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| 1 | Pulsating hydraulic fracturing technology in low permeability coal seams显示文摘Based on the difficult situation of gas drainage in a single coal bed of high gas content and low permeability, we investigate the technology of pulsating hydraulic pressure relief, the process of crank plunger movement and the mechanism of pulsating pressure formation using theoretical research, mathematical modeling and field testing. We analyze the effect of pulsating pressure on the formation and growth of fractures in coal by using the pulsating hydraulic theory in hydraulics. The research results show that the amplitude of fluctuating pressure tends to increase in the case where the exit is blocked, caused by pulsating pressure reflection and frictional resistance superposition, and it contributes to the growth of fractures in coal. The crack initiation pressure of pulsating hydraulic fracturing is 8 MPa, which is half than that of normal hydraulic fracturing; the pulsating hydraulic fracturing influence radius reaches 8 m.The total amount of gas extraction is increased by 3.6 times, and reaches 50 L/min at the highest point.The extraction flow increases greatly, and is 4 times larger than that of drilling without fracturing and 1.2times larger than that of normal hydraulic fracturing. The technology provides a technical measure for gas drainage of high gas content and low permeability in the single coal bed. | Wang Wenchao Li Xianzhong Lin Baiquan Zhai Cheng | 2015 | International Journal of Mining Science and Technology2015，25，4： | 9 |
| 2 | Size-controlled green synthesis of silver nanoparticles assisted by L-cysteine显示文摘在有 L 半胱氨酸的帮助的水的答案的银 nanoparticles (Ag NP ) 的绿、控制尺寸的合成被介绍。Ag NP 的尺寸随 L 半胱氨酸集中的增加减少,并且能被调整 L 半胱氨酸集中因此控制。有一般水准的 Ag NP 3 nm 缩放的 TEM 分析表演能面对 1.0 mmol/L L 半胱氨酸被生产, Ag NP 的大约 1:6 种尺寸当 L 半胱氨酸(17 nm ) 不在时获得了。assynthesized 银胶体的答案是稳定的并且没有任何降水,能在房间温度被存储为至少二个月。这 L 半胱氨酸帮助了方法简单、可行、有效,并且将便于 Ag NP 的生产和申请。 | Wenchao Zhang Lin Zhang Yan Sun | 2015 | Frontiers of Chemical Science and Engineering2015，9，4： | 3 |
| 3 | Clear mortality gap caused by graft macrosteatosis in Chinese patients after cadaveric liver transplantation显示文摘Background:Liver transplantation(LT)is one of the most effective surgical treatment for patients with end-stage liver disease.Steatosis is a contributor for inferior graft quality.But its impact and safety on transplantation was less assessed in Chinese patients.Methods:Graft steatosis and related information involved in recipients,donors and surgical procedures were retrospectively collected from 239 patients.Results:Donor macrosteatosis(MaS)caused about 2.14 and 2.80 folds of increment on patient and graft mortality.Dose-response analysis revealed prominent risk of grafts on overall patient/organ mortality when MaS content exceeded 10%(P<0.05).Noteworthy,deaths were only observed in MaS group when concurrent with extremely higher post-transplant alanine aminotransferase(ALT,64%).However,microsteatosis(MiS)grafts didn’t affect outcomes after LT.In a cohort of Chinese patients,MaS had comprehensive effects on post-transplant outcomes with relatively lower safety threshold at 10%.Mortality gap caused by MaS grafts was observed in patients with severer ischemia reperfusion injury.Conclusions:Our study revealled the graft MaS affected the post-transplant outcomes in lower risk cutoff in Chinese patients.Further study is worthy to validate these results and investigate inner mechanism under the phenomenon. | Zhengtao Liu Wenchao Wang Li Zhuang Jingfeng Liu Shuping Que Dan Zhu Linfang Dong Jian Yu Lin Zhou Shusen Zheng | 2020 | Hepatobiliary Surgery and Nutrition2020，9，6： | 2 |
