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| 1 | Inhibitory effect of recombinant adenovirus carrying melittin gene on hepatocellular carcinoma显示文摘 | Ling CQ Li B Zhang C Zhu DZ Huang XQ Gu W Li SX | 2005 | 第二军医大学学报2005，26，10： | 30 |
| 2 | Transjugular intrahepatic portosystemic shunt vs endoscopic therapy in preventing variceal rebleeding显示文摘AIM:To compare early use of transjugular intrahepatic portosystemic shunt(TIPS) with endoscopic treatment(ET) for the prophylaxis of recurrent variceal bleeding.METHODS:In-patient data were collected from 190 patients between January 2007 and June 2010 who suffured from variceal bleeding.Patients who were older than 75 years;previously received surgical treatment or endoscopic therapy for variceal bleeding;and complicated with hepatic encephalopathy or hepatic cancer,were excluded from this research.Thirty-five cases lost to follow-up were also excluded.Retrospective analysis was done in 126 eligible cases.Among them,64 patients received TIPS(TIPS group) while 62 patients received endoscopic therapy(ET group).The relevant data were collected by patient review or telephone calls.The occurrence of rebleeding,hepatic encephalopathy or other complications,survival rateand cost of treatment were compared between the two groups.RESULTS:During the follow-up period(median,20.7 and 18.7 mo in TIPS and ET groups,respectively),rebleeding from any source occurred in 11 patients in the TIPS group as compared with 31 patients in the ET group(Kaplan-Meier analysis and log-rank test,P = 0.000).Rebleeding rates at any time point(6 wk,1 year and 2 year) in the TIPS group were lower than in the ET group(Bonferroni correction α' = α/3).Eight patients in the TIPS group and 16 in the ET group died with the cumulative survival rates of 80.6% and 64.9%(Kaplan-Meier analysis and log-rank test c2 = 4.864,P = 0.02),respectively.There was no significant difference between the two groups with respect to 6-wk survival rates(Bonferroni correction α' = α/3).However,significant differences were observed between the two groups in the 1-year survival rates(92% and 79%) and the 2-year survival rates(89% and 64.9%)(Bonferroni correction α' = α/3).No significant differences were observed between the two treatment groups in the occurrence of hepatic encephalopathy(12 patients in TIPS group and 5 in ET group,KaplanMeier analysis and log-rank test,c2 = 3.103,P = 0.08).The average total cost for the TIPS group was higher than for ET group(Wilcxon-Mann Whitney test,52 678 RMB vs 38 844 RMB,P < 0.05),but hospitalization frequency and hospital stay during follow-up period were lower(Wilcxon-Mann Whitney test,0.4 d vs 1.3 d,P = 0.01;5 d vs 19 d,P < 0.05).CONCLUSION:Early use of TIPS is more effective than endoscopic treatment in preventing variceal rebleeding and improving survival rate,and does not increase occurrence of hepatic encephalopathy. | Hui Xue Meng Zhang Jack XQ Pang Fei Yan Ying-Chao Li Liang-Shan Lv Jia Yuan Muna Palikhe Wei-Zhi Li Zhi-Lun Wang | 2012 | World Journal of Gastroenterology2012，18，48： | 17 |
