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| 1 | D-二聚体预测稳定型冠状动脉性心脏病患者的长期病因特异性死亡率、心血管事件和癌症显示文摘交联纤维蛋白的降解产物D-二聚体是高凝状态和血栓形成事件的标志。D-二聚体水平中度升高与血管疾病患者静脉和动脉事件的风险相关。在缺血性疾病长期普伐他汀干预(long-term intervention with pravastatin in ischemic disease,LIPID)试验中,研究者在存在其他危险因素的背景下,评估了D-二聚体水平在预测长期血管转归、病因特异性死亡率和新发癌症中的作用。 | 刘青 叶鹏 Simes J Robledo KP White HD Espinoza D Stewart RA Sullivan DR Zeller T Hague W Nestel PJ Glasziou PP Keech AC Elliott J Blankenberg S Tonkin AM LIPID study investigators | 2018 | 中华高血压杂志2018，26，3： | 6 |
| 2 | Pyruvate-fortified resuscitation stabilizes cardiac electrical activity and energy metabolism during hypovolemia显示文摘AIM: To test the hypothesis that fluid resuscitation with Ringer's solution enriched with pyruvate(PR), a physiological antioxidant and energy substrate, affords protection of myocardial metabolism and electrophysiological performance superior to lactated Ringer's(LR) during hypovolemia and hindlimb ischemia-reperfusion.METHODS: Male domestic goats(25-30 kg) were exsanguinated to a mean arterial pressure of 48 ± 1 mm Hg. Right hindlimb ischemia was imposed for 90 min by applying a tourniquet and femoral crossclamp. LR or PR, infused iv, delivered 0.05 mmol/kg per minute L-lactate or pyruvate, respectively, from 30 min hindlimb ischemia until 30 min post-ischemia. Time controls(TC) underwent neither hemorrhage, hindlimb ischemia nor resuscitation. Goats were sacrificed and left ventricular myocardium biopsied at 90 min fluid resuscitation(n = 6 per group) or 3.5 h later(n = 9 LR, 10 PR, 8 TC).RESULTS: Myocardial 8-isoprostane content, phosphocreatine phosphorylation potential, creatine kinase activity, and heart rate-adjusted QT interval(QTc) vari- ability were evaluated at 90 min resuscitation and 3.5 h post-resuscitation. PR sharply lowered pro-arrhythmic QTc variability vs LR(P < 0.05); this effect persisted 3.5 h post-resuscitation. PR lowered myocardial 8-isoprostane content, a product of oxidative stress, by 39 and 37% during and 3.5 h after resuscitation, respectively, vs LR. Creatine kinase activity fell 42% post-LR vs TC(P < 0.05), but was stable post-PR(P < 0.02 vs post-LR). PR doubled phosphocreatine phosphorylation potential, a measure of ATP free energy state, vs TC and LR(P < 0.05); this energetic enhancement persisted 3.5 h post-resuscitation.CONCLUSION: By augmenting myocardial energy state and protecting creatine kinase activity, pyruvateenriched resuscitation stabilized cardiac electrical function during central hypovolemia and hindlimb ischemiareperfusion. | Hunaid A Gurji Daniel W White Besim Hoxha Jie Sun Albert H Olivencia-Yurvati Robert T Mallet | 2013 | World Journal of Critical Care Medicine2013，2，4： | 3 |
| 3 | Vascular endothelial growth factor-D expression is an independent prognostic maker for survival in cotorectal carcinoma显示文摘 | White J D Hewett P W Kosuge D | | 0，，： | 2 |
| 4 | CD133 expression is not restricted to stem cells, and both CD133^sup +^ and CD133^sup -^ metastatic colon cancer cells initiate tumors显示文摘 | Shmelkov Sergey V Butler Jason M Hooper Andrea T Hormigo Adilia Kushner Jared Milde Till Clair Ryan St Baljevic Muhamed White Ian Jin David K Chadburn Amy Murphy Andrew J Valenzuela David M Gale Nicholas W Thurston Gavin Yancopoulos George | 2008 | Journal of Clinical Investigation2008，，： | 2 |
| 5 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 6 | Size-resolved measurements of light scattering by ambient particles in the southwestern U S显示文摘 | White W H Macias E S Ninenger R C | 1994 | Atmos Environ1994，28，： | 1 |
| 7 | Soil deformation measurement using particle image velocimetry (PIV) and photogrammetry显示文摘 | WHITE D J TAKE W A BOLTON M D | 2003 | Geotechnique2003，53，7： | 1 |
| 8 | Fabrication of homostructure ZnO p-n junctions显示文摘 | Kim W J White H M | 2000 | J Cryst Growth2000，219，： | 1 |
| 9 | Lossless Astronomical Image Compression and the Effects of Random Noise 显示文摘 | W D Pence R Seaman R L White | 2009 | Publications of the Astronomical Society of the Pacific2009，121，： | 1 |
| 10 | Biological costs and benefits to plant-microbe interactions in the rhizosphere 显示文摘 | Morgan J A W Bending G D White P J | 2005 | Journal of Experimental Botany2005，56，417： | 1 |
| 11 | Colloidal behaviour of materials with ionizable group surfaces显示文摘 | HEALY T W CHAN D WHITE L R | 1980 | Pure Appl Chem1980，52，5： | 1 |
| 12 | Sweet cherry fruit distribution and leaf populations: modeling canopy dynamics and management strategies显示文摘 | Lang G A Olmstead J W Whiting M D | 2004 | Aeta Hortic2004，636，： | 1 |
| 13 | Fungal molecular systematics显示文摘 | Bruns T D White T J Taylor J W | 1991 | Annu Rev Ecol System1991，22，： | 1 |
| 14 | Induction of collagenase and stromelysin gene expression by mechanic injury in vascular smooth - derived cell Line显示文摘 | James T W Wagner R White L A | 1993 | J cell physiol1993，157，： | 1 |
| 15 | Effects of chronic nifedipine on casual (office)and 24 hour ambulatoy blood pressure显示文摘 | White W B | 1985 | Clin Pharmacol Ther1985，38，1： | 1 |
| 16 | Positive feedbacks between the Antarctic circumpolar wave and the global El Nino oscillation wave显示文摘 | White W B Chen S C Allan R J | 2002 | J Geophys Res2002，107，10： | 1 |
| 17 | Effects of root-zone heating on elemental composition of calceolaria显示文摘 | White J W Biernbaum J A | 1984 | Journal of the American Society for Horticultural Science1984，109，3： | 1 |
| 18 | Partitioning of ocean and land up take of CO2 as inferred by δ 13 C measurements from the NOAA Climate Monitoring and Diagnostics laboratory global air sampling network显示文摘 | Ciais P Tans P P White J W C | 1995 | J Geophys Res1995，100，： | 1 |
| 19 | The identification of inhibine,the antibacterial factor in honey,as hydrogen peroxide and its origin in a honey glucose-oxidase system显示文摘 | WHITE J W SUBERS M H SCHEPARTZ A I | 1963 | Biochimica et Biophysica Acta1963，73，： | 1 |
| 20 | Higher - order spectra: the bispectrum and trispeetrum 显示文摘 | COLLIS W B WHITE P R HAMMOND J K | 1998 | Mechanical System and Signal Processing1998，12，3： | 1 |
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