| 4 | A Rapid Generation Method of Character Doll with Rotatable Limbs Oriented to 3D Printer显示文摘Currently,3D printing of the character dolls is a very practical application for the average person.But the model of doll which can be obtained is static so the posture of the doll is single.On the other hand,the modification of the model is very difficult to non-professions.This paper proposes an rapid generation method of character doll with rotatable limbs,which is through adding the sphere joint to the doll's model automatically.After the model is segmented by drawing a line interactively,the sphere joint is created based on the segmentation boundary through entity modeling method.Lastly the two models of the doll and the joint are composited and printed.Some doll's model are tested on the FDM(Fused Deposition Modeling)3D printer using this process.The results are more interesting and the efficiency has been greatly improved compared with modifying the model manually. | LI Lin CHU Xiao-li Nie Wenchao | 2014 | Computer Aided Drafting,Design and Manufacturing2014，24，1： | 2 |
| 5 | Evolutionary analysis of Omicron variant BF.7 and BA.5.2 pandemic in China显示文摘On December 7,2022,China adjusted public health control measures,there have been widespread of SARS-CoV-2 infections in Chinese mainland.As the number of infected people increased,the mutation probability of SARS-CoV-2 is also raised.Therefore,it is of great importance to monitor SARS-CoV-2 variants and its mutations in China.In this current study,665 SARS-CoV-2 genomes from China deposited in the public database were used to analyze the proportion of different variants;to determine the composition of variants in China across different provinces;and analyze specific mutation frequency,focusing on 12 immune escape residues.The results showed that no new mutations were generated on the 12 immune escape residues.The evolutionary analysis of the BF.7 variant circulating in China showed that there is an independent evolutionary branch with unique mutation sites,officially named BF.7.14 by PANGO.This variant may have been imported from Russia to Inner Mongolia at the end of September 2022 and continued its spread in China.The evolutionary analysis of BA.5.2 variant shows that the variant is composed of two sub-variants,named BA.5.2.48 and BA.5.2.49 by PANGO,respectively.This variant may have been imported from abroad to Beijing at the beginning of September 2022 and formed two sub-variants after domestic transmission.Finally,this study showed that current epidemic variants in China were already circulating in other countries,and there were no additional mutations on immune escape residues that could pose a threat to other countries. | Yamin Sun Min Wang Wenchao Lin Wei Dong Jianguo Xu | 2023 | Journal of Biosafety and Biosecurity2023，5，1： | 2 |
| 6 | Stress dependence of the creep behaviors and mechanisms of a third-generation Ni-based single crystal superalloy显示文摘Elevated temperature creep behaviors at 1100℃ over a wide stress regime of 120-174 MPa of a thirdgeneration Ni-based single crystal superalloy were studied. With a reduced stress from 174 to 120 MPa, the creep life increased by a factor of 10.5, from 87 h to 907 h, presenting a strong stress dependence. A splitting phenomenon of the close-(about 100 nm) and sparse-(above 120 nm) spaced dislocation networks became more obvious with increasing stress. Simultaneously, ao<010> superdislocations with low mobil让ies were frequently observed under a lower stress to pass through γ precipitates by a combined slip and climb of two ao<110> superpartials or pure climb. However, ao<110> superdislocations with higher mobility were widely found under a higher stress, which directly sheared into y precipitates. Based on the calculated critical resolved shear stresses for various creep mechanisms, the favorable creep mechanism was systematically analyzed. Furthermore, combined with the microstructural evolutions during different creep stages, the dominant creep mechanism changed from the dislocation climbing to Orowan looping and precipitates shearing under a stress regime of 137-174MPa, while the dislocation dim bing mechanism was operative throughout the whole creep stage un der a stress of 120 MPa, resulting a superior creep performanee. | Quanzhao Yue Lin Liu Wenchao Yang Chuang He Dejian Sun Taiwen Huang Jun Zhang Hengzhi Fu | 2019 | Journal of Materials Science & Technology2019，35，5： | 2 |