| 3 | Curcumin protects PC12 cells against 1-methyl-4-phenylpyridinium ion-induced apoptosis by bcl-2-mitochondria-ROS-iNOS pathway.显示文摘 | Chert J Tang XQ Zhi JL Cui Y Yu HM Tang EH Sun SN Feng JQ Chen PX Chen J | 2006 | 中国生物学文摘2006，20，10： | 16 |
| 4 | 中国在2100年前消除子宫颈癌的预算优化策略研究显示文摘2018年,世界卫生组织总干事公布了全球消除子宫颈癌的目标,即发病率降至4/10万以下。中国目前人群人乳头瘤病毒(HPV)疫苗接种率和宫颈癌筛查覆盖率均较低,子宫颈癌发病率以年均10.2%的速度增长。本研究开发了一种适应中国人群并经校准的杂交模型,在预测老龄化、城市化和性行为可能改变的趋势下,估计2015—2100年城市和农村每年的子宫颈癌发病率,并确定在不同预算投入下实现消除子宫颈癌目标的最优防控策略。研究结果显示,若不增加子宫颈癌防控预算,到2100年,子宫颈癌发病率预计将达到2015年的3倍;若2020年开始采用优化的防控策略,即95%的12岁女孩接种HPV疫苗,扩大45岁女性终生一次宫颈癌筛查的覆盖率,使城市女性覆盖率达90%、农村女性覆盖率达33%,则预计2072(95%CI:2070—2074)年在城市、2074(95%CI:2072—2076)年在农村可实现消除子宫颈癌的目标;若预算不受限制,最早在2057年(2053—2060年)和2060年(2057—2063年)将分别在城市、农村消除子宫颈癌。中国可通过优化宫颈癌综合防控策略,尽早在适龄人群中引入HPV疫苗来实现消除宫颈癌的目标;并可通过增加预算来加速消除进程,大幅减少罹患子宫颈癌的人数。 | 赵宇倩 乔良(编译) Xia CF Hu SY Xu Xq | 2019 | 中华预防医学杂志2019，53，11： | 15 |
| 5 | 脑卒中后认知运动干预对步态和平衡影响显示文摘当认知和运动任务同时完成时,会发生认知运动干预(CMI)。该技术已用于运动医学康复来增强疗效。本综述和荟萃分析研究了在脑卒中患者中,CMI用于改善步态和平衡的疗效。本文检索了多个数据库,筛选出了发表于1972年到2014年间的随机对照试验——包括成年脑卒中患者CMI治疗组和对照组。主要评价指标为步态和平衡评定,次要评价指标为日常生活能力以及功能独立性评定。 | Wang XQ Pi YL Chen BL 吴毅 | 2015 | 中国康复2015，30，5： | 13 |
| 6 | GLOBAL SUPERCONVERGENCE ESTIMATES OF FINITE ELEMENT METHOD FOR SCHRODINGER EQUATION显示文摘In this paper, we shall study the initial boundary value problem of Schrodinger equation. The second order gradient superconvergence estimates for the problem are obtained solving by linear finite elements. | Lin, Q Liu, XQ | 1998 | Journal of Computational Mathematics1998，16，6： | 12 |
| 7 | Sedation and safety of propofol for therapeutic endoscopic retrograde cholangiopancreatography显示文摘Endoscopic retrograde cholangiopancrea tography(ERCP) is the most complex gastrointestinal procedure,which needs patients’ cooperation. The aim of this study was to observe the quality and safey of sedation with propofol in patients undergoing therapeutic ERCP. METHODS:Seventy patients who had undergone therapeutic ERCP were randomly divided into two groups.One group, given intravenously propofol, and the other sedated with routine method, served as the control. Blood pressure, heart rate,oxygen saturation were monitored and cardiorespiratory event was observed. Patient cooperation,performance, recovery time and amnesia served as variables postoperation. RESULTS:Blood pressure elevated in four patients in the propofol group, less than in the control group(P<0.01). Seven patients showed decreased blood pressure after administration of propofol,but none in the control group (P<0.01). Twelve patients in the control group showed mild or significant resistance, but none in the propofol group (P<0.01). The time for performance in the propofol group(P<0.05) was shorter than in the control group. Patient recovery was quicker in the propofol group than in the control group (P<0.01). The degree of amnesia better in the propofol group than in the control group ( P<0.01). The degree of amnesia was also better in the propofol group than in the control group (P<0.01). CONCLUSIONS:Propofol proves to be an excellent sedative for therapeutic ERCP. Being effective and safe, it shows a shorter ERCP duration but quick recovery and better amnesia. It is better than other routine sedatives. | Digestive Department (Chen WX, Lin HJ, Gu Q, Zhong XQ, Yu CH, Li YM and Gu ZY) and Department of Intensive Care Unit (Zhang WF), First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003 , China | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，3： | 10 |
