase and the cells cultured in monolayers. Chondrocytes from each sample were assigned to an untreated group and two HA-treated groups: H0(no HA), H100(HA, 0.1 g/L) and H500(HA, 0.5 g/L). The first passage chondrocytes were used to observe proliferation using the MTT assay, and apoptosis by flow cytometry through Annexin V/PI staining. Results:HA promoted proliferation of chondrocytes in all the three groups, and in KBD and OA groups, for cells cultured for 4 and 6 days, H500 significantly promoted the cell proliferation. The apoptotic rates of both KBD and OA group chondrocytes were in the order H500 < HA100 < H0. Conclusion:Sodium hyaluronate administration has a dose-dependent in vitro effect to promote proliferation and inhibit apoptosis of chondrocytes from patients with KBD and OA. | Zongqiang Gao Xiong Guo Chen Duan Weijuan Ma Peng Xu Ruiyu Liu Qisheng Gu Junchang Chen | 2009 | Journal of Nanjing Medical University2009，23，2： | 5 |
| 8 | Description and Phylogenetic Position of Dinosaur Eggshells from the Luanchuan Area of Western Henan Province,China显示文摘这里,我们在西方的河南省省在 Luanchuan 区域的 Qiupa 形成(上面的白垩纪) 从一个新石块地区检验 145 恐龙蛋壳,中国。蛋壳显示 elongatoolithid 宏 -- 并且外部表面,二 ultrastructural 层和连续的层上的微观结构,包括的山脉和节点。系统发生的分析证明 Luanchuan 蛋壳属于 ooclade Elongatoolithidae。在 Elongatoolithidae,到全部蛋壳的 mammillary 层的厚度比率,和 Luanchuan 的孔以内,蛋壳比得上 oogenera Macroolithus 和 Elongatoolithus。为 Luanchuan 蛋壳的分类身份没有直接证据;然而,他们被 oviraptorids 多半与已知的 oviraptorid 鸡蛋基于他们的种系发生的位置和他们的类似生。 | Kohei TANAKA LU Junchang Yoshitsugu KOBAYASHI Darla K. ZELENITSKY XU Li JIA Songhai QIN Shuang TANG Min' an | 2011 | Acta Geologica Sinica(English Edition)2011，85，1： | 3 |
| 9 | Dinosaur-bearing strata and K/T boundary in the Luanchuan-Tantou Basin of western Henan Province,China显示文摘The sequence stratigraphy and geochronology of the terrestrial dinosaur-bearing strata,i.e.,the Qiupa Formation,were poorly studied in the Luanchuan-Tantou Basin in western Henan,China.This study shows that these strata represent a complete succession from the Late Cretaceous to the early Paleogene,including the K/T boundary,in this area.Here we report a detailed study of the K/T boundary,especially its stratigraphic sequence,sedimentary characteristics,integrity,continuity,and geological implications. | JIANG XiaoJun LIU YongQing JI ShuAn ZHANG XingLiao XU Li JIA SongHai LO JunChang YUAN ChongXi LI Ming | 2011 | Science China Earth Sciences2011，54，8： | 3 |
| 10 | A New Lizard(Lepidosauria:Squamata) from the Upper Cretaceous of Henan,China显示文摘Funiusaurus luanchuanensis gen.et sp.nov.was described on the basis of an incomplete skull from the Upper Cretaceous Qiupa Formation of the Tantou Basin in Luanchuan County,Henan Province.It is the second representative of lizards known from Luanchuan and adds a new member to the Luanchuan Fauna.F.luanchuanensis is a small-sized lizard and systematically assigned to the Polyglyphanodontidae of the Teiioidea because of the presence of a caniniform tooth and an elongate posterior process of the postorbital.It is distinctive in that the heterodont dentition bears 19 teeth in both the upper and lower jaws,the 3rd maxillary tooth is large and caniniform,the post-caniniform teeth in maxilla and those posterior to the 3rd dentary tooth are chisel-like in lateral view,the prefrontal possesses a fossa on its lateral surface,the postorbital with an extremely elongate posterior process and the well-developed retroarticular process has a deep fossa on its dorsal surface.In phylogeny,our analysis suggests a close relationship of Funiusaurus to the large-sized Tianyusaurus from the same basin within the Tuberocephalosaurinae.The discovery of Funiusaurus is significant in confirming the status of the Tuberocephalosaurinae,which includes a group of the Asian members of the Polyglyphanodontidae only. | XU Li WU Xiaochun Lü Junchang JIA Songhai ZHANG Jiming PU Hanyong ZHANG Xingliao | 2014 | Acta Geologica Sinica(English Edition)2014，88，4： | 2 |
| 11 | A new azhdarchoid pterosaur from the Lower Cretaceous of China and its implications for pterosaur phylogeny and evolution显示文摘 | Junchang Lü David M. Unwin Li Xu Xingliao Zhang | 2008 | Naturwissenschaften2008，，9： | 1 |
| 12 | Liquid-like polymer lubricating surfaces:Mechanism and applications显示文摘Liquid-like polymer lubricating surfaces(LPLSs)are solid substrates with highly flexible polymer chains grafted via covalent bonds.This unique modification enables ultralow contact-angle hysteresis,repellency of various liquids and bulk ice,and stability.The distinctive wettability and universality of LPLSs have potential applications in liquid motion,biological detection,and environmental protection.In this review,we summarize the mechanisms,preparation,and applications of LPLSs.We discuss the wettability and lubrication mechanisms of liquid droplets on LPLSs.We then categorize LPLS fabrication into“grafted onto”and“grafted from”groups,depending on the type of polymer.We highlight representative applications with recent developments in anti-complex liquid,anti-icing,anti-biological adhesions,biosensing,and photocatalytic activity.Finally,we discuss future challenges and outlooks for LPLSs. | Dagui Wang Jinglong Yang Junchang Guo Zhijuan Duan Deihui Wang Fan Xia Fei Deng Xu Deng | 2024 | Nano Research2024，17，2： | 1 |