| 7 | Formation mechanisms and control method for stray grains at melt-back region of Ni-based single crystal seed显示文摘An experimental study together with numerical simulation was conducted to investigate the formation mechanisms and control methods for stray grains at melt-back of seed in this paper.The numerical simulation results showed that the convex solid/liquid(S/L)interface changed very slowly into a concave interface during the initial solidification stage and the undercooling was slightly affected by the S/L curvature change.The formation of stray grains below melt-back interface at seed perimeter could be suppressed with the decrease of clearance between the seed and mold.However when the clearance was further decreased to 0,an orientation deviation layer formed originated from the deformation of un-melted seed caused by different expend coefficient between the seed and mold.The nucleation of stray grains above the melt-back interface at the seed perimeter could be suppressed using the mold with small surface roughness.The isolated un-melted dendrite stem at semi-solid mushy of the seed with the large original primary dendrite spacing transfer to complex network structure,suppressing the formation of the stray grains,when the primary dendrite spacing of seed decreased or the seed underwent solution heat treatment.Then,the formation mechanisms of the stray grains at the melt-back region are discussed based on above results,and a method is proposed to suppress the formation of the stray grains for preparing single crystal components by re-used seed . | Songsong Hu Wenchao Yang Zhuoran Li Hanyuan Xu Taiwen Huang Jun Zhang Haijun Su Lin Liu | 2021 | Progress in Natural Science:Materials International2021，31，4： | 2 |
| 8 | Rosuvastatin May Reduce the Incidence of Cardiovascular Events in Patients with Acute Coronary Syndromes Receiving Percutaneous Coronary Intervention by Suppressing miR‐155/ SHIP ‐1 Signaling Pathway显示文摘 | Wenchao Xie Ping Li Zhengdong Wang Jian Chen Zhihai Lin Xiangwen Liang Yingxi Mo | 2014 | Cardiovasc Ther2014，，6： | 1 |
| 9 | Tailoring Microstructure and Microsegregation in a Directionally Solidified Ni-Based SX Superalloy by a Weak Transverse Static Magnetic Field显示文摘A weak transverse static magnetic field(WTSMF,0–0.5 T)is applied to the directional solidification process of a DD3 Ni-based SX superalloy,aiming to tailor the microstructure and microsegregation of alloys.The mechanisms of microstructural refinement and microsegregation distribution caused by a WTSMF during directional solidification are discussed.It is shown that the primary dendrite arm spacing is rapidly reduced from 181 to 143μm,and the average size ofγ′phase is significantly refined from 0.85 to 0.25μm as the magnetic field increases from 0 to 0.5 T.At the same time,the volumefractions ofγ/γ′eutectic and the segregation coefficient are also gradually decreased.The 3D numerical simulations of the multiscale convection in liquid phase show that the modifications of the microstructure and microsegregation in DD3 are mainly attributed to the enhanced liquid flow caused by thermoelectric magnetic convection(TEMC)at dendrite/sample scale under the WTSMF.The maximum of the TEMC increases with increasing the magnetic field intensity.This work paves a simple way to optimize the microstructure and microsegregation in directionally solidified Ni-based SX superalloys without changing the processing parameters and composition. | Yong Zhao Haijun Su Guangrao Fan Chenglin Liu Taiwen Huang Wenchao Yang Jun Zhang Lin Liu Hengzhi Fu | 2022 | Acta Metallurgica Sinica(English Letters)2022，35，7： | 1 |