| 8 | Microarray-based analysis of changes in diversity of microbial genes involved in organic carbon decomposition following land use/cover changes显示文摘 | Zhang YG Zhang XQ Liu XD Xiao Y Qu L J Wu LY Zhou JZ | 2007 | 中国生物学文摘2007，21，8： | 10 |
| 9 | 不同牙周状态正畸力诱导破骨细胞分化因子RANK在牙周组织的表达显示文摘目的研究不同牙周状态正畸力作用下破骨细胞分化因子RANK在牙周组织的表达变化,为牙周病正畸治疗提供参考。方法建立大鼠牙周炎静止期、牙周炎活动期模型,以50克力移动牙周正常组、牙周炎静止期组、牙周炎活动期组的上颌磨牙。分别于牙齿移动的第3和第7天处死大鼠。采用免疫组化和实时荧光定量PCR定性定量分析各组RANK在牙周组织的表达。结果正常牙周移动组RANKmRNA的表达高于正常对照组(P<0.05)。静止期牙齿移动组RANKmRNA在牙周组织的表达高于正常牙周移动组(P<0.01)。较活动期移动组显著减小(P<0.01)。牙周炎活动期牙齿移动组RANKmRNA的表达均高于其他各组(P<0.01)。结论 RANK参与调节正常牙周及牙周炎正畸牙齿移动。牙周炎静止期正畸力可诱导RANK的表达增加,但显著小于炎症活动期。此时要密切控制牙周易感因素。 | 陈莉 李小彤 范晓川 Wei XQ 王红梅 | 2015 | 北京口腔医学2015，23，2： | 6 |
| 10 | Induction of mucosal and systemic immune response by single-dose oral immunization with biodegradable microparticles containing DNA encoding HBsAg显示文摘 | He XW Wang F Jiang L Li J Liu SK Xiao ZY Jin XQ Zhang YN He Y Li K Guo YJ Sun SH | 2005 | 第二军医大学学报2005，26，10： | 5 |
| 11 | Simvastatin and niacin,antioxidant vitamins,or the combination for the prevention of coronary disease显示文摘 | Brown BG Zhao XQ Chait A | | the New England Journal of Medicine0，，： | 2 |
| 12 | Purification and characterization of intracellular toxin A of Clostridium difficile显示文摘 | Meng XQ Kamiya S Yamakawa K | 1993 | J Med Microbiol1993，38，： | 2 |
| 13 | Imbalance production between interleukin-1b (IL-1b) and IL-1 receptor antagonist (IL-1ra) in bronchial asthma显示文摘 | Mao XQ Kawai M Yamashita T | 2000 | Biochem Biophys Res Commun2000，276，2： | 1 |
| 14 | Effects of intragastric agmatine on morphine-induced physiological dependence in beagle dogs and rhesus monkeys 显示文摘 | SU RB LU XQ HUANG Y | 2008 | Eur J Pharmacol2008，587，13： | 1 |
| 15 | In vivo transfeetion of NF-κB decoy oligodeoxynucleotides attenuate renal ischemia/reperfusion injury in rats 显示文摘 | Cao CC Ding XQ Ou ZL | 2004 | Kidney Int2004，65，3： | 1 |
| 16 | Chronic morphine treatment and withdrawal induce up - regulation of c - Jun N - terminal kinase 3 gene expression in rat brain 显示文摘 | Fan XL Zhang JS Zhang XQ | 2003 | Neuroscience2003，122，： | 1 |
| 17 | Boron influences pollen germination and pollen tube growth in Picea meyeri显示文摘 | Lu LD Wu XQ | 2003 | Tree physiology2003，23，5： | 1 |
| 18 | Effect of salpingectomy on ovarian reserved funct ion显示文摘 | TANG XQ QIU Y LIU F | 2005 | Journal of Guangxi Medical University2005，22，3： | 1 |
| 19 | In vivo quantification of natural caries lesions using the quantitative light-induced fluorescence method-a reproducibility study显示文摘 | Tranaus SF Shi XQ Trollsas K | 2000 | SPIE2000，3910，： | 1 |
| 20 | Microsatellite alterations in plasma DNA of small cell lung cancer patients显示文摘 | Chen XQ Stroun M Magnenat JL | 1996 | Nat Medi1996，2，9： | 1 |
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