| 13 | A new azhdarchoid pterosaur from the Lower Cretaceous of China and its implications for pterosaur phylogeny and evolution显示文摘 | Junchang Lü David M. Unwin Li Xu Xingliao Zhang | 2008 | Naturwissenschaften2008，，9： | 1 |
| 14 | Engineering multifunctional bioadhesive powders through dynamic metal-ligand coordination显示文摘Bioadhesive gels with robust adhesion on wet and irregular tissue surfaces are desirable for clinical applications.Assembly of bioadhesive powders is an effective strategy for obtaining gels that adhere to wet and irregular tissue surfaces by absorbing interfacial water.However,current bioadhesive powders lack positive biological functions and are prone to postoperative adhesion.Here,we present a powder strategy based on metal-ligand coordination to create a series of bioadhesive polyacrylic acid(PAA)gels.In the gel network,metal ions(M^(n+))are used to coordinate with the carboxy ligands of PAA to form dynamic noncovalent crosslinks.The powders can absorb interfacial water and assemble into gels on wet and irregular tissue surfaces within a few seconds,forming an initial adhesion layer by electrostatic interactions.Furthermore,the polymers can diffuse into the tissue matrix,and metal-ligand coordination is reconstructed to enhance the adhesion.Moreover,with a cationic shield layer,the bioadhesive powders can effectively avoid postoperative adhesion.Importantly,M^(n+) ions endow the gel with customized biological functions.We demonstrate that the hemostatic,antibacterial,peroxidase-like catalytic,and photodetachment abilities of the gels by incorporating different M^(n+) ions.These advantages make the bioadhesive powder a promising platform for diverse tissue repair applications. | Junchang Guo Yue Hou Liansong Ye Junnan Chen Hong Wang Li Yang Jinbo Jiang Qiangqiang Sun Chaoming Xie Bing Hu Jiaxi Cui Xu Deng | 2022 | Science China Chemistry2022，65，11： | 0 |
| 15 | Amyloid precursor-like protein 2 C-terminal fragments upregulate S100A9 gene and protein expression in BV2 cells显示文摘The murine microglial cell line BV2 has neuroprotective effects, but is toxic to neurons by secreting inflammatory cytokines, and is an important target in the treatment of nerve inflammation and neurodegenerative diseases. In the present study, we observed the effects of transfecting three amyloid precursor-like protein 2(APLP2) C-terminal fragments(CTFs; C57, C50 and C31) in the p EGFP-N1 vector on S100A9 expression in BV2 cells. Reverse transcription-PCR, western blot assay and immunocytochemistry revealed that S100A9 protein and m RNA expression was greater in BV2 cells after CTF transfection than after mock transfection with an empty vector. Furthermore, transfection of full-length APLP2-751 resulted in low levels of S100A9 protein expression. Our results show that APLP2-CTFs upregulate S100A9 protein and m RNA expression in BV2 cells, and identify a novel pathway involved in neuronal injury and apoptosis, and repair and protection in Alzheimer's disease. | Guangzhe Li Hui Chen Lin Cheng Rongjie Zhao Junchang Zhao Yanji Xu | 2014 | Neural Regeneration Research2014，9，21： | 0 |
| 16 | Screening of New High Quality and High Yield Sweet Potato Varieties in Zaozhuang of Shandong Province显示文摘[Objectives]To compare the growth period,dry matter content and yield of 12 different sweet potato varieties,so as to screen out new sweet potato varieties with high yield,high quality and high dry matter content suitable for cultivation in Zaozhuang of Shandong Province.[Methods]Field random arrangement,three replicates,and field observation were adopted,and data were surveyed and summarized.[Results]There were significant differences in the maturity period between varieties.Longshu 9,Hongxiangjiao,Sushu 8,Yanshu 25,and Yanshu 0747 in the fresh eating group were mature earlier,and Yuzi 7 was mature later;Xushu 32 in the starch group was mature earlier,while Xushu 22(ck),Shangshu 19,Jishu 25,and Jishu 98 had moderate maturity period,and Jixu 23 was mature later.The difference in the yield between the fresh eating group and the starch group reached a very significant level.In the fresh eating group,Yanshu 25 had the highest yield,followed by Longshu 9,and then Yanshu 0747;in the starch group,Jishu 98 had the highest yield,followed by Shangshu 19,and then Jixu 23.Besides,there were significant differences in the dry matter content between varieties.In the fresh eating group,Yuzi 7 had the highest dry matter content(30.4%),followed by Yanshu 25(28.1%),and then Yanshu 0747(28.1%);in the starch group,Xushu 32 had the highest dry matter content(33.6%),followed by Jishu 25(32%),and then Jishu 98(31.5%).[Conclusions]Combining the maturity period,yield,dry matter content,appearance,taste and unique ecological conditions in Zaozhuang area,the varieties suitable for cultivation in Zaozhuang area were screened:in the fresh eating group,it was Yanshu 25 and Longshu 9;in the starch group,it was Jishu 98,Shangshu 19,and Jixu 23. | Jie XU Jialiang LI Junchang LIANG | 2021 | Asian Agricultural Research2021，13，12： | 0 |
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