| 10 | Spatial-Modulated Physical-Layer Network Coding Based on Block Markov Superposition Transmission for Maritime Relay Communications显示文摘As an alternative to satellite communications,multi-hop relay networks can be deployed for maritime long-distance communications.Distinct from terrestrial environment,marine radio signals are affected by many factors,e.g.,weather conditions,evaporation ducting,and ship rocking caused by waves.To ensure the data transmission reliability,the block Markov superposition transmission(BMST)codes,which are easily configurable and have predictable performance,are applied in this study.Meanwhile,the physical-layer network coding(PNC)scheme with spatial modulation(SM)is adopted to improve the spectrum utilization.For the BMST-SMPNC system,we propose an iterative algorithm,which utilizes the channel observations and the a priori information from BMST decoder,to compute the soft information corresponding to the XORed bits constructed by the relay node.The results indicate that the proposed scheme outperforms the convolutional coded SM-PNC over fast-fading Rician channels.Especially,the performance can be easily improved in high spatial correlation maritime channel by increasing the memory m. | Yao Shi Liming Zheng Wenchao Lin Xiao Ma | 2020 | China Communications2020，17，3： | 1 |
| 11 | Environmental behavior, human health effect, and pollution control of heavy metal(loid)s toward full life cycle processes显示文摘Heavy metal(loid)s(HMs)have caused serious environmental pollution and health risks.Although the past few years have witnessed the achievements of studies on environmental behavior of HMs,the related toxicity mechanisms,and pollution control,their relationship remains a mystery.Researchers generally focused on one topic independently without comprehensive considerations due to the knowledge gap between environmental science and human health.Indeed,the full life cycle control of HMs is crucial and should be reconsidered with the combination of the occurrence,transport,and fate of HMs in the environment.Therefore,we started by reviewing the environmental behaviors of HMs which are affected by a variety of natural factors as well as their physicochemical properties.Furthermore,the related toxicity mechanisms were discussed according to exposure route,toxicity mechanism,and adverse consequences.In addition,the current state-of-the-art of available technologies for pollution control of HMs wastewater and solid wastes were summarized.Finally,based on the research trend,we proposed that advanced in-operando characterizations will help us better understand the fundamental reaction mechanisms,and big data analysis approaches will aid in establishing the prediction model for risk management. | Haoyu Deng Yuling Tu Han Wang Ziyi Wang Yanyu Li Liyuan Chai Wenchao Zhang Zhang Lin | 2022 | Eco-Environment & Health2022，1，4： | 1 |
| 12 | Mechanoluminescent hybrids from a natural resource for energy-related applications显示文摘Mechanoluminescent(ML)materials that directly convert mechanical energy into photon emission have emerged as promising candidates for various applications.Despite the recent advances in the development of both novel and conventional ML materials,the limited access to ML materials that simultaneously have the attributes of high brightness,low cost,self-recovery,and stability,and the lack of appropriate designs for constructing ML devices represent significant challenges that remain to be addressed to boost the practical application of ML materials.Herein,ML hybrids derived from a natural source,waste eggshell,with the aforementioned attributes are demonstrated.The introduction of the eggshell not only enables the preparation of the hybrid in a simple and cost-effective manner but also contributes to the homochromatism(red,green,or blue emission),high brightness,and robustness of the resultant ML hybrids.The significant properties of the ML hybrids,together with the proposed structural design,such as porosity or core–shell structure,could expedite a series of mechanic-optical applications,including the self-luminous shoes for the conversion of human motions into light and light generators that efficiently harvest water wave energy.The fascinating properties,versatile designs,and the efficient protocol of“turning waste into treasure”of the ML hybrids represent significant advances in ML materials,promising a leap to the practical applications of this flouring material family. | Chunfeng Wang Ronghua Ma Dengfeng Peng Xianhu Liu Jing Li Boru Jin Aixian Shan Yu Fu Lin Dong Wenchao Gao Zhong Lin Wang Caofeng Pan | 2021 | InfoMat2021，3，11： | 1 |
| 13 | Origin and evolutionary analysis of the SARS-CoV-2 Omicron variant显示文摘The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has evolved rapidly into new variants throughout the pandemic.The Omicron variant has more than 50 mutations when compared with the original wild-type strain and has been identified globally in numerous countries.In this report,we analyzed the mutational profiles of several variants,including the per-site mutation rate,to determine evolutionary relationships.The Omicron variant was found to have a unique mutation profile when compared with that of other SARS-CoV-2 variants,containing mutations that are rare in clinical samples.Moreover,the presence of five mouse-adapted mutation sites suggests that Omicron may have evolved in a mouse host.Mutations in the Omicron receptor-binding domain(RBD)region,in particular,have potential implications for the ongoing pandemic. | Yamin Sun Wenchao Lin Wei Dong Jianguo Xu | 2022 | Journal of Biosafety and Biosecurity2022，4，1： | 1 |
| 14 | Influence of withdrawal rate on the porosity in a third-generation Ni-based single crystal superalloy显示文摘The influence of withdrawal rate on the porosity in a third-generation Ni-based single crystal superalloy was investigated by a quantitative evaluation method. The results showed that the withdrawal rate obviously effected on the average area fraction, number and diameter of porosities except their radius ratios. In consideration of the microstructure observation for dendrite arms, an optimized withdrawal rate was obtained with a minimum porosity level as about 125 μm s^(-1). Simultaneously, a threshold value for the acceptance level of porosities might be set as about 0.1% in order to fulfill the requirements for Ni-based single crystal casting in laboratory scale. Finally, the formation reason of porosity was discussed and it was concluded that the feeding for the volume shrinkage of the last solidified eutectic liquids from the residual liquids and the isolating effect of the morphologies of dendrite arms might be two key factors in controlling the porosities level in Ni-based single crystal superalloy. | Quanzhao Yue Lin Liu Wenchao Yang Taiwen Huang Jun Zhang Hengzhi Fu Xinbao Zhao | 2017 | Progress in Natural Science:Materials International2017，27，2： | 1 |
| 15 | The structure of 4-hydroxylphenylpyruvate dioxygenase complexed with 4-hydroxylphenylpyruvic acid reveals an unexpected inhibition mechanism显示文摘4-Hydroxyphenylpyruvate dioxygenase(HPPD)is an important target for both drug and pesticide discovery.As a typical Fe(II)-dependent dioxygenase,HPPD catalyzes the complicated transformation of 4-hydroxyphenylpyruvic acid(HPPA)to homogentisic acid(HGA).The binding mode of HPPA in the catalytic pocket of HPPD is a focus of research interests.Recently,we reported the crystal structure of Arabidopsis thaliana HPPD(At HPPD)complexed with HPPA and a cobalt ion,which was supposed to mimic the pre-reactive structure of At HPPD-HPPA-Fe(II).Unexpectedly,the present study shows that the restored At HPPD-HPPA-Fe(II)complex is still nonreactive toward the bound dioxygen.QM/MM and QM calculations reveal that the HPPA resists the electrophilic attacking of the bound dioxygen by the trim of its phenyl ring,and the residue Phe381 plays a key role in orienting the phenyl ring.Kinetic study on the F381 A mutant reveals that the HPPD-HPPA complex observed in the crystal structure should be an intermediate of the substrate transportation instead of the pre-reactive complex.More importantly,the binding mode of the HPPA in this complex is shared with several well-known HPPD inhibitors,suggesting that these inhibitors resist the association of dioxygen(and exert their inhibitory roles)in the same way as the HPPA.The present study provides insights into the inhibition mechanism of HPPD inhibitors. | Xiaoning Wang Hongyan Lin Junjun Liu Xinyun Zhao Xi Chen Wenchao Yang Guangfu Yang Chang-guo Zhan | 2021 | Chinese Chemical Letters2021，32，6： | 1 |
| 16 | Ultra-stable and color-tunable manganese ions doped lead-free cesium zinc halides nanocrystals in glasses for light-emitting applications显示文摘All inorganic CsPbX_(3)(X=Cl,Br,and I)perovskite nanocrystals have made unprecedented radical progresses for opto-electronic applications,but their instability and toxicity of lead impede their wide applications.Herein,we report the first precipitation of leadfree Mn:Cs_(2)ZnX_(4) nanocrystals in glasses.Efficient green and red photoluminescence are realized from these Mn:Cs_(2)ZnX_(4 )nanocrystals in glasses.By adjusting the size and halide component in these nanocrystals,coordination environment of Mn^(2+)ions can be tuned,leading to tunable photoluminescence with improved quantum efficiency.It is illustrated that in-situ precipitation of these Mn:Cs_(2)ZnX_(4) nanocrystals in glasses significantly improves their thermal-,chemical-,and photo-stabilities,making them promising for light-emitting diodes with stable chromaticity coordinates. | Kai Li Ying Ye Wenchao Zhang Yao Zhou Yudong Zhang Shisheng Lin Hang Lin Jian Ruan Chao Liu | 2022 | Nano Research2022，15，10： | 1 |
| 17 | Downregulation of p53-inducible microRNAs 192 , 194 , and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development显示文摘 | Flavia Pichiorri Sung-Suk Suh Alberto Rocci Luciana De Luca Cristian Taccioli Ramasamy Santhanam Wenchao Zhou Don M. Benson Craig Hofmainster Hansjuerg Alder Michela Garofalo Gianpiero Di Leva Stefano Volinia Huey-Jen Lin Danilo Perrotti Michael Kuehl Ram | 2010 | Cancer Cell2010，，4： | 1 |
| 18 | Enhanced comprehensive properties of stereolithography 3D printed alumina ceramic cores with high porosities by a powder gradation design显示文摘Ceramic cores with complex structures and optimized properties are critical for hollow turbine blades applied in aeroengines.Compared to traditional methods,additive manufacturing(AM)presents great advantages in forming complex ceramic cores,but how to balance the porosity and strength is an enormous challenge.In this work,alumina ceramic cores with high porosity,moderate strength,and low high-temperature deflection were prepared using stereolithography(SLA)3D printing by a novel powder gradation design strategy.The contradiction between porosity and flexural strength is well adjusted when the mass ratio of the coarse,medium,and fine particles is 2:1:1 and the sintering temperature is 1600℃.The fracture mode of coarse particles in sintered SLA 3D printing ceramic transforms from intergranular fracture to transgranular fracture with the increase of sintering temperature and the proportion of fine powders in powder system.The sintered porosity has a greater influence on the high-temperature deflection of SLA 3D printed ceramic cores than grain size.On this basis,a'non-skeleton'microstructure model of SLA 3D printed alumina ceramic cores is created to explain the relationship between the sintering process and properties.As a result,high porosity(36.4%),appropriate strength(50.1 MPa),and low high-temperature deflection(2.27 mm)were achieved by optimizing particle size gradation and sintering process,which provides an insight into the important enhancement of the comprehensive properties of SLA 3D printed ceramic cores. | Xiang Li Haijun Su Dong Dong Di Zhao Yuan Liu Zhonglin Shen Hao Jiang Yinuo Guo Haifang Liu Guangrao Fan Wenchao Yang Taiwen Huang Jun Zhang Lin Liu Hengzhi Fu | 2022 | Journal of Materials Science & Technology2022，，36： | 1 |
| 19 | A new MRI approach for accurately implanting microelectrodes into deep brain structures of the rhesus monkey (Macaca mulatta)显示文摘 | Jing W Wenchao W Lin L | 2010 | J Neurosci Methods2010，193，2： | 1 |
| 20 | Glio- hlastoma stem cells generate vascular pericytes to support vessel function and tumor growth 显示文摘 | CHENG Lin HUANG Zhi ZHOU Wenchao | 2013 | Cell2013，153，1： | 1 |
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